$5,706 Cheap Flights from Johannesburg (JNB) to Tupelo (TUP)

View $5,706 flight on Thu, Nov 20, 2025Opens in a new window

Popular airlines from O.R. Tambo Intl. Airport (JNB) to Tupelo, MS (TUP-Tupelo Regional)

Cheap Flights from Johannesburg to Tupelo (JNB-TUP)

Prices were available within the past 7 days and start at $5,706 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frequently asked questions

How much does a flight from O.R. Tambo Intl. Airport (JNB) to Tupelo Regional Airport (TUP) cost?
Grab a cheap one-way flight from $5,706 or cheap return flight from O.R. Tambo Intl. Airport (JNB) to Tupelo Regional Airport (TUP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from O.R. Tambo Intl. Airport (JNB) to Tupelo Regional Airport (TUP)?
is the most affordable month to fly from JNB to TUP. Planning your trip for the off-season is often the key to finding better fares.
What is the cheapest airline that flies from O.R. Tambo Intl. Airport (JNB) to Tupelo Regional Airport (TUP)?
Expedia's filter tool lets you easily compare travel time, airlines and fares all in one place. Customize the search to your preferences, then sort by "Price (lowest to highest)" to see which carrier offers the cheapest JNB to TUP flight.
How many flights per day from O.R. Tambo Intl. Airport (JNB) to Tupelo Regional Airport (TUP)?
There are no daily direct flights available from O.R. Tambo Intl. Airport (JNB) to Tupelo Regional Airport (TUP). But you can opt for flights with layovers. Filter your search on Expedia to include one or two stops, and you'll be soaring above the clouds in no time at all.
What day of the week has the most flights from JNB to TUP?
Usually you'll find the largest variety of flight choices on a Friday. Tuesdays tend to be the quietest.* However, this can change based on the time of year, airline and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from O.R. Tambo Intl. Airport (JNB) to Tupelo Regional Airport (TUP)?
To avoid possible delays on the O.R. Tambo Intl. Airport (JNB) to Tupelo Regional Airport (TUP) route, aim to travel before 3 PM. Departures after this hour are 22% more likely to be canceled.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from O.R. Tambo Intl. Airport (JNB) to Tupelo Regional Airport (TUP) last-minute?
Holding off until just before your trip to book a flight from JNB to TUP generally means paying more. Although you may find some last-minute deals, there's no guarantee. Allow some flexibility in your schedule to boost your chances of snagging a bargain.
Is it cheaper to book a JNB to TUP flight and hotel package?
Compared with arranging hotels and flights separately, booking a JNB to TUP flight and hotel package with Expedia could lead to significant savings. Better yet, having everything in one place takes the hassle out of planning your trip. Simply secure your flights and select from our wide range of stays, then tailor your trip with other add-ons like tours, car rentals and activities.
Can I cancel or change the date of my flight from O.R. Tambo Intl. Airport (JNB) to Tupelo Regional Airport (TUP)?
If you booked your JNB to TUP flight in the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the fare type you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for more information.

Travel information

Origin airport
O.R. Tambo Intl.
Destination airport
Tupelo Regional
Distance
8690 mi

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Johannesburg to Tupelo Flights

The cheapest times to fly from Johannesburg to Tupelo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Johannesburg to Tupelo are during the month of . You can find some of the cheapest flights from Johannesburg to Tupelo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Johannesburg to Tupelo

Sunday is one of the best days to book for cheap flights from Johannesburg to Tupelo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Johannesburg to Tupelo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Johannesburg to Tupelo in 2025. You can also book with separate airlines for your outbound and return journeys, from $5,706 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Johannesburg to Tupelo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Johannesburg to Tupelo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Johannesburg to Tupelo Flights

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*Available to One Key members.