Title: La Serena Vacation Rentals from $63: Search Short-Term Rentals | Expedia.com

[La Serena Travel Guide](https://expedia.com/La-Serena.dx2139)[Hotels in La Serena](https://expedia.com/La-Serena-Hotels.d2139.Travel-Guide-Hotels)[Flights to La Serena](https://expedia.com/Cheap-Flights-To-La-Serena.d2139.Travel-Guide-Flights)[Things to do in La Serena](https://expedia.com/Things-To-Do-In-La-Serena.d2139.Travel-Guide-Activities)[Car Rentals in La Serena](https://expedia.com/Car-Rentals-In-La-Serena.d2139.Car-Rental-Guide)[La Serena Vacation Packages](https://expedia.com/La-Serena.d2139.Destination-Travel-Guides)

![Lighthouse at La Serena, Chile](https://images.trvl-media.com/place/2139/d4916bcd-6a4a-4c25-b665-93e13c32c0c5.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/2139/d4916bcd-6a4a-4c25-b665-93e13c32c0c5.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=2139&startDate=2026-02-27&endDate=2026-03-01&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=2139&startDate=2026-04-10&endDate=2026-04-12&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 8 - May 10](https://www.expedia.com/Hotel-Search?regionId=2139&startDate=2026-05-08&endDate=2026-05-10&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jun 5 - Jun 7](https://www.expedia.com/Hotel-Search?regionId=2139&startDate=2026-06-05&endDate=2026-06-07&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for La Serena vacation rentals

![Garden](https://images.trvl-media.com/lodging/9000000/8060000/8057300/8057286/19dd421c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/9000000/8060000/8057300/8057286/093fb92b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/9000000/8060000/8057300/8057286/ff30d372.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Superior Apartment | View from room](https://images.trvl-media.com/lodging/9000000/8060000/8057300/8057286/b486105f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apart Hotel y Cabañas Vegasur

[](https://www.expedia.com/La-Serena-Hotels-Apart-Hotel-Y-Cabanas-Vegasur.h8057286.Hotel-Information)

La Serena

8.6/10

Excellent

(93 reviews)

"LIMPIEZA BUENA, NO TENGO REPAROS AL RESPECTO."

![Chile](https://a.travel-assets.com/egds/marks/flags/cl.svg)

Martin

$63 nightly

$63 total

Mar 12 - Mar 13

[](https://www.expedia.com/La-Serena-Hotels-Apart-Hotel-Y-Cabanas-Vegasur.h8057286.Hotel-Information)

![32-inch flat-screen TV with cable channels, first-run movies](https://images.trvl-media.com/lodging/88000000/87730000/87728000/87727948/3cd1e7d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/88000000/87730000/87728000/87727948/682833ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/88000000/87730000/87728000/87727948/ca60aef8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Classic Double or Twin Room | Living area | 32-inch flat-screen TV with cable channels, first-run movies](https://images.trvl-media.com/lodging/88000000/87730000/87728000/87727948/26ad5929.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Domos Dream hotel cabañas

[](https://www.expedia.com/La-Serena-Hotels-Domos-Dream-Hotel-Cabanas.h87727948.Hotel-Information)

La Serena

8.6/10

Excellent

(4 reviews)

"It was far away."

![Mexico](https://a.travel-assets.com/egds/marks/flags/mx.svg)

Sergio

$81 nightly

$81 total

Mar 1 - Mar 2

[](https://www.expedia.com/La-Serena-Hotels-Domos-Dream-Hotel-Cabanas.h87727948.Hotel-Information)

![Apartment, Patio, Garden View | Terrace/patio](https://images.trvl-media.com/lodging/118000000/117980000/117973300/117973282/bab6bbc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, Patio, Garden View | Free WiFi](https://images.trvl-media.com/lodging/118000000/117980000/117973300/117973282/884ef195.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, Patio, Garden View | Free WiFi](https://images.trvl-media.com/lodging/118000000/117980000/117973300/117973282/c831edfd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, Patio, Garden View | Living area](https://images.trvl-media.com/lodging/118000000/117980000/117973300/117973282/ab402c0d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Yunkai Home

[](https://www.expedia.com/Vicuna-Hotels-Yunkai-Home.h117973282.Hotel-Information)

Vicuña

$104 nightly

$104 total

Mar 1 - Mar 2

[](https://www.expedia.com/Vicuna-Hotels-Yunkai-Home.h117973282.Hotel-Information)

![3 outdoor pools, open 11:00 AM to 8:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/105000000/104290000/104287600/104287525/578aa723.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/105000000/104290000/104287600/104287525/f5bcd040.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/105000000/104290000/104287600/104287525/dac6a47a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/105000000/104290000/104287600/104287525/22cbea61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabaña Villa Los Plátanos

[](https://www.expedia.com/La-Serena-Hotels-Cabana-Villa-Los-Platanos.h104287525.Hotel-Information)

La Serena

10/10

Exceptional

(2 reviews)

$73 nightly

$73 total

Mar 16 - Mar 17

[](https://www.expedia.com/La-Serena-Hotels-Cabana-Villa-Los-Platanos.h104287525.Hotel-Information)

![15 outdoor pools, open 10:00 AM to 8:30 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/105000000/104080000/104078900/104078804/f4b7b838.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/105000000/104080000/104078900/104078804/6cab6f66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, free WiFi](https://images.trvl-media.com/lodging/105000000/104080000/104078900/104078804/268a5376.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![BBQ/picnic area](https://images.trvl-media.com/lodging/105000000/104080000/104078900/104078804/e32f8475.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabañas de la Costa

[](https://www.expedia.com/La-Serena-Hotels-Cabanas-De-La-Costa.h104078804.Hotel-Information)

La Serena

10/10

Exceptional

(2 reviews)

"They were very hospitable. And I would recommend it to anybody that comes to coquimbo."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Erwin

$147 nightly

$147 total

Feb 17 - Feb 18

[](https://www.expedia.com/La-Serena-Hotels-Cabanas-De-La-Costa.h104078804.Hotel-Information)

![Business center](https://images.trvl-media.com/lodging/21000000/20070000/20066100/20066075/e8460db3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Honeymoon Apartment, 1 Queen Bed, Accessible, Beachfront | Living room | 49-inch flat-screen TV with cable channels, Smart TV](https://images.trvl-media.com/lodging/21000000/20070000/20066100/20066075/82544b38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, 2 Bedrooms, Ocean View, Beachside | Frette Italian sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/21000000/20070000/20066100/20066075/f6d698b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Honeymoon Apartment, 1 Queen Bed, Accessible, Beachfront | Terrace/patio](https://images.trvl-media.com/lodging/21000000/20070000/20066100/20066075/83e753f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### La Choza VIP Turquesa en La Serena

[](https://www.expedia.com/La-Serena-Hotels-La-Choza-VIP-Turquesa-En-La-Serena.h20066075.Hotel-Information)

Coquimbo

7.6/10

Good

(11 reviews)

"The apartment was very good for my needs and close to the conference centre. Safe, clean, well appointed. Yanitza was a big help and responsive to WhatsApp messages."

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

Andrew

[](https://www.expedia.com/La-Serena-Hotels-La-Choza-VIP-Turquesa-En-La-Serena.h20066075.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/96000000/95420000/95417200/95417107/0c3119a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin | Private kitchen | Full-size fridge, microwave, oven, toaster](https://images.trvl-media.com/lodging/96000000/95420000/95417200/95417107/c9453223.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cabin | 2 bedrooms, free WiFi, bed sheets](https://images.trvl-media.com/lodging/96000000/95420000/95417200/95417107/520274e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/96000000/95420000/95417200/95417107/d8bfe457.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Parcela Los Nonos

[](https://www.expedia.com/Vicuna-Hotels-Parcela-Los-Nonos.h95417107.Hotel-Information)

Vicuña

[](https://www.expedia.com/Vicuna-Hotels-Parcela-Los-Nonos.h95417107.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/112000000/111450000/111440900/111440895/6a3317ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Room | 2 bedrooms, individually decorated, individually furnished, desk](https://images.trvl-media.com/lodging/112000000/111450000/111440900/111440895/acf8d706.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/112000000/111450000/111440900/111440895/5b10fbff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Garden](https://images.trvl-media.com/lodging/112000000/111450000/111440900/111440895/19578f2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cabañas Yunkai

[](https://www.expedia.com/Vicuna-Hotels-Cabanas-Yunkai.h111440895.Hotel-Information)

Vicuña

$93 nightly

$93 total

Mar 1 - Mar 2

[](https://www.expedia.com/Vicuna-Hotels-Cabanas-Yunkai.h111440895.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/104000000/103130000/103124200/103124138/7815e33b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property grounds](https://images.trvl-media.com/lodging/104000000/103130000/103124200/103124138/84f4d0ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Smart TV](https://images.trvl-media.com/lodging/104000000/103130000/103124200/103124138/ac9139f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Dining](https://images.trvl-media.com/lodging/104000000/103130000/103124200/103124138/c92589ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Elqui Valley Avocado Farm, 2-bedroom cabin in fabulous Vicuña with WiFi

[](https://www.expedia.com/Vicuna-Hotels-Elqui-Valley-Avocado-Farm.h103124138.Hotel-Information)

Vicuña

$150 nightly

$150 total

Feb 20 - Feb 21

[](https://www.expedia.com/Vicuna-Hotels-Elqui-Valley-Avocado-Farm.h103124138.Hotel-Information)

![In-room safe, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/108000000/107020000/107013800/107013715/84c860a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/108000000/107020000/107013800/107013715/8d5a7f19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Departamento 06 | Private kitchen | Fridge, oven, electric kettle, toaster](https://images.trvl-media.com/lodging/108000000/107020000/107013800/107013715/3a66e21a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Departamento 04 | Living area | 32-inch TV with cable channels](https://images.trvl-media.com/lodging/108000000/107020000/107013800/107013715/ca42be32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### ELDEPTO LA SERENA

[](https://www.expedia.com/Coquimbo-Hotels-ELDEPTO-LA-SERENA.h107013715.Hotel-Information)

Coquimbo

8.0/10

Very Good

(2 reviews)

"Boa localização de fácil acesso, tranquilidade e bom atendimento"

![Brazil](https://a.travel-assets.com/egds/marks/flags/br.svg)

Ricardo Horacio

$50 nightly

$50 total

Mar 2 - Mar 3

[](https://www.expedia.com/Coquimbo-Hotels-ELDEPTO-LA-SERENA.h107013715.Hotel-Information)

![Classic Apartment, Ocean View | Living area](https://images.trvl-media.com/lodging/113000000/112740000/112736400/112736365/86f1a18a_edited_fe19.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Classic Apartment, Ocean View | Bathroom | Towels](https://images.trvl-media.com/lodging/113000000/112740000/112736400/112736365/00dbd73c_edited_789b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Classic Apartment, Ocean View | Living area](https://images.trvl-media.com/lodging/113000000/112740000/112736400/112736365/61eb3aa7_edited_a4a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Classic Apartment, Ocean View | 3 bedrooms, free WiFi](https://images.trvl-media.com/lodging/113000000/112740000/112736400/112736365/3162eba0_edited_5727.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Depto Serena Golf

[](https://www.expedia.com/La-Serena-Hotels-Depto-Serena-Golf.h112736365.Hotel-Information)

La Serena

$277 nightly

$277 total

Feb 19 - Feb 20

[](https://www.expedia.com/La-Serena-Hotels-Depto-Serena-Golf.h112736365.Hotel-Information)

![Outdoor pool](https://images.trvl-media.com/lodging/78000000/77070000/77064300/77064270/630b114c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, oven, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/78000000/77070000/77064300/77064270/cf6506a2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/78000000/77070000/77064300/77064270/7626f621.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Onsite parking](https://images.trvl-media.com/lodging/78000000/77070000/77064300/77064270/5655ceb3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Enjoy Coquimbo Apartment one block away

[](https://www.expedia.com/La-Serena-Hotels-House.h77064270.Hotel-Information)

coquimbo

$164 nightly

$189 total

Feb 19 - Feb 20

[](https://www.expedia.com/La-Serena-Hotels-House.h77064270.Hotel-Information)

![Beach massages](https://images.trvl-media.com/lodging/26000000/25840000/25836900/25836876/d9d1bf94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Apartment, 3 Bedrooms, Non Smoking | Terrace/patio](https://images.trvl-media.com/lodging/26000000/25840000/25836900/25836876/5fe11d75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Apartment, 3 Bedrooms, Non Smoking, City View | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/26000000/25840000/25836900/25836876/b39f32f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family Apartment, 3 Bedrooms, Non Smoking | Living area | Flat-screen TV](https://images.trvl-media.com/lodging/26000000/25840000/25836900/25836876/373f876a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cosmopolita

[](https://www.expedia.com/La-Serena-Hotels-Cosmopolita.h25836876.Hotel-Information)

La Serena

10/10

Exceptional

(2 reviews)

"Highly recommend! The apartment was great and comfortable with everything you need and in a great location, and the owner Yanitza is incredibly nice and helpful and can tell you many things to do and see and is a very friendly person who makes you feel welcome."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

brett

[](https://www.expedia.com/La-Serena-Hotels-Cosmopolita.h25836876.Hotel-Information)

![Dining](https://images.trvl-media.com/lodging/50000000/49240000/49238500/49238439/7c4c2aca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/50000000/49240000/49238500/49238439/353dd86a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bathroom](https://images.trvl-media.com/lodging/50000000/49240000/49238500/49238439/e9bb914a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![](https://images.trvl-media.com/lodging/50000000/49240000/49238500/49238439/32bfcf38.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Cómoda Casa Ubicada en un lindo sector y muy tranquilo, ceca de supermercados.

[](https://www.expedia.com/Coquimbo-Hotels-Comoda-Casa-Ubicada-En-Un-Lindo-Sector-Y-Muy-Tranquilo.h49238439.Hotel-Information)

Coquimbo

$172 nightly

$172 total

Feb 15 - Feb 16

[](https://www.expedia.com/Coquimbo-Hotels-Comoda-Casa-Ubicada-En-Un-Lindo-Sector-Y-Muy-Tranquilo.h49238439.Hotel-Information)

![Beach](https://images.trvl-media.com/lodging/110000000/109730000/109724900/109724820/589b6636.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/110000000/109730000/109724900/109724820/8dc415bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![9 bedrooms, WiFi, bed sheets](https://images.trvl-media.com/lodging/110000000/109730000/109724900/109724820/6b6735c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Beach](https://images.trvl-media.com/lodging/110000000/109730000/109724900/109724820/832f317c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Apartment in Coquimbo

[](https://www.expedia.com/Coquimbo-Hotels-Vrbo-Property.h109724820.Hotel-Information)

Coquimbo

$90 nightly

$90 total

Feb 15 - Feb 16

[](https://www.expedia.com/Coquimbo-Hotels-Vrbo-Property.h109724820.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/39000000/38690000/38686200/38686156/b612c0d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/39000000/38690000/38686200/38686156/6da8abbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/39000000/38690000/38686200/38686156/b7e13fbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/39000000/38690000/38686200/38686156/82d0fa5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Depto un dormitorio amoblado

[](https://www.expedia.com/La-Serena-Hotels-Depto-Un-Dormitorio-Amoblado.h38686156.Hotel-Information)

La Serena

$261 nightly

$261 total

Feb 15 - Feb 16

[](https://www.expedia.com/La-Serena-Hotels-Depto-Un-Dormitorio-Amoblado.h38686156.Hotel-Information)

![Outdoor dining](https://images.trvl-media.com/lodging/106000000/105770000/105769300/105769295/9327bcce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/106000000/105770000/105769300/105769295/2d21f2f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fitness facility](https://images.trvl-media.com/lodging/106000000/105770000/105769300/105769295/e3930909.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/106000000/105770000/105769300/105769295/6338524d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Beautiful & unique beach apartament in the oldest bay and coastal city of Chile 

[](https://www.expedia.com/La-Serena-Hotels-Beautiful-Unique-Beach-Apartament-In-The-Oldest-Bay-And-Coastal-City-Of-Chile.h105769295.Hotel-Information)

La Serena

$110 nightly

$110 total

Feb 16 - Feb 17

[](https://www.expedia.com/La-Serena-Hotels-Beautiful-Unique-Beach-Apartament-In-The-Oldest-Bay-And-Coastal-City-Of-Chile.h105769295.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/111000000/110690000/110681600/110681544/cdc32aa2_edited_f33a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/111000000/110690000/110681600/110681544/7433a20b_edited_9e06.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/111000000/110690000/110681600/110681544/6bc66248.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pool](https://images.trvl-media.com/lodging/111000000/110690000/110681600/110681544/24c0e22b_edited_8db2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Disegni 02 - Apartment in Serena - Sector Casino Enjoy

[](https://www.expedia.com/Coquimbo-Hotels-Dpt-Av-Del-Mar-La-Serena.h110681544.Hotel-Information)

Coquimbo

$194 nightly

$222 total

Feb 17 - Feb 18

[](https://www.expedia.com/Coquimbo-Hotels-Dpt-Av-Del-Mar-La-Serena.h110681544.Hotel-Information)

![4 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/100000000/99430000/99427300/99427287/d54d61b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/100000000/99430000/99427300/99427287/d474b0fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/100000000/99430000/99427300/99427287/99a0d71d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Living area](https://images.trvl-media.com/lodging/100000000/99430000/99427300/99427287/b782b62b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Serene and Luxury Refuge in the Elqui Valley: Valle Hermoso House

[](https://www.expedia.com/La-Serena-Hotels-Vrbo-Property.h99427287.Hotel-Information)

Coquimbo

$375 nightly

$375 total

Feb 16 - Feb 17

[](https://www.expedia.com/La-Serena-Hotels-Vrbo-Property.h99427287.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-02-28&endDate=2026-03-01&regionId=2139&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

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## Find vacation rentals that suit your style

Apartments

[](https://www.expedia.com/Hotel-Search?destination=La+Serena%2C+Coquimbo+Region%2C+Chile&regionId=2139&latLong=-29.90267%2C-71.251938&adults=2&startDate=2026-05-15&d1=2026-05-15&endDate=2026-05-18&d2=2026-05-18&lodging=APARTMENT)

Aparthotels

[](https://www.expedia.com/Hotel-Search?destination=La+Serena%2C+Coquimbo+Region%2C+Chile&regionId=2139&latLong=-29.90267%2C-71.251938&adults=2&startDate=2026-05-15&d1=2026-05-15&endDate=2026-05-18&d2=2026-05-18&lodging=APART_HOTEL)

Private vacation homes

[](https://www.expedia.com/Hotel-Search?destination=La+Serena%2C+Coquimbo+Region%2C+Chile&regionId=2139&latLong=-29.90267%2C-71.251938&adults=2&startDate=2026-05-15&d1=2026-05-15&endDate=2026-05-18&d2=2026-05-18&lodging=VACATION_HOME)

Condos

[](https://www.expedia.com/Hotel-Search?destination=La+Serena%2C+Coquimbo+Region%2C+Chile&regionId=2139&latLong=-29.90267%2C-71.251938&adults=2&startDate=2026-05-15&d1=2026-05-15&endDate=2026-05-18&d2=2026-05-18&lodging=CONDO)

Villas

[](https://www.expedia.com/Hotel-Search?destination=La+Serena%2C+Coquimbo+Region%2C+Chile&regionId=2139&latLong=-29.90267%2C-71.251938&adults=2&startDate=2026-05-15&d1=2026-05-15&endDate=2026-05-18&d2=2026-05-18&lodging=VILLA)

Cottages

[](https://www.expedia.com/Hotel-Search?destination=La+Serena%2C+Coquimbo+Region%2C+Chile&regionId=2139&latLong=-29.90267%2C-71.251938&adults=2&startDate=2026-05-15&d1=2026-05-15&endDate=2026-05-18&d2=2026-05-18&lodging=COTTAGE)

Cabins

[](https://www.expedia.com/Hotel-Search?destination=La+Serena%2C+Coquimbo+Region%2C+Chile&regionId=2139&latLong=-29.90267%2C-71.251938&adults=2&startDate=2026-05-15&d1=2026-05-15&endDate=2026-05-18&d2=2026-05-18&lodging=CABIN)

Chalets

[](https://www.expedia.com/Hotel-Search?destination=La+Serena%2C+Coquimbo+Region%2C+Chile&regionId=2139&latLong=-29.90267%2C-71.251938&adults=2&startDate=2026-05-15&d1=2026-05-15&endDate=2026-05-18&d2=2026-05-18&lodging=CHALET)

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## Top La Serena Hotel Reviews

![Hotel Diego de Almagro La Serena](https://images.trvl-media.com/lodging/16000000/15580000/15570400/15570373/332a6c16_y.jpg)

### Hotel Diego de Almagro La Serena

10/10 Excellent

"Efficient front-desk staff, a comfortable quiet room on the 3rd floor,and an excellent breakfast "

[](https://expedia.com/La-Serena-Hotels-Hotel-Diego-De-Almagro-La-Serena.h15570373.Hotel-Information)

![Hotel Club La Serena](https://images.trvl-media.com/lodging/1000000/430000/428300/428299/074325cc_y.jpg)

### Hotel Club La Serena

10/10 Excellent

"Friendly helpful staff, right across the street from the beach, an easy walk to some restaurants and sights and a nice comfy room, thumbs up!"

[](https://expedia.com/La-Serena-Hotels-Hotel-Club-La-Serena.h428299.Hotel-Information)

![Primera Hacienda Hotel Boutique](https://images.trvl-media.com/lodging/14000000/13360000/13357200/13357169/7723f12d_y.jpg)

### Primera Hacienda Hotel Boutique

10/10 Excellent

"We had a very warm welcome from the moment we arrived until the moment we checked out. Maria helped in every way she could from booking tours to lending us a beach towel and parasol. She even got up to provide breakfast at 5.45am as we were leaving on a tour at 6.05am. The normal breakfast started at 7am The room was beautiful and the bed extremely comfortable. The hotel has a gorgeous garden, perfect for relaxing in."

[](https://expedia.com/La-Serena-Hotels-Primera-Hacienda-Hotel-Boutique.h13357169.Hotel-Information)

![Hotel y Cabañas Campanario](https://images.trvl-media.com/lodging/3000000/2140000/2133800/2133775/e8ace86b_y.jpg)

### Hotel y Cabañas Campanario

10/10 Excellent

"Location, location, location. That is all you need to know. Oh, they have secure motorcycle parking. That too is important. And the breakfast is AMAZING! But Location Rules. And this is just an amazing location. If you want a new, Americanized place, this might not be it. Hot shower too!"

[](https://expedia.com/La-Serena-Hotels-Hotel-Campanario-Del-Mar.h2133775.Hotel-Information)

![Hotel Canto del Mar](https://images.trvl-media.com/lodging/113000000/112970000/112966800/112966711/1ec5bba6_y.jpg)

### Hotel Canto del Mar

6/10 Okay

"The room looked different than the pictures. There was a dirty carpet and a bad smell."

[](https://expedia.com/La-Serena-Hotels-Hotel-Canto-Del-Mar.h112966711.Hotel-Information)

![Hotel Francisco de Aguirre Serena](https://images.trvl-media.com/lodging/2000000/1110000/1100500/1100409/68a59b71_y.jpg)

### Hotel Francisco de Aguirre Serena

10/10 Excellent

"Staff were brilliant, loved the hotel generally- difficult to get hot water for a shower but the hotel was so lovely I wouldn’t hesitate to return"

[](https://expedia.com/La-Serena-Hotels-Hotel-Francisco-De-Aguirre-Serena.h1100409.Hotel-Information)

![Hotel Diego de Almagro La Serena Express](https://images.trvl-media.com/lodging/111000000/110440000/110439900/110439848/69704642_y.jpg)

### Hotel Diego de Almagro La Serena Express

10/10 Excellent

"Great property with lots of amenities. Only thing that l missed was an iron for my shirts. Other than that l give it a 10"

[](https://expedia.com/La-Serena-Hotels-Hotel-Diego-De-Almagro-La-Serena-Express.h110439848.Hotel-Information)

![Hotel Chagual](https://images.trvl-media.com/lodging/25000000/24220000/24214200/24214154/0947b4e2_y.jpg)

### Hotel Chagual

10/10 Excellent

"Todo perfecto"

[](https://expedia.com/La-Serena-Hotels-Hotel-Chagual.h24214154.Hotel-Information)

![Cabañas MarSerena](https://images.trvl-media.com/lodging/16000000/15370000/15362400/15362350/cb56fcec_y.jpg)

### Cabañas MarSerena

10/10 Excellent

"very nice place to stay close to the beach, reasonably price and everybody there was very very pleasant"

[](https://expedia.com/La-Serena-Hotels-Cabanas-MarSerena.h15362350.Hotel-Information)

## Find out more about La Serena

**Everything you need to know about La Serena vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the La Serena vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect La Serena vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**La Serena vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in La Serena. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit La Serena in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $63 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on La Serena rentals**

At Expedia, we put the best La Serena vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top La Serena rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream La Serena vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around La Serena. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

## Explore a world of travel with Expedia

- Trending destinations on Expedia.com
- All accommodation types in La Serena

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- [Ocean City Vacation Rentals ](https://www.expedia.com/Ocean-City-Vacation-Rentals.d9151.Travel-Guide-VacationRentals)
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- [Clearwater Beach Vacation Rentals ](https://www.expedia.com/Clearwater-Beach-Vacation-Rentals.d10759.Travel-Guide-VacationRentals)
- [Palm Springs Vacation Rentals ](https://www.expedia.com/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals)
- [Florida Keys Vacation Rentals ](https://www.expedia.com/Florida-Keys-Vacation-Rentals.d6023765.Travel-Guide-VacationRentals)
- [Lake Tahoe Vacation Rentals ](https://www.expedia.com/South-Lake-Tahoe-Vacation-Rentals.d10150.Travel-Guide-VacationRentals)
- [Lake of the Ozarks Vacation Rentals ](https://www.expedia.com/Lake-Ozark-Vacation-Rentals.d177772.Travel-Guide-VacationRentals)
- [Florida Vacation Rentals ](https://www.expedia.com/Destinations-In-Florida.d211.Vacation-Rental-Destinations)
- [Hawaii Vacation Rentals ](https://www.expedia.com/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations)
- [Michigan Vacation Rentals ](https://www.expedia.com/Destinations-In-Michigan.d224.Vacation-Rental-Destinations)

- [Apartments in La Serena ](https://expedia.com/La-Serena-Apartments.d2139-aaApartments.Travel-Guide-Accommodation)
- [Cottages in La Serena ](https://expedia.com/La-Serena-Cottages.d2139-aaCottages.Travel-Guide-Accommodation)
- [Cabin Rentals in La Serena ](https://expedia.com/La-Serena-Cabins.d2139-aaCabins.Travel-Guide-Accommodation)
- [Hostels in La Serena ](https://expedia.com/La-Serena-Hostels.d2139-aaHostels.Travel-Guide-Accommodation)
- [Aparthotels in La Serena ](https://expedia.com/La-Serena-Apart-Hotels.d2139-aaApartHotels.Travel-Guide-Accommodation)
- [B&B in La Serena ](https://expedia.com/La-Serena-Bed-And-Breakfast.d2139-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Villas in La Serena ](https://expedia.com/La-Serena-Villas.d2139-aaVillas.Travel-Guide-Accommodation)

## Frequently asked questions

### Can I find a vacation rental in La Serena?

### What are some of the best vacation rentals in La Serena?

### How many vacation rentals will I find in La Serena?

### What can I see and do in La Serena?

### What are vacation rentals like in La Serena?

### Expedia's Latest Trends

Hotels

- [Hotel Rooms in Paiguano](https://expedia.com/Paiguano-Hotels.d6344315.Travel-Guide-Hotels)
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- [Hotel Rooms in La Higuera](https://expedia.com/La-Higuera-Hotels.d6203805.Travel-Guide-Hotels)
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- [Hotel Rooms in Vina del Mar](https://expedia.com/Vina-Del-Mar-Hotels.d6053651.Travel-Guide-Hotels)
- [Hotel Rooms in Andacollo](https://expedia.com/Andacollo-Hotels.d6203778.Travel-Guide-Hotels)

Flights

- [Flights to PUQ](https://expedia.com/Cheap-Flights-To-Torres-Del-Paine.d6127101.Travel-Guide-Flights)
- [Flights to PUQ](https://expedia.com/Cheap-Flights-To-Punta-Arenas.d2904.Travel-Guide-Flights)
- [Flights to CJC](https://expedia.com/Cheap-Flights-To-San-Pedro-De-Atacama.d500224.Travel-Guide-Flights)
- [Flights to ANF](https://expedia.com/Cheap-Flights-To-Antofagasta.d382.Travel-Guide-Flights)
- [Flights to CCP](https://expedia.com/Cheap-Flights-To-Los-Angeles.d500226.Travel-Guide-Flights)
- [Flights to VAP](https://expedia.com/Cheap-Flights-To-Cartagena.d6236111.Travel-Guide-Flights)

Cars

- [Car rentals in San Pedro de Atacama](https://expedia.com/Car-Rentals-In-San-Pedro-De-Atacama.d500224.Car-Rental-Guide)
- [Car rentals in Los Angeles](https://expedia.com/Car-Rentals-In-Los-Angeles.d500226.Car-Rental-Guide)
- [Car rentals in Punta Arenas](https://expedia.com/Car-Rentals-In-Punta-Arenas.d2904.Car-Rental-Guide)
- [Get Your Car Car Rentals In Vicuna](https://expedia.com/Get-Your-Car-Car-Rentals-In-Vicuna.d6203808-c1120.Car-Rental-Guide-Suppliers)
- [Car rental La Serena Airport (LSC)](https://expedia.com/Car-Rentals-In-La-Florida.d6029785.Car-Rental-Guide)

Activities

- [Things to do in San Antonio](https://expedia.com/Things-To-Do-In-San-Antonio.d6336623.Travel-Guide-Activities)
- [Things to do in Valparaiso](https://expedia.com/Things-To-Do-In-Valparaiso.d602827.Travel-Guide-Activities)
- [Things to do in Coquimbo](https://expedia.com/Things-To-Do-In-Coquimbo.d6024027.Travel-Guide-Activities)
- [Things to do in Vina del Mar](https://expedia.com/Things-To-Do-In-Vina-Del-Mar.d6053651.Travel-Guide-Activities)
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Packages

- [Museo Arqueológico](https://expedia.com/Museo-Arqueologico-La-Serena.d553248621532374497.Vacation-Attraction)
- [Mall Plaza La Serena](https://expedia.com/Mall-Plaza-La-Serena-La-Serena.d6311978.Vacation-Attraction)
- [Observatorio Turístico Collowara](https://expedia.com/Observatorio-Turistico-Collowara-La-Serena.d553248621532374491.Vacation-Attraction)

General

- [Visit Concepción](https://expedia.com/Concepcion.dx790)
- [Visit Valparaiso](https://expedia.com/Valparaiso.dx602827)
- [Visit Vina del Mar](https://expedia.com/Vina-Del-Mar.dx6053651)
- [Visit Los Andes](https://expedia.com/Los-Andes.dx6272982)
- [Visit Hanga Roa](https://expedia.com/Hanga-Roa.dx6053647)

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