A calm lake with a small boat, a dock with colorful buildings, and a forested hill in the background.

Isla Grande Vacation Rentals

Check prices for these dates

In two weeks
Oct 9 - Oct 11
In two months
Nov 20 - Nov 22
In three months
Dec 18 - Dec 20
In four months
Jan 15 - Jan 17

Our top choices for Isla Grande vacation rentals

A beach with thatched-roof huts and palm trees.

1. Deluxe Beachfront 4-bedroom house in Colón Province

Deluxe Beachfront 4-bedroom house in Colón Province
Colón Province
$387 nightly
The price is $387
Sep 24 - Sep 25
Total with taxes and fees
Deluxe Beachfront 4-bedroom house in Colón Province
A modern house with a covered patio, a lawn, and a view of the surrounding landscape.

2. Lovely Caribbean Apartment with AC + Wifi + BBQ + Beach + Kitchen + Parking

Lovely Caribbean Apartment with AC + Wifi + BBQ + Beach + Kitchen + Parking
Puerto Lindo
$257 nightly
The price is $257
Sep 24 - Sep 25
Total with taxes and fees
Lovely Caribbean Apartment with AC + Wifi + BBQ + Beach + Kitchen + Parking
A covered outdoor dining area with a view of the beach and palm trees.

3. Caribbean getaway: beach cottage just on the sand

Caribbean getaway: beach cottage just on the sand
Palenque
9.0 out of 10, Wonderful, (4 reviews)
"the view is beautiful! We were taken care of well."
United States
Mirelys
$316 nightly
The price is $316
Sep 24 - Sep 25
Total with taxes and fees
Caribbean getaway: beach cottage just on the sand
A beach with three blue chairs facing the sea, a small hut in the distance, and a lush green island.

4. BEAUTIFUL APARTMENT IN FRONT OF THE SEA

BEAUTIFUL APARTMENT IN FRONT OF THE SEA
Portobelo
7.0 out of 10, Good, (4 reviews)
"All of it! Gabriel is a marvelous host; absolutely above and beyond. The house is lovely, very unique, and the location, right on the water, superb. We'll be back!"
United States
Rosa M.
$180 nightly
The price is $180
Sep 24 - Sep 25
Total with taxes and fees
BEAUTIFUL APARTMENT IN FRONT OF THE SEA
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Isla Grande Hotel Reviews

Ranchos de Chalia

Ranchos de Chalia

8/10 Good
"The hotel is a sleepy bed breakfast located close to the coast next to a tiny village. The property is older it could do a facelift. The single rooms are small, but functional. The air condition worked great. The pool was a big plus .The staff was very helpful and accommodating. My biggest concern was lack of communication when we tried via Expedia to get more information about directions and check-in. However, it worked ok in the end."
Otto 3-night trip
Posted 2 days ago
Ranchos de Chalia

Find out more about Isla Grande

Everything you need to know about Isla Grande vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Isla Grande vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Isla Grande vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Isla Grande vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Isla Grande. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Isla Grande in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $180 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Isla Grande rentals

At Expedia, we put the best Isla Grande vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Isla Grande rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Isla Grande vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Isla Grande. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find vacation rentals in Isla Grande?

Yes, we have vacation rentals near top sights in Isla Grande, or you can select a more secluded option if you'd like a relaxing place to stay. Isla Grande is known for its parks.

What are some of the best vacation home rentals in Isla Grande?

Deluxe Beachfront 4-bedroom house in Colón Province: This Isla Grande vacation home rental has air-conditioning and WiFi to help you feel perfectly comfortable in your new surroundings.

How many vacation rentals will I find in Isla Grande?

With 3 Expedia vacation rentals, you're sure to find just the right place for your Isla Grande stay.

What can I see and do in Isla Grande?

While you're exploring the area, Isla Mamey and Blanca Beach are a couple of picturesque spots to get outside and enjoy nature. In the larger area, you’ll find Playa La Angosta and Portobelo National Park.

What are vacation rentals like in Isla Grande?

Vacation rentals are private properties you can stay in for several days or more in Isla Grande. Vacation rentals offer extras such as laundry facilities and kitchens so you'll have everything you need. If you're concerned about a sanitized environment, vacation rentals can provide a sense of seclusion away from shared hotel elevators and busy concierge desks while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which makes a vacation rental an attractive choice for family gatherings.