$448 Cheap American Airlines flights Panama City (PTY) to Castries (SLU)

Scoring cheap one-way American Airlines flights from PTY to SLU from $448 on Expedia is simple --- just filter by "Price (lowest to highest)." Or check out our budget-friendly return fares from $1,281 for your next break.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

To grab affordable flights from PTY to SLU with American Airlines, start your search about one month before your planned departure. You can save 17% when you book your international tickets 18 to 29 days ahead instead of booking four to five months in advance. Another helpful tip? Booking on Sunday can lead to average savings of 17% compared to Friday (the most expensive day).**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Browse American Airlines's earliest flights from PTY to SLU by using the "Early Morning" and "Morning" filters. Not only will you arrive sooner, early departures are also 20% less likely to be canceled.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.