Title: Top Independent in Syracuse - Expedia.com [Syracuse Travel Guide](https://expedia.com/Syracuse.dx4912)[Hotels in Syracuse](https://expedia.com/Syracuse-Hotels.d4912.Travel-Guide-Hotels)[Vacation Rentals in Syracuse](https://expedia.com/Syracuse-Vacation-Rentals.d4912.Travel-Guide-VacationRentals)[Flights to Syracuse](https://expedia.com/Cheap-Flights-To-Syracuse.d4912.Travel-Guide-Flights)[Things to do in Syracuse](https://expedia.com/Things-To-Do-In-Syracuse.d4912.Travel-Guide-Activities)[Car Rentals in Syracuse](https://expedia.com/Car-Rentals-In-Syracuse.d4912.Car-Rental-Guide)[Syracuse Vacation Packages](https://expedia.com/Syracuse.d4912.Destination-Travel-Guides) ![Syracuse, panoramic phot of the Roman Amphitheatre at Syracuse (Siracusa), UNESCO World Heritage Site, Sicily, Italy, Europe](https://images.trvl-media.com/place/4912/0fad57c8-f045-437c-be3c-817a684ac32e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/4912/0fad57c8-f045-437c-be3c-817a684ac32e.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Apr 7 - Apr 8](https://www.expedia.com/Hotel-Search?regionId=4912&startDate=2026-04-07&endDate=2026-04-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Apr 8 - Apr 9](https://www.expedia.com/Hotel-Search?regionId=4912&startDate=2026-04-08&endDate=2026-04-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=4912&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 17 - Apr 19](https://www.expedia.com/Hotel-Search?regionId=4912&startDate=2026-04-17&endDate=2026-04-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSyracuse-Hotels-Independent.0-0-d4912--bIndependent.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSyracuse-Hotels-Independent.0-0-d4912--bIndependent.Travel-Guide-Filter-Hotels) ## Top Syracuse Hotel Reviews ![Maecò Ortigia B&B](https://images.trvl-media.com/lodging/28000000/27370000/27369700/27369601/955b55b4_y.jpg) ### Maecò Ortigia B&B 10/10 Excellent "The breakfast menu was very diverse. Things were fresh and tasty. All varieties of coffee served. The people serving were exceptionally welcoming in hospitable. It was a wonderful place to start the day having a delicious breakfast. The property was wonderful one of our favorite places to stay during our three weeks of travel around Italy in Sicily Martina, who first greeted this was so thoughtful caring suggested places to go for history also places to eat, even where to get our laundry done she has an excellent Host and made the day id. I would stay here again in a heartbeat." [](https://expedia.com/Syracuse-Hotels-Maeco-Ortigia-BB.h27369601.Hotel-Information) ![Algila' Ortigia Charme Hotel](https://images.trvl-media.com/lodging/2000000/1890000/1883500/1883438/b9b70cd2_y.jpg) ### Algila' Ortigia Charme Hotel 10/10 Excellent "The hotel was really charming. Excellent location in Ortigia. Breakfast was really good. Would definitely recommend staying here. " [](https://expedia.com/Syracuse-Hotels-Algila-Ortigia-Charme-Hotel.h1883438.Hotel-Information) ![ Palazzo Artemide - VRetreats, SLH Collection](https://images.trvl-media.com/lodging/1000000/980000/974100/974007/e466bf8a_y.jpg) ### Palazzo Artemide - VRetreats, SLH Collection 10/10 Excellent "An exceptional experience from start to finish. " [](https://expedia.com/Syracuse-Hotels-Palazzo-Artemide-VRetreats.h974007.Hotel-Information) ![Grand Hotel Ortigia Siracusa](https://images.trvl-media.com/lodging/2000000/1330000/1329500/1329454/ac752df8_y.jpg) ### Grand Hotel Ortigia Siracusa 10/10 Excellent "Beautiful facility, classic. Wonderful restaurant for breakfast and dinner." [](https://expedia.com/Syracuse-Hotels-Grand-Hotel-Ortigia-Siracusa.h1329454.Hotel-Information) ![Lanterne Magiche Ortigia](https://images.trvl-media.com/lodging/19000000/18710000/18704100/18704044/266affcc_y.jpg) ### Lanterne Magiche Ortigia 8/10 Good "the room was spacious (we had a bedroom and a kitchen with a couch- the ocean view was debatable ( you can only see the ocean if you stand right in front of a high window ) - the terrace is lovely, the breakfast was ok but no vegan options" [](https://expedia.com/Syracuse-Hotels-Lanterne-Magiche-Ortigia.h18704044.Hotel-Information) ![Domus Mariae Albergo](https://images.trvl-media.com/lodging/3000000/2700000/2692900/2692832/121efcd2_y.jpg) ### Domus Mariae Albergo 10/10 Excellent "Awesome boutique hotel with cats and nuns—great views of the sea from some rooms. If you’re looking for a 3-star hotel in a superb location with very kind staff, you can’t go wrong here!" [](https://expedia.com/Syracuse-Hotels-Domus-Mariae-Albergo.h2692832.Hotel-Information) ![Maniace Boutique Hotel Ortigia UNA Esperienze](https://images.trvl-media.com/lodging/110000000/109090000/109087400/109087329/9c7a5849_y.jpg) ### Maniace Boutique Hotel Ortigia UNA Esperienze 10/10 Excellent "My husband and I had an amazing time. The location was ideal. Very close to shopping and restaurants but very quiet. Everyone there was so nice and helpful and the breakfast was perfect for a day of roaming around. We will stay here every time we visit Ortigia" [](https://expedia.com/Syracuse-Hotels-Maniace-Boutique-Hotel-Ortigia.h109087329.Hotel-Information) ![UNA HOTELS One Siracusa](https://images.trvl-media.com/lodging/1000000/900000/891100/891075/e153b7ef_y.jpg) ### UNA HOTELS One Siracusa 10/10 Excellent "Great room, breakfast, and staff. Adequate parking. Not too far from the historic district. Only issue we had is that the walls everywhere are painted black and lights were barely on, so it’s difficult to see where you are going. That’s the vibe, but older people like us may have a problem. " [](https://expedia.com/Syracuse-Hotels-UNAHOTELS-One-Siracusa.h891075.Hotel-Information) ![L'Approdo delle Sirene](https://images.trvl-media.com/lodging/3000000/2530000/2527300/2527263/fe44f2b7_y.jpg) ### L'Approdo delle Sirene 10/10 Excellent "We had such a lovely room, the private patio was gorgeous with many health plants and panoramic views of Ortigia. We could see the city on the right and the sea on the left. With the wooden table & chairs we had a lovely breakfast out there with a view and we were able to catch a beautiful sunset on our first night without having to leave. The staff made us feel comfortable and welcome, and the room was very clean & quiet. We would absolutely come back again." [](https://expedia.com/Syracuse-Hotels-LApprodo-Delle-Sirene.h2527263.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - More ways to book - [Hotels near Syracuse ](https://www.expedia.com/Syracuse-Airport-Hotels.0-aQIC-0.Travel-Guide-Filter-Hotels) - [Hotels near Temple of Apollo ](https://www.expedia.com/Temple-Of-Apollo-Hotels.0-l6103312-0.Travel-Guide-Filter-Hotels) - [Province of Syracuse Hotels ](https://www.expedia.com/Destinations-In-Province-Of-Syracuse.d6052967.Hotel-Destinations) - [All-Inclusive Resorts in Province of Syracuse ](https://www.expedia.com/Destinations-In-Province-Of-Syracuse-All-Inclusive-Hotel.0-0-d6052967-tAllinclusiveHotel.Hotel-Filter-Destinations) - [Family Hotels in Province of Syracuse ](https://www.expedia.com/Destinations-In-Province-Of-Syracuse-Family-Hotel.0-0-d6052967-tFamilyHotel.Hotel-Filter-Destinations) - [Resorts & Hotels with Spas in Province of Syracuse ](https://www.expedia.com/Destinations-In-Province-Of-Syracuse-Spa-Hotel.0-0-d6052967-tSpaHotel.Hotel-Filter-Destinations) - 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