Find spa resorts & hotels in Mission Valley, San Diego from $112

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Top Mission Valley Resorts & Hotels with Spas

Handlery Hotel

3.5 star property
Mission Valley
8.2 out of 10, Very Good, (2218)
"Staff was amazing and very accommodating. Always recommended staying here. "
United States
Taja
$97 nightly
The price is $112
Dec 1 - Dec 2
Total with taxes and fees
Handlery Hotel

Legacy Resort Hotel & Spa

4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (2964)
"Great stay"
United States
Songkwon
$125 nightly
The price is $144
Nov 30 - Dec 1
Total with taxes and fees
Legacy Resort Hotel & Spa

Hilton San Diego Bayfront

4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1825)
"Great location , beautiful restaurant and nice grounds"
United States
Dawn
$125 nightly
The price is $146
Dec 22 - Dec 23
Total with taxes and fees
Hilton San Diego Bayfront

The Westin San Diego Bayview

4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1036)
"Spacious rooms , great staff "
United States
Jessica
$143 nightly
The price is $166
Dec 19 - Dec 20
Total with taxes and fees
The Westin San Diego Bayview

Hyatt Regency Mission Bay Spa and Marina

4.0 star property
Mission Bay
8.4 out of 10, Very Good, (1571)
"Loved our stay "
United States
Jeremy
$198 nightly
The price is $228
Nov 30 - Dec 1
Total with taxes and fees
Hyatt Regency Mission Bay Spa and Marina

Sycuan Casino Resort

4.0 star property
El Cajon
9.2 out of 10, Wonderful, (1630)
"Nice hotel and friendly staff. Will definitely stay again ."
United States
Lorna
$118 nightly
The price is $129
Dec 1 - Dec 2
Total with taxes and fees
Sycuan Casino Resort

Omni San Diego Hotel at the Ballpark

4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (2065)
"It was an amazing stay "
United States
Alejandra
$217 nightly
The price is $251
Dec 16 - Dec 17
Total with taxes and fees
Omni San Diego Hotel at the Ballpark

San Diego Mission Bay Resort

4.0 star property
Mission Bay
8.4 out of 10, Very Good, (1309)
"great stay! Food was great and my kids loved the pool and location"
United States
ANDREA
$207 nightly
The price is $237
Nov 30 - Dec 1
Total with taxes and fees
San Diego Mission Bay Resort

Best Western Plus Island Palms Hotel & Marina

3.0 star property
Point Loma
8.8 out of 10, Excellent, (1558)
"Nice hotel "
United States
Anthony
$131 nightly
The price is $151
Dec 15 - Dec 16
Total with taxes and fees
Best Western Plus Island Palms Hotel & Marina

Loews Coronado Bay Resort

4.0 star property
Silver Strand
8.8 out of 10, Excellent, (1067)
"My stay was wonderful! "
United States
Jeanine
$222 nightly
The price is $247
Dec 14 - Dec 15
Total with taxes and fees
Loews Coronado Bay Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Mission Valley

Top Mission Valley attractions for a relaxing vacation

Mission Valley offers a variety of points of interest that perfectly complement your spa getaway. Start your day with a tranquil walk along the San Diego River Trail, where you can immerse yourself in nature and enjoy picturesque views. For a unique experience, visit the nearby Mission San Diego de Alcalá, the first of California's 21 missions, where you can explore beautiful gardens and historic architecture. Families can enjoy a fun-filled day at SeaWorld San Diego, where thrilling rides and marine life encounters await, making it a great spot for kids and adults alike. If shopping is on your agenda, the Fashion Valley Mall is just minutes away, featuring upscale boutiques and dining options to indulge your senses. After a day of exploration, retreat to one of Mission Valley's hotels that boast full-service spas, such as the Westin San Diego Gaslamp Quarter, where you can unwind with rejuvenating treatments, or enjoy a refreshing dip in luxurious pools. Each hotel offers attentive service, ensuring you feel pampered throughout your stay, with convenient access to all the attractions and a serene atmosphere to recharge.

Find the best hotels & resorts with spas in Mission Valley

For travelers seeking relaxation and rejuvenation in Mission Valley, San Diego, these top hotels offer exceptional spa amenities and serene accommodations. Each hotel provides unique spa experiences that promise to enhance your stay.

Legacy Resort Hotel & Spa

  • Why it's great for tailored spa getaway: The Legacy Resort Hotel & Spa is a haven for spa enthusiasts, an impressive review rating of 9.0. With a full-service spa on-site, guests can indulge in a variety of treatments including Swedish and deep tissue massages, body scrubs, and rejuvenating facials. Couples can enjoy specialized treatment rooms for a romantic experience together, ensuring a perfect retreat for relaxation.
  • Other amenities: Guests can take advantage of the outdoor pool and hot tub, providing a refreshing escape after a spa day. For added convenience, the hotel features a fitness center, terrace, and poolside bar. Complimentary parking and electric car charging stations are available, ensuring ease of access for all travelers. Enjoy daily housekeeping and premium bedding for a restful stay.
  • Neighborhood: Mission Valley
  • Nearby attractions: Hotel Circle - 0.23 miles, University of San Diego - 2.31 miles, Old Town San Diego State Park - 2.16 miles

WorldMark San Diego - Mission Valley

  • Why it's great for tailored spa getaway: WorldMark San Diego - Mission Valley is a well-rated hotel with a review score of 8.2, offering spa accessibility for guests who prioritize relaxation during their stay. This hotel is perfect for travelers looking for a cozy feel with added spa benefits.
  • Other amenities: Guests can take advantage of the outdoor pool and hot tub, along with full kitchen facilities in select rooms. The hotel also features a fitness center and concierge service to help guests navigate local attractions. Self-parking and a game room add to the overall enjoyment for visitors.
  • Neighborhood: Mission Valley
  • Nearby attractions: Hotel Circle - 1.92 miles, University of San Diego - 3.32 miles, Old Town San Diego State Park - 4.04 miles

Handlery Hotel

  • Why it's great for tailored spa getaway: The Handlery Hotel is an inviting retreat for those looking to unwind, featuring an onsite spa that offers a variety of massage treatments. With a solid review rating of 8.0, this hotel provides a comfortable atmosphere for travelers seeking relaxation after a long day of exploring San Diego.
  • Other amenities: Guests can relax in the outdoor pool and hot tub, or enjoy a meal at the poolside bar. The hotel also offers a terrace for outdoor relaxation and self-parking for convenience. A concierge service is available to assist with local activities, and the hotel is located near shopping options, adding to the overall experience.
  • Neighborhood: Mission Valley
  • Nearby attractions: Hotel Circle - 0.05 miles, University of San Diego - 1.97 miles, Old Town San Diego State Park - 2.06 miles

Best Western Inn & Suites San Diego – Zoo/SeaWorld Area

  • Why it's great for tailored spa getaway: This hotel offers spa accessibility and is an affordable choice for those looking to unwind after a day of adventure. With a review rating of 7.6, it provides a comfortable base for travelers seeking both relaxation and fun in San Diego.
  • Other amenities: Guests can enjoy a complimentary breakfast and access to an outdoor pool and hot tub. The hotel also features self-parking and easy access to local attractions like the zoo and SeaWorld. With free toiletries and daily housekeeping, travelers can expect a straightforward stay.
  • Neighborhood: Mission Valley
  • Nearby attractions: Hotel Circle - 1.06 miles, University of San Diego - 1.55 miles, Old Town San Diego State Park - 1.29 miles

Best Western Seven Seas

  • Why it's great for tailored spa getaway: Best Western Seven Seas is a budget-friendly option with spa accessibility, perfect for travelers looking for a relaxing stay without breaking the bank. With a review rating of 7.6, this hotel provides guests with the basics needed for a comfortable retreat in Mission Valley.
  • Other amenities: Guests can enjoy the outdoor pool and hot tub, along with access to nearby hiking and biking trails. The hotel features a fitness center and offers free housekeeping, ensuring a tidy and pleasant stay. Additional amenities include self-parking, an on-site restaurant, and a terrace for outdoor relaxation.
  • Neighborhood: Mission Valley
  • Nearby attractions: Hotel Circle - 0.11 miles, University of San Diego - 2.04 miles, Old Town San Diego State Park - 2.48 miles

Top Mission Valley Hotel Reviews

Frequently asked questions

Looking to vacation at a spa hotel in Mission Valley?
Treat yourself to some pampering and book a hotel with a spa. Travelers love the historical sites and shopping in Mission Valley. Enjoy the museums and beaches during your vacation. Spa hotels are the perfect way to take a break from your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in Mission Valley?
Legacy Resort Hotel & Spa is a top spa hotel featuring a fitness center, a bar, an outdoor pool, and a restaurant. Spend an afternoon at the spa where you'll find facials, body scrubs, and Swedish massages. Another popular spa hotel in Mission Valley is Handlery Hotel.
How many spa hotels are there in Mission Valley?
Among Expedia's 125 accommodation options in Mission Valley, there are 2 spa hotels.
What's there to see and do in Mission Valley?
Enjoy all that Mission Valley has to offer and visit Mission Valley Mall, Fashion Valley Mall, and Snapdragon Stadium. If you have extra time while you're in the area, you might want to stop by San Diego Zoo and Port of San Diego.
What is a Mission Valley spa hotel?
Spa hotels in Mission Valley have on-site spas which offer services like couples massages and a selection of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on vacation.

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