Opelousas Vacations from $541
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Your Opelousas Vacation
There's no better way to embark on an adventure than with one of our vacation packages to Opelousas. The rich history and cultural experiences are a couple of the countless reasons to spend some time in this interesting city. Be sure to spend time sightseeing during your trip to Opelousas. Louisiana Orphan Train Museum and St. Landry Catholic Church are some well-known attractions to check out. Don't delay visiting this destination any longer. Your dream Opelousas vacation is a couple of clicks away with Expedia.
The Latest Opelousas vacation packages
Price found within the past 48 hours. Click for updated prices.
Evangeline A in Lafayette
McComb-Veazey
Price was $589, price is now $541 per person
$541
per person
Sep 26 - Sep 29
found 10 hours ago
Roundtrip non-stop flight included
Las Vegas (LAS) to Lafayette (LFT)
10/10 Exceptional! (1 review)
Such a cute little gem, right outside of downtown Lafayette. The house was lovely inside and out. The recent renovations and layout of the house makes it feel so much bigger than it is. The vaulted ceilings, and beautiful attention to details in the interior design made this a new place to stay when we visit!
Reviewed on May 12, 2025
Discover the most popular places to visit in Opelousas
Evangeline Downs Racetrack & Casino
Why not try your luck with a visit to Evangeline Downs Racetrack & Casino during your time in Opelousas? While in the area, you can find time to visit its casinos.
St. Landry Catholic Church
4.5/5(3 reviews)
Find out about the history of Opelousas when you spend time at St. Landry Catholic Church. While in the area, you can find time to visit its casinos.
Louisiana Orphan Train Museum
You can browse the exhibits at Louisiana Orphan Train Museum, a museum with a storied past, during your travels to Opelousas. While in the area, you can find time to visit its casinos.
Opelousas Hotel Deals
Days Inn & Suites by Wyndham Opelousas
5761 I-49 S Service Rd, Opelousas, LA
Fully refundableReserve now, pay when you stay
$66 nightly
The price is $76 total per night from Sep 1 to Sep 2
$76 total
Sep 1 - Sep 2
Total with taxes and fees
6.8/10 (663 reviews)
"The shower was a problem."
Reviewed on Jul 24, 2025
Evangeline Downs Hotel, Ascend Hotel Collection
2235 Creswell Ln Ext, Lot B, Opelousas, LA
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $120 total per night from Sep 7 to Sep 8
$120 total
Sep 7 - Sep 8
Total with taxes and fees
8/10 Very Good! (695 reviews)
"Everything was great and amazing 😍"
Reviewed on Aug 11, 2025
Spark by Hilton Opelousas
5454 I-49 North Service Rd., Opelousas, LA
Fully refundableReserve now, pay when you stay
$83 nightly
The price is $97 total per night from Sep 7 to Sep 8
$97 total
Sep 7 - Sep 8
Total with taxes and fees
7.4/10 Good! (360 reviews)
Spark
"This hotel was so clean and nice. I really enjoyed the room and was able to relax and get plently of rest. I would recommend."
Reviewed on Aug 17, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.