Cheap Flights from Columbus (CMH) to St. Louis (CPS)

Popular airlines from John Glenn Columbus Intl. Airport (CMH) to St. Louis, MO (CPS-St. Louis Downtown)

    notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
    deals illustration

    Book smarter

    Save up to 30% on select hotels after you book a flight*
    trophy illustration

    Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Alternative airports near St. Louis

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Lambert-St. Louis Intl. STL. Cheapest option available. Average driving time to city center is 20 minutes. Flights from $413
STL
Lambert-St. Louis Intl.
Cheapest
Average driving time to city center20 min
Flights from $413

Frequently asked questions

How much does a flight from John Glenn Columbus Intl. Airport (CMH) to St. Louis Downtown Airport (CPS) cost?
Get a cheap one-way flight or cheap return flight from John Glenn Columbus Intl. Airport (CMH) to St. Louis Downtown Airport (CPS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from John Glenn Columbus Intl. Airport (CMH) to St. Louis Downtown Airport (CPS)?
is the most affordable month to fly from CMH to CPS. Timing your trip outside of the busy season is often the key to better flight prices.
What is the cheapest airline that flies from John Glenn Columbus Intl. Airport (CMH) to St. Louis Downtown Airport (CPS)?
Use the filter tool on Expedia to compare different airlines and find the cheapest carrier that'll take you from CMH to CPS. Then, sort your results by "Price (lowest to highest)" to snap up the best deal available.
How many flights per day from John Glenn Columbus Intl. Airport (CMH) to St. Louis Downtown Airport (CPS)?
There aren't any daily nonstop flights available from John Glenn Columbus Intl. Airport (CMH) to St. Louis Downtown Airport (CPS). But you can choose flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be soaring above the clouds in no time.
What day of the week has the most flights from CMH to CPS?
Typically you'll find the widest variety of flight choices on a Friday. Tuesdays are often the quietest.* But this can vary based on the time of year, carrier and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from John Glenn Columbus Intl. Airport (CMH) to St. Louis Downtown Airport (CPS)?
To reach St. Louis Downtown Airport (CPS) on time, choose a flight that takes off from John Glenn Columbus Intl. Airport (CMH) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for East St. Louis from John Glenn Columbus Intl. Airport (CMH)?
If you've booked a direct flight from John Glenn Columbus Intl. Airport (CMH) to East St. Louis, Lambert-St. Louis Intl. Airport (STL) is the only airport you can land at.
Is it cheaper to buy a plane ticket from John Glenn Columbus Intl. Airport (CMH) to St. Louis Downtown Airport (CPS) last-minute?
Holding off until just before your departure to book a ticket from CMH to CPS generally means paying more. While you may find some last-minute offers, they're not always guaranteed. Be flexible with your travel plans to boost your chances of snagging a bargain.
Is it cheaper to book a CMH to CPS flight and hotel package?
Opting for a CMH to CPS flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels all in one place. Select from our extensive range of accommodations and then add activities, car rentals and flights to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from John Glenn Columbus Intl. Airport (CMH) to St. Louis Downtown Airport (CPS)?
If you booked your CMH to CPS flight in the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the ticket type you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you want more information.

Travel information

Travel information

Origin airport
John Glenn Columbus Intl.
Destination airport
St. Louis Downtown
Distance
400 mi

Book with confidence

Book with confidence

Columbus to St. Louis Flights

The cheapest times to fly from Columbus to St. Louis

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Columbus to St. Louis are during the month of . You can find some of the cheapest flights from Columbus to St. Louis with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Columbus to St. Louis

Sunday is one of the best days to book for cheap flights from Columbus to St. Louis: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Columbus to St. Louis

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Columbus to St. Louis in 2025. You can also book with separate airlines for your outbound and return journeys, from one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Columbus to St. Louis flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Columbus to St. Louis airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Columbus to St. Louis Flights

Explore a world of travel with Expedia

Explore a world of travel with Expedia

*Available to One Key members.