A large, historic church with a tall bell tower and multiple domes.

Opelousas Vacation Rentals

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

In two weeks
Oct 16 - Oct 18
In two months
Nov 27 - Nov 29
In three months
Dec 25 - Dec 27
In four months
Jan 22 - Jan 24

Our top choices for Opelousas vacation rentals

A small, single-story house with a porch and a wooden fence.

1. Maison D'Memoire Bed & Breakfast Cottages

Maison D'Memoire Bed & Breakfast Cottages
4.0 star property
Rayne
9.6 out of 10, Exceptional, (97 reviews)
"Delightful bed and breakfast venue. Real Southern charm and Lynn (the owner) was a fantastic host. Far exceeded our expectations and genuinely wished we could have stayed longer."
United Kingdom
Paul
$169 nightly
The price is $192
Oct 14 - Oct 15
Total with taxes and fees
Maison D'Memoire Bed & Breakfast Cottages
A modern living room with a sofa, armchair, coffee table, and a dining area with a table and chairs.

2. Enclave 1 Bedroom Suites

Enclave 1 Bedroom Suites
3.0 star property
Lafayette
9.6 out of 10, Exceptional, (28 reviews)
"We had a great stay here! Nice location and had everything we needed for a long weekend."
United States
Mackenzie
$170 nightly
The price is $185
Oct 12 - Oct 13
Total with taxes and fees
Enclave 1 Bedroom Suites
A modern kitchen with white cabinets, a central island with bar stools, a stainless steel refrigerator, and a brick backsplash.

3. Enclave 2 Bedroom Luxury Homes

Enclave 2 Bedroom Luxury Homes
3.0 star property
Lafayette
9.8 out of 10, Exceptional, (9 reviews)
"One of my favorite places I’ve stayed"
United States
Willie
$223 nightly
The price is $256
Oct 4 - Oct 5
Total with taxes and fees
Enclave 2 Bedroom Luxury Homes
A modern kitchen with white cabinetry, stainless steel appliances, a central island with stools, and a ceiling fan.

4. Budget-friendly Hostel-style Private Room

Budget-friendly Hostel-style Private Room
2.0 star property
Freetown - Port Rico
$53 nightly
The price is $61
Oct 4 - Oct 5
Total with taxes and fees
Budget-friendly Hostel-style Private Room
A modern kitchen with white cabinetry, gold handles, a built-in microwave, and a stove.

5. Decatur Inn

Decatur Inn
4.0 star property
Lafayette
$253 nightly
The price is $276
Oct 4 - Oct 5
Total with taxes and fees
Decatur Inn
A spacious living area with a round dining table, a sofa, and a painting of a lake.

6. Canal Inn

Canal Inn
4.0 star property
Lafayette
$223 nightly
The price is $243
Oct 12 - Oct 13
Total with taxes and fees
Canal Inn
A modern kitchen with white cabinetry, a central island with seating, a microwave, stove, and refrigerator.

7. Poydras Inn

Poydras Inn
4.0 star property
Lafayette
$233 nightly
The price is $254
Oct 4 - Oct 5
Total with taxes and fees
Poydras Inn
A modern kitchen with grey cabinets, a central island with a sink, and a dining area with wicker chairs.

8. Enclave 3 Bedroom Luxury Homes

Enclave 3 Bedroom Luxury Homes
4.0 star property
Lafayette
10.0 out of 10, Exceptional, (3 reviews)
"Great Value! I highly recommend this property over hotels in the area."
United States
Roderick
Enclave 3 Bedroom Luxury Homes
A modern kitchen with white cabinets, stainless steel appliances, and a round wooden table with wicker chairs.

9. Rampart Inn

Rampart Inn
4.0 star property
Lafayette
Rampart Inn
A kitchen with a stove, a sink, and a cabinet with a drawer.

10. Charming 1BR Cottage Near Downtown Lafayette

Charming 1BR Cottage Near Downtown Lafayette
2.0 star property
Lafayette
$104 nightly
The price is $120
Oct 5 - Oct 6
Total with taxes and fees
Charming 1BR Cottage Near Downtown Lafayette
A bedroom with a bed, a bedside table, a lamp, a door, and a window with curtains.

11. Private Bedroom in 4BR Home

Private Bedroom in 4BR Home
2.0 star property
Freetown - Port Rico
$73 nightly
The price is $84
Oct 4 - Oct 5
Total with taxes and fees
Private Bedroom in 4BR Home
A compact kitchen with a dining table, chairs, a refrigerator, and a stove.

12. Cozy Modern Studio - Heart of Lafayette

Cozy Modern Studio - Heart of Lafayette
2.0 star property
Downtown Lafayette
$97 nightly
The price is $111
Nov 2 - Nov 3
Total with taxes and fees
Cozy Modern Studio - Heart of Lafayette
A kitchen with a stove, dishwasher, and a red chair.

13. Spacious 2BR Perfect for Work Crews or Families

Spacious 2BR Perfect for Work Crews or Families
2.0 star property
Freetown - Port Rico
$147 nightly
The price is $169
Nov 2 - Nov 3
Total with taxes and fees
Spacious 2BR Perfect for Work Crews or Families
A hallway with a wooden floor leading to a laundry area with a washing machine and dryer.

14. Cozy 1BR Cottage w Kitchen Laundry

Cozy 1BR Cottage w Kitchen Laundry
2.0 star property
Downtown Lafayette
$68 nightly
The price is $79
Nov 2 - Nov 3
Total with taxes and fees
Cozy 1BR Cottage w Kitchen Laundry
Room

15. Magnolia House in Lafayette

Magnolia House in Lafayette
2.0 star property
McComb-Veazey
10.0 out of 10, Exceptional, (1 review)
$267 nightly
The price is $307
Oct 13 - Oct 14
Total with taxes and fees
Magnolia House in Lafayette
A two-story house with a front porch, a small window, and a door.

16. Downtown Lafayette 4BR Home With Parking

Downtown Lafayette 4BR Home With Parking
2.0 star property
Downtown Lafayette
$139 nightly
The price is $160
Oct 26 - Oct 27
Total with taxes and fees
Downtown Lafayette 4BR Home With Parking
A room with a wooden ceiling, a bed, a sofa, a dining table with chairs, and a small table with a lamp.

17. Cozy 1BR Near Downtown Lafayette

Cozy 1BR Near Downtown Lafayette
2.0 star property
Freetown - Port Rico
$160 nightly
The price is $184
Oct 5 - Oct 6
Total with taxes and fees
Cozy 1BR Near Downtown Lafayette
A bedroom with a bed, a nightstand, a dresser, a ceiling fan, and a window with blinds.

18. Mariners Lodge in Lafayette

Mariners Lodge in Lafayette
2.0 star property
McComb-Veazey
$152 nightly
The price is $175
Oct 4 - Oct 5
Total with taxes and fees
Mariners Lodge in Lafayette
A kitchen with a refrigerator, sink, wooden bench, and a trash can.

19. Charming 3BR Home Near Downtown Lafayette

Charming 3BR Home Near Downtown Lafayette
2.0 star property
Downtown Lafayette
$168 nightly
The price is $193
Oct 29 - Oct 30
Total with taxes and fees
Charming 3BR Home Near Downtown Lafayette
A spacious living room with a wooden floor, two grey sofas, a coffee table, and a TV mounted on a wooden cabinet.

20. Steps From Downtown Minutes to the Airport

Steps From Downtown Minutes to the Airport
2.0 star property
McComb-Veazey
6.0 out of 10, (2 reviews)
"The house is cute but tucked between two rundown homes and in a very sketchy, unsafe part of town. It was not safe for my family and we did not stay."
United States
Meredith
$210 nightly
The price is $242
Oct 5 - Oct 6
Total with taxes and fees
Steps From Downtown Minutes to the Airport
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Opelousas Hotel Reviews

Drury Inn & Suites Lafayette, LA

Drury Inn & Suites Lafayette, LA

10/10 Excellent
"Room was clean and comfortable. Staff was friendly o complaints. Would stay again"
Kimberly 1-night trip
Posted 11 hours ago
Drury Inn & Suites Lafayette, LA

Find out more about Opelousas

Everything you need to know about Opelousas vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Opelousas vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Opelousas vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Opelousas vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Opelousas. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Opelousas in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $119 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Opelousas rentals

At Expedia, we put the best Opelousas vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Opelousas rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Opelousas vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Opelousas. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Can I find vacation rentals in Opelousas?

Yes, we give you a choice of vacation rentals in Opelousas close to Louisiana Orphan Train Museum, or you can select a more remote option if you're looking for extra privacy while you relax. Opelousas is known for its casinos and cafes. Make sure you have time to check out the art and churches during your trip.

What are some of the best vacation rentals that Opelousas has to offer?

Enclave 1 Bedroom Suites: This vacation home rental near Opelousas has air-conditioning and free WiFi to help you feel perfectly comfortable in your new surroundings. Amenities like a coffee maker and free parking are also available for your convenience.

How many vacation rentals are there in Opelousas?

Choose from 5 Expedia vacation rentals in Opelousas for a memorable vacation.

What’s there to see and do in Opelousas?

Cultural attractions include Louisiana Orphan Train Museum and Fireman's Museum, whereas South Park is one spot to enjoy nature. Evangeline Downs Racetrack & Casino and Opelousas Historic District are other places to visit while you're in town.

What are vacation rentals like in Opelousas?

Vacation rentals are privately owned accommodations you can reserve for several days or more in Opelousas. Vacation rentals feature amenities such as kitchens and laundry facilities to help you enjoy your stay. If you're concerned about cleanliness, a vacation rental can provide a sense of safety away from public hotel elevators and busy lobbies while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is a great option for a small group gathering.