$260 Cheap Flights from La Crosse (LSE) to Portland (PWM)

View $260 flight on Wed, Aug 27, 2025Opens in a new window

Popular airlines from La Crosse, WI (LSE-La Crosse Municipal) to Portland Intl. Jetport Airport (PWM)

Cheap Flights from La Crosse to Portland (LSE-PWM)

Prices were available within the past 7 days and start at $260 for one-way flights and $440 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Mon, Sep 22 - Wed, Oct 1
LSE
La Crosse
PWM
Portland
$440 Roundtrip, found 2 days ago
$440
Roundtrip
found 2 days ago
Select American Airlines flight, departing Mon, Sep 22 from La Crosse to Portland, returning Wed, Oct 1, priced at $440 found 2 days ago
American Airlines
Sun, Sep 7 - Sat, Sep 13
LSE
La Crosse
PWM
Portland
$475 Roundtrip, found 2 days ago
$475
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sun, Sep 7 from La Crosse to Portland, returning Sat, Sep 13, priced at $475 found 2 days ago
American Airlines
Sun, Sep 7 - Sat, Sep 13
LSE
La Crosse
PWM
Portland
$480 Roundtrip, found 2 days ago
$480
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sun, Sep 7 from La Crosse to Portland, returning Sat, Sep 13, priced at $480 found 2 days ago
American Airlines
Wed, Sep 24 - Sat, Oct 4
LSE
La Crosse
PWM
Portland
$488 Roundtrip, found 14 hours ago
$488
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Wed, Sep 24 from La Crosse to Portland, returning Sat, Oct 4, priced at $488 found 14 hours ago
American Airlines
Tue, Sep 23 - Sat, Oct 4
LSE
La Crosse
PWM
Portland
$493 Roundtrip, found 14 hours ago
$493
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Tue, Sep 23 from La Crosse to Portland, returning Sat, Oct 4, priced at $493 found 14 hours ago
American Airlines
Sun, Sep 7 - Sat, Sep 13
LSE
La Crosse
PWM
Portland
$501 Roundtrip, found 2 days ago
$501
Roundtrip
found 2 days ago
Select American Airlines flight, departing Sun, Sep 7 from La Crosse to Portland, returning Sat, Sep 13, priced at $501 found 2 days ago
American Airlines
Wed, Sep 24 - Wed, Oct 8
LSE
La Crosse
PWM
Portland
$503 Roundtrip, found 14 hours ago
$503
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Wed, Sep 24 from La Crosse to Portland, returning Wed, Oct 8, priced at $503 found 14 hours ago
American Airlines
Tue, Sep 16 - Sat, Sep 20
LSE
La Crosse
PWM
Portland
$508 Roundtrip, found 1 day ago
$508
Roundtrip
found 1 day ago
Select American Airlines flight, departing Tue, Sep 16 from La Crosse to Portland, returning Sat, Sep 20, priced at $508 found 1 day ago
American Airlines
Fri, Oct 17 - Sun, Oct 26
LSE
La Crosse
PWM
Portland
$513 Roundtrip, found 3 days ago
$513
Roundtrip
found 3 days ago
Select American Airlines flight, departing Fri, Oct 17 from La Crosse to Portland, returning Sun, Oct 26, priced at $513 found 3 days ago
American Airlines
Wed, Aug 13 - Wed, Aug 20
LSE
La Crosse
PWM
Portland
$518 Roundtrip, found 14 hours ago
$518
Roundtrip
found 14 hours ago
Select American Airlines flight, departing Wed, Aug 13 from La Crosse to Portland, returning Wed, Aug 20, priced at $518 found 14 hours ago
Flights from La Crosse (LSE) to Portland (PWM)
Origin airport
La Crosse Municipal
Destination airport
Portland Intl. Jetport
Airlines serving
American Airlines
Roundtrip price
$440
Distance
1042 mi

La Crosse to Portland Flights

The cheapest times to fly from La Crosse to Portland

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from La Crosse to Portland are during the month of September. You can find some of the cheapest flights from La Crosse to Portland with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from La Crosse to Portland

Sunday is one of the best days to book for cheap flights from La Crosse to Portland: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from La Crosse to Portland

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from La Crosse to Portland in 2025. You can also book with separate airlines for your outbound and return journeys, from $260 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap La Crosse to Portland flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your La Crosse to Portland airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from La Crosse Municipal Airport (LSE) to Portland Intl. Jetport Airport (PWM) cost?
Lock in a cheap one-way flight from $260 or cheap return flight from $440 from La Crosse Municipal Airport (LSE) to Portland Intl. Jetport Airport (PWM) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from La Crosse Municipal Airport (LSE) to Portland Intl. Jetport Airport (PWM)?
The cheapest month to fly from LSE to PWM is September, when demand is low. Off-peak season is usually when airlines offer better prices between these airports.
What is the cheapest airline that flies from La Crosse Municipal Airport (LSE) to Portland Intl. Jetport Airport (PWM)?
Use the filters on Expedia to compare airlines and find the cheapest carrier that'll take you from LSE to PWM. Then, sort your results by "Price (lowest to highest)" to snap up a great deal.
How many flights per day from La Crosse Municipal Airport (LSE) to Portland Intl. Jetport Airport (PWM)?
You'll need to hop on a flight with a layover when traveling from La Crosse Municipal Airport (LSE) to Portland Intl. Jetport Airport (PWM). Direct flights don't operate daily on this route. However, just filter your search to include one or more stops to find the best option for your trip.
What day of the week has the most flights from LSE to PWM?
Friday is usually the busiest day for flights, while Tuesday is often the quietest.* Just remember that flight schedules can change based on a range of factors, including the carrier and season.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from La Crosse Municipal Airport (LSE) to Portland Intl. Jetport Airport (PWM)?
To arrive at Portland Intl. Jetport Airport (PWM) without delays, opt for a flight that leaves La Crosse Municipal Airport (LSE) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this hour.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from La Crosse Municipal Airport (LSE) to Portland Intl. Jetport Airport (PWM) last-minute?
Booking your flight from LSE to PWM right before your journey is usually more expensive. But if you're flexible with your departure times and dates, you could bag a cheap last-minute fare.
Is it cheaper to book a LSE to PWM flight and hotel package?
You'll generally save money by securing a LSE to PWM flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's easy to manage everything in one convenient place. After choosing your ideal accommodations and flights, consider adding extras such as activities, car rentals and tours.
Can I cancel or change the date of my flight from La Crosse Municipal Airport (LSE) to Portland Intl. Jetport Airport (PWM)?
Generally, it's possible to reschedule or cancel your LSE to PWM flight. However, if it's been more than 24 hours since booking, additional fees may apply. Refer to your airline's policies in your itinerary to see what changes are possible and whether any costs are involved. You'll also find more information on our Customer Service portal.

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*Available to One Key members.