
Opelousas Vacations from $564
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Your Opelousas Vacation
There's no better way to embark on an adventure than with one of our vacation packages to Opelousas. The rich history and cultural experiences are a couple of the countless reasons to spend some time in this interesting city. Be sure to spend time sightseeing during your trip to Opelousas. Louisiana Orphan Train Museum and St. Landry Catholic Church are some well-known attractions to check out. Don't delay visiting this destination any longer. Your dream Opelousas vacation is a couple of clicks away with Expedia.
The Latest Opelousas vacation packages
Price found within the past 48 hours. Click for updated prices.

Enclave 1 Bedroom Suites
Price was $673, price is now $564 per person
$564
per person
Jan 28 - Feb 1
found 1 day ago
Roundtrip non-stop flight included
San Diego (SAN) to Lafayette (LFT)
9.6/10 Exceptional! (33 reviews)
Good location not far from good places, host response was great, only issue I had was a few stains on the towels and possible pet hair but other then that it was a overall great place, would stay again
Reviewed on Nov 8, 2026



Enclave 3 Bedroom Luxury Homes
Price was $906, price is now $751 per person
$751
per person
Jan 28 - Feb 1
found 1 day ago
Roundtrip non-stop flight included
San Diego (SAN) to Lafayette (LFT)
10/10 Exceptional! (3 reviews)
Great Value! I highly recommend this property over hotels in the area.
Reviewed on Sep 17, 2026

Stay near popular Opelousas attractions
Opelousas Hotel Deals

Days Inn & Suites by Wyndham Opelousas
5761 I-49 S Service Rd Opelousas LA
Fully refundableReserve now, pay when you stay
$68 nightly
The price is $80 total per night from Nov 22 to Nov 23
$80 total
Nov 22 - Nov 23
Total with taxes and fees
7/10 Good! (784 reviews)
"Cleans room nice staff"
Reviewed on Nov 7, 2026

Hampton Inn Opelousas
1700 Commerce Blvd Opelousas LA
Fully refundableReserve now, pay when you stay
$104 nightly
The price is $122 total per night from Dec 6 to Dec 7
$122 total
Dec 6 - Dec 7
Total with taxes and fees
8.4/10 Very Good! (387 reviews)
"No complaints Love this Hotel I will choose it every time Breakfast was great, alot to choose from Rooms were clean Staff was great aswell"
Reviewed on Nov 7, 2026

Holiday Inn Express & Suites Opelousas by IHG
5696 I-49 N Service Rd Opelousas LA
Fully refundable
$135 nightly
The price is $159 total per night from Nov 22 to Nov 23
$159 total
Nov 22 - Nov 23
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Opelousas Vacation Packages
Opelousas Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Lafayette Regional Airport (LFT) |
Population | 16,600 |
Max Temp Winter | 60ºF |
Max Temp Summer | 90ºF |
Top Sights | Louisiana Orphan Train Museum and St. Landry Catholic Church |
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.


















