$142 Cheap Flights from Sioux Falls (FSD) to Key West (EYW)

View $142 flight on Wed, Sep 3, 2025Opens in a new window

Popular airlines from Sioux Falls Regional Airport (FSD) to Key West Intl. Airport (EYW)

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Cheap Flights from Sioux Falls to Key West (FSD-EYW)

Prices were available within the past 7 days and start at $142 for one-way flights and $283 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Tue, Aug 19 - Sat, Sep 6
FSD
Sioux Falls
EYW
Key West
$283 Roundtrip, found 11 hours ago
$283
Roundtrip
found 11 hours ago
Select Delta flight, departing Tue, Aug 19 from Sioux Falls to Key West, returning Sat, Sep 6, priced at $283 found 11 hours ago
Delta
Sun, Aug 24 - Sat, Sep 6
FSD
Sioux Falls
EYW
Key West
$286 Roundtrip, found 11 hours ago
$286
Roundtrip
found 11 hours ago
Select Delta flight, departing Sun, Aug 24 from Sioux Falls to Key West, returning Sat, Sep 6, priced at $286 found 11 hours ago
American Airlines
Sat, Jan 10 - Wed, Jan 14
FSD
Sioux Falls
EYW
Key West
$288 Roundtrip, found 6 hours ago
$288
Roundtrip
found 6 hours ago
Select American Airlines flight, departing Sat, Jan 10 from Sioux Falls to Key West, returning Wed, Jan 14, priced at $288 found 6 hours ago
United
Fri, May 8 - Fri, May 15
FSD
Sioux Falls
EYW
Key West
$289 Roundtrip, found 4 days ago
$289
Roundtrip
found 4 days ago
Select United flight, departing Fri, May 8 from Sioux Falls to Key West, returning Fri, May 15, priced at $289 found 4 days ago
Delta
Fri, Aug 15 - Sat, Aug 30
FSD
Sioux Falls
EYW
Key West
$291 Roundtrip, found 11 hours ago
$291
Roundtrip
found 11 hours ago
Select Delta flight, departing Fri, Aug 15 from Sioux Falls to Key West, returning Sat, Aug 30, priced at $291 found 11 hours ago
American Airlines
Wed, Sep 3 - Wed, Sep 10
FSD
Sioux Falls
EYW
Key West
$293 Roundtrip, found 1 day ago
$293
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Sep 3 from Sioux Falls to Key West, returning Wed, Sep 10, priced at $293 found 1 day ago
Delta
Fri, Aug 15 - Thu, Sep 4
FSD
Sioux Falls
EYW
Key West
$294 Roundtrip, found 11 hours ago
$294
Roundtrip
found 11 hours ago
Select Delta flight, departing Fri, Aug 15 from Sioux Falls to Key West, returning Thu, Sep 4, priced at $294 found 11 hours ago
Delta
Tue, Sep 2 - Sat, Sep 6
FSD
Sioux Falls
EYW
Key West
$306 Roundtrip, found 1 day ago
$306
Roundtrip
found 1 day ago
Select Delta flight, departing Tue, Sep 2 from Sioux Falls to Key West, returning Sat, Sep 6, priced at $306 found 1 day ago
Delta
Sun, Aug 24 - Tue, Sep 9
FSD
Sioux Falls
EYW
Key West
$309 Roundtrip, found 11 hours ago
$309
Roundtrip
found 11 hours ago
Select Delta flight, departing Sun, Aug 24 from Sioux Falls to Key West, returning Tue, Sep 9, priced at $309 found 11 hours ago
Delta
Tue, Aug 12 - Fri, Aug 29
FSD
Sioux Falls
EYW
Key West
$311 Roundtrip, found 11 hours ago
$311
Roundtrip
found 11 hours ago
Select Delta flight, departing Tue, Aug 12 from Sioux Falls to Key West, returning Fri, Aug 29, priced at $311 found 11 hours ago

Find the cheapest month to fly from Sioux Falls (FSD) to Key West (EYW)

September is typically the cheapest month to fly

From $256 - $718 per traveler.

Graph displaying average flight prices per month

Alternative airports near Key West

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Key West Intl. EYW. Cheapest and Closest option available. Average driving time to city center is 8 minutes. Flights from $476
EYW
Key West Intl.
CheapestClosest
Average driving time to city center8 min
Flights from $476
Flights from Sioux Falls (FSD) to Key West (EYW)
Origin airport
Sioux Falls Regional
Destination airport
Key West Intl.
Airlines serving
American Airlines, Delta, United
Roundtrip price
$282
Distance
1563 mi

Sioux Falls to Key West Flights

The cheapest times to fly from Sioux Falls to Key West

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Sioux Falls to Key West are during the month of August. You can find some of the cheapest flights from Sioux Falls to Key West with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Sioux Falls to Key West

Sunday is one of the best days to book for cheap flights from Sioux Falls to Key West: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Sioux Falls to Key West

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Sioux Falls to Key West in 2025. You can also book with separate airlines for your outbound and return journeys, from $142 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Sioux Falls to Key West flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Sioux Falls to Key West airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Sioux Falls Regional Airport (FSD) to Key West Intl. Airport (EYW) cost?
Discover the latest flight deals from FSD to EYW by entering your preferred travel dates and searching on Expedia. Easily compare prices by departure date if you have flexibility with your schedule and use handy filters to explore prices for your preferred journey. As a member of One Key™, our free loyalty program, you can use Price Tracking to watch fares and receive notifications if prices go up or down.
What is the cheapest month to fly from FSD to EYW?
The cheapest flights from FSD to EYW are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from FSD to EYW?
Use the filter tool on Expedia to compare airlines and find the cheapest carrier that'll take you from FSD to EYW. Sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from Sioux Falls Regional Airport (FSD) to Key West Intl. Airport (EYW)?
Nonstop flights from Sioux Falls Regional Airport (FSD) to Key West Intl. Airport (EYW) aren't available daily, so you'll need to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your dates and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from FSD to EYW?
Friday is typically the busiest day for flights, while Tuesday tends to be the quietest.* Just remember that flight schedules can change based on a number of factors, such as the season and airline.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Sioux Falls Regional Airport (FSD) to Key West Intl. Airport (EYW)?
Choose a flight from Sioux Falls Regional Airport (FSD) to Key West Intl. Airport (EYW) that leaves before 3 PM to reduce the risk of cancellations and delays. Later departures have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Sioux Falls Regional Airport (FSD) to Key West Intl. Airport (EYW) last-minute?
Booking your flight from FSD to EYW shortly before your journey is usually more expensive. However, if there's some wiggle room with your itinerary, you could snag a cheap last-minute fare.
Is it cheaper to book a FSD to EYW flight and hotel package?
You'll typically save money by booking a FSD to EYW flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one convenient place. Once you've selected your preferred flights and accommodations, consider other add-ons like activities, tours and car rentals.
Can I cancel or change the date of my flight from Sioux Falls Regional Airport (FSD) to Key West Intl. Airport (EYW)?
If you reserved your FSD to EYW flight in the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for more information.

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*Available to One Key members.