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$302 Cheap Flights from Gainesville (GNV) to Buffalo (BUF)

View $302 flight on Tue, Jun 30, 2026Opens in a new window

Popular airlines from Gainesville Regional Airport (GNV) to Buffalo Niagara Intl. Airport (BUF)

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Cheap Flights from Gainesville to Buffalo (GNV-BUF)

Prices were available within the past 7 days and start at $302 for one-way flights and $383 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Wed, Aug 12 - Wed, Aug 19
GNV
Gainesville
BUF
Buffalo
$383 Roundtrip, found 3 days ago
$383
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Aug 12 from Gainesville to Buffalo, returning Wed, Aug 19, priced at $383 found 3 days ago
Delta
Wed, Aug 12 - Wed, Aug 19
GNV
Gainesville
BUF
Buffalo
$383 Roundtrip, found 3 days ago
$383
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, Aug 12 from Gainesville to Buffalo, returning Wed, Aug 19, priced at $383 found 3 days ago
American Airlines
Wed, Aug 12 - Wed, Aug 19
GNV
Gainesville
BUF
Buffalo
$415 Roundtrip, found 3 days ago
$415
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Aug 12 from Gainesville to Buffalo, returning Wed, Aug 19, priced at $415 found 3 days ago
Delta
Wed, Aug 12 - Wed, Aug 19
GNV
Gainesville
BUF
Buffalo
$421 Roundtrip, found 3 days ago
$421
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, Aug 12 from Gainesville to Buffalo, returning Wed, Aug 19, priced at $421 found 3 days ago
Delta
Wed, Aug 5 - Mon, Aug 10
GNV
Gainesville
BUF
Buffalo
$425 Roundtrip, found 6 hours ago
$425
Roundtrip
found 6 hours ago
Select Delta flight, departing Wed, Aug 5 from Gainesville to Buffalo, returning Mon, Aug 10, priced at $425 found 6 hours ago
American Airlines
Fri, Sep 11 - Tue, Sep 15
GNV
Gainesville
BUF
Buffalo
$430 Roundtrip, found 17 hours ago
$430
Roundtrip
found 17 hours ago
Select American Airlines flight, departing Fri, Sep 11 from Gainesville to Buffalo, returning Tue, Sep 15, priced at $430 found 17 hours ago
American Airlines
Wed, Aug 12 - Wed, Aug 19
GNV
Gainesville
BUF
Buffalo
$463 Roundtrip, found 3 days ago
$463
Roundtrip
found 3 days ago
Select American Airlines flight, departing Wed, Aug 12 from Gainesville to Buffalo, returning Wed, Aug 19, priced at $463 found 3 days ago
American Airlines
Tue, Jul 28 - Tue, Aug 18
GNV
Gainesville
BUF
Buffalo
$466 Roundtrip, found 6 days ago
$466
Roundtrip
found 6 days ago
Select American Airlines flight, departing Tue, Jul 28 from Gainesville to Buffalo, returning Tue, Aug 18, priced at $466 found 6 days ago
American Airlines
Wed, May 5 - Sun, May 9
GNV
Gainesville
BUF
Buffalo
$482 Roundtrip, found 15 hours ago
$482
Roundtrip
found 15 hours ago
Select American Airlines flight, departing Wed, May 5 from Gainesville to Buffalo, returning Sun, May 9, priced at $482 found 15 hours ago
Delta
Wed, Aug 12 - Wed, Aug 19
GNV
Gainesville
BUF
Buffalo
$483 Roundtrip, found 3 days ago
$483
Roundtrip
found 3 days ago
Select Delta flight, departing Wed, Aug 12 from Gainesville to Buffalo, returning Wed, Aug 19, priced at $483 found 3 days ago

What you need to know for your flight from Gainesville Regional to Buffalo Niagara Intl.

Gainesville (GNV) to Buffalo (BUF) at a glance

Travel from Gainesville (GNV) to Buffalo (BUF) with a range of airlines offering convenient options on this domestic short-haul route. Explore your choices, from full-service carriers to budget-friendly alternatives, to find the best itinerary that aligns with your travel plans and budget. Check out essential details for flights from Gainesville Regional Airport to Buffalo Niagara International Airport as you plan your visit to Buffalo's iconic attractions and neighborhoods.

  • Fastest flight duration: around 3h 30m in-flight, plus roughly 1h 30m layover with one stop
  • Route distance: roughly 900 miles (1,450 km)
  • Flights per week: around 8 departures on average
  • Typical fares (one-way): economy tickets often range from $120–$415, depending on seasonality and how far ahead you book

Flights from Gainesville Regional Airport (GNV) to Buffalo Niagara International Airport (BUF)

Based on recent traveler bookings, here are the top airlines flying from Gainesville to Buffalo, commonly selected for their one-stop services. Notable layover options include Hartsfield-Jackson Atlanta International Airport (ATL), with about a 1-hour and 30-minute layover, and Charlotte-Douglas International Airport (CLT), offering approximately a 1-hour and 15-minute layover. This variety allows you to balance price, total travel time, and cabin class for the ideal itinerary.

  • Delta: This full-service airline provides convenient one-stop service, with one-way ticket prices generally falling between $125 and $425. Delta represents about 65% of the flights on this route, featuring an in-flight duration of 3 hours and 30 minutes, leading to an overall travel time of approximately 5 hours, including layover.
  • American Airlines: Another full-service option, American Airlines offers one-stop journeying with one-way fares that typically range from $125 to $345. It accounts for around 35% of departures on this route, with a flight time of 3 hours and 30 minutes, resulting in a total travel duration of close to 5 hours, inclusive of layover.

Alternative routes from Gainesville (GNV) to Buffalo (BUF)

  • Jacksonville to Buffalo (JAX-BUF): Jacksonville International Airport (JAX) is located about 66 miles from Gainesville Regional Airport (GNV). One-way economy fares for this route generally fall between $100 and $370, influenced by the time of year and how far in advance you book. Most flights on this route offer one-stop options, with common layovers occurring at Charlotte-Douglas International Airport (CLT) and Hartsfield-Jackson Atlanta International Airport (ATL). Major airlines like American Airlines and Delta frequently operate this route, with first-class service also available.
  • Gainesville to Rochester (GNV-ROC): Greater Rochester International Airport (ROC) lies approximately 56 miles from Buffalo Niagara International Airport (BUF). One-way economy fares on this route usually range from $120 to $475, depending on the season and the timing of your booking. Travelers can expect one-stop flights, with popular layover locations at Hartsfield-Jackson Atlanta International Airport (ATL) and Charlotte-Douglas International Airport (CLT). Delta and American Airlines are the primary carriers for this route.

How to find the best prices for flights from Gainesville (GNV) to Buffalo (BUF)

Getting some of the best deals on flights from Gainesville to Buffalo is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are typically found when booking within two weeks, although most travelers book their flights 2 to 8 weeks in advance. Morning departures between 5 a.m. and 12 p.m. tend to offer lower prices and are also the most popular flight times. Additionally, flying on Friday generally provides cheaper rates, though Monday remains the most popular travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Buffalo Niagara International Airport from Gainesville Regional Airport

Buffalo welcomes travelers from Gainesville with a range of transport options based on price, convenience, and proximity. Here's how to reach Buffalo efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Buffalo, with private rides that can be arranged in advance.
  • Car rental: Renting a car from Buffalo Niagara International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Buffalo Niagara International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From Buffalo Niagara International Airport, Buffalo-Depew Station, a train station, is located about 2.6 miles away by car, while University Station, a metro station, is situated approximately 6.5 miles away by car, providing convenient access to public transport options.

Frequently asked questions

How much does a flight from Gainesville, FL (GNV-Gainesville Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.) cost?
You can find cheap one-way flights from $302 and cheap return flights from $383 Gainesville, FL (GNV-Gainesville Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.) with Expedia. One-way flights usually range from $223 to $745, and return flights typically cost between $343 and $1378. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Gainesville, FL (GNV-Gainesville Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Gainesville, FL (GNV-Gainesville Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The cheapest month to fly from GNV to BUF is August when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Gainesville, FL (GNV-Gainesville Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Enter GNV to BUF and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Gainesville, FL (GNV-Gainesville Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
American Airlines is one of the cheapest airlines offering connecting flights from Gainesville (GNV) to Buffalo (BUF), with round-trip tickets starting from around $429 with a layover in Charlotte-Douglas Intl. (CLT). Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Gainesville, FL (GNV-Gainesville Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
To find a cheap flight from Gainesville, FL (GNV-Gainesville Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Gainesville, FL (GNV-Gainesville Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Gainesville, FL (GNV-Gainesville Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The earliest flight from Gainesville Regional (GNV) to Buffalo Niagara International (BUF) usually departs at around 5:00 AM, operated by American Airlines. This seasonal service is available in May, allowing you to arrive in Buffalo early and enjoy the day ahead. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Gainesville, FL (GNV-Gainesville Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The most popular departure times for flights from Gainesville, FL (GNV) to Buffalo, NY (BUF) are in the early morning, from 6am to 9am. About 36% of passengers prefer this time window. Many major carriers, including Delta Air Lines and United Airlines, offer flights during this window. This timing is favored as it allows you to arrive in Buffalo with plenty of time to start your day.
How long does it take to fly from Gainesville, FL (GNV-Gainesville Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Flights from GNV to BUF with one stop typically take around 5 hours, covering approximately 936 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Gainesville, FL (GNV-Gainesville Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
First class seats are offered on the GNV to BUF route with Delta Air Lines and American Airlines.
How do I earn miles on a Gainesville, FL (GNV-Gainesville Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight with Expedia?
It's easy to earn miles on a Gainesville, FL (GNV-Gainesville Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Buffalo from Gainesville Regional (GNV)?
If you're planning to travel to Buffalo from Gainesville Regional (GNV), you can fly into Buffalo Niagara Intl. (BUF) Some flights may connect through major hubs like Hartsfield-Jackson Atlanta Intl. (ATL), Charlotte-Douglas Intl. (CLT), Miami Intl. (MIA) before reaching Buffalo. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Gainesville, FL (GNV-Gainesville Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.) at the last minute?
Typically, booking a last minute flight from Gainesville, FL (GNV-Gainesville Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Gainesville, FL (GNV-Gainesville Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight and hotel package?
Securing a Gainesville, FL (GNV-Gainesville Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.) Buffalo Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Gainesville, FL (GNV-Gainesville Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
If you booked your Gainesville, FL (GNV-Gainesville Regional) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Gainesville Regional
Destination airport
Buffalo Niagara Intl.
Airlines serving
American Airlines, Delta
Roundtrip price
$382
Distance
936 mi

Book with confidence

Gainesville to Buffalo Flights

The cheapest times to fly from Gainesville to Buffalo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Gainesville to Buffalo are during the month of August. You can find some of the cheapest flights from Gainesville to Buffalo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Gainesville to Buffalo

Sunday is one of the best days to book for cheap flights from Gainesville to Buffalo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Gainesville to Buffalo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Gainesville to Buffalo in 2026. You can also book with separate airlines for your outbound and return journeys, from $302 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Gainesville to Buffalo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Gainesville to Buffalo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Gainesville to Buffalo Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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