A calm river with clear water, surrounded by dense trees and rocky banks.

O Brien Vacation Rentals

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Check prices for these dates

In two weeks
Oct 2 - Oct 4
In two months
Nov 13 - Nov 15
In three months
Dec 11 - Dec 13
In four months
Jan 8 - Jan 10

Our top choices for O Brien vacation rentals

Terrace/patio

1. Suwannee Music Park about 30 mins away. Royal Springs across the street.

Suwannee Music Park about 30 mins away. Royal Springs across the street.
O'Brien
9.6 out of 10, Exceptional, (7 reviews)
"Ideal for weekend getaways, a quiet place to forget about the stress of the city, the house is so cozy. "
Mexico
Maria Josefina
$268 nightly
The price is $291
Sep 23 - Sep 24
Total with taxes and fees
Suwannee Music Park about 30 mins away. Royal Springs across the street.
House (3 Bedrooms) | Interior

2. Suwannee River Retreat: Pet Friendly, Private Dock

Suwannee River Retreat: Pet Friendly, Private Dock
3.0 star property
Branford
$567 nightly
The price is $606
Sep 22 - Sep 23
Total with taxes and fees
Suwannee River Retreat: Pet Friendly, Private Dock
Pool

3. Suwannee River Retreat: Pet Friendly, Private Dock

Suwannee River Retreat: Pet Friendly, Private Dock
Branford
9.8 out of 10, Exceptional, (8 reviews)
"I had the pleasure of celebrating my birthday at the Bucks River Retreat. We had a group of 8 adults and 2 kids staying there and there was plenty of room for every one. The house is clean and cozy with a fun cabin vibe. The property is absolutely gorgeous! Plenty of room to park, party, cook out, swim and of course enjoy the Suwannee river. The dock is newly redone and fun place to hang out. I can’t wait to go back and stay at the Bucks again. It had every thing you need and so much more."
United States
Hayley
$572 nightly
The price is $607
Sep 22 - Sep 23
Total with taxes and fees
Suwannee River Retreat: Pet Friendly, Private Dock
View from property

4. Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
2.0 star property
High Springs
10.0 out of 10, Exceptional, (269 reviews)
"It was amazing, I loved this trip"
United States
Keren
$209 nightly
The price is $230
Sep 21 - Sep 22
Total with taxes and fees
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
Microwave, oven, stovetop, dishwasher

5. Cozy Lake House, Hot Tub & Close to FL Springs

Cozy Lake House, Hot Tub & Close to FL Springs
Branford
10.0 out of 10, Exceptional, (1 review)
"Juan was so welcoming. The house was clean and had everything we needed for a fun family getaway - and then some! Would love to stay here again. "
United States
Ashley L.
$250 nightly
The price is $266
Sep 21 - Sep 22
Total with taxes and fees
Cozy Lake House, Hot Tub & Close to FL Springs
TV, offices

6. Nook at the Springs | Tiny Home • Full Kitchen

Nook at the Springs | Tiny Home • Full Kitchen
Fort White
9.8 out of 10, Exceptional, (9 reviews)
"Excellent place "
United States
Linay
$154 nightly
The price is $166
Sep 20 - Sep 21
Total with taxes and fees
Nook at the Springs | Tiny Home • Full Kitchen
Outdoor dining

7. Rustic River Cabin 2-bedroom cabin in Branford near Santa Fe River

Rustic River Cabin 2-bedroom cabin in Branford near Santa Fe River
Branford
10.0 out of 10, Exceptional, (12 reviews)
"Hosts are awesome, and there's enough amenities to keep any family busy for as long as they'd like. "
United States
James S.
$236 nightly
The price is $257
Sep 23 - Sep 24
Total with taxes and fees
Rustic River Cabin 2-bedroom cabin in Branford near Santa Fe River
Outdoor dining

8. The Chalet On the Suwannee River

The Chalet On the Suwannee River
Mayo
10.0 out of 10, Exceptional, (1 review)
"We were in the area to check out some local spring and loved the accessibility of this VRBO’s location. This property was amazing and super fun. Can’t wait to go back."
United States
Mandy B.
$254 nightly
The price is $270
Sep 20 - Sep 21
Total with taxes and fees
The Chalet On the Suwannee River
Coffee/tea maker, fridge, microwave, oven

9. The Riverhead | Springs • Pavilion • Grill

The Riverhead | Springs • Pavilion • Grill
Fort White
9.2 out of 10, Wonderful, (15 reviews)
"Very close to springs and other attractions. Property was clean and very inviting on the inside. The beds were comfortable and the decor was very homey. Ample coffee and tea was provided and the kitchen was very equipped for cooking. Overall a really great way to enjoy the nearby springs. "
United States
Nicole
$253 nightly
The price is $271
Sep 20 - Sep 21
Total with taxes and fees
The Riverhead | Springs • Pavilion • Grill
Exterior

10. Beautiful 2 story house overlooking the water. Has arcade & Close to the springs

Beautiful 2 story house overlooking the water. Has arcade & Close to the springs
Live Oak
10.0 out of 10, Exceptional, (81 reviews)
"The home was very peaceful and had fun amenities! The communication with the owner was great."
United States
Leslie D.
$236 nightly
The price is $257
Sep 18 - Sep 19
Total with taxes and fees
Beautiful 2 story house overlooking the water. Has arcade & Close to the springs
Outdoor dining

11. SpringHouse at Convict Springs

SpringHouse at Convict Springs
Mayo
10.0 out of 10, Exceptional, (1 review)
$130 nightly
The price is $138
Sep 21 - Sep 22
Total with taxes and fees
SpringHouse at Convict Springs
House (2 Bedrooms) | Interior

12. < 1 Mi From Suwannee River, Hideaway w/ Lanai

< 1 Mi From Suwannee River, Hideaway w/ Lanai
3.0 star property
Old Town
9.0 out of 10, Wonderful, (2 reviews)
"The Air B & B was amazing. The property and the A B & B was awesone, Clean, Quiet and very comfortable. Although some nights got a bit chilly and this property only had AC no heat. We managed just fine. We left it in perfect conditions according to the directions they wanted it left in. Thank you so much and we will be renting again. We also would recommend this to others. "
United States
Karen
$352 nightly
The price is $387
Sep 18 - Sep 19
Total with taxes and fees
< 1 Mi From Suwannee River, Hideaway w/ Lanai
TV, DVD player

13. O'LE LADYBUG COTTAGE

O'LE LADYBUG COTTAGE
Lake City
9.6 out of 10, Exceptional, (57 reviews)
"Everything was great will stay again if I’m ever in the area"
United States
regina
$180 nightly
The price is $201
Sep 18 - Sep 19
Total with taxes and fees
O'LE LADYBUG COTTAGE
Interior

14. 3 Rivers Crystal Cabin 3/2 Nature Lovers Only -Spring Access

3 Rivers Crystal Cabin 3/2 Nature Lovers Only -Spring Access
Columbia County
10.0 out of 10, Exceptional, (1 review)
"Charming place to stay and enjoy the local rivers!"
United States
Shawn
$231 nightly
The price is $231
Sep 20 - Sep 21
Total with taxes and fees
3 Rivers Crystal Cabin 3/2 Nature Lovers Only -Spring Access
Property grounds

15. "The Loft" on the 11th Tee. No pets! No smoking!

"The Loft" on the 11th Tee. No pets! No smoking!
Lake City
10.0 out of 10, Exceptional, (17 reviews)
"This property is exactly as advertised - cozy, clean and well maintained in a beautiful neighborhood. We very much enjoyed staying there."
United States
Gerald S.
$157 nightly
The price is $174
Sep 21 - Sep 22
Total with taxes and fees
"The Loft" on the 11th Tee. No pets! No smoking!
Property grounds

16. The Best memories are made on the Suwannee River

The Best memories are made on the Suwannee River
Mayo
9.8 out of 10, Exceptional, (58 reviews)
"Was there for a family reunion and was great for what we needed."
United States
Anonymous traveler
$251 nightly
The price is $266
Sep 23 - Sep 24
Total with taxes and fees
The Best memories are made on the Suwannee River
Coffee/tea maker, fridge, microwave, oven

17. Cozy Apartment in Lake City, only minutes from the baseball fields and food!

Cozy Apartment in Lake City, only minutes from the baseball fields and food!
Lake City
10.0 out of 10, Exceptional, (8 reviews)
"Great property!"
United States
Ashley S.
$448 nightly
The price is $497
Sep 21 - Sep 22
Total with taxes and fees
Cozy Apartment in Lake City, only minutes from the baseball fields and food!
Exterior

18. Hillside Abode in the Heart of Historic White Springs and the Suwannee River

Hillside Abode in the Heart of Historic White Springs and the Suwannee River
White Springs
10.0 out of 10, Exceptional, (36 reviews)
"Well worth the cost place was clean organized and a nice little safe haven during our trip "
United States
Cory P.
$248 nightly
The price is $272
Sep 20 - Sep 21
Total with taxes and fees
Hillside Abode in the Heart of Historic White Springs and the Suwannee River
Dining

19. A-frame on the Suwannee River Rendezvous

A-frame on the Suwannee River Rendezvous
Mayo
6.0 out of 10, (1 review)
"Overnight night enroute"
Canada
Doug M.
$265 nightly
The price is $281
Sep 23 - Sep 24
Total with taxes and fees
A-frame on the Suwannee River Rendezvous
Exterior

20. 3-bed 2 bath River house on the Santa fe. 6 miles from Ginnie Springs

3-bed 2 bath River house on the Santa fe. 6 miles from Ginnie Springs
Fort White
10.0 out of 10, Exceptional, (5 reviews)
$254 nightly
The price is $282
Sep 22 - Sep 23
Total with taxes and fees
3-bed 2 bath River house on the Santa fe. 6 miles from Ginnie Springs
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top O Brien Hotel Reviews

Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City

10/10 Excellent
"Great place to stop for the night from the panhandle to South Florida"
Michael 1-night trip
Posted 21 hours ago
Fairfield Inn & Suites Lake City

Find out more about O Brien

Everything you need to know about O Brien vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the O Brien vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect O Brien vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

O Brien vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in O Brien. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit O Brien in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $102 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on O Brien rentals

At Expedia, we put the best O Brien vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top O Brien rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream O Brien vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around O Brien. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find a vacation rental in O Brien?

Yes, we offer vacation rentals close to well known points of interest in O Brien, or you can go with a more secluded option if you're looking for a relaxing stay.

What's the top vacation rental that O Brien has to offer?

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!: Visitors like this O Brien vacation home rental. It is located on the beach and has a balcony, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. Another good choice for your trip to O Brien is MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY.

How many vacation rentals are there in O Brien?

Expedia has 4 vacation rentals for your stay in O Brien.

What’s there to see and do in O Brien?

Suwannee River and Ichetucknee River are a couple of lovely local spots to get outside and enjoy nature. Ichetucknee Springs State Park and Troy Spring State Park are a couple of places you'll find in the larger area.

What’s a vacation rental in O Brien like?

Vacation rentals are private properties you can stay in for several days or longer in O Brien. Vacation rentals offer amenities like WiFi and washers and dryers so you'll have everything you need. If you're concerned about a sanitized environment, a vacation rental can offer a sense of privacy away from public hotel elevators and bustling concierge desks while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a popular choice for small groups.