$239 Cheap Flights from Guayaquil (GYE) to Santiago (SCL)

View $239 flight on Mon, Sep 1, 2025Opens in a new window

Popular airlines from Jose Joaquin de Olmedo Intl. Airport (GYE) to Santiago Intl. Airport (SCL)

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Cheap Flights from Guayaquil to Santiago (GYE-SCL)

Prices were available within the past 7 days and start at $239 for one-way flights and $457 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Tue, Aug 26 - Wed, Sep 3
GYE
Guayaquil
SCL
Santiago
$457 Roundtrip, found 8 hours ago
$457
Roundtrip
found 8 hours ago
Select Copa flight, departing Tue, Aug 26 from Guayaquil to Santiago, returning Wed, Sep 3, priced at $457 found 8 hours ago
Copa
Wed, Nov 5 - Sun, Nov 9
GYE
Guayaquil
SCL
Santiago
$458 Roundtrip, found 6 hours ago
$458
Roundtrip
found 6 hours ago
Select Copa flight, departing Wed, Nov 5 from Guayaquil to Santiago, returning Sun, Nov 9, priced at $458 found 6 hours ago
LATAM Airlines Group
Mon, Aug 18 - Fri, Aug 22
GYE
Guayaquil
SCL
Santiago
$462 Roundtrip, found 4 hours ago
$462
Roundtrip
found 4 hours ago
Select LATAM Airlines Group flight, departing Mon, Aug 18 from Guayaquil to Santiago, returning Fri, Aug 22, priced at $462 found 4 hours ago
Copa
Wed, Nov 5 - Mon, Nov 10
GYE
Guayaquil
SCL
Santiago
$471 Roundtrip, found 6 hours ago
$471
Roundtrip
found 6 hours ago
Select Copa flight, departing Wed, Nov 5 from Guayaquil to Santiago, returning Mon, Nov 10, priced at $471 found 6 hours ago
Copa
Mon, Sep 1 - Sun, Sep 7
GYE
Guayaquil
SCL
Santiago
$474 Roundtrip, just found
$474
Roundtrip
just found
Select Copa flight, departing Mon, Sep 1 from Guayaquil to Santiago, returning Sun, Sep 7, priced at $474 just found
LATAM Airlines Group
Mon, Aug 18 - Fri, Aug 22
GYE
Guayaquil
SCL
Santiago
$481 Roundtrip, found 4 hours ago
$481
Roundtrip
found 4 hours ago
Select LATAM Airlines Group flight, departing Mon, Aug 18 from Guayaquil to Santiago, returning Fri, Aug 22, priced at $481 found 4 hours ago
Copa
Mon, Sep 1 - Sun, Sep 7
GYE
Guayaquil
SCL
Santiago
$481 Roundtrip, just found
$481
Roundtrip
just found
Select Copa flight, departing Mon, Sep 1 from Guayaquil to Santiago, returning Sun, Sep 7, priced at $481 just found
Copa
Tue, Aug 26 - Sat, Aug 30
GYE
Guayaquil
SCL
Santiago
$482 Roundtrip, found 6 hours ago
$482
Roundtrip
found 6 hours ago
Select Copa flight, departing Tue, Aug 26 from Guayaquil to Santiago, returning Sat, Aug 30, priced at $482 found 6 hours ago
LATAM Airlines Group
Mon, Sep 1 - Sun, Sep 7
GYE
Guayaquil
SCL
Santiago
$483 Roundtrip, just found
$483
Roundtrip
just found
Select LATAM Airlines Group flight, departing Mon, Sep 1 from Guayaquil to Santiago, returning Sun, Sep 7, priced at $483 just found
avianca
Sun, Aug 10 - Sun, Aug 31
GYE
Guayaquil
SCL
Santiago
$599 Roundtrip, just found
$599
Roundtrip
just found
Select avianca flight, departing Sun, Aug 10 from Guayaquil to Santiago, returning Sun, Aug 31, priced at $599 just found

Find the cheapest month to fly from Guayaquil (GYE) to Santiago (SCL)

March is typically the cheapest month to fly

From $321 - $571 per traveler.

Graph displaying average flight prices per month

Alternative airports near Santiago

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Arturo Merino Benitez SCL. Cheapest and Closest option available. Average driving time to city center is 17 minutes. Flights from $534
SCL
Arturo Merino Benitez
CheapestClosest
Average driving time to city center17 min
Flights from $534
Flights from Guayaquil (GYE) to Santiago (SCL)
Origin airport
Jose Joaquin de Olmedo Intl.
Destination airport
Arturo Merino Benitez
Airlines serving
Copa, LATAM Airlines Group, avianca
Roundtrip price
$457
Distance
2237 mi
Average flight time
3 hours 53 mins

Guayaquil to Santiago Flights

The cheapest times to fly from Guayaquil to Santiago

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Guayaquil to Santiago are during the month of August. You can find some of the cheapest flights from Guayaquil to Santiago with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Guayaquil to Santiago

Sunday is one of the best days to book for cheap flights from Guayaquil to Santiago: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Guayaquil to Santiago

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Guayaquil to Santiago in 2025. You can also book with separate airlines for your outbound and return journeys, from $239 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Guayaquil to Santiago flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Guayaquil to Santiago airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Jose Joaquin de Olmedo Intl. Airport (GYE) to Arturo Merino Benitez Airport (SCL) cost?
Find affordable return tickets from Jose Joaquin de Olmedo Intl. Airport (GYE) to Arturo Merino Benitez Airport (SCL) starting at $515. Book your seat and take off on your trip. This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a LATAM Airlines Group flight leaving GYE on August 8 2025 and touching down at SCL. The price was last updated on July 13 2025 and has not changed since.
What is the cheapest month to fly from GYE to SCL?
The cheapest flights from GYE to SCL are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
Which airlines fly direct from Jose Joaquin de Olmedo Intl. Airport (GYE) to Arturo Merino Benitez Airport (SCL)?
Take a direct flight with LATAM Airlines and journey straight from Jose Joaquin de Olmedo Intl. Airport (GYE) to Arturo Merino Benitez Airport (SCL).
What is the cheapest airline that flies from GYE to SCL?
Currently, the cheapest airline offering one-way flights from GYE to SCL is LATAM Airlines Group. You can take off on this route from $268. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from GYE on October 8 2025. Prices were last updated on July 13 2025 and have not changed since.
How many flights per day from Jose Joaquin de Olmedo Intl. Airport (GYE) to Arturo Merino Benitez Airport (SCL)?
On average, only 1 direct flight departs each day from Jose Joaquin de Olmedo Intl. Airport (GYE) to Arturo Merino Benitez Airport (SCL). Looking for more options? Use Expedia's filters to find flights with layovers and add a new destination to your journey.
What are the most popular departure times for flights from Jose Joaquin de Olmedo Intl. Airport (GYE) to Arturo Merino Benitez Airport (SCL)?
The 2 PM departures from GYE to SCL are the most sought after. Prices can be higher for these popular slots. If you want to save on your fare, pick a less crowded time to fly.
What day of the week has the most flights from GYE to SCL?
Travel on a Friday if you're looking for the best choice of flights from Jose Joaquin de Olmedo Intl. Airport (GYE) to Arturo Merino Benitez Airport (SCL).
What is the earliest flight from Jose Joaquin de Olmedo Intl. Airport (GYE) to Arturo Merino Benitez Airport (SCL)?
Catch the earliest flight at around 2:45PM UTC-5, departing from Jose Joaquin de Olmedo Intl. Airport (GYE). You'll be traveling for around 4h 48m, arriving at Arturo Merino Benitez Airport (SCL) at approximately 9:33PM UTC-3.
How long does it take to fly from Jose Joaquin de Olmedo Intl. Airport (GYE) to Arturo Merino Benitez Airport (SCL)?
Flights from GYE to SCL have an average travel time of 4 hours and 48 minutes. The total distance between the two is 2,200 mi.
What airline has the least delays from GYE to SCL?
With 100% of flights generally arriving as scheduled, Qantas has the best on-time performance for nonstop flights from Jose Joaquin de Olmedo Intl. Airport (GYE) to Arturo Merino Benitez Airport (SCL). To monitor your flight status and receive notifications if anything changes, simply head to the Expedia App.
What is the best time to fly from Jose Joaquin de Olmedo Intl. Airport (GYE) to Arturo Merino Benitez Airport (SCL)?
Opt for a flight from Jose Joaquin de Olmedo Intl. Airport (GYE) to Arturo Merino Benitez Airport (SCL) that takes off before 3 PM to reduce the risk of cancellations. Departures after this time are on average 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Santiago from Jose Joaquin de Olmedo Intl. Airport (GYE)?
Arturo Merino Benitez Airport (SCL) is the only airport in Santiago with direct flights from Jose Joaquin de Olmedo Intl. Airport (GYE). Compare the available options and discover cheap fares on Expedia.
Is it cheaper to buy a plane ticket from Jose Joaquin de Olmedo Intl. Airport (GYE) to Arturo Merino Benitez Airport (SCL) last-minute?
Holding off until just before your trip to book your flight from GYE to SCL often results in higher prices. While you may find some last-minute offers, they're not always guaranteed. Keep your travel plans flexible for a better chance of landing a bargain.
Is it cheaper to book a GYE to SCL flight and hotel package?
Opting for a GYE to SCL flight and hotel package is generally cheaper than booking separately. With Expedia, you can enjoy the convenience of organizing your travels all in one place. Select from our wide range of accommodations and then add flights, car rentals and activities to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Jose Joaquin de Olmedo Intl. Airport (GYE) to Arturo Merino Benitez Airport (SCL)?
If you booked your GYE to SCL flight within the last 24 hours, you may be able to modify or cancel it without fees. Depending on the airline and the type of fare you have, additional charges may apply for changes after that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

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