$359 Cheap Flights from Quito (UIO) to Antofagasta (ANF)

View $359 flight on Thu, Dec 25, 2025Opens in a new window

Popular airlines from Mariscal Sucre Intl. Airport (UIO) to Antofagasta (ANF-Cerro Moreno Intl.)

Cheap Flights from Quito to Antofagasta (UIO-ANF)

Prices were available within the past 7 days and start at $359 for one-way flights and $473 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Jetsmart SPA
Sun, Feb 1 - Thu, Feb 12
UIO
Quito
ANF
Antofagasta
$473 Roundtrip, found 2 days ago
$473
Roundtrip
found 2 days ago
Select Jetsmart SPA flight, departing Sun, Feb 1 from Quito to Antofagasta, returning Thu, Feb 12, priced at $473 found 2 days ago
LATAM Airlines Group
Fri, Nov 7 - Sat, Nov 22
UIO
Quito
ANF
Antofagasta
$479 Roundtrip, found 19 hours ago
$479
Roundtrip
found 19 hours ago
Select LATAM Airlines Group flight, departing Fri, Nov 7 from Quito to Antofagasta, returning Sat, Nov 22, priced at $479 found 19 hours ago
Jetsmart SPA
Wed, Dec 3 - Sat, Dec 6
UIO
Quito
ANF
Antofagasta
$480 Roundtrip, found 2 days ago
$480
Roundtrip
found 2 days ago
Select Jetsmart SPA flight, departing Wed, Dec 3 from Quito to Antofagasta, returning Sat, Dec 6, priced at $480 found 2 days ago
Jetsmart SPA
Sun, Jan 25 - Fri, Feb 6
UIO
Quito
ANF
Antofagasta
$484 Roundtrip, found 2 days ago
$484
Roundtrip
found 2 days ago
Select Jetsmart SPA flight, departing Sun, Jan 25 from Quito to Antofagasta, returning Fri, Feb 6, priced at $484 found 2 days ago
Jetsmart SPA
Wed, Jan 28 - Tue, Feb 10
UIO
Quito
ANF
Antofagasta
$485 Roundtrip, found 19 hours ago
$485
Roundtrip
found 19 hours ago
Select Jetsmart SPA flight, departing Wed, Jan 28 from Quito to Antofagasta, returning Tue, Feb 10, priced at $485 found 19 hours ago
Jetsmart SPA
Wed, Dec 24 - Fri, Jan 9
UIO
Quito
ANF
Antofagasta
$487 Roundtrip, found 2 days ago
$487
Roundtrip
found 2 days ago
Select Jetsmart SPA flight, departing Wed, Dec 24 from Quito to Antofagasta, returning Fri, Jan 9, priced at $487 found 2 days ago
Jetsmart SPA
Sun, Dec 28 - Sat, Jan 17
UIO
Quito
ANF
Antofagasta
$491 Roundtrip, found 19 hours ago
$491
Roundtrip
found 19 hours ago
Select Jetsmart SPA flight, departing Sun, Dec 28 from Quito to Antofagasta, returning Sat, Jan 17, priced at $491 found 19 hours ago
LATAM Airlines Group
Fri, Nov 7 - Mon, Nov 17
UIO
Quito
ANF
Antofagasta
$493 Roundtrip, found 19 hours ago
$493
Roundtrip
found 19 hours ago
Select LATAM Airlines Group flight, departing Fri, Nov 7 from Quito to Antofagasta, returning Mon, Nov 17, priced at $493 found 19 hours ago
Jetsmart SPA
Wed, Dec 24 - Thu, Jan 8
UIO
Quito
ANF
Antofagasta
$494 Roundtrip, found 2 days ago
$494
Roundtrip
found 2 days ago
Select Jetsmart SPA flight, departing Wed, Dec 24 from Quito to Antofagasta, returning Thu, Jan 8, priced at $494 found 2 days ago
LATAM Airlines Group
Mon, Nov 17 - Thu, Dec 4
UIO
Quito
ANF
Antofagasta
$495 Roundtrip, found 19 hours ago
$495
Roundtrip
found 19 hours ago
Select LATAM Airlines Group flight, departing Mon, Nov 17 from Quito to Antofagasta, returning Thu, Dec 4, priced at $495 found 19 hours ago

Frequently asked questions

How much does a flight from Mariscal Sucre Intl. Airport (UIO) to Cerro Moreno Intl. Airport (ANF) cost?
Lock in a cheap one-way flight from $359 or cheap return flight from $473 from Mariscal Sucre Intl. Airport (UIO) to Cerro Moreno Intl. Airport (ANF) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Mariscal Sucre Intl. Airport (UIO) to Cerro Moreno Intl. Airport (ANF)?
The cheapest month to fly from UIO to ANF is February, when there's less demand. Off-peak season is often when you'll find lower airfares between these airports.
What is the cheapest airline that flies from Mariscal Sucre Intl. Airport (UIO) to Cerro Moreno Intl. Airport (ANF)?
To find the cheapest airline that'll fly you from UIO to ANF, use Expedia's filter tool. Customize your search based on your travel style, such as preferred carriers and flight duration. You can then sort your results by "Price (lowest to highest)" to list the most affordable options first.
How many flights per day from Mariscal Sucre Intl. Airport (UIO) to Cerro Moreno Intl. Airport (ANF)?
You'll need to book a flight with a layover if you're traveling from Mariscal Sucre Intl. Airport (UIO) to Cerro Moreno Intl. Airport (ANF). There are no daily direct flights on this route. However, simply filter your search to include one or two stops to find the best option for your trip.
What day of the week has the most flights from UIO to ANF?
Usually you'll find the largest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* However, this can vary depending on the time of year, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Mariscal Sucre Intl. Airport (UIO) to Cerro Moreno Intl. Airport (ANF)?
Book a flight from Mariscal Sucre Intl. Airport (UIO) to Cerro Moreno Intl. Airport (ANF) that leaves before 3 PM to reduce the likelihood of delays. Departures later than this have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Mariscal Sucre Intl. Airport (UIO) to Cerro Moreno Intl. Airport (ANF) last-minute?
Holding off until just before your departure to book a ticket from UIO to ANF generally means paying more. While it's possible to find some last-minute deals, there's no guarantee. Keep your travel plans flexible for a better chance of scoring a bargain.
Is it cheaper to book an UIO to ANF flight and hotel package?
You can save money by securing an UIO to ANF flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one place. Once you've selected your preferred flights and accommodations, consider other add-ons like tours, activities and car rentals.
Can I cancel or change the date of my flight from Mariscal Sucre Intl. Airport (UIO) to Cerro Moreno Intl. Airport (ANF)?
Typically, you can reschedule or cancel your UIO to ANF flight. However, there may be additional fees, especially if your booking was made over 24 hours ago. Check your itinerary for the airline's rules and fees on flight changes, or if you need more details, go to our Customer Service portal.

Travel information

Origin airport
Mariscal Sucre Intl.
Destination airport
Cerro Moreno Intl.
Airlines serving
Jetsmart SPA, LATAM Airlines Group
Roundtrip price
$472
Distance
1696 mi

Book with confidence

Quito to Antofagasta Flights

The cheapest times to fly from Quito to Antofagasta

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Quito to Antofagasta are during the month of February. You can find some of the cheapest flights from Quito to Antofagasta with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Quito to Antofagasta

Sunday is one of the best days to book for cheap flights from Quito to Antofagasta: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Quito to Antofagasta

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Quito to Antofagasta in 2025. You can also book with separate airlines for your outbound and return journeys, from $359 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Quito to Antofagasta flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Quito to Antofagasta airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Quito to Antofagasta Flights

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*Available to One Key members.