$194 Cheap Flights from Panama City (ECP) to Key West (EYW)

View $194 flight on Sat, Jan 10, 2026Opens in a new window

Popular airlines from Northwest Florida Beaches Intl. Airport (ECP) to Key West Intl. Airport (EYW)

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Cheap Flights from Panama City to Key West (ECP-EYW)

Prices were available within the past 7 days and start at $194 for one-way flights and $307 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Jan 21 - Wed, Jan 28
ECP
Panama City
EYW
Key West
$307 Roundtrip, found 6 days ago
$307
Roundtrip
found 6 days ago
Select American Airlines flight, departing Wed, Jan 21 from Panama City to Key West, returning Wed, Jan 28, priced at $307 found 6 days ago
Delta
Tue, Dec 30 - Tue, Jan 13
ECP
Panama City
EYW
Key West
$307 Roundtrip, found 1 day ago
$307
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Dec 30 from Panama City to Key West, returning Tue, Jan 13, priced at $307 found 1 day ago
Delta
Tue, Dec 16 - Sun, Dec 21
ECP
Panama City
EYW
Key West
$317 Roundtrip, found 4 hours ago
$317
Roundtrip
found 4 hours ago
Select Delta flight, departing Tue, Dec 16 from Panama City to Key West, returning Sun, Dec 21, priced at $317 found 4 hours ago
Delta
Mon, Nov 24 - Tue, Dec 9
ECP
Panama City
EYW
Key West
$318 Roundtrip, found 1 day ago
$318
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Nov 24 from Panama City to Key West, returning Tue, Dec 9, priced at $318 found 1 day ago
Delta
Fri, Dec 5 - Wed, Dec 10
ECP
Panama City
EYW
Key West
$320 Roundtrip, found 1 day ago
$320
Roundtrip
found 1 day ago
Select Delta flight, departing Fri, Dec 5 from Panama City to Key West, returning Wed, Dec 10, priced at $320 found 1 day ago
Delta
Mon, Nov 24 - Wed, Dec 10
ECP
Panama City
EYW
Key West
$321 Roundtrip, found 1 day ago
$321
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Nov 24 from Panama City to Key West, returning Wed, Dec 10, priced at $321 found 1 day ago
American Airlines
Thu, Dec 18 - Sun, Dec 21
ECP
Panama City
EYW
Key West
$327 Roundtrip, found 4 hours ago
$327
Roundtrip
found 4 hours ago
Select American Airlines flight, departing Thu, Dec 18 from Panama City to Key West, returning Sun, Dec 21, priced at $327 found 4 hours ago
Delta
Sun, Dec 7 - Fri, Dec 19
ECP
Panama City
EYW
Key West
$328 Roundtrip, found 1 day ago
$328
Roundtrip
found 1 day ago
Select Delta flight, departing Sun, Dec 7 from Panama City to Key West, returning Fri, Dec 19, priced at $328 found 1 day ago
Delta
Mon, Nov 24 - Sat, Dec 6
ECP
Panama City
EYW
Key West
$329 Roundtrip, found 1 day ago
$329
Roundtrip
found 1 day ago
Select Delta flight, departing Mon, Nov 24 from Panama City to Key West, returning Sat, Dec 6, priced at $329 found 1 day ago
United
Tue, Mar 10 - Tue, Mar 17
ECP
Panama City
EYW
Key West
$969 Roundtrip, found 1 day ago
$969
Roundtrip
found 1 day ago
Select United flight, departing Tue, Mar 10 from Panama City to Key West, returning Tue, Mar 17, priced at $969 found 1 day ago

Find the cheapest month to fly from Panama City (ECP) to Key West (EYW)

September is typically the cheapest month to fly

From $296 - $536 per traveler.

Alternative airports near Key West

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Key West Intl. EYW. Cheapest and Closest option available. Average driving time to city center is 8 minutes. Flights from $359
EYW
Key West Intl.
CheapestClosest
Average driving time to city center8 min
Flights from $359

Frequently asked questions

How much does a flight from Northwest Florida Beaches Intl. Airport (ECP) to Key West Intl. Airport (EYW) cost?
Get a cheap one-way flight from $194 or cheap return flight from $307 from Northwest Florida Beaches Intl. Airport (ECP) to Key West Intl. Airport (EYW) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight deals on this route.
What is the cheapest month to fly from Northwest Florida Beaches Intl. Airport (ECP) to Key West Intl. Airport (EYW)?
The cheapest month to fly from ECP to EYW is January, when there's less demand. Off-peak months are typically when airlines offer better prices between these airports.
What is the cheapest airline that flies from Northwest Florida Beaches Intl. Airport (ECP) to Key West Intl. Airport (EYW)?
Expedia's filter tool lets you easily compare airlines, flight times and baggage options all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to find the carrier with the cheapest ECP to EYW flight.
How many flights per day from Northwest Florida Beaches Intl. Airport (ECP) to Key West Intl. Airport (EYW)?
There are no daily direct flights departing from Northwest Florida Beaches Intl. Airport (ECP) to Key West Intl. Airport (EYW). But you can opt for flights with layovers. Filter your search on Expedia to include one or two stops, and you'll be cruising above the clouds before you know it.
What day of the week has the most flights from ECP to EYW?
Generally you'll find the most flight options available on a Friday. Tuesdays are often the quietest.* However, this can change depending on the airline, season and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Northwest Florida Beaches Intl. Airport (ECP) to Key West Intl. Airport (EYW)?
To avoid possible delays on the Northwest Florida Beaches Intl. Airport (ECP) to Key West Intl. Airport (EYW) route, aim to travel before 3 PM. Flights after this time are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Northwest Florida Beaches Intl. Airport (ECP) to Key West Intl. Airport (EYW) last-minute?
Booking your flight from ECP to EYW shortly before your getaway is usually more expensive. However, if you're flexible with your schedule, you could bag a cheap last-minute fare.
Is it cheaper to book an ECP to EYW flight and hotel package?
Securing an ECP to EYW flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels all in one place. Choose from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Northwest Florida Beaches Intl. Airport (ECP) to Key West Intl. Airport (EYW)?
In most cases, you're able to cancel or reschedule your ECP to EYW flight. However, there may be additional fees, especially if your booking was made more than 24 hours ago. Check your itinerary for the airline's fees and rules on flight changes, or if you'd like more details, head to our Customer Service portal.

Travel information

Origin airport
Northwest Florida Beaches Intl.
Destination airport
Key West Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$306
Distance
471 mi

Book with confidence

Panama City to Key West Flights

The cheapest times to fly from Panama City to Key West

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Key West are during the month of January. You can find some of the cheapest flights from Panama City to Key West with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Panama City to Key West

Sunday is one of the best days to book for cheap flights from Panama City to Key West: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Panama City to Key West

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Key West in 2025. You can also book with separate airlines for your outbound and return journeys, from $194 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Key West flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Key West airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Panama City to Key West Flights

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*Available to One Key members.