$126 Cheap Delta flights Columbus (CMH) to Knoxville (TYS)

View $126 flight on Wed, Nov 19, 2025Opens in a new window

$126 Cheap Delta flights Columbus (CMH) to Knoxville (TYS)

Prices were available within the past 7 days and start at $126 for one-way flights and $218 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Thu, Nov 27 - Sat, Dec 13
CMH
Columbus
TYS
Knoxville
$218 Roundtrip, found 3 days ago
$218
Roundtrip
found 3 days ago
Select Delta flight, departing Thu, Nov 27 from Columbus to Knoxville, returning Sat, Dec 13, priced at $218 found 3 days ago
Delta
Fri, Aug 8 - Mon, Aug 11
CMH
Columbus
TYS
Knoxville
$219 Roundtrip, just found
$219
Roundtrip
just found
Select Delta flight, departing Fri, Aug 8 from Columbus to Knoxville, returning Mon, Aug 11, priced at $219 just found
Delta
Tue, Jul 8 - Tue, Jul 22
CMH
Columbus
TYS
Knoxville
$244 Roundtrip, found 16 hours ago
$244
Roundtrip
found 16 hours ago
Select Delta flight, departing Tue, Jul 8 from Columbus to Knoxville, returning Tue, Jul 22, priced at $244 found 16 hours ago
Delta
Tue, Jul 8 - Tue, Jul 15
CMH
Columbus
TYS
Knoxville
$249 Roundtrip, found 16 hours ago
$249
Roundtrip
found 16 hours ago
Select Delta flight, departing Tue, Jul 8 from Columbus to Knoxville, returning Tue, Jul 15, priced at $249 found 16 hours ago
Delta
Wed, Sep 3 - Sat, Sep 6
CMH
Columbus
TYS
Knoxville
$253 Roundtrip, found 3 days ago
$253
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, Sep 3 from Columbus to Knoxville, returning Sat, Sep 6, priced at $253 found 3 days ago
Delta
Tue, Jul 22 - Sun, Aug 10
CMH
Columbus
TYS
Knoxville
$268 Roundtrip, found 3 hours ago
$268
Roundtrip
found 3 hours ago
Select Delta flight, departing Tue, Jul 22 from Columbus to Knoxville, returning Sun, Aug 10, priced at $268 found 3 hours ago
Flights from Columbus (CMH) to Knoxville (TYS)
Origin airport
John Glenn Columbus Intl.
Destination airport
McGhee Tyson
Airlines serving
American Airlines, Delta, United
Popular airline
Delta
Distance
295 mi

Frequently asked questions

How much is a Delta Air Lines flight from John Glenn Columbus Intl. Airport (CMH) to McGhee Tyson Airport (TYS)?
Set the "Price (lowest to highest)" filter on Expedia to find cheap Delta Air Lines return flights from $218 from CMH to TYS. Affordable one-way fares from $126 are also on offer.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
What is the cheapest month to fly from CMH to TYS with Delta Air Lines?
Look for one-way or return flights to Knoxville in January or December. You could find a cheap fare with Delta Air Lines during these off-peak travel months.
What is the cheapest time to book flights from John Glenn Columbus Intl. Airport (CMH) to McGhee Tyson Airport (TYS) with Delta Air Lines?
To find cheap Delta Air Lines fares from John Glenn Columbus Intl. Airport (CMH) to McGhee Tyson Airport (TYS), start searching one to three months before your planned departure. Securing domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also influence the cost. Sunday is generally the cheapest, while Monday is often the most expensive for domestic flights. You can save 6% on average by booking your journey on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.
Does Delta Air Lines fly nonstop from John Glenn Columbus Intl. Airport (CMH) to McGhee Tyson Airport (TYS)?
Use our "Nonstop" filter when browsing for direct Delta Air Lines flights from CMH to TYS. It's also an easy way to compare other airlines offering the same nonstop trip.
What is the earliest Delta Air Lines flight from CMH to TYS?
To find the earliest departure from CMH to TYS with Delta Air Lines, sort your results by "Morning" and "Early Morning." Booking an early flight generally means you'll experience fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports does Delta Air Lines fly into in Knoxville?
McGhee Tyson Airport (TYS) is the main Knoxville hub for Delta Air Lines flights from John Glenn Columbus Intl. Airport (CMH).
Why fly with Delta Air Lines from CMH to TYS?
Jetting off from CMH to TYS with Delta Air Lines means enjoying a host of benefits, such as a rewarding loyalty program and an excellent in-flight experience. Plus, when you book through Expedia, One Key™ members can collect OneKeyCash™* to use on select future travel purchases. That's on top of the Delta SkyMiles points you can earn with Delta Air Lines.*OneKeyCash™ disclaimer - OneKeyCash™ is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
Can I change or cancel my Delta Air Lines flight from John Glenn Columbus Intl. Airport (CMH) to McGhee Tyson Airport (TYS)?
Depending on your ticket type, a fee is typically charged if you change or cancel your booking more than 24 hours after confirmation. To find flexible fares, select our "Changes included" and "No cancel fee" boxes while searching for flights. For additional information on modifying or canceling your reservation, visit "Trips," select your flight and click on "Manage Booking."

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*Available to One Key members.