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$155 Cheap Flights from Greenville (GSP) to Buffalo (BUF)

View $155 flight on Fri, Oct 30, 2026Opens in a new window

Popular airlines from Greenville-Spartanburg Intl. Airport (GSP) to Buffalo Niagara Intl. Airport (BUF)

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Cheap Flights from Greenville to Buffalo (GSP-BUF)

Prices were available within the past 7 days and start at $155 for one-way flights and $309 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sat, Sep 5 - Sun, Sep 6
GSP
Greenville
BUF
Buffalo
$309 Roundtrip, found 8 hours ago
$309
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Sat, Sep 5 from Greenville to Buffalo, returning Sun, Sep 6, priced at $309 found 8 hours ago
United
Sat, Sep 5 - Sun, Sep 6
GSP
Greenville
BUF
Buffalo
$309 Roundtrip, found 8 hours ago
$309
Roundtrip
found 8 hours ago
Select United flight, departing Sat, Sep 5 from Greenville to Buffalo, returning Sun, Sep 6, priced at $309 found 8 hours ago
United
Sat, Sep 5 - Sun, Sep 6
GSP
Greenville
BUF
Buffalo
$314 Roundtrip, found 8 hours ago
$314
Roundtrip
found 8 hours ago
Select United flight, departing Sat, Sep 5 from Greenville to Buffalo, returning Sun, Sep 6, priced at $314 found 8 hours ago
United
Sat, Sep 5 - Sun, Sep 6
GSP
Greenville
BUF
Buffalo
$319 Roundtrip, found 8 hours ago
$319
Roundtrip
found 8 hours ago
Select United flight, departing Sat, Sep 5 from Greenville to Buffalo, returning Sun, Sep 6, priced at $319 found 8 hours ago
American Airlines
Sat, Sep 5 - Sun, Sep 6
GSP
Greenville
BUF
Buffalo
$321 Roundtrip, found 8 hours ago
$321
Roundtrip
found 8 hours ago
Select American Airlines flight, departing Sat, Sep 5 from Greenville to Buffalo, returning Sun, Sep 6, priced at $321 found 8 hours ago
Delta
Sat, Aug 29 - Sat, Sep 5
GSP
Greenville
BUF
Buffalo
$322 Roundtrip, found 1 day ago
$322
Roundtrip
found 1 day ago
Select Delta flight, departing Sat, Aug 29 from Greenville to Buffalo, returning Sat, Sep 5, priced at $322 found 1 day ago
American Airlines
Sat, Aug 29 - Sat, Sep 5
GSP
Greenville
BUF
Buffalo
$324 Roundtrip, found 1 day ago
$324
Roundtrip
found 1 day ago
Select American Airlines flight, departing Sat, Aug 29 from Greenville to Buffalo, returning Sat, Sep 5, priced at $324 found 1 day ago
American Airlines
Sat, Sep 5 - Thu, Sep 10
GSP
Greenville
BUF
Buffalo
$328 Roundtrip, found 19 hours ago
$328
Roundtrip
found 19 hours ago
Select American Airlines flight, departing Sat, Sep 5 from Greenville to Buffalo, returning Thu, Sep 10, priced at $328 found 19 hours ago
United
Sat, Sep 5 - Thu, Sep 10
GSP
Greenville
BUF
Buffalo
$329 Roundtrip, found 19 hours ago
$329
Roundtrip
found 19 hours ago
Select United flight, departing Sat, Sep 5 from Greenville to Buffalo, returning Thu, Sep 10, priced at $329 found 19 hours ago
Southwest Airlines
Thu, Oct 15 - Tue, Oct 20
GSP
Greenville
BUF
Buffalo
$335 Roundtrip, found 1 day ago
$335
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Thu, Oct 15 from Greenville to Buffalo, returning Tue, Oct 20, priced at $335 found 1 day ago

Alternative airports near Buffalo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Buffalo Niagara Intl. BUF. Cheapest and Closest option available. Average driving time to city center is 16 minutes. Flights from $477
BUF
Buffalo Niagara Intl.
CheapestClosest
Average driving time to city center16 min
Flights from $477

Find the cheapest month to fly from Greenville (GSP) to Buffalo (BUF)

January is typically the cheapest month to fly

From $222 - $511 per traveler.

What you need to know for your flight from Greenville-Spartanburg Intl. to Buffalo Niagara Intl.

Greenville (GSP) to Buffalo (BUF) at a glance

Travel from Greenville (GSP) to Buffalo (BUF) with a range of airlines offering convenient options on this domestic short-haul route. Explore various choices, from low-cost to full-service carriers, to discover the best Greenville to Buffalo airfare that fits your budget and schedule. With weekly flights from Greenville-Spartanburg International Airport (GSP) to Buffalo Niagara International Airport (BUF), you're sure to find the perfect itinerary to experience the iconic sights and neighborhoods of Buffalo.

  • Fastest (typical) flight duration: around 3 hours in-flight, plus roughly 1h 15m layover with one stop
  • Route distance: roughly 600 miles (970 km)
  • Flights per week: around 10 departures on average
  • Typical fares (one-way): economy tickets often range from $110–$370, depending on seasonality and how far ahead you book

Flights from Greenville-Spartanburg International Airport (GSP) to Buffalo Niagara International Airport (BUF)

Based on recent traveler bookings, here are the top airlines flying from Greenville to Buffalo, mainly selected for their one-stop services. Common layover spots include Charlotte-Douglas International Airport (CLT) with a layover of about 1 hour and 15 minutes, Hartsfield-Jackson Atlanta International Airport (ATL) with a 1 hour and 30 minutes layover, and Baltimore Washington International Thurgood Marshall Airport (BWI) with a 1-hour layover. These options provide the flexibility to balance price, total travel time, and cabin class for your ideal itinerary.

  • American Airlines: This full-service airline provides one-stop flights, holding about 45% of departures on this route. One-way ticket prices usually fall between $115 and $380, with an in-flight duration of 3 hours and a total travel time of around 4 hours and 15 minutes, including layovers.
  • Delta: As another full-service option, Delta accounts for approximately 31% of departures on this route. Their one-stop fares generally range from $110 to $345, featuring an in-air time of 3 hours and a total journey time of about 4 hours and 15 minutes, factoring in layovers.
  • Southwest Airlines: Known as a low-cost carrier, Southwest provides one-stop services and represents roughly 14% of departures on this route. One-way fares are typically priced between $115 and $380, with a flight duration of 3 hours and a total travel time of around 4 hours and 15 minutes, including layovers.
  • United: This full-service airline accounts for about 10% of departures on this route, offering one-stop options. Their one-way fares typically range from $115 to $325, with 3 hours of flight time and an overall journey duration of about 4 hours and 15 minutes, including layovers.

Travelers flying from Greenville to Buffalo can enhance their experience by upgrading to first class or premium economy class service, both offered by Delta on this route.

Best time to fly from Greenville (GSP) to Buffalo (BUF)

The most popular months for travelers flying from Greenville to Buffalo are April, May, and July, when peak temperatures in Buffalo reach up to 72°F in July. If you prefer quieter travel, consider February, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 26.1°F. For better deals, September usually offers the lowest average one-way fare around $188. Flight availability peaks in May, July, October, and November, with approximately 12 flights per week, making it easier to find convenient departure times. March and December have the fewest flights, with approximately 8 flights per week.

  • Cheapest time to fly: September usually offers good deals with average one-way fare around $188, roughly 12% cheaper than the yearly average.
  • More budget-friendly months to fly: August, February, and July typically offer average one-way fares of around $200.
  • Most flight options: May, July, October, and November have the highest number of flights from Greenville to Buffalo, with approximately 12 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January25.5°F (-3.6°C)Moderately Low9$235
February26.1°F (-3.3°C)Moderately Low9$202
March34.3°F (1.3°C)Average8$236
April45.0°F (7.2°C)Moderately High9$228
May57.7°F (14.3°C)Moderately High12$204
June66.0°F (18.9°C)Average10$204
July72.0°F (22.2°C)Moderately High12$202
August70.7°F (21.5°C)Average10$199
September64.6°F (18.1°C)Average11$188
October53.2°F (11.8°C)Average12$209
November41.4°F (5.2°C)Moderately Low12$225
December33.1°F (0.6°C)Average8$239

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative route from Greenville (GSP) to Buffalo (BUF)

  • Greenville to Rochester (GSP-ROC): Greater Rochester International Airport (ROC) is located approximately 56 miles from Buffalo Niagara International Airport (BUF). On this route, one-way economy fares generally fall between $110 and $390, influenced by the season and when you book. Travelers typically find one-stop options, with common layover points at Philadelphia International Airport (PHL) and Ronald Reagan Washington National Airport (DCA). Major airlines servicing this route include American Airlines and Delta, and passengers can also opt for first-class service.

How to find the best prices for flights from Greenville (GSP) to Buffalo (BUF)

Getting some of the best deals on flights from Greenville to Buffalo is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually found when booking 2-8 weeks in advance, which coincides with when most travelers make their reservations. Morning departures between 5 AM and 12 PM tend to offer lower prices and are also the most popular times to fly. Additionally, flying on Wednesday generally provides cheaper options, while Thursday is the busiest travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Buffalo Niagara International Airport from Greenville-Spartanburg International Airport

Buffalo welcomes travelers from Greenville with a range of transport options based on price, convenience, and proximity. For departures, Greenville-Spartanburg International Airport is roughly a 20-minute drive (covering about 16 miles) from central Greenville. Here's how to reach Buffalo efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Buffalo, with private rides that can be arranged in advance.
  • Car rental: Renting a car from Buffalo Niagara International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Buffalo Niagara International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From Buffalo Niagara International Airport, Buffalo-Depew Station, a train station, is located about 2.6 miles away by car, while University Station, a metro station, is situated approximately 6.5 miles away by car, providing convenient access to public transport options.

Frequently asked questions

How much does a flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) cost?
You can find cheap one-way flights from $155 and cheap return flights from $309 Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) with Expedia. One-way flights usually range from $162 to $644, and return flights typically cost between $323 and $1047. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The cheapest month to fly from GSP to BUF is September when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Enter GSP to BUF and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
American Airlines is one of the cheapest airlines offering connecting flights from Greenville-Spartanburg Intl. (GSP) to Buffalo Niagara Intl. (BUF), with round-trip tickets starting from around $300. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
To find a cheap flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The earliest flight from Greenville-Spartanburg International Airport (GSP) to Buffalo, NY (BUF-Buffalo Niagara Intl.) typically departs at around 5:00 AM local time, operated by American Airlines. This seasonal service is active in October, allowing you to start your day early and enjoy more time in Buffalo. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The most popular departure times for flights from Greenville-Spartanburg International Airport (GSP) to Buffalo Niagara International Airport (BUF) are in the early morning, from 6am to 9am. This time window accounts for around 40% of total traffic. Many major carriers, including American Airlines, Delta Air Lines and Southwest Airlines, offer flights during this window. Many travelers prefer this time because it allows for a timely arrival in Buffalo to start their day.
How long does it take to fly from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
A flight from GSP to BUF with a layover takes around 4 hours, with the route covering approximately 586 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
You can fly first class between GSP and BUF. First class cabins are available on:

  • American Airlines
  • Delta Air Lines
  • United Airlines

How do I earn miles on a Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight with Expedia?
It's easy to earn miles on a Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Buffalo from Greenville-Spartanburg Intl. (GSP)?
From Greenville-Spartanburg Intl. (GSP), you can fly into Buffalo Niagara Intl. (BUF) to reach Buffalo. Some flights may connect through major hubs like Washington Dulles Intl. (IAD), O'Hare Intl. (ORD), Liberty Intl. (EWR) before reaching Buffalo. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) at the last minute?
Typically, booking a last minute flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight and hotel package?
Securing a Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) Buffalo Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
If you booked your Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Greenville-Spartanburg Intl.
Destination airport
Buffalo Niagara Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$308
Distance
586 mi

Book with confidence

Greenville to Buffalo Flights

The cheapest times to fly from Greenville to Buffalo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Greenville to Buffalo are during the month of September. You can find some of the cheapest flights from Greenville to Buffalo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Greenville to Buffalo

Sunday is one of the best days to book for cheap flights from Greenville to Buffalo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Greenville to Buffalo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Greenville to Buffalo in 2026. You can also book with separate airlines for your outbound and return journeys, from $155 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Greenville to Buffalo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Greenville to Buffalo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Greenville to Buffalo Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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