$136 Cheap Flights from Greenville (GSP) to Buffalo (BUF)

View $136 flight on Wed, Jun 3, 2026Opens in a new window

Popular airlines from Greenville-Spartanburg Intl. Airport (GSP) to Buffalo Niagara Intl. Airport (BUF)

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Cheap Flights from Greenville to Buffalo (GSP-BUF)

Prices were available within the past 7 days and start at $136 for one-way flights and $271 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Tue, May 12 - Wed, Jun 10
GSP
Greenville
BUF
Buffalo
$271 Roundtrip, found 5 days ago
$271
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, May 12 from Greenville to Buffalo, returning Wed, Jun 10, priced at $271 found 5 days ago
Delta
Tue, Aug 25 - Wed, Aug 26
GSP
Greenville
BUF
Buffalo
$271 Roundtrip, found 6 days ago
$271
Roundtrip
found 6 days ago
Select Delta flight, departing Tue, Aug 25 from Greenville to Buffalo, returning Wed, Aug 26, priced at $271 found 6 days ago
Southwest Airlines
Tue, May 12 - Wed, Jun 10
GSP
Greenville
BUF
Buffalo
$271 Roundtrip, found 5 days ago
$271
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Tue, May 12 from Greenville to Buffalo, returning Wed, Jun 10, priced at $271 found 5 days ago
American Airlines
Tue, Aug 25 - Wed, Aug 26
GSP
Greenville
BUF
Buffalo
$278 Roundtrip, found 6 days ago
$278
Roundtrip
found 6 days ago
Select American Airlines flight, departing Tue, Aug 25 from Greenville to Buffalo, returning Wed, Aug 26, priced at $278 found 6 days ago
American Airlines
Tue, May 12 - Wed, Jun 10
GSP
Greenville
BUF
Buffalo
$279 Roundtrip, found 5 days ago
$279
Roundtrip
found 5 days ago
Select American Airlines flight, departing Tue, May 12 from Greenville to Buffalo, returning Wed, Jun 10, priced at $279 found 5 days ago
American Airlines
Wed, Jun 3 - Sat, Jun 6
GSP
Greenville
BUF
Buffalo
$281 Roundtrip, found 1 hour ago
$281
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Wed, Jun 3 from Greenville to Buffalo, returning Sat, Jun 6, priced at $281 found 1 hour ago
United
Thu, May 7 - Tue, May 12
GSP
Greenville
BUF
Buffalo
$281 Roundtrip, found 1 day ago
$281
Roundtrip
found 1 day ago
Select United flight, departing Thu, May 7 from Greenville to Buffalo, returning Tue, May 12, priced at $281 found 1 day ago
American Airlines
Tue, Aug 25 - Wed, Aug 26
GSP
Greenville
BUF
Buffalo
$281 Roundtrip, found 6 days ago
$281
Roundtrip
found 6 days ago
Select American Airlines flight, departing Tue, Aug 25 from Greenville to Buffalo, returning Wed, Aug 26, priced at $281 found 6 days ago
American Airlines
Tue, Aug 25 - Wed, Aug 26
GSP
Greenville
BUF
Buffalo
$282 Roundtrip, found 6 days ago
$282
Roundtrip
found 6 days ago
Select American Airlines flight, departing Tue, Aug 25 from Greenville to Buffalo, returning Wed, Aug 26, priced at $282 found 6 days ago
American Airlines
Wed, Jun 3 - Sat, Jun 6
GSP
Greenville
BUF
Buffalo
$283 Roundtrip, found 1 hour ago
$283
Roundtrip
found 1 hour ago
Select American Airlines flight, departing Wed, Jun 3 from Greenville to Buffalo, returning Sat, Jun 6, priced at $283 found 1 hour ago

Alternative airports near Buffalo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Buffalo Niagara Intl. BUF. Cheapest and Closest option available. Average driving time to city center is 16 minutes. Flights from $379
BUF
Buffalo Niagara Intl.
CheapestClosest
Average driving time to city center16 min
Flights from $379

Frequently asked questions

How much does a flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) cost?
You can find cheap one-way flights from $136 and cheap return flights from $271 Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) with Expedia. One-way flights usually range from $162 to $644, and return flights typically cost between $323 and $1047. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The cheapest month to fly from GSP to BUF is May when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Enter GSP to BUF and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
American Airlines is one of the cheapest airlines offering connecting flights from Greenville-Spartanburg Intl. (GSP) to Buffalo Niagara Intl. (BUF), with round-trip tickets starting from around $300. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
To find a cheap flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The earliest flight from Greenville-Spartanburg International Airport (GSP) to Buffalo, NY (BUF-Buffalo Niagara Intl.) typically departs at around 5:00 AM local time, operated by American Airlines. This seasonal service is active in October, allowing you to start your day early and enjoy more time in Buffalo. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The most popular departure times for flights from Greenville-Spartanburg International Airport (GSP) to Buffalo Niagara International Airport (BUF) are in the early morning, from 6am to 9am. This time window accounts for around 40% of total traffic. Many major carriers, including American Airlines, Delta Air Lines and Southwest Airlines, offer flights during this window. Many travelers prefer this time because it allows for a timely arrival in Buffalo to start their day.
How long does it take to fly from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
A flight from GSP to BUF with a layover takes around 4 hours, with the route covering approximately 586 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
You can fly first class between GSP and BUF. First class cabins are available on:

  • American Airlines
  • Delta Air Lines
  • United Airlines

How do I earn miles on a Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight with Expedia?
It's easy to earn miles on a Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Buffalo from Greenville-Spartanburg Intl. (GSP)?
From Greenville-Spartanburg Intl. (GSP), you can fly into Buffalo Niagara Intl. (BUF) to reach Buffalo. Some flights may connect through major hubs like Washington Dulles Intl. (IAD), O'Hare Intl. (ORD), Liberty Intl. (EWR) before reaching Buffalo. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) at the last minute?
Typically, booking a last minute flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight and hotel package?
Securing a Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) Buffalo Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
If you booked your Greenville, SC (GSP-Greenville-Spartanburg Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Greenville-Spartanburg Intl.
Destination airport
Buffalo Niagara Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$270
Distance
586 mi

Book with confidence

Greenville to Buffalo Flights

The cheapest times to fly from Greenville to Buffalo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Greenville to Buffalo are during the month of May. You can find some of the cheapest flights from Greenville to Buffalo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Greenville to Buffalo

Sunday is one of the best days to book for cheap flights from Greenville to Buffalo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Greenville to Buffalo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Greenville to Buffalo in 2026. You can also book with separate airlines for your outbound and return journeys, from $136 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Greenville to Buffalo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Greenville to Buffalo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Greenville to Buffalo Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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