Photo by Ryan Watts

Find 2 Star Hotels in Upstate South Carolina, SC from $48

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Compare Upstate South Carolina 2 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Days Inn by Wyndham Anderson

2.0 star property
Anderson
7.8 out of 10, Good, (1028)
"Like most motels, it was kind of sketch, but it made do. Honestly a pretty decent place to stay. "
United States
Liam
$63 nightly
The price is $70
Dec 7 - Dec 8
Total with taxes and fees
Days Inn by Wyndham Anderson

Best Western Plus Greenville I-385 Inn & Suites

2.5 star property
Greenville
9.0 out of 10, Wonderful, (1405)
"Loved my stay. "
United States
Himani
$104 nightly
The price is $115
Dec 19 - Dec 20
Total with taxes and fees
Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Clemson Hotel & Conference Center

2.5 star property
Clemson
8.2 out of 10, Very Good, (1001)
" Clean room, breakfast, staff very nice."
United States
Maria Claudia
$93 nightly
The price is $103
Dec 21 - Dec 22
Total with taxes and fees
Best Western Plus Clemson Hotel & Conference Center

Quality Inn Seneca Clemson Area US-123

2.5 star property
Downtown
8.0 out of 10, Very Good, (664)
"Friendly check in, clean room."
United States
connie
$79 nightly
The price is $87
Dec 14 - Dec 15
Total with taxes and fees
Quality Inn Seneca Clemson Area US-123

ECHO Suites Extended Stay by Wyndham Spartanburg

2.0 star property
Spartanburg
8.2 out of 10, Very Good, (281)
"Nice hotel "
United States
Kierra
$73 nightly
The price is $81
Dec 8 - Dec 9
Total with taxes and fees
ECHO Suites Extended Stay by Wyndham Spartanburg

Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

2.0 star property
Greenville
8.2 out of 10, Very Good, (1001)
"I enjoyed my stay"
United States
Vanessa
$70 nightly
The price is $77
Dec 18 - Dec 19
Total with taxes and fees
Microtel Inn & Suites by Wyndham Greenville / Woodruff Rd

Comfort Suites Greenville Airport

2.5 star property
Greenville
9.4 out of 10, Exceptional, (1017)
"Me and my family stay here before I enjoyed the friendly staff and the hospitality at the hotel.. Nice breakfast as well.."
United States
jessie
$101 nightly
The price is $111
Dec 20 - Dec 21
Total with taxes and fees
Comfort Suites Greenville Airport

Comfort Inn & Suites Clemson - University Area

2.5 star property
Clemson
8.2 out of 10, Very Good, (1000)
"Great stay "
United States
Linda
$97 nightly
The price is $108
Dec 9 - Dec 10
Total with taxes and fees
Comfort Inn & Suites Clemson - University Area

Motel 6 Greenville, SC

2.0 star property
Greenville
5.0 out of 10, (690)
"Very well accommodated"
United States
Patricia
$49 nightly
The price is $54
Dec 8 - Dec 9
Total with taxes and fees
Motel 6 Greenville, SC

Comfort Inn Greenville - Haywood Mall

2.5 star property
Greenville
8.0 out of 10, Very Good, (1011)
"Staff was very friendly, clean rooms, only downside is I ended up being sick during my trip and had to spend some time in the room to relax, but the tv didn’t work :( "
United States
Amanda
$88 nightly
The price is $96
Dec 7 - Dec 8
Total with taxes and fees
Comfort Inn Greenville - Haywood Mall

Comfort Suites At WestGate Mall

2.5 star property
Spartanburg
8.2 out of 10, Very Good, (1015)
"Easy parking, parking lot had good lighting felt safe Breakfast had great choices always hot, I always like their waffles Rooms clean and spacious, bed was comfortable"
United States
Ronald
$93 nightly
The price is $103
Jan 1 - Jan 2, 2026
Total with taxes and fees
Comfort Suites At WestGate Mall

Woodspring Suites Greenville Airport

2.5 star property
Greenville
8.2 out of 10, Very Good, (293)
"Clean room, friendly staff, I would definitely stay here again!"
United States
Melissa
$79 nightly
The price is $87
Dec 4 - Dec 5
Total with taxes and fees
Woodspring Suites Greenville Airport

Microtel Inn & Suites by Wyndham Anderson/Clemson

2.0 star property
Anderson
8.2 out of 10, Very Good, (1008)
"Room was clean, staff was nice! "
United States
Martina
$80 nightly
The price is $89
Dec 4 - Dec 5
Total with taxes and fees
Microtel Inn & Suites by Wyndham Anderson/Clemson

Wingate by Wyndham - Greenville-Airport

2.5 star property
Greenville
8.4 out of 10, Very Good, (1023)
"Room clean front desk excellent nice and quiet "
United States
Joanne
$89 nightly
The price is $98
Dec 7 - Dec 8
Total with taxes and fees
Wingate by Wyndham - Greenville-Airport

SpringHill Suites by Marriott Greenville Downtown

2.5 star property
Greenville Downtown
9.6 out of 10, Exceptional, (1008)
"Loved our stay. Comfortable in every way. Close to all the sites and Christmas fun. Great Breakfast "
United States
Matthew
$118 nightly
The price is $130
Dec 14 - Dec 15
Total with taxes and fees
SpringHill Suites by Marriott Greenville Downtown

Days Inn by Wyndham Clinton / Laurens I-26

2.0 star property
Clinton
6.6 out of 10, (410)
"Seemed safe and reliable’s "
United States
Isabelle
$55 nightly
The price is $62
Dec 26 - Dec 27
Total with taxes and fees
Days Inn by Wyndham Clinton / Laurens I-26

Lakeside Lodge Clemson

2.5 star property
Seneca
9.0 out of 10, Wonderful, (1009)
"Overall great stay."
United States
Daniel
$123 nightly
The price is $135
Dec 4 - Dec 5
Total with taxes and fees
Lakeside Lodge Clemson

Quality Inn Clemson near University

2.5 star property
Anderson
7.0 out of 10, Good, (887)
"Bueno was "
Mexico
Alejandro
$44 nightly
The price is $48
Dec 18 - Dec 19
Total with taxes and fees
Quality Inn Clemson near University

Baymont by Wyndham Easley/Greenville

2.5 star property
Easley
7.4 out of 10, Good, (740)
"Room was nice, and the staff was very friendly. "
United States
Gary
$64 nightly
The price is $71
Dec 4 - Dec 5
Total with taxes and fees
Baymont by Wyndham Easley/Greenville

Tru by Hilton Spartanburg

2.5 star property
Spartanburg
9.2 out of 10, Wonderful, (809)
"Great stay "
United States
Teresa
$95 nightly
The price is $106
Dec 21 - Dec 22
Total with taxes and fees
Tru by Hilton Spartanburg
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Explore similar 3-star hotels

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Learn more about Upstate South Carolina

Venture to sights like Discovery Island Water Park and Heritage Park as you discover Upstate South Carolina.

It is only a 1 mile hike to this beauty.  View a video about it here:  https://www.hdcarolina.com/episode/riley-moore-falls

#Waterfall
Photo by Ryan Watts
Open Photo by Ryan Watts

Top Upstate South Carolina Hotel Reviews

Find out more about Upstate South Carolina

Upstate South Carolina Motel Guide

Planning a getaway with only a few bucks to spare? Expedia can help! With the inexpensive rates at the top motels in Upstate South Carolina, South Carolina you can put together the vacation of your dreams without spending every penny of your yearly travel budget.

These smaller places are ideal if you need a home base that lets you easily explore the local sights; many of the best motels in Upstate South Carolina are located near major freeways and public transportation. Plus, when you book a cheap deal on a motel in Upstate South Carolina, you’ll find quiet rooms, complimentary toiletries, and comfortable sleeping areas, so you can unwind after a long day.

No matter which motel you choose, don't forget to use the travel tools at Expedia to search for local discounts, compare rates on the hottest motels, and plan your next vacation. You won't believe how budget-friendly an amazing getaway can be.

Also, feel free to check out the motels near me page to find the cheapest deals on motels near your current location.

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