Find hotels in Cairo, IL from $59

Top reasons to visit Cairo

• Outdoor Adventures: Enjoy activities like hiking, riverboat tours, and camping in scenic areas around Cairo.
• Rich History: Explore local historic forts and immerse yourself in the region's heritage.
• Mississippi River Views: Experience breathtaking views and leisure activities along the iconic river.
• Charming Accommodations: Choose from unique lodging options, including agritourism properties and cozy motels.
• Local Culture: Visit shops and enjoy the warm atmosphere for a taste of regional culture.

Find great hotels in and around Cairo

Explore the unique lodging options in Cairo, Illinois, where you can choose from charming agritourism properties to cozy motels. Whether you're traveling with family, on a business trip, or bringing along your pet, you'll find a range of accommodations tailored to your needs. Discover the best hotels in Cairo, read reviews, and enjoy a memorable stay in this quaint destination.

• Super 8 by Wyndham Charleston/Sikeston East MO: Situated 10 miles from Cairo, Super 8 by Wyndham Charleston/Sikeston East MO offers a welcoming atmosphere for families and pet owners. This motel features child-friendly amenities such as complimentary cribs, ensuring a convenient stay for those traveling with little ones. The pet-friendly policy allows for some furry companions, making it an ideal choice for families looking to travel together. Guests can enjoy a comfortable environment with essential amenities and a friendly staff dedicated to providing a pleasant experience.
• Quality Inn Charleston - Sikeston: Located 12 miles from Cairo, Quality Inn Charleston - Sikeston is a business-centric hotel that caters to professionals while still being pet-friendly. With a well-equipped business center, this hotel provides essential services for those traveling for work. The property has a pet policy that accommodates service animals and permits pets with some restrictions, making it a versatile choice for both business and leisure travelers. Guests appreciate the blend of functionality and comfort, making their stay productive and enjoyable.
• Quality Inn Cairo I-57: Nestled in Cairo, Quality Inn Cairo I-57 is a family-friendly hotel that welcomes pets and offers a range of amenities for children, including complimentary cribs and first aid kits for peace of mind. The hotel’s pet-friendly policy allows dogs, with considerations for cleaning fees and restrictions, making it a suitable option for dog owners. With a commitment to family comfort and safety, guests will find a cozy atmosphere where they can relax after a day of exploration in Cairo.

Where to stay near Cairo

Cairo, Illinois, offers a unique blend of outdoor adventure and rich history, perfect for family-friendly vacations. Explore the scenic views along the Mississippi River, visit local shops for a taste of regional culture, and enjoy the warm weather. Nearby towns provide additional experiences with their charming atmospheres and business-friendly environments. Whether you're hiking in the great outdoors or immersing yourself in local heritage, Cairo promises an unforgettable getaway.

• Wickliffe: Located a short 6 miles from Cairo, Wickliffe is a charming city known for its outdoor beauty and romantic atmosphere. Visitors flock here for its stunning scenery, making it an ideal destination for couples and nature lovers alike. Wickliffe offers a variety of recreational areas and a delightful resort, providing ample opportunities for relaxation and adventure. You can explore the nearby national parks and lakes, perfect for hiking, picnicking, or simply enjoying the scenic views. The arts center also adds a cultural touch to your visit, making Wickliffe a well-rounded destination.
• Mound City: Also situated about 6 miles from Cairo, Mound City is a vibrant spot for those seeking outdoor adventures and scenic explorations. This city appeals to thrill-seekers and nature enthusiasts, offering a variety of activities like golfing and educational experiences. The proximity to beautiful lakes, a national park, and lush forests creates a perfect backdrop for hiking, fishing, or leisurely strolls. Mound City’s welcoming atmosphere and diverse attractions ensure a memorable experience for all visitors, especially in the bustling months of March, July, and October.
• Wyatt: A quaint city located 7 miles from Cairo, Wyatt is perfect for travelers looking for romance and outdoor tranquility. Visitors are drawn to its serene landscapes and recreational areas, ideal for a peaceful escape. The nearby national park and picturesque lakes offer opportunities for boating, fishing, and hiking, making it a great spot to connect with nature. With peak travel times occurring during the warmer months of June to August, Wyatt promises a relaxing getaway filled with beautiful scenery and memorable experiences.

Things to do near Cairo

Cairo, Illinois offers a variety of outdoor adventures and scenic experiences perfect for a vacation. Visitors can enjoy recreational areas for relaxation, explore local golf courses, and partake in riverboat tours along the waterways. For those seeking weekend getaways, there are also camping sites available, along with opportunities for indoor activities. Whether you're looking to unwind or explore, Cairo provides a unique blend of activities for every traveler.

Shopping

Cairo offers charming local shops for unique gifts and souvenirs. For a wider selection, check out the nearby Plaza Shopping Center, about 10 miles away, featuring various retail stores and dining options. If you're up for a drive, you can explore the larger shopping malls in the surrounding areas.

Recreation

eDen Spa & Salon offers a rejuvenating body treatment experience just 28 miles from Cairo. This tranquil venue is designed for wellness and relaxation, providing a perfect escape to unwind and recharge while indulging in professional spa services.

Adventure

Visit Cape Splash Family Aquatic Center for an exciting waterpark experience, located 31 miles from Cairo. Enjoy thrilling slides, wave pools, and family-friendly attractions. For an outdoor adventure, hike the Limekin Springs Trail Trailhead, situated 20 miles away, where you'll find beautiful scenery and invigorating trails.

Nightlife

Experience the vibrant nightlife at the Cairo VFW Post 5222, where you can enjoy live music and friendly conversation. For a laid-back evening, visit the local diner for classic American fare and a cozy atmosphere, perfect for unwinding after a day of exploration.

Booking tips and Expedia advantages for Cairo

To save money on your trip to Cairo, Illinois, consider visiting between November and January for lower accommodation rates, with Tuesday being the cheapest day to stay. Utilize Expedia to find budget-friendly options by sorting prices and filtering for Eco-certified hotels. Combine your hotel, flights, and activities for package savings, and join the One Key membership for exclusive discounts and cash rewards. Take advantage of free local attractions and use public transport for economical travel around the city to maximize your experience without overspending.

• The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Cairo are November to January, where the prices are slightly lower. This is in comparison to April to June, where prices are slightly higher.
• The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Cairo is Tuesday. The most expensive day to stay in Cairo is Saturday.
• Find cheap hotels on Expedia: Utilize Expedia’s search tool to tailor your options based on your budget, desired location, and hotel type. For instance, selecting the Eco-certified filter will showcase sustainable and environmentally-friendly hotels that are currently available. To find the best prices and offers, simply sort the price filter from lowest to highest.
• Consider bundling your trip: You can save money by combining your hotel stay in Cairo with your flights and activities through an Expedia package deal.
• Become a One Key member: Join Expedia's One Key membership program for exclusive discounts and deals on hotel bookings. You can also earn OneKeyCash to use on future selected hotels.

Find the best attractions in and around Cairo

Cairo, Illinois, is a great destination for outdoor enthusiasts and adventure seekers. Visitors can explore local attractions such as national parks, nature preserves, and historic forts. The area offers a blend of cultural experiences and scenic beauty, perfect for those looking to immerse themselves in nature or learn about the region's history. Don't miss out on a visit to Cairo itself to fully appreciate its charm and attractions.

• Fort Defiance State Park: This historic fort offers a glimpse into the past with its rich cultural vibes. Explore scenic trails and enjoy the views where the Mississippi and Ohio Rivers converge, making it a perfect spot for history buffs and nature lovers alike.
• Ballard Wildlife Management Area: Located 5 miles from Cairo, this preserve is a haven for wildlife enthusiasts. Experience its historical significance while enjoying budget-friendly outdoor activities like bird watching, hiking, and exploring diverse habitats.
• Columbus-Belmont State Park: Situated 17 miles away, this national park is an adventure seeker’s dream. With breathtaking scenery and plenty of outdoor activities like hiking, fishing, and picnicking, it promises a memorable experience in nature.

Best time to go to Cairo

The best time to visit Cairo is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are moderately low and weather is mostly sunny with light rain.

Calendar Month	Temperature	Precipitation	Cloudiness	Occupancy	Pricing
January	35.2°F (1.8°C)	Light Rain	Mostly Sunny	Moderately Low	Slightly Low
February	38.5°F (3.6°C)	Light Rain	Mostly Sunny	Moderately Low	Average
March	48.7°F (9.3°C)	Light Rain	Mostly Sunny	Moderately High	Average
April	57.7°F (14.3°C)	Light Rain	Mostly Sunny	Moderately High	Slightly High
May	67.5°F (19.7°C)	Light Rain	Mostly Sunny	Average	Slightly High
June	76.5°F (24.7°C)	Light Rain	Mostly Sunny	Average	Slightly High
July	79.0°F (26.1°C)	Light Rain	Mostly Sunny	Average	Average
August	77.2°F (25.1°C)	Light Rain	Mostly Sunny	Moderately High	Average
September	71.6°F (22.0°C)	Light Rain	Mostly Sunny	Average	Average
October	60.1°F (15.6°C)	Light Rain	Mostly Sunny	Average	Average
November	47.8°F (8.8°C)	Light Rain	Mostly Sunny	Moderately Low	Slightly Low
December	40.6°F (4.8°C)	Light Rain	Mostly Sunny	Average	Slightly Low

The nearest major airports for your trip to Cairo

Traveling to Cairo, Illinois, is convenient with several nearby airports. Paducah, KY (PAH-Barkley Regional), located 23 miles away, offers hotel options like The Respite Bed and Breakfast, Harrah's Metropolis Hotel & Casino, and The 1857. Marion, IL (MWA-Williamson County Regional) is 52 miles from Cairo, with hotels including Drury Inn & Suites Marion and Holiday Inn Express Hotel & Suites Marion Northeast. Cape Girardeau, MO (CGI-Cape Girardeau Municipal), 26 miles away, features Drury Plaza Hotel and Courtyard by Marriott Cape Girardeau Downtown. Each airport provides various transportation options to easily access your accommodations.