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$300 Cheap Flights from Sioux Falls (FSD) to Buffalo (BUF)

View $300 flight on Fri, Jul 3, 2026Opens in a new window

Popular airlines from Sioux Falls Regional Airport (FSD) to Buffalo Niagara Intl. Airport (BUF)

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Cheap Flights from Sioux Falls to Buffalo (FSD-BUF)

Prices were available within the past 7 days and start at $300 for one-way flights and $311 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Sep 30 - Wed, Oct 7
FSD
Sioux Falls
BUF
Buffalo
$311 Roundtrip, found 1 day ago
$311
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Sep 30 from Sioux Falls to Buffalo, returning Wed, Oct 7, priced at $311 found 1 day ago
Delta
Sun, Sep 13 - Sat, Sep 19
FSD
Sioux Falls
BUF
Buffalo
$315 Roundtrip, found 1 day ago
$315
Roundtrip
found 1 day ago
Select Delta flight, departing Sun, Sep 13 from Sioux Falls to Buffalo, returning Sat, Sep 19, priced at $315 found 1 day ago
United
Tue, Jul 28 - Thu, Aug 13
FSD
Sioux Falls
BUF
Buffalo
$315 Roundtrip, found 1 day ago
$315
Roundtrip
found 1 day ago
Select United flight, departing Tue, Jul 28 from Sioux Falls to Buffalo, returning Thu, Aug 13, priced at $315 found 1 day ago
Delta
Wed, Sep 30 - Wed, Oct 7
FSD
Sioux Falls
BUF
Buffalo
$316 Roundtrip, found 1 day ago
$316
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Sep 30 from Sioux Falls to Buffalo, returning Wed, Oct 7, priced at $316 found 1 day ago
Delta
Thu, Jul 30 - Tue, Aug 4
FSD
Sioux Falls
BUF
Buffalo
$345 Roundtrip, found 4 days ago
$345
Roundtrip
found 4 days ago
Select Delta flight, departing Thu, Jul 30 from Sioux Falls to Buffalo, returning Tue, Aug 4, priced at $345 found 4 days ago
American Airlines
Wed, Sep 30 - Wed, Oct 7
FSD
Sioux Falls
BUF
Buffalo
$367 Roundtrip, found 1 day ago
$367
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Sep 30 from Sioux Falls to Buffalo, returning Wed, Oct 7, priced at $367 found 1 day ago
Delta
Thu, Jul 30 - Mon, Aug 3
FSD
Sioux Falls
BUF
Buffalo
$369 Roundtrip, found 5 hours ago
$369
Roundtrip
found 5 hours ago
Select Delta flight, departing Thu, Jul 30 from Sioux Falls to Buffalo, returning Mon, Aug 3, priced at $369 found 5 hours ago
American Airlines
Sat, Sep 5 - Thu, Sep 10
FSD
Sioux Falls
BUF
Buffalo
$371 Roundtrip, found 16 hours ago
$371
Roundtrip
found 16 hours ago
Select American Airlines flight, departing Sat, Sep 5 from Sioux Falls to Buffalo, returning Thu, Sep 10, priced at $371 found 16 hours ago
Delta
Sun, Sep 13 - Sat, Sep 19
FSD
Sioux Falls
BUF
Buffalo
$375 Roundtrip, found 1 day ago
$375
Roundtrip
found 1 day ago
Select Delta flight, departing Sun, Sep 13 from Sioux Falls to Buffalo, returning Sat, Sep 19, priced at $375 found 1 day ago
Delta
Wed, Sep 30 - Wed, Oct 7
FSD
Sioux Falls
BUF
Buffalo
$380 Roundtrip, found 1 day ago
$380
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Sep 30 from Sioux Falls to Buffalo, returning Wed, Oct 7, priced at $380 found 1 day ago

Alternative airports near Buffalo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Buffalo Niagara Intl. BUF. Cheapest and Closest option available. Average driving time to city center is 16 minutes. Flights from $723
BUF
Buffalo Niagara Intl.
CheapestClosest
Average driving time to city center16 min
Flights from $723

What you need to know for your flight from Sioux Falls Regional to Buffalo Niagara Intl.

Sioux Falls (FSD) to Buffalo (BUF) at a glance

Embark on your journey from Sioux Falls (FSD) to Buffalo (BUF) with a range of airlines offering convenient domestic flights. Evaluate options from various full-service carriers to discover the itinerary that aligns with your budget and travel schedule, all while preparing to explore the iconic sights and neighborhoods of Buffalo. Here, you’ll find essential information about flights departing from Sioux Falls Regional Airport (FSD) to Buffalo Niagara International Airport (BUF).

  • Fastest flight duration: around 3h 30m in-flight, plus roughly 1h 15m layover with one stop
  • Route distance: roughly 900 miles (1,450 km)
  • Flights per week: around 8 departures on average
  • Typical fares (one-way): economy tickets often range from $100–$420, depending on seasonality and how far ahead you book

Flights from Sioux Falls Regional Airport (FSD) to Buffalo Niagara International Airport (BUF)

According to recent traveler bookings, the top airlines flying from Sioux Falls to Buffalo are favored for their one-stop routes, often featuring layovers at O'Hare International Airport (ORD) with a 55-minute connection, Minneapolis-St. Paul International Airport (MSP) with a 1 hour and 30-minute stop, and Dallas-Fort Worth International Airport (DFW) with a 3 hour and 30-minute layover. These options allow you to balance price, total travel time, and cabin class to create the best travel itinerary for your needs.

  • United: This full-service airline provides a convenient one-stop option, with one-way ticket prices generally ranging from $130 to $415. United operates about 44% of the flights on this route, featuring an in-flight duration of 3 hours and 30 minutes, resulting in a total travel time of approximately 4 hours and 45 minutes, including layover time.
  • American Airlines: Offering a comprehensive one-stop service, American Airlines has one-way fares that typically fall between $100 and $455. Roughly 39% of departures for this route are operated by them, with an in-flight time of 3 hours and 30 minutes and an overall journey duration of about 4 hours and 45 minutes, including any layovers.
  • Delta: As a full-service carrier, Delta also provides one-stop services, with one-way fares generally ranging from $130 to $475. They account for around 17% of the departures on this route, with a flight time of 3 hours and 30 minutes and a total travel time of roughly 4 hours and 45 minutes, factoring in layover time.

Alternative route from Sioux Falls (FSD) to Buffalo (BUF)

  • Sioux Falls to Rochester (FSD-ROC): Greater Rochester International Airport (ROC) is located approximately 56 miles from Buffalo Niagara International Airport (BUF). One-way economy tickets on this route generally vary between $120 and $475, influenced by the time of year and how far in advance you book. This route typically features one-stop flights, with common layover points at O'Hare International Airport (ORD) and Hartsfield-Jackson Atlanta International Airport (ATL). Major airlines servicing this route include United and American Airlines. Additionally, premium seating options are offered on this flight.

How to find the best prices for flights from Sioux Falls (FSD) to Buffalo (BUF)

Getting some of the best deals on flights from Sioux Falls to Buffalo is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually found when booking 2-8 weeks in advance, which coincides with when most travelers make their reservations. Afternoon departures (12pm-6pm) tend to offer lower prices, while morning flights (5am-12pm) are more popular. Additionally, flying on Wednesday generally provides cheaper prices, even though Friday is the busiest travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Buffalo Niagara International Airport from Sioux Falls Regional Airport

Buffalo welcomes travelers from Sioux Falls with a range of transport options based on price, convenience, and proximity. Here's how to reach Buffalo efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Buffalo, with private rides that can be arranged in advance.
  • Car rental: Renting a car from Buffalo Niagara International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Buffalo Niagara International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From Buffalo Niagara International Airport, Buffalo-Depew Station, a train station, is located about 2.6 miles away by car, while University Station, a metro station, is situated approximately 6.5 miles from the airport, also most conveniently accessed by car.

Frequently asked questions

How much does a flight from Sioux Falls, SD (FSD-Sioux Falls Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.) cost?
You can find cheap one-way flights from $300 and cheap return flights from $311 Sioux Falls, SD (FSD-Sioux Falls Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.) with Expedia. One-way flights usually range from $305 to $766, and return flights typically cost between $455 and $1680. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Sioux Falls, SD (FSD-Sioux Falls Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Sioux Falls, SD (FSD-Sioux Falls Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The cheapest month to fly from FSD to BUF is September when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Sioux Falls, SD (FSD-Sioux Falls Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Enter FSD to BUF and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Sioux Falls, SD (FSD-Sioux Falls Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
American Airlines is one of the cheapest airlines offering connecting flights from Sioux Falls Regional (FSD) to Buffalo Niagara Intl. (BUF) with round-trip tickets starting from around $258 with a layover in O'Hare Intl. (ORD). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Sioux Falls, SD (FSD-Sioux Falls Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
To find a cheap flight from Sioux Falls, SD (FSD-Sioux Falls Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Sioux Falls, SD (FSD-Sioux Falls Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Sioux Falls, SD (FSD-Sioux Falls Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The earliest flight from Sioux Falls Regional Airport (FSD) to Buffalo Niagara International Airport (BUF) typically departs at around 5:00 AM, operated by Delta. This is a seasonal service active in April. An early flight can help you get a jump on your day in Buffalo. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Sioux Falls, SD (FSD-Sioux Falls Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The most popular departure times for flights from Sioux Falls Regional (FSD) to Buffalo Niagara Intl. (BUF) are in the early morning, from 6am to 9am. About 27% of passengers prefer this time window. Many major carriers, including United Airlines and American Airlines, offer flights during this window. This timing works well as it allows you to arrive in Buffalo with plenty of time to explore.
How long does it take to fly from Sioux Falls, SD (FSD-Sioux Falls Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Flying from FSD to BUF with a connection usually takes about 4 hours 30 minutes, traveling roughly 905 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Sioux Falls, SD (FSD-Sioux Falls Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
First class is available on flights from FSD to BUF. First class cabins are available on:

  • Delta Air Lines
  • United Airlines
  • American Airlines

How do I earn miles on a Sioux Falls, SD (FSD-Sioux Falls Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight with Expedia?
It's easy to earn miles on a Sioux Falls, SD (FSD-Sioux Falls Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Buffalo from Sioux Falls Regional (FSD)?
If you're planning to travel to Buffalo from Sioux Falls Regional (FSD), you can fly into Buffalo Niagara Intl. (BUF) Some flights may connect through major hubs like Minneapolis - St. Paul Intl. (MSP), O'Hare Intl. (ORD), Denver Intl. (DEN) before reaching Buffalo. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Sioux Falls, SD (FSD-Sioux Falls Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.) at the last minute?
Typically, booking a last minute flight from Sioux Falls, SD (FSD-Sioux Falls Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Sioux Falls, SD (FSD-Sioux Falls Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight and hotel package?
Securing a Sioux Falls, SD (FSD-Sioux Falls Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.) Buffalo Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Sioux Falls, SD (FSD-Sioux Falls Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
If you booked your Sioux Falls, SD (FSD-Sioux Falls Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Sioux Falls Regional
Destination airport
Buffalo Niagara Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$310
Distance
905 mi

Book with confidence

Sioux Falls to Buffalo Flights

The cheapest times to fly from Sioux Falls to Buffalo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Sioux Falls to Buffalo are during the month of September. You can find some of the cheapest flights from Sioux Falls to Buffalo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Sioux Falls to Buffalo

Sunday is one of the best days to book for cheap flights from Sioux Falls to Buffalo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Sioux Falls to Buffalo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Sioux Falls to Buffalo in 2026. You can also book with separate airlines for your outbound and return journeys, from $300 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Sioux Falls to Buffalo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Sioux Falls to Buffalo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Sioux Falls to Buffalo Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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