A calm river with clear water, surrounded by dense trees and rocky banks.

O Brien Vacation Rentals

Check prices for these dates

In two weeks
Sep 11 - Sep 13
In two months
Oct 23 - Oct 25
In three months
Nov 20 - Nov 22
In four months
Dec 18 - Dec 20

Our top choices for O Brien vacation rentals

A covered porch with wooden railings, a table, and four chairs.

1. Suwannee Music Park about 30 mins away. Royal Springs across the street.

Suwannee Music Park about 30 mins away. Royal Springs across the street.
O'Brien
9.6 out of 10, Exceptional, (7 reviews)
"Ideal for weekend getaways, a quiet place to forget about the stress of the city, the house is so cozy. "
Mexico
Maria Josefina
$271 nightly
The price is $294
Sep 2 - Sep 3
Total with taxes and fees
Suwannee Music Park about 30 mins away. Royal Springs across the street.
A river with clear water, a wooden deck, and people standing by the water.

2. MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY

MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY
O'Brien
9.4 out of 10, Exceptional, (59 reviews)
"A great get away for Labor Day weekend to do a little jet skiing with friends on the river and visiting all the local springs!"
United States
Heather H.
$363 nightly
The price is $395
Aug 27 - Aug 28
Total with taxes and fees
MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY

3. Nook at the Springs | Tiny Home • Full Kitchen

Nook at the Springs | Tiny Home • Full Kitchen
Fort White
9.8 out of 10, Exceptional, (9 reviews)
"Excellent place "
United States
Linay
$163 nightly
The price is $175
Aug 27 - Aug 28
Total with taxes and fees
Nook at the Springs | Tiny Home • Full Kitchen
A covered outdoor seating area with wicker chairs and a table, surrounded by a wooden deck and railing.

4. Rustic River Cabin 2-bedroom cabin in Branford near Santa Fe River

Rustic River Cabin 2-bedroom cabin in Branford near Santa Fe River
Branford
10.0 out of 10, Exceptional, (12 reviews)
"Hosts are awesome, and there's enough amenities to keep any family busy for as long as they'd like. "
United States
James S.
$235 nightly
The price is $256
Sep 14 - Sep 15
Total with taxes and fees
Rustic River Cabin 2-bedroom cabin in Branford near Santa Fe River

5. Cozy Lake House, Hot Tub & Close to FL Springs

Cozy Lake House, Hot Tub & Close to FL Springs
Branford
10.0 out of 10, Exceptional, (1 review)
"Juan was so welcoming. The house was clean and had everything we needed for a fun family getaway - and then some! Would love to stay here again. "
United States
Ashley L.
$234 nightly
The price is $249
Aug 27 - Aug 28
Total with taxes and fees
Cozy Lake House, Hot Tub & Close to FL Springs
A cabin with a cozy interior, a dining area, and a view of the forest.

6. Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
2.0 star property
High Springs
10.0 out of 10, Exceptional, (259 reviews)
"Everything was wonderful, I was really very satisfied with my stay in the cabin, I loved it"
United States
Julienne
$198 nightly
The price is $218
Aug 31 - Sep 1
Total with taxes and fees
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
A garden with a small pond, surrounded by various plants and a wooden structure.

7. Kokomo Farms - Cozy Cottage on the Farm

Kokomo Farms - Cozy Cottage on the Farm
Live Oak
9.8 out of 10, Exceptional, (15 reviews)
"Great place for nature!"
United States
Stephen
$143 nightly
The price is $155
Aug 27 - Aug 28
Total with taxes and fees
Kokomo Farms - Cozy Cottage on the Farm
A wooden deck with two benches and a table, surrounded by a wooden fence and trees.

8. SpringHouse at Convict Springs

SpringHouse at Convict Springs
Mayo
10.0 out of 10, Exceptional, (1 review)
$130 nightly
The price is $138
Aug 27 - Aug 28
Total with taxes and fees
SpringHouse at Convict Springs
A wooden deck leading to a gazebo in a grassy park area with trees in the background.

9. Pequeño Refugio Cerca de Rios

Pequeño Refugio Cerca de Rios
Fort White
9.4 out of 10, Exceptional, (8 reviews)
"This was the cutest, charming, little quaint home away from home we’ve stayed. We felt like it was home away from home. Everything was wonderful! "
United States
Tiffany
$144 nightly
The price is $160
Aug 27 - Aug 28
Total with taxes and fees
Pequeño Refugio Cerca de Rios
A covered outdoor seating area with a round wooden table, white wicker chairs, and a black grill.

10. < 1 Mi From Suwannee River, Hideaway w/ Lanai

< 1 Mi From Suwannee River, Hideaway w/ Lanai
3.0 star property
Old Town
9.0 out of 10, Wonderful, (2 reviews)
"The Air B & B was amazing. The property and the A B & B was awesone, Clean, Quiet and very comfortable. Although some nights got a bit chilly and this property only had AC no heat. We managed just fine. We left it in perfect conditions according to the directions they wanted it left in. Thank you so much and we will be renting again. We also would recommend this to others. "
United States
Karen
$352 nightly
The price is $387
Aug 27 - Aug 28
Total with taxes and fees
< 1 Mi From Suwannee River, Hideaway w/ Lanai
A compact kitchen with wooden cabinets, a microwave, and a sink.

11. Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,

Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,
Mayo
10.0 out of 10, Exceptional, (15 reviews)
"Fantastic property very quiet with very friendly animals."
United States
Hevrard
$84 nightly
The price is $88
Sep 4 - Sep 5
Total with taxes and fees
Friendly's river retreat #1 cozy couples cabin in awesome Mayo with WiFi,
Two wooden cabins with porches, one with a red exterior and the other with a brown exterior, surrounded by trees and grassy ground.

12. Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping

Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping
Mayo
9.4 out of 10, Exceptional, (16 reviews)
"Perfect little cabin in the woods. Stacey was awesome. He gave us several great sight-seeing spots. If you are wanting a 5 star Hilton, keep looking but if you are wanting a quiet, cozy, and clean little cabin in the backwoods, THIS IS THE SPOT!!"
United States
Julie J.
$86 nightly
The price is $90
Aug 27 - Aug 28
Total with taxes and fees
Friendlys River Retreat private Rustic Camping Cabin sleeps 4+with tent camping
A house with a porch and a garden with yellow flowers.

13. 3 RIVERS Crystal Cabin Budget 3 Bed 2 Bath IN THE WOODS ~ Nature Lovers Only

3 RIVERS Crystal Cabin Budget 3 Bed 2 Bath IN THE WOODS ~ Nature Lovers Only
Fort White
$254 nightly
The price is $282
Aug 30 - Aug 31
Total with taxes and fees
3 RIVERS Crystal Cabin Budget 3 Bed 2 Bath IN THE WOODS ~ Nature Lovers Only

14. Suwannee River Retreat: Pet Friendly, Private Dock

Suwannee River Retreat: Pet Friendly, Private Dock
Branford
9.8 out of 10, Exceptional, (7 reviews)
"This house is an absolute dream! You truly can’t beat the river views and the peaceful, natural landscape just across the water—it’s the perfect place to relax and unwind. On top of that, the pool and hot tub were amazing bonuses and made the stay feel even more special!!The cabin is comfortable and works perfectly for multiple families or groups to stay together. It had everything we needed, and the cozy atmosphere really made it feel like a true home away from home.We also loveee that it’s...
United States
Lauren
$574 nightly
The price is $609
Aug 31 - Sep 1
Total with taxes and fees
Suwannee River Retreat: Pet Friendly, Private Dock
A modern kitchen with wooden cabinets, a central island with stools, a stove, and a dining area with chairs.

15. The Riverhead | Springs • Pavilion • Grill

The Riverhead | Springs • Pavilion • Grill
Fort White
9.2 out of 10, Wonderful, (15 reviews)
"Very close to springs and other attractions. Property was clean and very inviting on the inside. The beds were comfortable and the decor was very homey. Ample coffee and tea was provided and the kitchen was very equipped for cooking. Overall a really great way to enjoy the nearby springs. "
United States
Nicole
$334 nightly
The price is $360
Sep 7 - Sep 8
Total with taxes and fees
The Riverhead | Springs • Pavilion • Grill
A living room with a grey sofa, a wooden coffee table with vases, a framed picture on the wall, and a view of a grassy area through a door.

16. Stylish Cabin - Nearby Springs

Stylish Cabin - Nearby Springs
Lake City
10.0 out of 10, Exceptional, (5 reviews)
"Amazing place"
United States
Ernesto Randhel
$173 nightly
The price is $187
Sep 1 - Sep 2
Total with taxes and fees
Stylish Cabin - Nearby Springs
A residential street lined with mature trees and a well-maintained lawn.

17. "The Loft" on the 11th Tee. No pets! No smoking!

"The Loft" on the 11th Tee. No pets! No smoking!
Lake City
10.0 out of 10, Exceptional, (17 reviews)
"Shelley was very accommodating, and it had all the amenities we needed. "
United States
Diane T.
$170 nightly
The price is $189
Aug 27 - Aug 28
Total with taxes and fees
"The Loft" on the 11th Tee. No pets! No smoking!
A kitchen with a black induction cooktop, hanging utensils, and a small shelf with kitchen items.

18. Your Cozy Farmhouse Inspired Retreat. Just 5 minutes to I-75. Pets Welcomed.

Your Cozy Farmhouse Inspired Retreat. Just 5 minutes to I-75. Pets Welcomed.
Lake City
9.0 out of 10, Wonderful, (6 reviews)
"Amenities were surprisingly good, glad to have coffee available "
United States
Cindy M.
$158 nightly
The price is $175
Aug 27 - Aug 28
Total with taxes and fees
Your Cozy Farmhouse Inspired Retreat. Just 5 minutes to I-75. Pets Welcomed.
An above-ground swimming pool with a ladder and an umbrella.

19. Private, 1 Mile to Poe, 4 miles to Blue, 6 Miles to Ginnie. Tent/Camper camping

Private, 1 Mile to Poe, 4 miles to Blue, 6 Miles to Ginnie. Tent/Camper camping
High Springs
10.0 out of 10, Exceptional, (2 reviews)
"Love, love, love this place and will definitely be coming back if they'll have us. Lots of space to play games outside and spend some time with the family without other campers right next to you. You couldn't ask for more friendly hosts, everything was easy from checking in to checking out. They showed us around the property and told us about some of the springs as well. My mom's car broke down and they let us rent it for another night last minute, they have two grills and a above ground pool...
United States
Tina O.
$57 nightly
The price is $61
Aug 27 - Aug 28
Total with taxes and fees
Private, 1 Mile to Poe, 4 miles to Blue, 6 Miles to Ginnie. Tent/Camper camping
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top O Brien Hotel Reviews

Best Western Plus Lake City

Best Western Plus Lake City

10/10 Excellent
"Room and hotel was clean and neat. I was well pleased with everything. Fresh brewed coffee and hot breakfast was a great deal."
AL 1-night trip
Posted 4 hours ago
Best Western Plus Lake City

Find out more about O Brien

Everything you need to know about O Brien vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the O Brien vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect O Brien vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

O Brien vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in O Brien. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit O Brien in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $218 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on O Brien rentals

At Expedia, we put the best O Brien vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top O Brien rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream O Brien vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around O Brien. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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Frequently asked questions

Can I find a vacation rental in O Brien?

Yes, we offer vacation rentals close to well known points of interest in O Brien, or you can go with a more secluded option if you're looking for a relaxing stay.

What's the top vacation rental that O Brien has to offer?

Royal Springs Riverfront Retreat on 3 acres, kayak/canoe, boat ramp, huge decks!: Visitors like this O Brien vacation home rental. It is located on the beach and has a balcony, a garden, and a barbecue grill to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. You and your friends and family can relax into your vacation with amenities like a selection of games. Another good choice for your trip to O Brien is MARGARITAVILLE BY THE SUWANNEE RIVER & ROYAL SPRINGS PET FRIENDLY.

How many vacation rentals are there in O Brien?

Expedia has 4 vacation rentals for your stay in O Brien.

What’s there to see and do in O Brien?

Suwannee River and Ichetucknee River are a couple of lovely local spots to get outside and enjoy nature. Ichetucknee Springs State Park and Troy Spring State Park are a couple of places you'll find in the larger area.

What’s a vacation rental in O Brien like?

Vacation rentals are private properties you can stay in for several days or longer in O Brien. Vacation rentals offer amenities like WiFi and washers and dryers so you'll have everything you need. If you're concerned about a sanitized environment, a vacation rental can offer a sense of privacy away from public hotel elevators and bustling concierge desks while still allowing you the excitement and enjoyment of travel. You'll also have more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is a popular choice for small groups.