Title: La Serena Vacation Rentals from $67: Search Short-Term Rentals | Expedia.com

[La Serena Travel Guide](https://expedia.com/La-Serena.dx2139)[Hotels in La Serena](https://expedia.com/La-Serena-Hotels.d2139.Travel-Guide-Hotels)[Flights to La Serena](https://expedia.com/Cheap-Flights-To-La-Serena.d2139.Travel-Guide-Flights)[Things to do in La Serena](https://expedia.com/Things-To-Do-In-La-Serena.d2139.Travel-Guide-Activities)[Car Rentals in La Serena](https://expedia.com/Car-Rentals-In-La-Serena.d2139.Car-Rental-Guide)[La Serena Vacation Packages](https://expedia.com/La-Serena.d2139.Destination-Travel-Guides)

![Lighthouse at La Serena, Chile](https://images.trvl-media.com/place/2139/d4916bcd-6a4a-4c25-b665-93e13c32c0c5.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/2139/d4916bcd-6a4a-4c25-b665-93e13c32c0c5.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=2139&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[May 22 - May 24](https://www.expedia.com/Hotel-Search?regionId=2139&startDate=2026-05-22&endDate=2026-05-24&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[Jun 19 - Jun 21](https://www.expedia.com/Hotel-Search?regionId=2139&startDate=2026-06-19&endDate=2026-06-21&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jul 17 - Jul 19](https://www.expedia.com/Hotel-Search?regionId=2139&startDate=2026-07-17&endDate=2026-07-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for La Serena vacation rentals

![3 outdoor pools, open 11:00 AM to 8:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/105000000/104290000/104287600/104287525/578aa723.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/105000000/104290000/104287600/104287525/f5bcd040.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Classic Cabin (Cabaña para 1 a 2 personas) | Premium bedding, down comforters, in-room safe, blackout drapes](https://images.trvl-media.com/lodging/105000000/104290000/104287600/104287525/3757d586.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/105000000/104290000/104287600/104287525/dac6a47a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabaña Villa Los Plátanos

[](https://www.expedia.com/La-Serena-Hotels-Cabana-Villa-Los-Platanos.h104287525.Hotel-Information)

La Serena

10/10

Exceptional

(2 reviews)

$67 nightly

$67 total

Mar 25 - Mar 26

[](https://www.expedia.com/La-Serena-Hotels-Cabana-Villa-Los-Platanos.h104287525.Hotel-Information)

![In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/108000000/107020000/107013800/107013715/84c860a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/108000000/107020000/107013800/107013715/8d5a7f19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Departamento 06 | Private kitchen | Fridge, oven, electric kettle, toaster](https://images.trvl-media.com/lodging/108000000/107020000/107013800/107013715/3a66e21a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Departamento 06 | Bathroom | Combined shower/tub, rainfall showerhead, hair dryer, towels](https://images.trvl-media.com/lodging/108000000/107020000/107013800/107013715/3300cb3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### ELDEPTO LA SERENA

[](https://www.expedia.com/Coquimbo-Hotels-ELDEPTO-LA-SERENA.h107013715.Hotel-Information)

Coquimbo

8.0/10

Very Good

(2 reviews)

"Boa localização de fácil acesso, tranquilidade e bom atendimento"

![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg)

Ricardo Horacio

$50 nightly

$50 total

Mar 25 - Mar 26

[](https://www.expedia.com/Coquimbo-Hotels-ELDEPTO-LA-SERENA.h107013715.Hotel-Information)

![Business center](https://images.trvl-media.com/lodging/21000000/20070000/20066100/20066075/e8460db3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Honeymoon Apartment, 1 Queen Bed, Accessible, Beachfront | Terrace/patio](https://images.trvl-media.com/lodging/21000000/20070000/20066100/20066075/83e753f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, 2 Bedrooms, Ocean View, Beachside | In-room dining](https://images.trvl-media.com/lodging/21000000/20070000/20066100/20066075/33710e4f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Honeymoon Apartment, 1 Queen Bed, Accessible, Beachfront | Living room | 49-inch flat-screen TV with cable channels, Smart TV](https://images.trvl-media.com/lodging/21000000/20070000/20066100/20066075/82544b38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Choza VIP Turquesa en La Serena

[](https://www.expedia.com/La-Serena-Hotels-La-Choza-VIP-Turquesa-En-La-Serena.h20066075.Hotel-Information)

Coquimbo

7.6/10

Good

(11 reviews)

"The apartment was very good for my needs and close to the conference centre. Safe, clean, well appointed. Yanitza was a big help and responsive to WhatsApp messages."

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Andrew

[](https://www.expedia.com/La-Serena-Hotels-La-Choza-VIP-Turquesa-En-La-Serena.h20066075.Hotel-Information)

![32-inch flat-screen TV with cable channels, first-run movies](https://images.trvl-media.com/lodging/88000000/87730000/87728000/87727948/3cd1e7d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Classic Double or Twin Room | Living area | 32-inch flat-screen TV with cable channels, first-run movies](https://images.trvl-media.com/lodging/88000000/87730000/87728000/87727948/26ad5929.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/88000000/87730000/87728000/87727948/682833ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/88000000/87730000/87728000/87727948/ca60aef8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Domos Dream hotel cabañas

[](https://www.expedia.com/La-Serena-Hotels-Domos-Dream-Hotel-Cabanas.h87727948.Hotel-Information)

La Serena

8.6/10

Excellent

(4 reviews)

"It was far away."

![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg)

Sergio

$81 nightly

$81 total

Mar 25 - Mar 26

[](https://www.expedia.com/La-Serena-Hotels-Domos-Dream-Hotel-Cabanas.h87727948.Hotel-Information)

![Garden](https://images.trvl-media.com/lodging/9000000/8060000/8057300/8057286/19dd421c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/9000000/8060000/8057300/8057286/ff30d372.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Apartment | View from room](https://images.trvl-media.com/lodging/9000000/8060000/8057300/8057286/b486105f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/9000000/8060000/8057300/8057286/3e664569.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apart Hotel y Cabañas Vegasur

[](https://www.expedia.com/La-Serena-Hotels-Apart-Hotel-Y-Cabanas-Vegasur.h8057286.Hotel-Information)

La Serena

8.6/10

Excellent

(95 reviews)

"LIMPIEZA BUENA, NO TENGO REPAROS AL RESPECTO."

![Chile](https://a.travel-assets.com/egds/marks/flags/cl.svg)

Martin

[](https://www.expedia.com/La-Serena-Hotels-Apart-Hotel-Y-Cabanas-Vegasur.h8057286.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/112000000/111450000/111440900/111440895/6a3317ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/112000000/111450000/111440900/111440895/5b10fbff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Room | 2 bedrooms, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/112000000/111450000/111440900/111440895/acf8d706.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Garden](https://images.trvl-media.com/lodging/112000000/111450000/111440900/111440895/19578f2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabañas Yunkai

[](https://www.expedia.com/Vicuna-Hotels-Cabanas-Yunkai.h111440895.Hotel-Information)

Vicuña

$77 nightly

$77 total

Mar 28 - Mar 29

[](https://www.expedia.com/Vicuna-Hotels-Cabanas-Yunkai.h111440895.Hotel-Information)

![Beach massages](https://images.trvl-media.com/lodging/26000000/25840000/25836900/25836876/d9d1bf94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Apartment, 3 Bedrooms, Non Smoking, City View | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/26000000/25840000/25836900/25836876/b39f32f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Apartment, 3 Bedrooms, Non Smoking | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/26000000/25840000/25836900/25836876/373f876a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Apartment, 3 Bedrooms, Non Smoking | Egyptian cotton sheets, premium bedding, memory foam beds](https://images.trvl-media.com/lodging/26000000/25840000/25836900/25836876/08998581.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cosmopolita

[](https://www.expedia.com/La-Serena-Hotels-Cosmopolita.h25836876.Hotel-Information)

La Serena

10/10

Exceptional

(2 reviews)

"Highly recommend! The apartment was great and comfortable with everything you need and in a great location, and the owner Yanitza is incredibly nice and helpful and can tell you many things to do and see and is a very friendly person who makes you feel welcome."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

brett

[](https://www.expedia.com/La-Serena-Hotels-Cosmopolita.h25836876.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/104000000/103130000/103124200/103124138/7815e33b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/104000000/103130000/103124200/103124138/a4a4c864.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/104000000/103130000/103124200/103124138/ac9139f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/104000000/103130000/103124200/103124138/c92589ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Elqui Valley Avocado Farm, 2-bedroom cabin in fabulous Vicuña with WiFi

[](https://www.expedia.com/Vicuna-Hotels-Elqui-Valley-Avocado-Farm.h103124138.Hotel-Information)

Vicuña

$150 nightly

$150 total

Apr 13 - Apr 14

[](https://www.expedia.com/Vicuna-Hotels-Elqui-Valley-Avocado-Farm.h103124138.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/117000000/116480000/116472400/116472356/c428ca47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Oven](https://images.trvl-media.com/lodging/117000000/116480000/116472400/116472356/c1e397f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/117000000/116480000/116472400/116472356/09bfc77e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/117000000/116480000/116472400/116472356/28f96dd0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Comfortable apartment In coquimbo with parking space

[](https://www.expedia.com/Coquimbo-Hotels-Comfortable-Apartment-In-Coquimbo-With-Parking-Space.h116472356.Hotel-Information)

Coquimbo

$73 nightly

$73 total

Mar 26 - Mar 27

[](https://www.expedia.com/Coquimbo-Hotels-Comfortable-Apartment-In-Coquimbo-With-Parking-Space.h116472356.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/38000000/37630000/37622600/37622526/9a70966a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/38000000/37630000/37622600/37622526/21510064.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/38000000/37630000/37622600/37622526/187df6c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, in-room safe, iron/ironing board, WiFi](https://images.trvl-media.com/lodging/38000000/37630000/37622600/37622526/b04c9bb9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 2nd Floor WiFi La Serena Beach & Casino!

[](https://www.expedia.com/Coquimbo-Hotels-2nd-Floor-WiFi-La-Serena-Beach-Casino.h37622526.Hotel-Information)

Coquimbo

10/10

Exceptional

(1 review)

"Excelente departamento, ubicación y comodidad, muchas gracias Yanitza por todo!!! Esperamos volver pronto!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Daniela

$143 nightly

$143 total

Mar 25 - Mar 26

[](https://www.expedia.com/Coquimbo-Hotels-2nd-Floor-WiFi-La-Serena-Beach-Casino.h37622526.Hotel-Information)

![1 bedroom](https://images.trvl-media.com/lodging/37000000/36350000/36344400/36344347/bc839c97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/37000000/36350000/36344400/36344347/e2dd4715.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hair dryer, towels, toilet paper](https://images.trvl-media.com/lodging/37000000/36350000/36344400/36344347/06afea6a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![](https://images.trvl-media.com/lodging/37000000/36350000/36344400/36344347/cda1ea8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Loft, the Horseshoe 02 passengers

[](https://www.expedia.com/Coquimbo-Hotels-Loft.h36344347.Hotel-Information)

coquimbo

$59 nightly

$59 total

Mar 26 - Mar 27

[](https://www.expedia.com/Coquimbo-Hotels-Loft.h36344347.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/78000000/77070000/77064300/77064270/630b114c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, oven, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/78000000/77070000/77064300/77064270/cf6506a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/78000000/77070000/77064300/77064270/7626f621.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Onsite parking](https://images.trvl-media.com/lodging/78000000/77070000/77064300/77064270/5655ceb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Enjoy Coquimbo Apartment one block away

[](https://www.expedia.com/Coquimbo-Hotels-Enjoy-Coquimbo-Apartment-One-Block-Away.h77064270.Hotel-Information)

coquimbo

$160 nightly

$184 total

Mar 26 - Mar 27

[](https://www.expedia.com/Coquimbo-Hotels-Enjoy-Coquimbo-Apartment-One-Block-Away.h77064270.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/121000000/120900000/120897300/120897204/11ff680b_edited_b162.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/121000000/120900000/120897300/120897204/de5d34bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/121000000/120900000/120897300/120897204/w1308h993x0y1-348c83be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/121000000/120900000/120897300/120897204/w1308h993x0y1-e623b8ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Elegant apartment in a privileged location in the heart of Avenida del Mar.

[](https://www.expedia.com/La-Serena-Hotels-Vrbo-Property.h120897204.Hotel-Information)

La Serena

8.0/10

Very Good

(1 review)

"The building is nice because it is conveniently located near the beach and lots of shops and restaurants. It was easy to locate the tower and room we rented. The rooms were clean, but the apartment and all bedding smelled of smoke. I am not a smoker so this was unexpected and disappointing. Also, the noise level is quit high because the walls are very thin."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Elena

$153 nightly

$153 total

Mar 26 - Mar 27

[](https://www.expedia.com/La-Serena-Hotels-Vrbo-Property.h120897204.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/115000000/114600000/114596200/114596164/w1080h807x0y7-2b3e7135.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, oven, dishwasher, electric kettle](https://images.trvl-media.com/lodging/115000000/114600000/114596200/114596164/w1080h810x0y5-b0bf4b8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/115000000/114600000/114596200/114596164/w1080h804x0y0-a73ff1be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Microwave, oven, dishwasher, electric kettle](https://images.trvl-media.com/lodging/115000000/114600000/114596200/114596164/e300dafb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Beach, breezes and sea Beautiful and comfortable apartment with exceptional location.

[](https://www.expedia.com/Coquimbo-Hotels-Beach.h114596164.Hotel-Information)

Coquimbo

$92 nightly

$101 total

Mar 25 - Mar 26

[](https://www.expedia.com/Coquimbo-Hotels-Beach.h114596164.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/80000000/79130000/79128800/79128717/de2bdd52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![TV, stereo](https://images.trvl-media.com/lodging/80000000/79130000/79128800/79128717/1dc5fef3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/80000000/79130000/79128800/79128717/5f596ecc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool](https://images.trvl-media.com/lodging/80000000/79130000/79128800/79128717/4f881c78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### "Nicoland" Playa, piscina, La Serena

[](https://www.expedia.com/La-Serena-Hotels-Nicoland-Playa.h79128717.Hotel-Information)

La Serena

10/10

Exceptional

(1 review)

"Hermoso departamento,muy bien amoblado, no le falta nada. Excelente ubicación. Queremos destacar la atención de la anfitriona Yanitza, quien siempre estuvo atenta a todas nuestras necesidades y consultas. De seguro volveremos!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Daniela

$140 nightly

$140 total

Mar 25 - Mar 26

[](https://www.expedia.com/La-Serena-Hotels-Nicoland-Playa.h79128717.Hotel-Information)

![Classic Apartment, Ocean View | Living area](https://images.trvl-media.com/lodging/113000000/112740000/112736400/112736365/a3662af1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Classic Apartment, Ocean View | Private kitchen](https://images.trvl-media.com/lodging/113000000/112740000/112736400/112736365/1b824154.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Classic Apartment, Ocean View | Private kitchen](https://images.trvl-media.com/lodging/113000000/112740000/112736400/112736365/d14df2f3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Classic Apartment, Ocean View | 3 bedrooms, free WiFi](https://images.trvl-media.com/lodging/113000000/112740000/112736400/112736365/90be6355.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Depto Serena Golf

[](https://www.expedia.com/La-Serena-Hotels-Depto-Serena-Golf.h112736365.Hotel-Information)

La Serena

$289 nightly

$289 total

Apr 8 - Apr 9

[](https://www.expedia.com/La-Serena-Hotels-Depto-Serena-Golf.h112736365.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/103000000/102230000/102222800/102222748/8ed7542e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/103000000/102230000/102222800/102222748/2557ace0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/103000000/102230000/102222800/102222748/5c670165.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/103000000/102230000/102222800/102222748/e4cc8ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cozy Self-sustainable Cabin with beautiful views of the Elqui Valley,Pet Friend

[](https://www.expedia.com/La-Serena-Hotels-Cozy-Self-Sustainable-Cabin-With-Beautiful-Views-Of-The-Elqui-Valley.h102222748.Hotel-Information)

La Serena

$83 nightly

$83 total

Mar 25 - Mar 26

[](https://www.expedia.com/La-Serena-Hotels-Cozy-Self-Sustainable-Cabin-With-Beautiful-Views-Of-The-Elqui-Valley.h102222748.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/106000000/105770000/105769300/105769295/9327bcce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/106000000/105770000/105769300/105769295/e3930909.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/106000000/105770000/105769300/105769295/6338524d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/106000000/105770000/105769300/105769295/2d21f2f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Beautiful & unique beach apartament in the oldest bay and coastal city of Chile 

[](https://www.expedia.com/La-Serena-Hotels-Beautiful-Unique-Beach-Apartament-In-The-Oldest-Bay-And-Coastal-City-Of-Chile.h105769295.Hotel-Information)

La Serena

$110 nightly

$110 total

Mar 25 - Mar 26

[](https://www.expedia.com/La-Serena-Hotels-Beautiful-Unique-Beach-Apartament-In-The-Oldest-Bay-And-Coastal-City-Of-Chile.h105769295.Hotel-Information)

![Property grounds](https://images.trvl-media.com/lodging/102000000/101440000/101430800/101430739/85a38ab7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/102000000/101440000/101430800/101430739/fd9c6531.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/102000000/101440000/101430800/101430739/868e092f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/102000000/101440000/101430800/101430739/14ea8a37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hermoso Departamento, Ideal Para Escapadas, a 15 Minutos de la Playa

[](https://www.expedia.com/Coquimbo-Hotels-Hermoso-Departamento.h101430739.Hotel-Information)

Coquimbo

$70 nightly

$70 total

Mar 25 - Mar 26

[](https://www.expedia.com/Coquimbo-Hotels-Hermoso-Departamento.h101430739.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/50000000/49240000/49238500/49238439/7c4c2aca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/50000000/49240000/49238500/49238439/353dd86a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/50000000/49240000/49238500/49238439/2bcd88a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![](https://images.trvl-media.com/lodging/50000000/49240000/49238500/49238439/32bfcf38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cómoda Casa Ubicada en un lindo sector y muy tranquilo, ceca de supermercados.

[](https://www.expedia.com/Coquimbo-Hotels-Comoda-Casa-Ubicada-En-Un-Lindo-Sector-Y-Muy-Tranquilo.h49238439.Hotel-Information)

Coquimbo

$170 nightly

$170 total

Mar 25 - Mar 26

[](https://www.expedia.com/Coquimbo-Hotels-Comoda-Casa-Ubicada-En-Un-Lindo-Sector-Y-Muy-Tranquilo.h49238439.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-07&endDate=2026-04-08&regionId=2139&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

## Find vacation rentals that suit your style

Apartments

[](https://www.expedia.com/Hotel-Search?destination=La+Serena%2C+Coquimbo+Region%2C+Chile&regionId=2139&latLong=-29.90267%2C-71.251938&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=APARTMENT)

Aparthotels

[](https://www.expedia.com/Hotel-Search?destination=La+Serena%2C+Coquimbo+Region%2C+Chile&regionId=2139&latLong=-29.90267%2C-71.251938&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=APART_HOTEL)

Private vacation homes

[](https://www.expedia.com/Hotel-Search?destination=La+Serena%2C+Coquimbo+Region%2C+Chile&regionId=2139&latLong=-29.90267%2C-71.251938&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=VACATION_HOME)

Cabins

[](https://www.expedia.com/Hotel-Search?destination=La+Serena%2C+Coquimbo+Region%2C+Chile&regionId=2139&latLong=-29.90267%2C-71.251938&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=CABIN)

Cottages

[](https://www.expedia.com/Hotel-Search?destination=La+Serena%2C+Coquimbo+Region%2C+Chile&regionId=2139&latLong=-29.90267%2C-71.251938&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=COTTAGE)

Condos

[](https://www.expedia.com/Hotel-Search?destination=La+Serena%2C+Coquimbo+Region%2C+Chile&regionId=2139&latLong=-29.90267%2C-71.251938&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=CONDO)

Chalets

[](https://www.expedia.com/Hotel-Search?destination=La+Serena%2C+Coquimbo+Region%2C+Chile&regionId=2139&latLong=-29.90267%2C-71.251938&adults=2&startDate=2026-06-22&d1=2026-06-22&endDate=2026-06-25&d2=2026-06-25&lodging=CHALET)

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## Top La Serena Hotel Reviews

![Hotel Canto del Mar](https://images.trvl-media.com/lodging/113000000/112970000/112966800/112966711/047ed19f_y.jpg)

### Hotel Canto del Mar

4/10 Poor

"Below average as is not only outdated but smelly. We had 2 rooms and one could not be used to shower as the place was poorly designed and the shower water run out of the bathroom towards the room’s floor. there was no bath/edge to contain the water in the shower area. There are weird steps inside the room, catching my toes every time I walked to the toilet. There were drilling noises coming from next door at midnight. The staff said there was nothing they could do. Didn’t even offer to change rooms. I’ll be back next week to town but cannot stay there again. Too many options in the area to bother with bad service and facilities again. "

[](https://expedia.com/La-Serena-Hotels-Hotel-Canto-Del-Mar.h112966711.Hotel-Information)

![Primera Hacienda Hotel Boutique](https://images.trvl-media.com/lodging/14000000/13360000/13357200/13357169/46bfad8b_y.jpg)

### Primera Hacienda Hotel Boutique

10/10 Excellent

"This hotel is just beautiful. Maria is an amazing and caring host in her fourth generation Chilean home. It’s beautiful. Tasteful rooms and and a lovely rustic homely feel to it. Would highly recommend. "

[](https://expedia.com/La-Serena-Hotels-Primera-Hacienda-Hotel-Boutique.h13357169.Hotel-Information)

![Hostal La Serena](https://images.trvl-media.com/lodging/42000000/41510000/41509600/41509532/ba4c6d63_y.jpg)

### Hostal La Serena

10/10 Excellent

"El desayuno es muy completo y rico, muy amable el trato de Katy y de don Marcelo. "

[](https://expedia.com/La-Serena-Hotels-Hostal-La-Serena.h41509532.Hotel-Information)

![Hotel Club La Serena](https://images.trvl-media.com/lodging/1000000/430000/428300/428299/55b3bab7_y.jpg)

### Hotel Club La Serena

10/10 Excellent

"Excellent location!"

[](https://expedia.com/La-Serena-Hotels-Hotel-Club-La-Serena.h428299.Hotel-Information)

![Hotel Costa Real](https://images.trvl-media.com/lodging/28000000/27180000/27173400/27173320/88de3f01_y.jpg)

### Hotel Costa Real

10/10 Excellent

"Clean and the staff was excellent Will definitely come back "

[](https://expedia.com/La-Serena-Hotels-Hotel-Costa-Real.h27173320.Hotel-Information)

![Aji Verde Hostel](https://images.trvl-media.com/lodging/22000000/22000000/21992300/21992256/5813347a_y.jpg)

### Aji Verde Hostel

4/10 Poor

"The hostel is located near the market, which makes the area feel unsafe at night. The staff and volunteers were inattentive. The rooms are very dark and overcrowded with too many beds, leaving little space to move around or store luggage. There is only a small window, which doesn’t provide enough natural light or ventilation. Although there are a few seating areas, they feel cramped and are furnished with unattractive furniture. I do not recommend this hostel."

[](https://expedia.com/La-Serena-Hotels-Aji-Verde-Hostel.h21992256.Hotel-Information)

![Hotel Chagual](https://images.trvl-media.com/lodging/25000000/24220000/24214200/24214154/f5815869_y.jpg)

### Hotel Chagual

4/10 Poor

"More a Hostel, that an boutique hotel "

[](https://expedia.com/La-Serena-Hotels-Hotel-Chagual.h24214154.Hotel-Information)

![Hotel Diego de Almagro La Serena Express](https://images.trvl-media.com/lodging/111000000/110440000/110439900/110439848/5ac899a7_y.jpg)

### Hotel Diego de Almagro La Serena Express

8/10 Good

"Room quality was very good and the room was very clean every day,"

[](https://expedia.com/La-Serena-Hotels-Hotel-Diego-De-Almagro-La-Serena-Express.h110439848.Hotel-Information)

![Cabañas MarSerena](https://images.trvl-media.com/lodging/16000000/15370000/15362400/15362350/8fee7851_y.jpg)

### Cabañas MarSerena

10/10 Excellent

"very nice place to stay close to the beach, reasonably price and everybody there was very very pleasant"

[](https://expedia.com/La-Serena-Hotels-Cabanas-MarSerena.h15362350.Hotel-Information)

## Find out more about La Serena

**Everything you need to know about La Serena vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the La Serena vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect La Serena vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**La Serena vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in La Serena. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit La Serena in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $67 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on La Serena rentals**

At Expedia, we put the best La Serena vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top La Serena rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream La Serena vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around La Serena. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

## Explore a world of travel with Expedia

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- [Clearwater Beach Vacation Rentals ](https://www.expedia.com/Clearwater-Beach-Vacation-Rentals.d10759.Travel-Guide-VacationRentals)
- [Palm Springs Vacation Rentals ](https://www.expedia.com/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals)
- [Florida Keys Vacation Rentals ](https://www.expedia.com/Florida-Keys-Vacation-Rentals.d6023765.Travel-Guide-VacationRentals)
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- [Lake of the Ozarks Vacation Rentals ](https://www.expedia.com/Lake-Ozark-Vacation-Rentals.d177772.Travel-Guide-VacationRentals)
- [Florida Vacation Rentals ](https://www.expedia.com/Destinations-In-Florida.d211.Vacation-Rental-Destinations)
- [Hawaii Vacation Rentals ](https://www.expedia.com/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations)
- [Michigan Vacation Rentals ](https://www.expedia.com/Destinations-In-Michigan.d224.Vacation-Rental-Destinations)

- [Apartments in La Serena ](https://expedia.com/La-Serena-Apartments.d2139-aaApartments.Travel-Guide-Accommodation)
- [Cottages in La Serena ](https://expedia.com/La-Serena-Cottages.d2139-aaCottages.Travel-Guide-Accommodation)
- [Cabin Rentals in La Serena ](https://expedia.com/La-Serena-Cabins.d2139-aaCabins.Travel-Guide-Accommodation)
- [Hostels in La Serena ](https://expedia.com/La-Serena-Hostels.d2139-aaHostels.Travel-Guide-Accommodation)
- [Aparthotels in La Serena ](https://expedia.com/La-Serena-Apart-Hotels.d2139-aaApartHotels.Travel-Guide-Accommodation)
- [B&B in La Serena ](https://expedia.com/La-Serena-Bed-And-Breakfast.d2139-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Villas in La Serena ](https://expedia.com/La-Serena-Villas.d2139-aaVillas.Travel-Guide-Accommodation)

## Frequently asked questions

### Can I find a vacation rental in La Serena?

### What are some of the best vacation rentals in La Serena?

### How many vacation rentals will I find in La Serena?

### What can I see and do in La Serena?

### What are vacation rentals like in La Serena?

### Expedia's Latest Trends

Hotels

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- [Hotel Rooms in Andacollo](https://expedia.com/Andacollo-Hotels.d6203778.Travel-Guide-Hotels)

Flights

- [Flights to PUQ](https://expedia.com/Cheap-Flights-To-Torres-Del-Paine.d6127101.Travel-Guide-Flights)
- [Flights to PUQ](https://expedia.com/Cheap-Flights-To-Punta-Arenas.d2904.Travel-Guide-Flights)
- [Flights to CJC](https://expedia.com/Cheap-Flights-To-San-Pedro-De-Atacama.d500224.Travel-Guide-Flights)
- [Flights to ANF](https://expedia.com/Cheap-Flights-To-Antofagasta.d382.Travel-Guide-Flights)
- [Flights to CCP](https://expedia.com/Cheap-Flights-To-Los-Angeles.d500226.Travel-Guide-Flights)
- [Flights to VAP](https://expedia.com/Cheap-Flights-To-Cartagena.d6236111.Travel-Guide-Flights)

Cars

- [Car rentals in San Pedro de Atacama](https://expedia.com/Car-Rentals-In-San-Pedro-De-Atacama.d500224.Car-Rental-Guide)
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- [Car rental La Serena Airport (LSC)](https://expedia.com/Car-Rentals-In-La-Florida.d6029785.Car-Rental-Guide)

Activities

- [Things to do in San Antonio](https://expedia.com/Things-To-Do-In-San-Antonio.d6336623.Travel-Guide-Activities)
- [Things to do in Valparaiso](https://expedia.com/Things-To-Do-In-Valparaiso.d602827.Travel-Guide-Activities)
- [Things to do in Coquimbo](https://expedia.com/Things-To-Do-In-Coquimbo.d6024027.Travel-Guide-Activities)
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Packages

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- [Mall Plaza La Serena](https://expedia.com/Mall-Plaza-La-Serena-La-Serena.d6311978.Vacation-Attraction)
- [Observatorio Turístico Collowara](https://expedia.com/Observatorio-Turistico-Collowara-La-Serena.d553248621532374491.Vacation-Attraction)

General

- [Visit Concepción](https://expedia.com/Concepcion.dx790)
- [Visit Valparaiso](https://expedia.com/Valparaiso.dx602827)
- [Visit Vina del Mar](https://expedia.com/Vina-Del-Mar.dx6053651)
- [Visit Los Andes](https://expedia.com/Los-Andes.dx6272982)
- [Visit Hanga Roa](https://expedia.com/Hanga-Roa.dx6053647)

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