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Compare 408 hotels close to Mayo Clinic with room rates, reviews, and availability. Most hotels are fully refundable.

Hilton Rochester Mayo Clinic Area
Lobby

Hilton Rochester Mayo Clinic Area

3.5 star property
9.6 out of 10, Exceptional, (491)
"Best stay in downtown Rochester in years. "
$169 nightly
The price is $195
Jul 27 - Jul 28
Total includes taxes and fees
Hilton Rochester Mayo Clinic Area
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Property amenity

TownePlace Suites by Marriott Rochester Mayo Clinic Area

3.0 star property
9.6 out of 10, Exceptional, (434)
"Wonderful hotel. Spacious, clean, close to the hospital. Will be staying there again! "
$109 nightly
The price is $125
Aug 8 - Aug 9
Total includes taxes and fees
TownePlace Suites by Marriott Rochester Mayo Clinic Area
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
View from property

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

2.5 star property
9.6 out of 10, Exceptional, (633)
"Clean, good service, decent breakfast. I would stay there again"
$98 nightly
The price is $113
Aug 3 - Aug 4
Total includes taxes and fees
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
The Berkman
Terrace/patio

The Berkman

3.0 star property
9.6 out of 10, Exceptional, (313)
"Great hotel."
$129 nightly
The price is $148
Jul 19 - Jul 20
Total includes taxes and fees
The Berkman
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Courtyard

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4.0 star property
9.4 out of 10, Exceptional, (847)
"The staff were friendly and so amazingly accommodating! "
$121 nightly
The price is $139
Jul 27 - Jul 28
Total includes taxes and fees
EVEN Hotel Rochester - Mayo Clinic Area by IHG
Hyatt House Rochester/Mayo Clinic Area
Terrace/patio

Hyatt House Rochester/Mayo Clinic Area

3.0 star property
9.2 out of 10, Wonderful, (964)
"The beds were extremely comfortable!"
$125 nightly
The price is $144
Jul 27 - Jul 28
Total includes taxes and fees
Hyatt House Rochester/Mayo Clinic Area
Home2 Suites by Hilton Rochester Mayo Clinic Area
Terrace/patio

Home2 Suites by Hilton Rochester Mayo Clinic Area

3.0 star property
9.6 out of 10, Exceptional, (816)
"Great place to stay when visiting Rochester. "
$121 nightly
The price is $139
Jul 20 - Jul 21
Total includes taxes and fees
Home2 Suites by Hilton Rochester Mayo Clinic Area
Residence Inn by Marriott Rochester Mayo Clinic Area South
BBQ/picnic area

Residence Inn by Marriott Rochester Mayo Clinic Area South

3.0 star property
9.6 out of 10, Exceptional, (180)
"Such a beautiful hotel. And the breakfast was amazing"
$118 nightly
The price is $136
Jul 20 - Jul 21
Total includes taxes and fees
Residence Inn by Marriott Rochester Mayo Clinic Area South
Staybridge Suites Rochester - Mayo Clinic Area by IHG
Courtyard

Staybridge Suites Rochester - Mayo Clinic Area by IHG

3.0 star property
9.4 out of 10, Exceptional, (375)
"Would definitely stay here again!"
$136 nightly
The price is $156
Jul 20 - Jul 21
Total includes taxes and fees
Staybridge Suites Rochester - Mayo Clinic Area by IHG
The Towers At Kahler Grand Hotel
Front of property

The Towers At Kahler Grand Hotel

4.0 star property
9.4 out of 10, Exceptional, (85)
"Great place to stay if going to Mayo. You don’t have to go outside to get to the buildings at Mayo with the subway level. Food is good for 2 meals a day. There’s room service & deliveries from Instacart if needed for groceries or outside food/beverage source. Personalized concierge service is good. Our stay was 10 days - they accommodated our extended stay flawlessly. My only complaint is the room temperature everywhere; it can be stuffy moving place to place. Take a fan to cool off in...
$356 nightly
The price is $410
Jul 22 - Jul 23
Total includes taxes and fees
The Towers At Kahler Grand Hotel
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
Terrace/patio

Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys

3.0 star property
9.2 out of 10, Wonderful, (428)
"Nice amenities, spacious, great breakfast options "
$110 nightly
The price is $126
Jul 20 - Jul 21
Total includes taxes and fees
Homewood Suites by Hilton Rochester Mayo Clinic Area / Saint Marys
Candlewood Suites Rochester Mayo Clinic Area by IHG
Exterior

Candlewood Suites Rochester Mayo Clinic Area by IHG

2.5 star property
9.4 out of 10, Exceptional, (435)
"Very clean, free parking, coffee shops nearby walking distance, great accommodations for the price. "
$101 nightly
The price is $116
Aug 8 - Aug 9
Total includes taxes and fees
Candlewood Suites Rochester Mayo Clinic Area by IHG
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Exterior

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 star property
8.8 out of 10, Excellent, (789)
"Very nice rooms and staff. "
$102 nightly
The price is $117
Aug 3 - Aug 4
Total includes taxes and fees
Hotel Indigo Rochester – Mayo Clinic Area by IHG
Hilton Garden Inn Rochester Downtown, MN
Breakfast served

Hilton Garden Inn Rochester Downtown, MN

3.0 star property
8.8 out of 10, Excellent, (782)
"Nice stay"
$118 nightly
The price is $136
Jul 20 - Jul 21
Total includes taxes and fees
Hilton Garden Inn Rochester Downtown, MN
Econo Lodge Mayo Clinic Area
Free daily full breakfast

Econo Lodge Mayo Clinic Area

2.0 star property
9.0 out of 10, Wonderful, (701)
"Exceptional value, very clean room, friendly staff, great location!"
$63 nightly
The price is $73
Jul 27 - Jul 28
Total includes taxes and fees
Econo Lodge Mayo Clinic Area
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Exterior

Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys

3.0 star property
9.0 out of 10, Wonderful, (723)
"Great location."
$123 nightly
The price is $142
Jul 20 - Jul 21
Total includes taxes and fees
Courtyard by Marriott Rochester Mayo Clinic Area/Saint Marys
Hampton Inn Rochester-South
Terrace/patio

Hampton Inn Rochester-South

2.5 star property
9.0 out of 10, Wonderful, (1004)
"Always a pleasure to stay here. "
$89 nightly
The price is $102
Aug 9 - Aug 10
Total includes taxes and fees
Hampton Inn Rochester-South
Brentwood Inn & Suites
Desk, iron/ironing board, free WiFi, bed sheets

Brentwood Inn & Suites

2.5 star property
8.6 out of 10, Excellent, (1003)
"I enjoyed my stay. Room was clean and the staff was helpful and friendly."
$125 nightly
The price is $144
Jul 15 - Jul 16
Total includes taxes and fees
Brentwood Inn & Suites
Quality Inn & Suites Mayo Clinic Area
Free daily full breakfast

Quality Inn & Suites Mayo Clinic Area

2.5 star property
8.8 out of 10, Excellent, (748)
"I stayed two night and when I called and need to extend my stay, they were very accommodating. Will definitely stay again. "
$67 nightly
The price is $77
Aug 10 - Aug 11
Total includes taxes and fees
Quality Inn & Suites Mayo Clinic Area
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
Exterior

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

3.0 star property
8.6 out of 10, Excellent, (817)
"Clean, quiet and friendly helpful staff. "
$96 nightly
The price is $111
Aug 8 - Aug 9
Total includes taxes and fees
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

What's the area like around Mayo Clinic?

Mayo Clinic is located in a welcoming area of Rochester known for its major shopping area. If you're looking for a convenient place to stay, check out the 150 hotels and other accommodations you'll find within a mile.

What's the best place to stay close to Mayo Clinic?

Adjacent to Mayo Clinic, Kahler Grand Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers 2 restaurants and an indoor pool. Other good options close by include Kahler Inn and Suites - Mayo Clinic Area and Hyatt House Rochester/Mayo Clinic Area.

How many hotels will I be able to find near Mayo Clinic?

Expedia has 150 hotels and other accommodations within a mile from Mayo Clinic.

If I need to cancel the hotel reservation for my stay near Mayo Clinic, will I receive a refund?

Yes, you'll find most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of your booking. Add your dates and click on "Search", then filter by "fully refundable" to get the best deals near Mayo Clinic.

Where can I learn more about changing or cancelling my trip in the area near Mayo Clinic?

For additional details about rescheduling or cancelling your stay near Mayo Clinic, head over to our customer service page.

What can I see and do near Mayo Clinic?

You'll want to browse the exhibits at Mayowood Mansion and History Center of Olmsted County. Learn about local history at Plummer House and Assisi Heights. You can enjoy live performances at Rochester Civic Theater and Marcus Rochester Cinema.