Photo by Michele Butts

Find all hotels by Ayres Collection in La Mesa, CA from $160

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Compare rooms and suites by Ayres Collection in La Mesa with rates, reviews, and availability. Most hotels are fully refundable.

"Nice, clean and with very friendly staff"

$219 total

includes taxes & fees

May 27 - May 28

"I love everything no complaints 😁"

$173 total

includes taxes & fees

May 23 - May 24

Ayres Collection La Mesa Hotel Guide

Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Ayres Collection hotels in La Mesa, California. Known for well-appointed rooms and friendly, personalized service, each of the top Ayres Collection La Mesa hotels guarantees an unparalleled level of comfort and quality.

You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some La Mesa Ayres Collection locations may even offer extra little benefits and discounts for frequent travelers.

Recent reviews of La Mesa hotels
Expedia verified reviews

5/5 Excellent

"The staff was extremely courteous and friendly. This is an enjoyable location where you can have a great time with your family and feel free and safe. I highly recommend it. "

A verified traveler stayed at Paradise Point Resort & Spa

Posted 6 hours ago