La Mesa Vacations from $291

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Your La Mesa Vacation

Lock in a La Mesa vacation package that includes everything you need and nothing you don't. Good for gift and craft shops, dining and nightlife, think about staying in the neighborhood of Downtown San Diego. The Magnolia, Santee Lakes and Grossmont College are just a few of the attractions you'll want to explore during your trip to La Mesa. Browse Expedia's wide range of travel options and start organizing your perfect vacation to La Mesa today.

The Latest La Mesa vacation packages

Price found within the past 48 hours. Click for updated prices.
Outsite San Diego - Golden Hill

Outsite San Diego - Golden Hill

2 out of 5
Golden Hill
Save 100% on your flight
per person
Oct 4 - Oct 7
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8/10 Very Good! (10 reviews)
My room was so convenient from the front door, nice kitchen and washer and dryer. There was one guest that didn't like me,

Reviewed on Jul 5, 2025

Hyatt Vacation Club at The Welk, San Diego Area

Hyatt Vacation Club at The Welk, San Diego Area

3.5 out of 5
Lawrence Welk Resort Village
Save 100% on your flight
per person
Sep 27 - Oct 3
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8.2/10 Very Good! (1,310 reviews)
Staff was wonderful!

Reviewed on Jul 14, 2025

Sand Castle Inn

Sand Castle Inn

2.5 out of 5
Save 100% on your flight
per person
Sep 27 - Oct 3
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8.2/10 Very Good! (469 reviews)
Good location. Clean. New rooms. Good stuff. Recommended 100%. The best in this place

Reviewed on Jul 4, 2025

Barsala City Villas

Barsala City Villas

2.5 out of 5
Downtown San Diego
Save 100% on your flight
per person
Oct 4 - Oct 7
found 2 days ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
No reviews
Pala Casino Spa And Resort

Pala Casino Spa And Resort

4 out of 5
Save 100% on your flight
per person
Aug 29 - Sep 1
found 1 day ago
Roundtrip flight included
Denver (DEN) to San Diego (SAN)
8.8/10 Excellent! (3,521 reviews)
Really enjoyed my stay with friends and family. Sorry the pool closes so early.

Reviewed on Jul 14, 2025

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Discover the most popular places to visit in La Mesa

Mount Helix Park

5/5(1 review)

Learn about the local history of Casa de Oro-Mount Helix when you spend time at Mount Helix Park. Amble around this family-friendly area's waterfront or attend a sporting event.

Mount Helix Park

Computer Museum of America

You can spend an afternoon studying the exhibits at Computer Museum of America during your trip to La Mesa. Attend a sporting event while in this walkable area or simply enjoy the top-notch restaurants.

Computer Museum of America

What to do in La Mesa

LEGOLAND® California Resort

LEGOLAND® California Resort

$79
per adult
82% of travellers recommend
LEGOLAND® California Resort
San Diego City Lights Night Tour

San Diego City Lights Night Tour

$46
per adult
96% of travellers recommend
San Diego City Lights Night Tour
San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway

San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway

$124
per adult
86% of travellers recommend
San Diego Explorer Pass: Save up to 50 Percent - Includes USS Midway
See all activities in La Mesa

La Mesa Hotel Deals

Handlery Hotel
Handlery Hotel
3.5 out of 5
950 Hotel Cir N, San Diego, CA
$111 nightly
The price is $128 total per night from Jul 21 to Jul 22
$128 total
Jul 21 - Jul 22
Total includes taxes and fees
8/10 Very Good! (1,864 reviews)
"Nice experience"

Reviewed on Jul 12, 2025

Handlery Hotel
Wyndham San Diego Bayside
Wyndham San Diego Bayside
4 out of 5
1355 N Harbor Drive, San Diego, CA
$177 nightly
The price is $205 total per night from Jul 21 to Jul 22
$205 total
Jul 21 - Jul 22
Total includes taxes and fees
8.2/10 Very Good! (5,720 reviews)
"Great staff! The only thing was that our deadbolt didn’t work. Otherwise, it was great!"

Reviewed on Jul 13, 2025

Wyndham San Diego Bayside
Marriott Marquis San Diego Marina
Marriott Marquis San Diego Marina
4 out of 5
333 W Harbor Dr, San Diego, CA
$272 nightly
The price is $316 total per night from Aug 13 to Aug 14
$316 total
Aug 13 - Aug 14
Total includes taxes and fees
9/10 Wonderful! (1,741 reviews)
"Great location, served its purpose for the 4Th"

Reviewed on Jul 11, 2025

Marriott Marquis San Diego Marina
See all 8,037 properties in La Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best La Mesa Vacation Packages

La Mesa Essential Information

Language
English
Currency
U.S dollars
Closest Airport
San Diego Intl. Airport (SAN)
Population
60,100
Max Temp Winter
65ºF
Max Temp Summer
80ºF
Top Sights
San Diego Zoo, Coronado Beach and Old Town San Diego State Park

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Frequently asked questions

How much does a La Mesa vacation package cost?
Offering great value package deals from $291 on Expedia, you'll be pleasantly surprised at how much a vacation to La Mesa costs! Expedia's packages make travel planning easier and save you more.
What are the cheapest months to go to La Mesa?
January, October and December are the best times to search for cheap La Mesa vacation packages. Opting to travel in quieter months means you can typically find lower prices on flights and hotels.
How many days is enough for La Mesa?
Usually, a handful of days is enough to visit the major attractions during your La Mesa vacation. However, if you prefer to have some time to chill out or go on day trips, think about extending your trip.
Is it worth booking a vacation package to La Mesa?
It's no wonder a La Mesa vacation is on the to-do list of many travelers. Well-known attractions like Mount Helix Park are just the beginning of things to keep you busy here.
How to find the best La Mesa package deals?
Use Expedia's filters to help you find some fabulous La Mesa package deals. When you start your search, just set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your adventure for midweek, or look for La Mesa package deals in the low season. Switch up your travel dates and you may land even bigger discounts. As a rule of thumb, it's usually best to book your vacation package well in advance.
Is it cheaper to book a La Mesa vacation as a package?
Expedia vacation packages are designed to give you more bang for your buck. Bundle your flight, hotel and car rental into one great-value price and enjoy significant savings. You'll usually score a better deal than booking each component individually. And you'll still get the freedom to create a personalized La Mesa vacation by choosing your favorite type of stay, airline and car class.
When to book a vacation package to La Mesa?
Secure fantastic discounts by reserving your flights in advance with Expedia. If being spontaneous is more your style, take advantage of our last-minute deals for an impromptu La Mesa adventure.
How to plan a trip to La Mesa?

  1. Pick your travel dates: What you plan to do in La Mesa and your favorite season will help you decide when to get away.
  2. Set your budget: Factor in expenses like food, flights and transportation when calculating how much to set aside for your trip to La Mesa. Then, choose a property that matches your budget, whether that's a low-cost stay or a more upscale getaway.
  3. Discover La Mesa using Expedia's trip planning tool: Gain insights into the most popular attractions and best properties for your trip to La Mesa. You can also save your must-visit places, collaborate with family and friends and organize all your plans in one place.
  4. Work out your trip length: Consider how long you'd like to spend exploring La Mesa. Plan your days so you can get to all the activities and attractions you're interested in without rushing.
  5. Bundle your accommodations and airfare: Once you've nailed down your trip dates and duration, book the right La Mesa vacation package for you.
  6. Book activities and experiences ahead of time: Whether it's entrance to a major attraction or a day trip in nature, you won't have to worry about missing out on the best La Mesa has to offer. Find all the incredible things to do in La Mesa with our dedicated activity guide.

Does Expedia offer Book Now, Pay Later La Mesa vacation packages?
If you're like us, you love going away but don't love the big price tag that can sometimes come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the total cost of your La Mesa vacation over 3, 6 or 12 months. There are also no hidden costs or late payment fees, so you can secure great vacation packages with payment plans as soon as you see them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.