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$152 Cheap Flights from St. Louis (STL) to Buffalo (BUF)

View $152 flight on Thu, Nov 26, 2026Opens in a new window

Popular airlines from St. Louis Lambert Intl. Airport (STL) to Buffalo Niagara Intl. Airport (BUF)

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Cheap Flights from St. Louis to Buffalo (STL-BUF)

Prices were available within the past 7 days and start at $152 for one-way flights and $254 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Thu, Aug 13 - Sat, Aug 15
STL
St. Louis
BUF
Buffalo
$254 Roundtrip, found 12 hours ago
$254
Roundtrip
found 12 hours ago
Select Frontier Airlines flight, departing Thu, Aug 13 from St. Louis to Buffalo, returning Sat, Aug 15, priced at $254 found 12 hours ago
Frontier Airlines
Sat, Aug 22 - Wed, Aug 26
STL
St. Louis
BUF
Buffalo
$258 Roundtrip, found 5 hours ago
$258
Roundtrip
found 5 hours ago
Select Frontier Airlines flight, departing Sat, Aug 22 from St. Louis to Buffalo, returning Wed, Aug 26, priced at $258 found 5 hours ago
Frontier Airlines
Sat, Aug 22 - Mon, Aug 31
STL
St. Louis
BUF
Buffalo
$260 Roundtrip, found 5 hours ago
$260
Roundtrip
found 5 hours ago
Select Frontier Airlines flight, departing Sat, Aug 22 from St. Louis to Buffalo, returning Mon, Aug 31, priced at $260 found 5 hours ago
Frontier Airlines
Mon, Aug 17 - Sun, Aug 23
STL
St. Louis
BUF
Buffalo
$261 Roundtrip, found 12 hours ago
$261
Roundtrip
found 12 hours ago
Select Frontier Airlines flight, departing Mon, Aug 17 from St. Louis to Buffalo, returning Sun, Aug 23, priced at $261 found 12 hours ago
Frontier Airlines
Sat, Aug 22 - Sun, Aug 30
STL
St. Louis
BUF
Buffalo
$264 Roundtrip, found 5 hours ago
$264
Roundtrip
found 5 hours ago
Select Frontier Airlines flight, departing Sat, Aug 22 from St. Louis to Buffalo, returning Sun, Aug 30, priced at $264 found 5 hours ago
Frontier Airlines
Sun, Aug 30 - Sun, Sep 13
STL
St. Louis
BUF
Buffalo
$268 Roundtrip, found 1 day ago
$268
Roundtrip
found 1 day ago
Select Frontier Airlines flight, departing Sun, Aug 30 from St. Louis to Buffalo, returning Sun, Sep 13, priced at $268 found 1 day ago
Southwest Airlines
Thu, Aug 20 - Mon, Aug 24
STL
St. Louis
BUF
Buffalo
$274 Roundtrip, found 20 hours ago
$274
Roundtrip
found 20 hours ago
Select Southwest Airlines flight, departing Thu, Aug 20 from St. Louis to Buffalo, returning Mon, Aug 24, priced at $274 found 20 hours ago
Delta
Wed, Aug 12 - Thu, Aug 13
STL
St. Louis
BUF
Buffalo
$290 Roundtrip, found 3 days ago
$290
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, Aug 12 from St. Louis to Buffalo, returning Thu, Aug 13, priced at $290 found 3 days ago
United
Tue, Aug 11 - Wed, Aug 12
STL
St. Louis
BUF
Buffalo
$298 Roundtrip, found 2 days ago
$298
Roundtrip
found 2 days ago
Select United flight, departing Tue, Aug 11 from St. Louis to Buffalo, returning Wed, Aug 12, priced at $298 found 2 days ago
American Airlines
Thu, Sep 3 - Sun, Sep 6
STL
St. Louis
BUF
Buffalo
$301 Roundtrip, found 10 hours ago
$301
Roundtrip
found 10 hours ago
Select American Airlines flight, departing Thu, Sep 3 from St. Louis to Buffalo, returning Sun, Sep 6, priced at $301 found 10 hours ago

Alternative airports near Buffalo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Buffalo Niagara Intl. BUF. Cheapest and Closest option available. Average driving time to city center is 16 minutes. Flights from $414
BUF
Buffalo Niagara Intl.
CheapestClosest
Average driving time to city center16 min
Flights from $414

What you need to know for your flight from Lambert-St. Louis Intl. to Buffalo Niagara Intl.

St. Louis (STL) to Buffalo (BUF) at a glance

Travel between St. Louis (STL) and Buffalo (BUF) with a selection of airlines operating on this domestic short-haul route. Explore options from both full-service and budget carriers to discover the itinerary that aligns with your budget, schedule, and travel preferences as you experience Buffalo's renowned attractions and neighborhoods. Get all the essential information for flights departing from Lambert-St. Louis International Airport (STL) to Buffalo Niagara International Airport (BUF).

  • Fastest flight duration: around 3h 15m in-flight, plus roughly 1h 15m layover with one stop
  • Route distance: roughly 700 miles (1,130 km)
  • Flights per week: around 11 departures on average
  • Typical fares (one-way): economy tickets often range from $110–$380, depending on seasonality and how far ahead you book

Flights from Lambert-St. Louis International Airport (STL) to Buffalo Niagara International Airport (BUF)

According to recent traveler bookings, the top airlines flying from St. Louis to Buffalo are often selected for their one-stop services. Common layover options include O'Hare International Airport, ORD (approximately 1-hour layover), Detroit Metropolitan Wayne County Airport, DTW (around 1 hour and 15 minutes), and Midway International Airport, MDW (also about 1 hour and 15 minutes). These choices allow you to customize your travel experience by balancing price, total travel time, and cabin class to find the ideal itinerary.

  • American Airlines: As a premier full-service airline, American Airlines provides one-stop flights, typically charging one-way fares between $110 and $380. It represents about 39% of departures on this route, featuring an in-flight duration of 3 hours 15 minutes and a total travel time of approximately 4 hours 30 minutes, including layover time.
  • Delta: This full-service airline offers one-stop service with one-way fares generally ranging from $120 to $400. Delta accounts for around 27% of the departures on this route, with an in-flight time of 3 hours 15 minutes and an overall journey time of about 4 hours 30 minutes, including the layover.
  • Southwest Airlines: A budget-friendly option, Southwest Airlines provides one-stop service with one-way fares that usually fall between $110 and $390. This airline handles roughly 23% of departures along this route, with a flight time of 3 hours 15 minutes and a total travel duration of around 4 hours 30 minutes, factoring in the layover.
  • United: United, a full-service airline, offers one-stop service with one-way ticket prices typically ranging from $145 to $390. It constitutes about 11% of the departures on this route, with an in-flight duration of 3 hours 15 minutes and a complete travel time of roughly 4 hours 30 minutes, including any layover.

Travelers have the option to enhance their journey from St. Louis to Buffalo with an upgrade. American Airlines features first-class service, while Delta offers both first-class and premium economy seating.

Best time to fly from St. Louis (STL) to Buffalo (BUF)

The most popular months for travelers flying from St. Louis to Buffalo are April, July, and September, when peak temperatures in Buffalo reach up to 72°F in July. If you prefer quieter travel, consider May, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 57.7°F. For better deals, August usually offers the lowest average one-way fare around $181. Flight availability peaks in October, with approximately 14 flights per week, making it easier to find convenient departure times. January has the fewest flights, with approximately 8 flights per week.

  • Cheapest time to fly: August usually offers good deals with average one-way fare around $181, roughly 18% cheaper than the yearly average.
  • More budget-friendly months to fly: July, September, and May typically offer average one-way fares of around $189.
  • Most flight options: October has the highest number of flights from St. Louis to Buffalo, with approximately 14 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January25.5°F (-3.6°C)Average8$278
February26.1°F (-3.3°C)Moderately Low11$231
March34.3°F (1.3°C)Average9$259
April45.0°F (7.2°C)Moderately High13$251
May57.7°F (14.3°C)Moderately Low11$193
June66.0°F (18.9°C)Average10$208
July72.0°F (22.2°C)Moderately High13$185
August70.7°F (21.5°C)Average12$181
September64.6°F (18.1°C)Moderately High11$189
October53.2°F (11.8°C)Average14$217
November41.4°F (5.2°C)Average11$220
December33.1°F (0.6°C)Moderately Low12$251

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative route from St. Louis (STL) to Buffalo (BUF)

  • St. Louis to Rochester (STL-ROC): Greater Rochester International Airport (ROC) is located approximately 56 miles from Buffalo Niagara International Airport (BUF). One-way economy prices for this journey generally vary between $125 and $380, influenced by the season and timing of booking. This route is commonly offered with both non-stop and one-stop flight options, with popular layover points at O'Hare International Airport (ORD) and Detroit Metropolitan Wayne County Airport (DTW). Major airlines servicing this route include American Airlines and Delta. Additionally, first-class service is available for travelers.

How to find the best prices for flights from St. Louis (STL) to Buffalo (BUF)

Getting some of the best deals on flights from St. Louis to Buffalo is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually available when booking at least two months in advance, although most travelers tend to book two to eight weeks ahead. Afternoon departures from 12 PM to 6 PM often provide lower prices, while morning flights from 5 AM to 12 PM are the most popular. Additionally, flying on Saturday generally offers better rates, although Friday remains the busiest travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Buffalo Niagara International Airport from Lambert-St. Louis International Airport

Buffalo welcomes travelers from St. Louis with a range of transport options based on price, convenience, and proximity. Here's how to reach Buffalo efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Buffalo, with private rides that can be arranged in advance.
  • Car rental: Renting a car from Buffalo Niagara International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Buffalo Niagara International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From Buffalo Niagara International Airport, Buffalo-Depew Station, a train station, is located about 2.6 miles away by car, while University Station, a metro station, is situated approximately 6.5 miles away by car, providing convenient transport options for travelers.

Frequently asked questions

How much does a flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) cost?
You can find cheap one-way flights from $152 and cheap return flights from $254 St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) with Expedia. One-way flights usually range from $126 to $712, and return flights typically cost between $351 and $1042. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The cheapest month to fly from STL to BUF is August when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Enter STL to BUF and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Frontier Airlines is one of the cheapest airlines offering connecting flights from St. Louis (STL) to Buffalo (BUF), with round-trip tickets starting from around $433. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
To find a cheap flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The earliest flight from St. Louis, Missouri (STL-Lambert-St. Louis Intl.) to Buffalo, New York (BUF-Buffalo Niagara Intl.) typically departs at around 5:00 AM, operated by American Airlines. This seasonal service is available in January, November, and December, perfect for those looking to start their journey early. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The most popular departure times for flights from St. Louis, MO (STL) to Buffalo, NY (BUF) are in the early morning, from 6am to 9am. About 34% of passengers prefer this time window. Many major carriers, including American Airlines, Southwest Airlines, and United Airlines, offer flights during this window. This timing is favored because it allows you to arrive in Buffalo with a full day ahead of you.
How long does it take to fly from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Flights from STL to BUF with one stop typically take around 4 hours 50 minutes, covering approximately 673 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
You can fly first class between STL and BUF. First class cabins are available on:

  • Delta Air Lines
  • United Airlines
  • American Airlines

How do I earn miles on a St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight with Expedia?
It's easy to earn miles on a St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Buffalo from Lambert-St. Louis Intl. (STL)?
From Lambert-St. Louis Intl. (STL), you can fly into Buffalo Niagara Intl. (BUF) to reach Buffalo. Some flights may connect through major hubs like O'Hare Intl. (ORD), Charlotte-Douglas Intl. (CLT), Midway Intl. (MDW) before reaching Buffalo. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) at the last minute?
Typically, booking a last minute flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight and hotel package?
Securing a St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) Buffalo Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
If you booked your St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Lambert-St. Louis Intl.
Destination airport
Buffalo Niagara Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Roundtrip price
$254
Distance
672 mi

Book with confidence

St. Louis to Buffalo Flights

The cheapest times to fly from St. Louis to Buffalo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from St. Louis to Buffalo are during the month of August. You can find some of the cheapest flights from St. Louis to Buffalo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from St. Louis to Buffalo

Sunday is one of the best days to book for cheap flights from St. Louis to Buffalo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from St. Louis to Buffalo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from St. Louis to Buffalo in 2026. You can also book with separate airlines for your outbound and return journeys, from $152 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap St. Louis to Buffalo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your St. Louis to Buffalo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

St. Louis to Buffalo Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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