Name: Park Inn by Radisson Florence, SC
Price range: $95 total
Rating: 8.8

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Your South Carolina Midlands Vacation

Whether you're heading to South Carolina Midlands for its rich history, spectacular views or something else entirely, this destination is one you won't forget in a hurry. Create your ultimate break with one of our South Carolina Midlands vacation packages. With so much to see and do on a trip to South Carolina Midlands, it can be difficult to know where to start. Kick off your travels in Columbia at Riverbanks Zoo and Garden and Williams Brice Stadium — two popular attractions here. Another city worthy of a spot on your itinerary is Florence. Don't miss Magnolia Mall and Mcleod Regional Medical Center. Expedia has flights, hotels, car rentals and more to help you create your very own customized South Carolina Midlands vacation today.

The Latest South Carolina Midlands vacation packages

Price found within the past 48 hours. Click for updated prices.

Sands Ocean Club Resort

Save 100% on your flight

$298

per person

Apr 13 - Apr 18

found 1 day ago

Roundtrip flight included

Boston (BOS) to Myrtle Beach (MYR)

7.4/10 Good! (2,702 reviews)

Wi-Fi and beach view was excellent and staff was very polite and helpful

Reviewed on Jan 23, 2026

Westgate Myrtle Beach Oceanfront Resort

$555

per person

Mar 14 - Mar 21

found 1 day ago

Roundtrip flight included

Boston (BOS) to Myrtle Beach (MYR)

8.4/10 Very Good! (1,006 reviews)

Absolutely loved the stay @ Westgate Resort, clean nice environment, with great staff

Reviewed on Jan 19, 2026

Hilton Myrtle Beach Resort

Arcadian Shores

Save 100% on your flight

$409

per person

Apr 13 - Apr 18

found 1 day ago

Roundtrip flight included

Boston (BOS) to Myrtle Beach (MYR)

7.8/10 Good! (1,007 reviews)

The room was perfect! Love staying there!

Reviewed on Jan 11, 2026

Grand Atlantic Ocean Resort

Save 100% on your flight

$375

per person

Apr 13 - Apr 18

found 1 day ago

Roundtrip flight included

Boston (BOS) to Myrtle Beach (MYR)

8.8/10 Excellent! (1,017 reviews)

Overall, a good 2 night stay. The bed was very comfortable. The shower felt amazing. The smart TV was very much appreciated. I must note my suggestions, though. The area rug in the middle of the room needs to be trashed. Tripping hazard & dirty. We tripped over it so many times & had to place something on top of the corners just not to keep tripping. The room doesn't even need the rug. Would look so much cleaner without it. No rug needed. The refrigerator & microwave needs to be upgraded to stain steel. Those 2 changes would make this room appear much more cleaner & updated. Also, the towels should be WHITE. The wall colors / trim should all match. Those changes would do WONDERS & they're fairly inexpensive to do. Overall, we enjoyed our stay but the rug was a negative. I wanted to move it completely myself.

Reviewed on Jan 9, 2026

Marina Inn At Grande Dunes

Save 100% on your flight

$730

per person

Apr 13 - Apr 18

found 1 day ago

Roundtrip flight included

Boston (BOS) to Myrtle Beach (MYR)

9.4/10 Exceptional! (1,738 reviews)

I loved that this hotel offered a kiddie pool and the hot tub’s temperature was perfect. The property was serene and our room had a lovely view of the intracoastal highway. My kids loved sitting in the rocking chairs and watching the boat go by.

Reviewed on Jan 19, 2026

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Where to stay in South Carolina Midlands

Find the best South Carolina Midlands areas and neighborhoods for the activities you enjoy most. Learn more about South Carolina Midlands

Downtown Columbia

2 out of top 10 points of interest in this area

A magnet for visitors to the southeast, this compact city is a favorite for its charm, cuisine, historic neighborhoods, world-class museums and pretty green spaces.

Discover the most popular places to visit in South Carolina Midlands

South Carolina Midlands featuring a sunset and a city

Fort Jackson

4.5/5(662 reviews)

After visiting Fort Jackson, make a plan to see the other sights and activities in Columbia. You can attend a sporting event while in the area.

Carowinds Theme Park

4.5/5(482 reviews)

Choose from 13 roller coasters, chase your friends in a bumper car, enjoy the water slides and beaches of Boomerang Bay, and walk with dinosaurs.

Great place for a date or to be with the family!

Riverbanks Zoo and Garden

4.5/5(213 reviews)

Why not meet the animals who call Riverbanks Zoo and Garden home during your trip to Columbia? You can attend a sporting event while in the area.

South Carolina Midlands Hotel Deals

Hilton Garden Inn Columbia/Harbison

434 Columbiana Dr Columbia SC

Fully refundableReserve now, pay when you stay

$89 nightly

$100 total

Feb 1 - Feb 2

Total with taxes and fees

8.8/10 Excellent! (1,936 reviews)

Great stay!

Reviewed on Jan 20, 2026

La Quinta Inn by Wyndham Columbia SE / Fort Jackson

7333 Garners Ferry Rd Columbia SC

$75 nightly

$84 total

Feb 1 - Feb 2

Total with taxes and fees

7.6/10 Good! (1,001 reviews)

Rooms updated excellent appearance. Room ac had some extra vibration sound to deal with and bat vent fan a little noisy needed to be tightened up. Food good coffee and hot water not enough closer to warm. Arrival erson was more friendly and pleasant compared to check out person. Overall very impressed ...

Reviewed on Jan 13, 2026

Park Inn by Radisson Florence, SC

1729 Mandeville Road Florence SC

Fully refundable

$85 nightly

$95 total

Feb 8 - Feb 9

Total with taxes and fees

8.8/10 Excellent! (2,252 reviews)

Spotless and friendly

Reviewed on Jan 24, 2026

See all 3,139 properties in South Carolina Midlands

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.