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$159 Cheap Flights from Memphis (MEM) to Buffalo (BUF)

View $159 flight on Thu, Sep 17, 2026Opens in a new window

Popular airlines from Memphis International Airport (MEM) to Buffalo Niagara Intl. Airport (BUF)

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Cheap Flights from Memphis to Buffalo (MEM-BUF)

Prices were available within the past 7 days and start at $159 for one-way flights and $273 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Thu, Sep 17 - Wed, Sep 23
MEM
Memphis
BUF
Buffalo
$273 Roundtrip, found 5 days ago
$273
Roundtrip
found 5 days ago
Select American Airlines flight, departing Thu, Sep 17 from Memphis to Buffalo, returning Wed, Sep 23, priced at $273 found 5 days ago
Delta
Thu, Sep 17 - Wed, Sep 23
MEM
Memphis
BUF
Buffalo
$273 Roundtrip, found 5 days ago
$273
Roundtrip
found 5 days ago
Select Delta flight, departing Thu, Sep 17 from Memphis to Buffalo, returning Wed, Sep 23, priced at $273 found 5 days ago
Delta
Thu, Sep 17 - Wed, Sep 23
MEM
Memphis
BUF
Buffalo
$283 Roundtrip, found 5 days ago
$283
Roundtrip
found 5 days ago
Select Delta flight, departing Thu, Sep 17 from Memphis to Buffalo, returning Wed, Sep 23, priced at $283 found 5 days ago
Southwest Airlines
Sat, Oct 10 - Wed, Oct 14
MEM
Memphis
BUF
Buffalo
$285 Roundtrip, found 6 days ago
$285
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Sat, Oct 10 from Memphis to Buffalo, returning Wed, Oct 14, priced at $285 found 6 days ago
Southwest Airlines
Sat, Oct 10 - Wed, Oct 14
MEM
Memphis
BUF
Buffalo
$290 Roundtrip, found 6 days ago
$290
Roundtrip
found 6 days ago
Select Southwest Airlines flight, departing Sat, Oct 10 from Memphis to Buffalo, returning Wed, Oct 14, priced at $290 found 6 days ago
American Airlines
Thu, Oct 1 - Sat, Oct 3
MEM
Memphis
BUF
Buffalo
$297 Roundtrip, found 5 days ago
$297
Roundtrip
found 5 days ago
Select American Airlines flight, departing Thu, Oct 1 from Memphis to Buffalo, returning Sat, Oct 3, priced at $297 found 5 days ago
Southwest Airlines
Tue, Aug 4 - Sat, Aug 8
MEM
Memphis
BUF
Buffalo
$302 Roundtrip, found 5 days ago
$302
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Tue, Aug 4 from Memphis to Buffalo, returning Sat, Aug 8, priced at $302 found 5 days ago
Delta
Thu, Oct 1 - Sat, Oct 3
MEM
Memphis
BUF
Buffalo
$308 Roundtrip, found 5 days ago
$308
Roundtrip
found 5 days ago
Select Delta flight, departing Thu, Oct 1 from Memphis to Buffalo, returning Sat, Oct 3, priced at $308 found 5 days ago
Southwest Airlines
Thu, Oct 1 - Sat, Oct 3
MEM
Memphis
BUF
Buffalo
$308 Roundtrip, found 5 days ago
$308
Roundtrip
found 5 days ago
Select Southwest Airlines flight, departing Thu, Oct 1 from Memphis to Buffalo, returning Sat, Oct 3, priced at $308 found 5 days ago
United
Tue, Jul 7 - Tue, Jul 14
MEM
Memphis
BUF
Buffalo
$317 Roundtrip, found 2 days ago
$317
Roundtrip
found 2 days ago
Select United flight, departing Tue, Jul 7 from Memphis to Buffalo, returning Tue, Jul 14, priced at $317 found 2 days ago

Alternative airports near Buffalo

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Buffalo Niagara Intl. BUF. Cheapest and Closest option available. Average driving time to city center is 16 minutes. Flights from $457
BUF
Buffalo Niagara Intl.
CheapestClosest
Average driving time to city center16 min
Flights from $457

What you need to know for your flight from Memphis Intl. to Buffalo Niagara Intl.

Memphis (MEM) to Buffalo (BUF) at a glance

Embark on your journey from Memphis (MEM) to Buffalo (BUF) with a range of airlines available for this popular domestic short-haul route. Explore options from both full-service and low-cost carriers to discover flights that align with your budget and schedule while you plan your visit to Buffalo’s iconic attractions and vibrant neighborhoods. Get all the essential information for flights departing from Memphis International Airport (MEM) to Buffalo Niagara International Airport (BUF).

  • Fastest flight duration: around 3h 30m in-flight, plus roughly 1 hour layover with one stop
  • Route distance: roughly 800 miles (1,290 km)
  • Flights per week: around 9 departures on average
  • Typical fares (one-way): economy tickets often range from $120–$470, depending on seasonality and how far ahead you book

Flights from Memphis International Airport (MEM) to Buffalo Niagara International Airport (BUF)

Based on the latest traveler bookings, here are the top airlines favored for one-stop flights from Memphis to Buffalo. Common layover points include Hartsfield-Jackson Atlanta International Airport (ATL, approximately 1 hour), Detroit Metropolitan Wayne County Airport (DTW, about 1 hour), and Charlotte-Douglas International Airport (CLT, around 1 hour). These options allow you to balance price, overall travel time, and cabin class, helping you create the ideal travel itinerary.

  • Delta: As a leading full-service airline, Delta provides one-stop service with one-way fares generally priced between $130 and $470. This carrier represents about 40% of departures on this route, featuring an in-flight duration of 3 hours and 30 minutes, with the entire travel time nearing 4 hours and 30 minutes (including layover).
  • American Airlines: Another full-service option, American Airlines also offers one-stop flights, with one-way ticket prices typically ranging from $120 to $480. Approximately 34% of departures on this route are with American, and travelers can expect an in-flight time of 3 hours and 30 minutes, totaling around 4 hours and 30 minutes for the journey (including layover).
  • Southwest Airlines: This low-cost airline provides one-stop service, with one-way fares usually falling between $120 and $395. Southwest accounts for about 18% of departures on this route, featuring an in-flight duration of 3 hours and 30 minutes and a total travel time of roughly 4 hours and 30 minutes (including layover).
  • United: Offering one-stop service, United is a full-service carrier with one-way fares typically ranging from $180 to $480. It constitutes about 8% of departures on this route, and passengers can anticipate an in-flight time of 3 hours and 30 minutes, with an overall journey duration of around 4 hours and 30 minutes (including layover).

Travelers flying from Memphis to Buffalo can enhance their journey by upgrading to first class with American Airlines, which provides premium service on this route.

Best time to fly from Memphis (MEM) to Buffalo (BUF)

The most popular months for travelers flying from Memphis to Buffalo are March, April, and July, when peak temperatures in Buffalo reach up to 72°F in July. If you prefer quieter travel, consider December, the least busy and relatively cheaper time to visit with fewer crowds and temperatures around 33.1°F. For better deals, October usually offers the lowest average one-way fare around $201. Flight availability peaks in June, July, and December, with approximately 11 flights per week, making it easier to find convenient departure times. January and February have the fewest flights, with approximately 7 flights per week.

  • Cheapest time to fly: October usually offers good deals with average one-way fare around $201, roughly 16% cheaper than the yearly average.
  • More budget-friendly months to fly: August, December, and September typically offer average one-way fares of around $204.
  • Most flight options: June, July, and December have the highest number of flights from Memphis to Buffalo, with approximately 11 flights per week, giving you more flexibility in scheduling your trip.
calendar iconMonthtemperature iconTemperaturecrowd level iconDemandflights iconWeekly Flightsprice iconAverage one-way Fare
January25.5°F (-3.6°C)Low7$353
February26.1°F (-3.3°C)Low7$252
March34.3°F (1.3°C)High9$253
April45.0°F (7.2°C)High8$309
May57.7°F (14.3°C)Average9$221
June66.0°F (18.9°C)Average11$236
July72.0°F (22.2°C)High11$220
August70.7°F (21.5°C)Average9$203
September64.6°F (18.1°C)Average10$206
October53.2°F (11.8°C)Average8$201
November41.4°F (5.2°C)Average9$250
December33.1°F (0.6°C)Low11$204

*Average one-way fare is based on Expedia flight booking data from January 2025 to April 2026 for the specified route and travel class and may change depending on availability, dates, and demand.

Alternative route from Memphis (MEM) to Buffalo (BUF)

  • Memphis to Rochester (MEM-ROC): Greater Rochester International Airport (ROC) is approximately 56 miles from Buffalo Niagara International Airport (BUF). On this route, one-way economy fares generally fall between $120 and $445, influenced by the season and how far in advance you book. Flights on this path usually involve one-stop options, with common layover points at Hartsfield-Jackson Atlanta International Airport (ATL) and Charlotte-Douglas International Airport (CLT). Major airlines servicing this route include American Airlines and Delta, with first-class service also available.

How to find the best prices for flights from Memphis (MEM) to Buffalo (BUF)

Getting some of the best deals on flights from Memphis to Buffalo is all about timing and flexibility. Here are some key tips to help you save:

  1. Best times to book and fly: cheaper fares are usually available when booking 2-8 weeks in advance, coinciding with when most travelers make their reservations. Morning departures, specifically from 5 am to 12 pm, often provide lower prices and are popular flight times. Additionally, flying on Wednesdays can result in both cheaper fares and is the most favored travel day.
  2. Set up price alerts: stay updated on price changes by using Expedia's Price Tracker. Receive alerts when fares drop for your selected route.
  3. Bundle and save: bundle your flight and hotel to save on Expedia, or unlock a hotel deal after booking your flight.*
  4. Compare flight options: use Expedia's search tool to compare airlines, routes, direct vs. non-direct flights, and flight times. You can also sort by price to find the most affordable options.
  5. Stay flexible with dates: being open to different travel days can sometimes help you find better prices on flights and hotels.
  6. Think about luggage: nowadays, it's important to check the airline's baggage policies to find the best value. That may be paying for an additional carry-on bag or booking a ticket with checked luggage included. Either way, double-check your allowance before confirming your booking to avoid excess baggage fees at the airport.

*Members only. Savings vary and are not available on all bundles. Select hotels.

Arriving at Buffalo Niagara International Airport from Memphis International Airport

Buffalo welcomes travelers from Memphis with a range of transport options based on price, convenience, and proximity. Here's how to reach Buffalo efficiently:

  • Hotel transfer: Transfers offer a convenient way to reach your hotel in Buffalo, with private rides that can be arranged in advance.
  • Car rental: Renting a car from Buffalo Niagara International Airport is a great option if you plan to explore and sightsee beyond the city. Browse cheap car rentals at Buffalo Niagara International Airport on Expedia.
  • Taxi/ride-hailing: Taxis and ride-hailing services may be available from designated pickup areas outside the terminal, check locally on arrival.
  • Public transportation: From Buffalo Niagara International Airport, Buffalo-Depew Station, a train station, is located about 2.6 miles away by car, while University Station, a metro station, is situated approximately 6.5 miles away by car, providing convenient access to various transport options.

Frequently asked questions

How much does a flight from Memphis, TN (MEM-Memphis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) cost?
You can find cheap one-way flights from $159 and cheap return flights from $273 Memphis, TN (MEM-Memphis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) with Expedia. One-way flights generally range between $171 and $910, and roundtrip flights usually range from $322 to $1147. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Memphis, TN (MEM-Memphis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) ticket fares go up or down.*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.
What is the cheapest month to fly from Memphis, TN (MEM-Memphis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The cheapest month to fly from MEM to BUF is September when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route.
Which airlines fly direct from Memphis, TN (MEM-Memphis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Enter MEM to BUF and your travel dates, then apply the 'Nonstop' filter to see only direct flights.
What is the cheapest airline that flies from Memphis, TN (MEM-Memphis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
American Airlines is one of the cheapest airlines offering connecting flights from Memphis (MEM) to Buffalo (BUF), with round-trip tickets starting from around $319. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget.*Prices based on flights available on Expedia in the last year.
How do I find cheap flights from Memphis, TN (MEM-Memphis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
To find a cheap flight from Memphis, TN (MEM-Memphis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Memphis, TN (MEM-Memphis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
What is the earliest flight from Memphis, TN (MEM-Memphis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The earliest flight from Memphis International Airport (MEM) to Buffalo Niagara International Airport (BUF) typically departs at around 5:00 AM, operated by American Airlines. This is a seasonal service active in December, allowing you to start your day early and maximize your time in Buffalo. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What are the most popular departure times for flights from Memphis, TN (MEM-Memphis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The most popular departure times for flights from Memphis, TN (MEM) to Buffalo, NY (BUF) are from 6am to 9am. About 36% of passengers prefer this time window. Airlines such as American Airlines, Delta Airlines, and United Airlines operate flights during this time. This timing works well as it allows you to start your day in Memphis before heading to the airport.
How long does it take to fly from Memphis, TN (MEM-Memphis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
A flight from MEM to BUF with a layover takes around 5 hours, with the route covering approximately 812 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Memphis, TN (MEM-Memphis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
You can fly first class between MEM and BUF. First class cabins are available on:

  • American Airlines
  • Delta Air Lines
  • United Airlines

How do I earn miles on a Memphis, TN (MEM-Memphis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight with Expedia?
It's easy to earn miles on a Memphis, TN (MEM-Memphis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia.*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Buffalo from Memphis Intl. (MEM)?
If you're planning to travel to Buffalo from Memphis Intl. (MEM), you can fly into Buffalo Niagara Intl. (BUF) Some flights may connect through major hubs like O'Hare Intl. (ORD), George Bush Intercontinental (IAH), Charlotte-Douglas Intl. (CLT) before reaching Buffalo. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Memphis, TN (MEM-Memphis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) at the last minute?
Typically, booking a last minute flight from Memphis, TN (MEM-Memphis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Memphis, TN (MEM-Memphis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight and hotel package?
Securing a Memphis, TN (MEM-Memphis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) Buffalo Vacation Packages is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Memphis, TN (MEM-Memphis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
If you booked your Memphis, TN (MEM-Memphis Intl.) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
Memphis Intl.
Destination airport
Buffalo Niagara Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$272
Distance
812 mi

Book with confidence

Memphis to Buffalo Flights

The cheapest times to fly from Memphis to Buffalo

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Memphis to Buffalo are during the month of September. You can find some of the cheapest flights from Memphis to Buffalo with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Memphis to Buffalo

Sunday is one of the best days to book for cheap flights from Memphis to Buffalo: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Memphis to Buffalo

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Memphis to Buffalo in 2026. You can also book with separate airlines for your outbound and return journeys, from $159 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Memphis to Buffalo flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Memphis to Buffalo airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Memphis to Buffalo Flights

*Flight schedules are subject to change.

*Available to One Key members.

 

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