Find spa resorts & hotels in Downtown Rochester, Rochester from $117
Upfront pricing
Our total price for your stay includes taxes and fees
Treat yourself
Save 10% or more on over 100,000 hotels worldwide with Member Prices
Be picky
Search almost a million properties worldwide
Check availability on Downtown Rochester Resorts & Hotels with Spas
Check prices for these dates
Top Downtown Rochester Resorts & Hotels with Spas

Kahler Inn and Suites - Mayo Clinic Area
Kahler Inn and Suites - Mayo Clinic Area
7.8 out of 10, Good, (1368)
$112 nightly
The price is $130
Jul 25 - Jul 26
Total includes taxes and fees

Hotel Indigo Rochester – Mayo Clinic Area by IHG
Hotel Indigo Rochester – Mayo Clinic Area by IHG
8.8 out of 10, Excellent, (789)
$102 nightly
The price is $117
Aug 3 - Aug 4
Total includes taxes and fees

Hilton Rochester Mayo Clinic Area
Hilton Rochester Mayo Clinic Area
9.6 out of 10, Exceptional, (491)
$169 nightly
The price is $195
Jul 27 - Jul 28
Total includes taxes and fees

Hyatt House Rochester/Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
9.2 out of 10, Wonderful, (964)
$125 nightly
The price is $144
Jul 27 - Jul 28
Total includes taxes and fees

Marriott Rochester Mayo Clinic
Marriott Rochester Mayo Clinic
8.2 out of 10, Very Good, (506)
$199 nightly
The price is $229
Aug 8 - Aug 9
Total includes taxes and fees

Hilton Garden Inn Rochester Downtown, MN
Hilton Garden Inn Rochester Downtown, MN
8.8 out of 10, Excellent, (782)
$118 nightly
The price is $136
Jul 20 - Jul 21
Total includes taxes and fees

Broadway Plaza, Trademark Collection by Wyndham
Broadway Plaza, Trademark Collection by Wyndham
9.2 out of 10, Wonderful, (157)

Kahler Grand Hotel
Kahler Grand Hotel
8.2 out of 10, Very Good, (1444)
$114 nightly
The price is $132
Jul 19 - Jul 20
Total includes taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Recent reviews of Downtown Rochester hotels
Recent reviews of Downtown Rochester hotels
Recent reviews of Downtown Rochester hotelsExpedia verified reviews

Hotel Indigo Rochester – Mayo Clinic Area by IHG
5/5 Excellent
"Very nice rooms and staff. "
A verified traveler stayed at Hotel Indigo Rochester – Mayo Clinic Area by IHG
Posted 2 days ago
Frequently asked questions
Explore a world of travel with Expedia
Explore a world of travel with Expedia
- Hotels near Mayo Clinic
- Rochester Hotels
- Cheap Hotels in Rochester
- Luxury Hotels in Rochester
- Pet-friendly Hotels in Rochester
- Waterpark Hotels in Rochester
- Hotels with Free Airport Shuttle in Rochester
- Hotels with an Outdoor Pool in Rochester
- Hotels with an Indoor Pool in Rochester
- Hotels with Kitchenettes in Rochester
- Hotels with Hot Tubs in Rochester
- Hotels with Restaurants in Rochester
- Family Hotels in Rochester
- Boutique Hotels in Rochester
- Resorts & Hotels with Spas in Rochester
- Hotels with Bars in Rochester
- Hotels with Waterslides in Rochester
- Hotels with Balconies in Rochester
- Hotels with Free Breakfast in Rochester
- Hotels with a Pool in Rochester
- Hotels with Early Check-in in Rochester
- Hotels with Connecting Rooms in Rochester
- Hotel Wedding Venues Hotels in Rochester
- Honeymoon Resorts & in Rochester
- Romantic Hotels in Rochester
- Hotels with a Gym in Rochester
- Extended Stay Hotels in Rochester
- Hotels with a View in Rochester
- Historic Hotels in Rochester
- Hotels with Free Parking in Rochester
- Hotels with Suites in Rochester
- Hotels with Fireplaces in Rochester
- Golf Hotels in Rochester
- Hotels with Laundry Facilities in Rochester
- Hotels with Childcare in Rochester
- Hotels with Room Service in Rochester
- Hotel with a Concierge Hotels in Rochester
- Winery Hotels in Rochester
- Non-Smoking Hotels in Rochester
- Ski Hotels in Rochester
- Gay friendly Hotels in Rochester
- Quiet Resorts & in Rochester
- Hotels & Resorts for Couples in Rochester
- Hotels with Air Conditioning in Rochester
- Business Hotels in Rochester
- Motels in Rochester
- Best Western Hotels in Rochester
- Hotels near Shops University Square
- 5 Star Hotels in Rochester
- Apartments in Rochester
- Hotels near University of Minnesota-Rochester
- B&B in Rochester
- Cabin Rentals in Rochester
- Hotels near Mayo Civic Center
- Motel 6 Hotels in Rochester
- 3 Star Hotels in Rochester
- 4 Star Hotels in Rochester
- Aparthotels in Rochester
- Cottages in Rochester
- Americinn Hotels in Rochester
- Vacation Homes in Rochester
- Inns in Rochester
- Villas in Rochester
- Hotels near Rochester Art Center
- Hotels near Rochester Civic Theater
- Hotels near Mayo Park
- Hotels near Soldiers Field Veterans Memorial
- Hotels near Historic Southwest
- Hotels near Northrup
- Hotels near Soldiers Field Golf Course
- Hotels near Mayo Clinic Hospital - Saint Marys Campus
- Hotels near Silver Lake Park
- Car rentals near Rochester
- Car rentals near Mayo Clinic
- Enterprise Rental Cars in Rochester
- Car rentals in Avis 7412 West 159th Street
- Car rentals near University of Minnesota-Rochester
- Sportscar Car Rentals in Rochester
- Luxury Car Rentals in Rochester
- Hertz Rental Cars in Rochester
- Budget Rental Cars in Rochester
- Minivan Car Rentals in Rochester
- Convertible Car Rentals in Rochester
- Thrifty Car Rental Rental Cars in Rochester
- Payless Rental Cars in Rochester
- Car rentals near Mayo Clinic Hospital - Saint Marys Campus