Find 4 Star Hotels in Mediterranean Region

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Compare Mediterranean Region 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for Mediterranean Region 4-star hotels

Barcelona Airport Hotel

4.0 star property
8.6 out of 10, Excellent, (5063)
"Good place to stay "
$161 nightly
The price is $181
Sep 5 - Sep 6
Total with taxes and fees
Barcelona Airport Hotel

Hotel Quirinale

4.0 star property
8.6 out of 10, Excellent, (1865)
"Great location "
$243 nightly
The price is $285
Sep 2 - Sep 3
Total with taxes and fees
Hotel Quirinale

Senator Barajas Hotel

4.0 star property
8.4 out of 10, Very Good, (1694)
"So convenient for the airport. Good dining options."
$114 nightly
The price is $126
Sep 7 - Sep 8
Total with taxes and fees
Senator Barajas Hotel

The Stanley

4.0 star property
8.8 out of 10, Excellent, (1971)
"Excellent staff, we really enjoyed our stay"
$184 nightly
The price is $221
Sep 2 - Sep 3
Total with taxes and fees
The Stanley

INNSiDE by Melia Barcelona Apolo

4.0 star property
9.4 out of 10, Exceptional, (1314)
"Outstanding hotel and staff!"
$191 nightly
The price is $225
Sep 2 - Sep 3
Total with taxes and fees
INNSiDE by Melia Barcelona Apolo

Radisson Blu Hotel

4.0 star property
8.2 out of 10, Very Good, (2066)
"Business friendly, transport, nice staff, very clean and comfortable hotel "
$134 nightly
The price is $152
Sep 3 - Sep 4
Total with taxes and fees
Radisson Blu Hotel

Best Western Hotel Rome Airport

4.0 star property
8.2 out of 10, Very Good, (1618)
"Convenient location, next to the airport, free parking, shuttle to the airport and from the airport"
$149 nightly
The price is $178
Sep 7 - Sep 8
Total with taxes and fees
Best Western Hotel Rome Airport

Grand Hotel Baglioni

4.0 star property
9.0 out of 10, Wonderful, (1020)
"Really great location, and the staff was incredibly friendly"
$239 nightly
The price is $280
Sep 5 - Sep 6
Total with taxes and fees
Grand Hotel Baglioni

The Hive Hotel

4.0 star property
9.0 out of 10, Wonderful, (1577)
"Great hotel and location. "
$129 nightly
The price is $160
Sep 2 - Sep 3
Total with taxes and fees
The Hive Hotel

Hilton Rome Airport

4.0 star property
8.0 out of 10, Very Good, (3092)
"Very nice hotel and walkable from the airport."
$253 nightly
The price is $292
Sep 4 - Sep 5
Total with taxes and fees
Hilton Rome Airport

The Social Hub Florence Lavagnini

4.0 star property
9.0 out of 10, Wonderful, (1193)
"Great hotel. "
$133 nightly
The price is $163
Sep 2 - Sep 3
Total with taxes and fees
The Social Hub Florence Lavagnini

Moxy Barcelona

4.0 star property
8.2 out of 10, Very Good, (360)
"Great place to stay."
$143 nightly
The price is $171
Sep 10 - Sep 11
Total with taxes and fees
Moxy Barcelona

Hotel Riu Plaza España

4.0 star property
9.4 out of 10, Exceptional, (4340)
"Great stay"
$221 nightly
The price is $243
Sep 7 - Sep 8
Total with taxes and fees
Hotel Riu Plaza España

Hotel Regina

4.0 star property
9.8 out of 10, Exceptional, (2097)
"Was a great place to stay!"
$180 nightly
The price is $198
Sep 2 - Sep 3
Total with taxes and fees
Hotel Regina

Best Western Premier Hotel Royal Santina

4.0 star property
9.0 out of 10, Wonderful, (1007)
"Very good choice for a short overnight stay if travelling on by train or seekjng to get to Fiumicino airport. Clean hotel, nice rooms, good facilities and very pleasant staff!"
$255 nightly
The price is $298
Sep 3 - Sep 4
Total with taxes and fees
Best Western Premier Hotel Royal Santina

Royal Ramblas

4.0 star property
8.8 out of 10, Excellent, (1020)
"wonderful location friendly staff"
$190 nightly
The price is $224
Sep 2 - Sep 3
Total with taxes and fees
Royal Ramblas

Napoleon Hotel

4.0 star property
8.4 out of 10, Very Good, (1017)
"Excellent place to stay!"
$183 nightly
The price is $219
Sep 2 - Sep 3
Total with taxes and fees
Napoleon Hotel

Hotel Avra by Smile hotels

4.0 star property
9.0 out of 10, Wonderful, (1653)
"Loved our stay!"
$123 nightly
The price is $152
Oct 1 - Oct 2
Total with taxes and fees
Hotel Avra by Smile hotels

Hilton Garden Inn Rome Airport

4.0 star property
8.2 out of 10, Very Good, (3091)
"Great for a stopover"
$199 nightly
The price is $233
Sep 4 - Sep 5
Total with taxes and fees
Hilton Garden Inn Rome Airport

Tivoli Oriente Lisboa Hotel

4.0 star property
9.2 out of 10, Wonderful, (1433)
"Great location, beautiful hotel"
$187 nightly
The price is $208
Sep 13 - Sep 14
Total with taxes and fees
Tivoli Oriente Lisboa Hotel
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Learn more about Mediterranean Region

During your stay in Mediterranean Region, you can discover things to see and do in the local area.

Roman Forum showing a ruin and heritage architecture

Top Mediterranean Region Hotel Reviews

Find out more about Mediterranean Region

Find out more about Mediterranean Region

Mediterranean Region Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Mediterranean Region, are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Mediterranean Region 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Mediterranean Region. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Mediterranean Region, , areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Mediterranean Region hotels offer everything your heart desires.