$139 Cheap Flights from Myrtle Beach (MYR) to Buffalo (BUF)

Popular airlines from Myrtle Beach Intl. Airport (MYR) to Buffalo Niagara Intl. Airport (BUF)

  • Be in the know

    Get alerts if flight prices drop or rise*
  • Book smarter

    Save up to 30% on select hotels after you book a flight*
  • Earn twice

    Earn your airline miles on top of our OneKeyCash

Cheap Flights from Myrtle Beach to Buffalo (MYR-BUF)

Prices were available within the past 7 days and start at $139 for one-way flights and $272 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

United
American Airlines
Delta
Southwest Airlines
United
American Airlines
American Airlines
Southwest Airlines
Southwest Airlines
United

Alternative airports near Buffalo

Prices were available within the past 7 days. Prices and availability are subject to change.

Frequently asked questions

How much does a flight from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) cost?
You can find cheap one-way flights from $139 and cheap return flights from $272 Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) with Expedia. One-way flights usually range from $148 to $1282, and return flights typically cost between $315 and $973. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
March is the cheapest month to fly from Myrtle Beach to Buffalo, with average return fares around $256. This price is about 23% lower than the average throughout the year, as demand tends to dip after the winter months. Other affordable months for this route include May and September.*Averages based on flights available on Expedia in the last year.
Which airlines fly direct from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Enter MYR to BUF and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
How do I find cheap flights from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
To find a cheap flight from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
For flights from Myrtle Beach, SC (MYR) to Buffalo, NY (BUF), March and September are your best options. Average return flight prices are around $256, making it an affordable choice. March is great for early spring travel, while September allows you to enjoy the beautiful fall scenery in New York.*Prices based on flights available on Expedia in the last year.
What is the earliest flight from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The earliest flight from Myrtle Beach International Airport (MYR) to Buffalo Niagara International Airport (BUF) typically departs at around 5:00 AM, operated by American Airlines. This seasonal service is active in December, allowing you to maximize your time in Buffalo. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The most popular departure times for flights from Myrtle Beach (MYR) to Buffalo (BUF) are in the early afternoon, from 12pm to 3pm. About 28% of passengers prefer this time window. Many major carriers, including American Airlines, Southwest Airlines and Delta Air Lines, offer flights during this window. This timing works well because it allows travelers to enjoy their morning before heading to the airport.
How long does it take to fly from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
A flight from MYR to BUF with a layover takes around 4 hours 30 minutes, with the route covering approximately 639 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
You can fly first class between MYR and BUF. First class cabins are available on:

  • Delta Air Lines
  • American Airlines
  • United Airlines

How do I earn miles on a Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight with Expedia?
It's easy to earn miles on a Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Buffalo from MYR (MYR)?
From MYR (MYR), you can fly into Buffalo Niagara Intl. (BUF) to reach Buffalo. Some flights may connect through major hubs like Liberty Intl. (EWR), Charlotte-Douglas Intl. (CLT), Hartsfield-Jackson Atlanta Intl. (ATL) before reaching Buffalo. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) at the last minute?
Typically, booking a last minute flight from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight and hotel package?
Securing a Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) Buffalo Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
If you booked your Myrtle Beach, SC (MYR-Myrtle Beach Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Myrtle Beach Intl.
Destination airport
Buffalo Niagara Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$272
Distance
639 mi

*Flight schedules are subject to change.

*Available to One Key members.

 

Explore a world of travel with Expedia