$119 Cheap Flights from St. Louis (STL) to Buffalo (BUF)

View $119 flight on Wed, Apr 22, 2026Opens in a new window

Popular airlines from St. Louis Lambert Intl. Airport (STL) to Buffalo Niagara Intl. Airport (BUF)

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 30% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our OneKeyCash
    Learn about One Key

Cheap Flights from St. Louis to Buffalo (STL-BUF)

Prices were available within the past 7 days and start at $119 for one-way flights and $170 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frontier Airlines
Thu, Apr 23 - Sat, May 9
STL
St. Louis
BUF
Buffalo
$170 Roundtrip, found 16 hours ago
$170
Roundtrip
found 16 hours ago
Select Frontier Airlines flight, departing Thu, Apr 23 from St. Louis to Buffalo, returning Sat, May 9, priced at $170 found 16 hours ago
Frontier Airlines
Thu, Apr 23 - Thu, May 7
STL
St. Louis
BUF
Buffalo
$191 Roundtrip, found 16 hours ago
$191
Roundtrip
found 16 hours ago
Select Frontier Airlines flight, departing Thu, Apr 23 from St. Louis to Buffalo, returning Thu, May 7, priced at $191 found 16 hours ago
Frontier Airlines
Thu, Mar 26 - Fri, Apr 10
STL
St. Louis
BUF
Buffalo
$199 Roundtrip, found 16 hours ago
$199
Roundtrip
found 16 hours ago
Select Frontier Airlines flight, departing Thu, Mar 26 from St. Louis to Buffalo, returning Fri, Apr 10, priced at $199 found 16 hours ago
Frontier Airlines
Sun, Mar 29 - Fri, Apr 17
STL
St. Louis
BUF
Buffalo
$205 Roundtrip, found 16 hours ago
$205
Roundtrip
found 16 hours ago
Select Frontier Airlines flight, departing Sun, Mar 29 from St. Louis to Buffalo, returning Fri, Apr 17, priced at $205 found 16 hours ago
Frontier Airlines
Wed, May 6 - Mon, May 18
STL
St. Louis
BUF
Buffalo
$212 Roundtrip, found 5 days ago
$212
Roundtrip
found 5 days ago
Select Frontier Airlines flight, departing Wed, May 6 from St. Louis to Buffalo, returning Mon, May 18, priced at $212 found 5 days ago
Frontier Airlines
Sat, Mar 28 - Wed, Apr 8
STL
St. Louis
BUF
Buffalo
$216 Roundtrip, found 4 days ago
$216
Roundtrip
found 4 days ago
Select Frontier Airlines flight, departing Sat, Mar 28 from St. Louis to Buffalo, returning Wed, Apr 8, priced at $216 found 4 days ago
American Airlines
Tue, Mar 31 - Fri, Apr 10
STL
St. Louis
BUF
Buffalo
$219 Roundtrip, found 5 days ago
$219
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, Mar 31 from St. Louis to Buffalo, returning Fri, Apr 10, priced at $219 found 5 days ago
Delta
Tue, Apr 7 - Wed, Apr 15
STL
St. Louis
BUF
Buffalo
$237 Roundtrip, found 3 hours ago
$237
Roundtrip
found 3 hours ago
Select Delta flight, departing Tue, Apr 7 from St. Louis to Buffalo, returning Wed, Apr 15, priced at $237 found 3 hours ago
Southwest Airlines
Tue, Apr 7 - Tue, Apr 14
STL
St. Louis
BUF
Buffalo
$237 Roundtrip, found 3 hours ago
$237
Roundtrip
found 3 hours ago
Select Southwest Airlines flight, departing Tue, Apr 7 from St. Louis to Buffalo, returning Tue, Apr 14, priced at $237 found 3 hours ago
United
Tue, Apr 7 - Tue, Apr 14
STL
St. Louis
BUF
Buffalo
$250 Roundtrip, found 3 hours ago
$250
Roundtrip
found 3 hours ago
Select United flight, departing Tue, Apr 7 from St. Louis to Buffalo, returning Tue, Apr 14, priced at $250 found 3 hours ago

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.
Book now

Alternative airports near Buffalo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Buffalo Niagara Intl. BUF. Cheapest and Closest option available. Average driving time to city center is 16 minutes. Flights from $280
BUF
Buffalo Niagara Intl.
CheapestClosest
Average driving time to city center16 min
Flights from $280

Find the cheapest month to fly from St. Louis (STL) to Buffalo (BUF)

August is typically the cheapest month to fly

From $165 - $471 per traveler.

Frequently asked questions

How much does a flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) cost?
You can find cheap one-way flights from $119 and cheap return flights from $170 St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) with Expedia. One-way flights usually range from $126 to $712, and return flights typically cost between $351 and $1042. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The cheapest month to fly from STL to BUF is April when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Enter STL to BUF and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Frontier Airlines is one of the cheapest airlines offering connecting flights from St. Louis (STL) to Buffalo (BUF), with round-trip tickets starting from around $433. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
To find a cheap flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The earliest flight from St. Louis, Missouri (STL-Lambert-St. Louis Intl.) to Buffalo, New York (BUF-Buffalo Niagara Intl.) typically departs at around 5:00 AM, operated by American Airlines. This seasonal service is available in January, November, and December, perfect for those looking to start their journey early. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The most popular departure times for flights from St. Louis, MO (STL) to Buffalo, NY (BUF) are in the early morning, from 6am to 9am. About 34% of passengers prefer this time window. Many major carriers, including American Airlines, Southwest Airlines, and United Airlines, offer flights during this window. This timing is favored because it allows you to arrive in Buffalo with a full day ahead of you.
How long does it take to fly from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Flights from STL to BUF with one stop typically take around 4 hours 50 minutes, covering approximately 673 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
You can fly first class between STL and BUF. First class cabins are available on:

  • Delta Air Lines
  • United Airlines
  • American Airlines

How do I earn miles on a St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight with Expedia?
It's easy to earn miles on a St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Buffalo from Lambert-St. Louis Intl. (STL)?
From Lambert-St. Louis Intl. (STL), you can fly into Buffalo Niagara Intl. (BUF) to reach Buffalo. Some flights may connect through major hubs like O'Hare Intl. (ORD), Charlotte-Douglas Intl. (CLT), Midway Intl. (MDW) before reaching Buffalo. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) at the last minute?
Typically, booking a last minute flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight and hotel package?
Securing a St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) Buffalo Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
If you booked your St. Louis, MO (STL-Lambert-St. Louis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Lambert-St. Louis Intl.
Destination airport
Buffalo Niagara Intl.
Airlines serving
American Airlines, Delta, Frontier Airlines, Southwest Airlines, United
Roundtrip price
$170
Distance
672 mi

Book with confidence

St. Louis to Buffalo Flights

The cheapest times to fly from St. Louis to Buffalo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from St. Louis to Buffalo are during the month of April. You can find some of the cheapest flights from St. Louis to Buffalo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from St. Louis to Buffalo

Sunday is one of the best days to book for cheap flights from St. Louis to Buffalo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from St. Louis to Buffalo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from St. Louis to Buffalo in 2026. You can also book with separate airlines for your outbound and return journeys, from $119 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap St. Louis to Buffalo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your St. Louis to Buffalo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

St. Louis to Buffalo Flights

*Flight schedules are subject to change.

Explore a world of travel with Expedia

*Available to One Key members.