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Compare 1,817 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG

3.5 star property
9.4 out of 10, Exceptional, (817)
"The hotel is very well situated"
$108 nightly
The price is $130
Sep 6 - Sep 7
Total with taxes and fees
Holiday Inn Hotel and Suites Mexico Felipe Angeles Airport by IHG

Verticca Hotel

3.0 star property
9.4 out of 10, Exceptional, (183)
"Good place to stay "
$103 nightly
The price is $124
Sep 1 - Sep 2
Total with taxes and fees
Verticca Hotel

Lamartine Boutique Hotel Polanco

5.0 star property
10.0 out of 10, Exceptional, (15)
"Fantastic place. Beautiful, reasonable price and helpful staff."
$250 nightly
The price is $299
Sep 1 - Sep 2
Total with taxes and fees
Lamartine Boutique Hotel Polanco

Hotel Finca Las Hortensias

3.0 star property
8.2 out of 10, Very Good, (179)
"Front desk service was excellent, the food was delicious and the service from Saul was wonderful. "
$52 nightly
The price is $64
Sep 22 - Sep 23
Total with taxes and fees
Hotel Finca Las Hortensias

Edgar Allan Poe 227 By Ömora

3.5 star property
10.0 out of 10, Exceptional, (27)
"Will definitely stay here again. Can’t say one bad thing about this place. "
$88 nightly
The price is $105
Sep 1 - Sep 2
Total with taxes and fees
Edgar Allan Poe 227 By Ömora

HOTEL CASA KAVIA

2.0 star property
9.8 out of 10, Exceptional, (7)
"Small, contemporary hotel at a great location. The front desk staff is a little inexperienced, but they try to please. The hotel manager, Sr. Fernández, goes above and beyond to make you feel welcomed. We would definitely stay here again. "
$148 nightly
The price is $177
Sep 1 - Sep 2
Total with taxes and fees
HOTEL CASA KAVIA

Fiesta Inn Ecatepec

3.5 star property
8.8 out of 10, Excellent, (765)
"This property was amazing. It was my second time staying with them but in a different location and it didn’t disappoint. The staff were amazing and the location was great with anything you needed within walking distance. "
$81 nightly
The price is $101
Sep 5 - Sep 6
Total with taxes and fees
Fiesta Inn Ecatepec

UTOPIC Platón by ULIV

5.0 star property
9.6 out of 10, Exceptional, (68)
"Excellent stay, highly recommend."
$171 nightly
The price is $205
Sep 1 - Sep 2
Total with taxes and fees
UTOPIC Platón by ULIV

Mala Vecindad Centro Historico

3.0 star property
8.8 out of 10, Excellent, (62)
"Friendly, supportive staff members. The place has a very unique decoration, as well as a rooftop with an impressive view of the city. It’s a quiet and relaxing place to rest but also to enjoy with family and friends."
$32 nightly
The price is $38
Sep 5 - Sep 6
Total with taxes and fees
Mala Vecindad Centro Historico

City Express by Marriott Ciudad de México La Villa

3.0 star property
8.8 out of 10, Excellent, (1011)
"Staff are very nice and friendly. "
$69 nightly
The price is $82
Sep 6 - Sep 7
Total with taxes and fees
City Express by Marriott Ciudad de México La Villa

UTOPIC Campos Elíseos by ULIV

4.0 star property
9.4 out of 10, Exceptional, (553)
"Location of the hotel is amazing, with restaurants and entertainment in all nearby."
$180 nightly
The price is $215
Sep 28 - Sep 29
Total with taxes and fees
UTOPIC Campos Elíseos by ULIV

Downtown Treasure Place

2.5 star property
8.8 out of 10, Excellent, (653)
"This ok, it's very nice, it's beautiful, "
$21 nightly
The price is $25
Sep 1 - Sep 2
Total with taxes and fees
Downtown Treasure Place

UTOPIC Polanco by ULIV

4.5 star property
9.0 out of 10, Wonderful, (619)
"It’s a good place to stay, specially if going for business purposes"
$112 nightly
The price is $134
Sep 5 - Sep 6
Total with taxes and fees
UTOPIC Polanco by ULIV

Capitalia Antara Polanco

4.5 star property
9.0 out of 10, Wonderful, (111)
"My stay was very enjoyable, and Karen at the front desk was exceptional!"
$120 nightly
The price is $145
Sep 17 - Sep 18
Total with taxes and fees
Capitalia Antara Polanco

Fiesta Americana México Toreo

4.0 star property
9.6 out of 10, Exceptional, (1009)
"Very good room and amenities "
$128 nightly
The price is $158
Sep 5 - Sep 6
Total with taxes and fees
Fiesta Americana México Toreo

Hotel Brasilia

3.0 star property
9.0 out of 10, Wonderful, (1008)
"It was a fantastic experience"
$54 nightly
The price is $64
Sep 15 - Sep 16
Total with taxes and fees
Hotel Brasilia

KALI La Raza Mexico City

2.5 star property
9.4 out of 10, Exceptional, (165)
"I enjoyed my stay here. Would definitely recommend "
$56 nightly
The price is $67
Sep 1 - Sep 2
Total with taxes and fees
KALI La Raza Mexico City

Autoparador del Valle

3.0 star property
7.2 out of 10, Good, (5)
"Affordable nice room"
$29 nightly
The price is $35
Sep 1 - Sep 2
Total with taxes and fees
Autoparador del Valle

The Wild Oscar

4.0 star property
9.6 out of 10, Exceptional, (455)
"This is a great hotel in a lovely location. Polanco is The place to stay in Mexico City. Great staff and welcoming environment. "
$214 nightly
The price is $256
Sep 1 - Sep 2
Total with taxes and fees
The Wild Oscar

District Polanco by Lumina

9.4 out of 10, Exceptional, (110)
"The location is top, beautiful neighborhood with great options for dinning and the hotel staff was very sweet and helpful! "
$138 nightly
The price is $165
Sep 5 - Sep 6
Total with taxes and fees
District Polanco by Lumina
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Where can I find the best nightlife in Santa Cruz?
Santa Cruz, located in the State of Mexico, offers a quaint yet lively atmosphere for those looking to unwind and enjoy the local nightlife.

The vibrant Calle Juárez is a focal point for nightlife in Santa Cruz, lined with various bars and restaurants where you can savor delicious regional cuisine while sipping on refreshing cocktails. This street often features live music, creating an inviting ambiance great for a night out with friends or a romantic evening.

Additionally, the Plaza Principal serves as a wonderful gathering spot, especially during weekends when local events and performances take place. The surrounding bars and cafes come alive with activity, offering a great mix of entertainment options.

If you appreciate a more relaxed vibe, the nearby neighborhoods also have charming venues where you can enjoy a laid-back evening, perhaps with a glass of mezcal or local beer, while mingling with friendly locals.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Santa Cruz.
How can I save on a Santa Cruz hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Santa Cruz hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Santa Cruz hotel?
Prices for hotels in Santa Cruz often vary, but you can find a great deal from $25 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.