Photo by Southernmost Illinois Tourism Bureau

Find hotels in Southwest Illinois, IL from $59

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Compare 705 hotels, room rates, hotel reviews and availability. Most hotels are fully refundable.

Our top choices for Southwest Illinois hotels

Drury Inn & Suites St. Louis O'Fallon, IL
Restaurant

Drury Inn & Suites St. Louis O'Fallon, IL

3.0 star property
9.6 out of 10, Exceptional, (1000)
"Clean, friendly staff, easy check in, comfortable bed, great breakfast, close to airport "
$102 nightly
The price is $118
Sep 14 - Sep 15
Total with taxes and fees
Drury Inn & Suites St. Louis O'Fallon, IL
Holiday Inn Express Troy by IHG
Exterior

Holiday Inn Express Troy by IHG

2.5 star property
9.4 out of 10, Exceptional, (655)
"Great stay. "
$127 nightly
The price is $141
Sep 14 - Sep 15
Total with taxes and fees
Holiday Inn Express Troy by IHG
Best Western Plus MidAmerica Hotel
Standard Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave (Larger Room) | Pillowtop beds, desk, laptop workspace, blackout drapes

Best Western Plus MidAmerica Hotel

2.5 star property
9.0 out of 10, Wonderful, (1013)
"Extremely friendly staff, great location, safe for a solo traveler "
$112 nightly
The price is $124
Sep 3 - Sep 4
Total with taxes and fees
Best Western Plus MidAmerica Hotel
Seasons Inn & Suites Highland
1 bedroom, in-room safe, desk, iron/ironing board

Seasons Inn & Suites Highland

2.5 star property
8.0 out of 10, Very Good, (606)
"Friendly staff, spacious rooms, had a positive experience. "
$95 nightly
The price is $106
Sep 29 - Sep 30
Total with taxes and fees
Seasons Inn & Suites Highland
The Principal Hotel
Exterior

The Principal Hotel

3.5 star property
9.8 out of 10, Exceptional, (126)
"Perfect stay! "
$94 nightly
The price is $105
Sep 14 - Sep 15
Total with taxes and fees
The Principal Hotel
Quality Inn & Suites Vandalia near I-70 and Hwy 51
Seasonal outdoor pool, pool umbrellas, sun loungers

Quality Inn & Suites Vandalia near I-70 and Hwy 51

2.5 star property
8.4 out of 10, Very Good, (1001)
"Very nice establishment "
$69 nightly
The price is $75
Sep 24 - Sep 25
Total with taxes and fees
Quality Inn & Suites Vandalia near I-70 and Hwy 51
Comfort Inn & Suites Greenville I-70
1 bedroom, desk, blackout drapes, iron/ironing board

Comfort Inn & Suites Greenville I-70

2.5 star property
8.4 out of 10, Very Good, (399)
"good place to stay"
$94 nightly
The price is $105
Sep 21 - Sep 22
Total with taxes and fees
Comfort Inn & Suites Greenville I-70
Lighthouse Lodge
Front of property

Lighthouse Lodge

2.0 star property
8.6 out of 10, Excellent, (19)
"Excellent breakfast across the street at Funderburk’s!"
$87 nightly
The price is $92
Sep 3 - Sep 4
Total with taxes and fees
Lighthouse Lodge
Ramada by Wyndham Vandalia
Lobby

Ramada by Wyndham Vandalia

2.0 star property
7.8 out of 10, Good, (786)
"It was clean and the bed was comfortable. Yhe pillows sucked though. "
$70 nightly
The price is $76
Oct 1 - Oct 2
Total with taxes and fees
Ramada by Wyndham Vandalia
Bel Air Motel
Exterior

Bel Air Motel

3.5 star property
8.8 out of 10, Excellent, (175)
"Clean no frills motel, nice shower"
$82 nightly
The price is $91
Sep 3 - Sep 4
Total with taxes and fees
Bel Air Motel
Super 8 by Wyndham Greenville
Standard Room, 2 Queen Beds | Desk, iron/ironing board, free cribs/infant beds, rollaway beds

Super 8 by Wyndham Greenville

2.0 star property
8.0 out of 10, Very Good, (729)
"It’s not super fancy, as you’d expect, but the place was decent and seemed clean, the staff was very friendly and helpful, and the prices are decent if you need a quick stay. "
$63 nightly
The price is $70
Sep 17 - Sep 18
Total with taxes and fees
Super 8 by Wyndham Greenville
Best Western U. S. Inn
Standard Room, 2 Double Beds, Non Smoking | Desk, laptop workspace, iron/ironing board, free WiFi

Best Western U. S. Inn

2.5 star property
8.6 out of 10, Excellent, (378)
"Great staff service, clean room, confortable beds."
$110 nightly
The price is $120
Sep 3 - Sep 4
Total with taxes and fees
Best Western U. S. Inn
Red Lion Inn & Suites Pontoon Beach
Blackout drapes, free WiFi, bed sheets

Red Lion Inn & Suites Pontoon Beach

2.5 star property
7.8 out of 10, Good, (503)
"The hotel was a safe place to stay and the staff were nice. The location was noisy and hotel was very bare bones. "
$64 nightly
The price is $71
Sep 16 - Sep 17
Total with taxes and fees
Red Lion Inn & Suites Pontoon Beach
Comfort Suites Mount Vernon
Terrace/patio

Comfort Suites Mount Vernon

2.5 star property
8.8 out of 10, Excellent, (1001)
"Nice hotel. Would stay here again."
$109 nightly
The price is $123
Sep 3 - Sep 4
Total with taxes and fees
Comfort Suites Mount Vernon
Motel 6 Troy, IL
Deluxe Room, 2 Queen Beds, Non Smoking, Refrigerator & Microwave | Laptop workspace, free WiFi, bed sheets

Motel 6 Troy, IL

2.0 star property
7.6 out of 10, Good, (509)
"Good place"
$70 nightly
The price is $78
Sep 3 - Sep 4
Total with taxes and fees
Motel 6 Troy, IL
Holiday Inn Express & Suites Vandalia by IHG
Free daily full breakfast

Holiday Inn Express & Suites Vandalia by IHG

2.5 star property
8.8 out of 10, Excellent, (733)
"Clean and right off the highway."
$121 nightly
The price is $132
Sep 14 - Sep 15
Total with taxes and fees
Holiday Inn Express & Suites Vandalia by IHG
Walker's Bluff Casino Resort
Indoor pool, seasonal outdoor pool

Walker's Bluff Casino Resort

4.5 star property
9.4 out of 10, Exceptional, (370)
"Very nice room, nice scenery not an interstate running thru it"
$190 nightly
The price is $211
Sep 3 - Sep 4
Total with taxes and fees
Walker's Bluff Casino Resort
Red Bud Country Inn
Comfort Room | Private kitchen | Fridge, microwave, paper towels, dining tables

Red Bud Country Inn

2.5 star property
9.0 out of 10, Wonderful, (45)
"Nice staff, very clean, easy parking. "
$85 nightly
The price is $95
Sep 9 - Sep 10
Total with taxes and fees
Red Bud Country Inn
Super 8 by Wyndham O'Fallon
Deluxe Studio Suite, 1 King Bed, Non Smoking | Pillowtop beds, in-room safe, desk, laptop workspace

Super 8 by Wyndham O'Fallon

2.0 star property
7.4 out of 10, Good, (1000)
"Friendly staff and helpful "
$51 nightly
The price is $59
Sep 9 - Sep 10
Total with taxes and fees
Super 8 by Wyndham O'Fallon
Super 8 by Wyndham Belleville St. Louis Area
Desk, iron/ironing board, rollaway beds, free WiFi

Super 8 by Wyndham Belleville St. Louis Area

2.0 star property
7.4 out of 10, Good, (828)
"Nice property close to everything in the Belleville area. They have a very nice staff and I enjoyed staying here very much., "
$63 nightly
The price is $72
Sep 14 - Sep 15
Total with taxes and fees
Super 8 by Wyndham Belleville St. Louis Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Southwest Illinois, IL

Showing deals for:Sep 12 - Sep 14

Image gallery for Baymont by Wyndham Chester IL

Deluxe Studio Suite, 1 King Bed, Non Smoking | Jetted tub

Baymont by Wyndham Chester IL

2.5 star property
Chester
8.6/10Excellent (332 reviews)
15% off
$78 nightly
Price is $174
Total with taxes and fees
Baymont by Wyndham Chester IL
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Stay near popular Southwest Illinois attractions

Southern Illinois University
Campus Lake at Southern Illinois University in Carbondale, IL.

Southern Illinois University

Take a campus tour or just explore the area of Southern Illinois University, during your trip to Carbondale. Check out the shops and top-notch restaurants in this family-friendly area.

See properties in Southern Illinois University
Giant City State Park
Giant City State Park featuring climbing as well as an individual femail

Giant City State Park

Walk amid mystical woodland, admire geological wonders, go horseback riding and camp in the wilderness in the spectacular countryside of Southwest Illinois.

See properties in Giant City State Park

Learn more about Southwest Illinois

Explore a “natural city” of trees, enjoy incredible hilltop views, marvel at geological wonders and hop between small towns in this beautiful region.

See all hotels in Southwest Illinois
Southern Illinois which includes a lake or waterhole and forests
Photo by Southernmost Illinois Tourism Bureau
Open Photo by Southernmost Illinois Tourism Bureau

Top Southwest Illinois Hotel Reviews

The Principal Hotel

The Principal Hotel

10/10 Excellent
"Very clean place to stay. We would definitely come back. "
Sarah 4-night trip
Posted 4 days ago
The Principal Hotel

More cheap stays in Southwest Illinois

More cheap stays in Southwest Illinois

Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach

1240 E Chain Of Rocks Rd, Granite City, IL
$64 nightly
The price is $71 total per night from Sep 16 to Sep 17
$71 total
Sep 16 - Sep 17
Total with taxes and fees

Hotels in Southwest Illinois with star-rating

Hotels in Southwest Illinois with star-rating

Explore a world of travel with Expedia

Explore a world of travel with Expedia