Clayton, MO

St. Louis

Clayton
Photo by Najib Tecle
Photo by kirk allen
Photo by Sarah Mather

Popular places to visit

Things to do


Clayton Hotel Deals

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
$98 nightly
The price is $115 total per night from Dec 19 to Dec 20
$115 total
Dec 19 - Dec 20
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a 24-hour fitness center. Our guests praise the breakfast and ...
8.8/10 Excellent! (3,023 reviews)
This hotel was great, quiet area , yet located close enough to things

Reviewed on Dec 2, 2025

Clayton Plaza Hotel & Extended Stay
AC Hotel St. Louis Clayton

AC Hotel St. Louis Clayton

3 out of 5
227 South Central Ave St. Louis MO
$122 nightly
The price is $142 total per night from Dec 14 to Dec 15
$142 total
Dec 14 - Dec 15
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Popular attractions St. Louis Zoo and Forest Park ...
9/10 Wonderful! (221 reviews)
The staff were very helpful while there! I recommend doing valet instead of self parking so you wouldn’t have to go through any hassle with finding a parking space but overall my stay was great. The bed was really comfy. I would definitely stay there again when visiting St Louis.

Reviewed on Nov 25, 2025

AC Hotel St. Louis Clayton
Hampton Inn & Suites Clayton/St. Louis-Galleria Area

Hampton Inn & Suites Clayton/St. Louis-Galleria Area

3 out of 5
216 N Meramec Ave St. Louis MO
$111 nightly
The price is $131 total per night from Dec 14 to Dec 15
$131 total
Dec 14 - Dec 15
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free WiFi, and a fitness center. Our guests praise the helpful staff in our reviews. ...
8.8/10 Excellent! (902 reviews)
Onsite parking was great!

Reviewed on Dec 1, 2025

Hampton Inn & Suites Clayton/St. Louis-Galleria Area
Le Méridien St. Louis Clayton

Le Méridien St. Louis Clayton

4 out of 5
7730 Bonhomme Ave St. Louis MO
$119 nightly
The price is $140 total per night from Dec 19 to Dec 20
$140 total
Dec 19 - Dec 20
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy an outdoor pool, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the helpful ...
8.8/10 Excellent! (675 reviews)
Small rooms but beautiful lobby.

Reviewed on Oct 27, 2025

Le Méridien St. Louis Clayton
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

4 out of 5
421 N 8th St St. Louis MO
$101 nightly
The price is $120 total per night from Dec 11 to Dec 12
$120 total
Dec 11 - Dec 12
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Louis. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff and the ...
8.6/10 Excellent! (1,146 reviews)
Beautiful hotel. Wonderful atmosphere. Clean rooms. Would definitely stay there again.

Reviewed on Dec 4, 2025

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport

2.5 out of 5
10810 Pear Tree Ln St. Ann MO
$90 nightly
The price is $106 total per night from Dec 10 to Dec 11
$106 total
Dec 10 - Dec 11
Total with taxes and fees
Book a stay at this business-friendly hotel in St. Ann. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (2,742 reviews)
Room was clean and staff courteous.

Reviewed on Dec 3, 2025

Pear Tree Inn St. Louis Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Clayton

#lifeatexpedia

Dogtown

If you're looking for some top things to see and do in Dogtown and surrounding area, you can visit St. Louis Zoo and St. Louis Art Museum.

Dogtown
New Loop Trolley at Delmar St Louis

University City

Noted for its shopping and restaurants, there's plenty to explore in University City. Top attractions like St. Louis Black Repertory Company and Center of Creative Arts are major draws, and you can hop on the metro at Forsyth Station or U City Big Bend Station to see more of the city.

University City
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Ladue

The restaurants and churches are a few reasons travelers visit Ladue. Though there aren't many top sights in the neighborhood, you can visit Saint Louis Galleria Mall and Bella Vita Wines, a few notable attractions nearby.

Ladue
Fantastic toasted ravioli, a quintessential St. Louis dish. Excellent restaurant located on the Hill, a large Italian neighborhood.
#localgem #Delicious

The Hill

If you're looking for some top things to see and do in The Hill and surrounding area, you can visit St. Louis Science Center and Missouri Botanical Gardens and Arboretum.

The Hill
Central West End

Central West End

4.5/5(450 area reviews)

Bordering Forest Park with free cultural institutions, this St. Louis neighborhood boasts a bustling commercial district along Euclid Avenue and the world's largest mosaic collection at the Cathedral Basilica of Saint Louis.

Central West End
Not just bars but also loft apartments are lit in rainbow lights for Pride weekend in the Grove neighborhood in St. Louis! #LifeAtExpedia

The Grove

The Grove might not have many top sights, but St. Louis Science Center and Missouri Botanical Gardens and Arboretum are two attractions nearby that you can check out.

The Grove


Clayton, MO

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