Name: Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG
Price range: $103 total
Rating: 8.8

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Your South Carolina Midlands Vacation

Whether you're heading to South Carolina Midlands for its rich history, spectacular views or something else entirely, this destination is one you won't forget in a hurry. Create your ultimate break with one of our South Carolina Midlands vacation packages. With so much to see and do on a trip to South Carolina Midlands, it can be difficult to know where to start. Kick off your travels in Columbia at Riverbanks Zoo and Garden and Williams Brice Stadium — two popular attractions here. Another city worthy of a spot on your itinerary is Florence. Don't miss Magnolia Mall and Mcleod Regional Medical Center. Expedia has flights, hotels, car rentals and more to help you create your very own customized South Carolina Midlands vacation today.

The Latest South Carolina Midlands vacation packages

Price found within the past 48 hours. Click for updated prices.

Fin's Inn

Save 100% on your flight

$247

per person

Apr 12 - Apr 17

found 1 day ago

Roundtrip flight included

Boston (BOS) to Myrtle Beach (MYR)

7.2/10 Good! (46 reviews)

Sands Ocean Club Resort

Save 100% on your flight

$298

per person

Apr 15 - Apr 20

found 1 day ago

Roundtrip flight included

Boston (BOS) to Myrtle Beach (MYR)

7.4/10 Good! (2,702 reviews)

Overall my wife and I enjoyed the hotel. The only issue was there was one bug on the beds. Otherwise no issues

Reviewed on Feb 9, 2026

The Ellie Beach Resort Myrtle Beach, Tapestry By Hilton

Save 100% on your flight

$482

per person

Apr 15 - Apr 20

found 1 day ago

Roundtrip flight included

Boston (BOS) to Myrtle Beach (MYR)

8.6/10 Excellent! (443 reviews)

Our room was spotless, the staff was warm and friendly, and the Ocean Blue restaurant was too notch.

Reviewed on Feb 3, 2026

Westgate Myrtle Beach Oceanfront Resort

Save 100% on your flight

$514

per person

Apr 15 - Apr 20

found 1 day ago

Roundtrip flight included

Boston (BOS) to Myrtle Beach (MYR)

8.4/10 Very Good! (1,006 reviews)

Excellent Ocean Views, clean room👌 I super recommend

Reviewed on Feb 8, 2026

Grand Atlantic Ocean Resort

Save 100% on your flight

$418

per person

Apr 15 - Apr 20

found 1 day ago

Roundtrip flight included

Boston (BOS) to Myrtle Beach (MYR)

8.8/10 Excellent! (1,017 reviews)

Room was great, kitchen well stocked. Kids had a blast in the pools.

Reviewed on Jan 30, 2026

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Where to stay in South Carolina Midlands

Find the best South Carolina Midlands areas and neighborhoods for the activities you enjoy most. Learn more about South Carolina Midlands

Downtown Columbia

3 out of top 10 points of interest in this area

A magnet for visitors to the southeast, this compact city is a favorite for its charm, cuisine, historic neighborhoods, world-class museums and pretty green spaces.

Discover the most popular places to visit in South Carolina Midlands

South Carolina Midlands featuring a sunset and a city

Fort Jackson

After visiting Fort Jackson, make a plan to see the other sights and activities in Columbia. You can attend a sporting event while in the area.

Carowinds Theme Park

Choose from 13 roller coasters, chase your friends in a bumper car, enjoy the water slides and beaches of Boomerang Bay, and walk with dinosaurs.

Riverbanks Zoo and Garden

Why not meet the animals who call Riverbanks Zoo and Garden home during your trip to Columbia? You can attend a sporting event while in the area.

South Carolina Midlands Hotel Deals

Hilton Garden Inn Columbia/Harbison

434 Columbiana Dr Columbia SC

Fully refundableReserve now, pay when you stay

$89 nightly

$100 total

Feb 15 - Feb 16

Total with taxes and fees

8.8/10 Excellent! (1,963 reviews)

Love it

Reviewed on Feb 7, 2026

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

7333 Garners Ferry Rd Columbia SC

Fully refundableReserve now, pay when you stay

$84 nightly

$94 total

Mar 1 - Mar 2

Total with taxes and fees

7.6/10 Good! (1,017 reviews)

Great room

Reviewed on Feb 2, 2026

Holiday Inn Express & Suites Columbia-I-26 @ Harbison Blvd by IHG

211 Lanneau Ct Columbia SC

Fully refundable

$93 nightly

$103 total

Feb 15 - Feb 16

Total with taxes and fees

8.8/10 Excellent! (1,027 reviews)

Clean room

Reviewed on Feb 5, 2026

See all 3,160 properties in South Carolina Midlands

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.