--- title: "Panama City to Cusco cheap flights from $486 (PTY to CUZ) - Expedia" description: "Book cheap Flights from Panama City (PTY) to Cusco (CUZ) start at $486 for one-way and $587 for round trip. Earn your airline miles on top of our rewards!" canonical: "https://www.expedia.com/lp/flights/pty/cuz/panama-city-to-cusco" language: en-US market: US currency: USD prices_as_of: 2026-11-13T00:53:26Z --- # $486 Cheap Flights from Panama City (PTY) to Cusco (CUZ) ![Machu Picchu, an ancient Incan city, nestled in a mountainous valley with terraced fields and steep cliffs.](https://images.trvl-media.com/place/178042/4d0a0510-b7bd-4bb8-bfef-af8ffd62296d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) [View $486 flight on Mon, Nov 30, 2026](https://www.expedia.com/Flights-Search?leg1=from:PTY,to:CUZ,departure:11/30/2026TANYT&trip=oneway&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:485.55&airProductToken=AQplCjAIwawBEgI1NxjvxAEgwTMo7smeAzDSyp4DOExAAFgBagVMSUdIVHIITEVPQjFCUkIKMQjBrAESAzEwNRjBMyCCzQEorNCeAzD50Z4DOExAAVgBagVMSUdIVHIITEVPQjFCUkISCggBEAEYASoCQVYYASIECAEQASgCKAMoBDAB) ## Popular airlines from Tocumen Intl. Airport (PTY) to Alejandro Velasco Astete Intl. Airport (CUZ) [Avianca](https://www.expedia.com/Flights-Search?leg1=from:PTY,to:CUZ,departure:11/27/2026TANYT&leg2=from:CUZ,to:PTY,departure:12/4/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AV"}}]) ## Cheap Flights from Panama City to Cusco (PTY-CUZ) Prices were available within the past 7 days and start at $486 for one-way flights and $587 for roundtrip, for the period specified. Prices and availability are subject to change. All deals One way Roundtrip [Select Avianca flight, departing Thu, Feb 4 from Panama City to Cusco, returning Thu, Feb 11, priced at $587 Found 5 hours ago](https://www.expedia.com/Flights-Search?leg1=from:PTY,to:CUZ,departure:2/4/2027TANYT&leg2=from:CUZ,to:PTY,departure:2/11/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:586.42&airProductToken=AQplCjAIwawBEgI1ORjvxAEgwTMoyaykAzCtraQDOFBAAFgBagVMSUdIVHIIUEVBQjFCUkIKMQjBrAESAzEwNRjBMyCCzQEo7LakAzC5uKQDOFBAAVgBagVMSUdIVHIIUEVBQjFCUkIKZQoxCMGsARIDMTA0GILNASDBMyjS%5FqQDMKmApQM4UEAAWAFqBUxJR0hUcghQRUFCMUJSQgowCMGsARICNTgYwTMg78QBKJ-FpQMwkoalAzhQQAFYAWoFTElHSFRyCFBFQUIxQlJCEgoIARABGAEqAkFWGAEiBAgBEAEoAigDKAQwAQ) Thu, Feb 4 - Thu, Feb 11 · PTY · CUZ · Roundtrip [Select Avianca flight, departing Thu, Feb 4 from Panama City to Cusco, returning Thu, Feb 11, priced at $591 Found 5 hours ago](https://www.expedia.com/Flights-Search?leg1=from:PTY,to:CUZ,departure:2/4/2027TANYT&leg2=from:CUZ,to:PTY,departure:2/11/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:590.62&airProductToken=AQppCjIIwawBEgI1ORjvxAEgwTMoyaykAzCtraQDOFNAAFgBagdDTEFTU0lDcghTRUFCMkJSOQozCMGsARIDMTA1GMEzIILNASjstqQDMLm4pAM4U0ABWAFqB0NMQVNTSUNyCFNFQUIyQlI5CmkKMwjBrAESAzEwNBiCzQEgwTMo0v6kAzCpgKUDOFNAAFgBagdDTEFTU0lDcghTRUFCMkJSOQoyCMGsARICNTgYwTMg78QBKJ-FpQMwkoalAzhTQAFYAWoHQ0xBU1NJQ3IIU0VBQjJCUjkSCggBEAEYASoCQVYYASIECAEQASgCKAMoBDAB) Thu, Feb 4 - Thu, Feb 11 · PTY · CUZ · Roundtrip [Select Avianca flight, departing Thu, Apr 1 from Panama City to Cusco, returning Wed, Apr 7, priced at $605 Found 3 days ago](https://www.expedia.com/Flights-Search?leg1=from:PTY,to:CUZ,departure:4/1/2027TANYT&leg2=from:CUZ,to:PTY,departure:4/7/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:604.01&airProductToken=AQplCjAIwawBEgI1NxjvxAEgwTMon6apAzD-pqkDOFBAAFgBagVMSUdIVHIIUEVBQjFCUkIKMQjBrAESAzEwNRjBMyCCzQEo7KypAzC0rqkDOFBAAVgBagVMSUdIVHIIUEVBQjFCUkIKZQoxCMGsARIDMTA0GILNASDBMyiy6akDMP%5FqqQM4UEAAWAFqBUxJR0hUcghQRUFCMUJSQgowCMGsARICNjAYwTMg78QBKOTzqQMwyPSpAzhQQAFYAWoFTElHSFRyCFBFQUIxQlJCEgwIARABGAEqAkFWMgAYASIECAEQASgCKAMoBDAB) Thu, Apr 1 - Wed, Apr 7 · PTY · CUZ · Roundtrip [Select Avianca flight, departing Thu, Apr 1 from Panama City to Cusco, returning Wed, Apr 7, priced at $609 Found 3 days ago](https://www.expedia.com/Flights-Search?leg1=from:PTY,to:CUZ,departure:4/1/2027TANYT&leg2=from:CUZ,to:PTY,departure:4/7/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:608.34&airProductToken=AQppCjIIwawBEgI1NxjvxAEgwTMon6apAzD-pqkDOFNAAFgBagdDTEFTU0lDcghTRUFCMkJSOQozCMGsARIDMTA1GMEzIILNASjsrKkDMLSuqQM4U0ABWAFqB0NMQVNTSUNyCFNFQUIyQlI5CmkKMwjBrAESAzEwNBiCzQEgwTMosumpAzD%5F6qkDOFNAAFgBagdDTEFTU0lDcghTRUFCMkJSOQoyCMGsARICNjAYwTMg78QBKOTzqQMwyPSpAzhTQAFYAWoHQ0xBU1NJQ3IIU0VBQjJCUjkSDAgBEAEYASoCQVYyABgBIgQIARABKAIoAygEMAE) Thu, Apr 1 - Wed, Apr 7 · PTY · CUZ · Roundtrip [Select Avianca flight, departing Mon, May 3 from Panama City to Cusco, returning Fri, May 7, priced at $610 Found 13 hours ago](https://www.expedia.com/Flights-Search?leg1=from:PTY,to:CUZ,departure:5/3/2027TANYT&leg2=from:CUZ,to:PTY,departure:5/7/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:609.88&airProductToken=AQplCjAIwawBEgI2MRjvxAEgwTMo-oysAzDZjawDOFBAAFgBagVMSUdIVHIIUEVBQjFCUkIKMQjBrAESAzEwNRjBMyCCzQEo7JSsAzC0lqwDOFBAAVgBagVMSUdIVHIIUEVBQjFCUkIKZQoxCMGsARIDMTA0GILNASDBMyjyuqwDML-8rAM4UEAAWAFqBUxJR0hUcghQRUFCMUJSQgowCMGsARICNTgYwTMg78QBKM7BrAMwt8KsAzhQQAFYAWoFTElHSFRyCFBFQUIxQlJCEgoIARABGAEqAkFWGAEiBAgBEAEoAigDKAQwAQ) Mon, May 3 - Fri, May 7 · PTY · CUZ · Roundtrip [Select Avianca flight, departing Mon, Aug 23 from Panama City to Cusco, returning Sat, Aug 28, priced at $615 Found 1 day ago](https://www.expedia.com/Flights-Search?leg1=from:PTY,to:CUZ,departure:8/23/2027TANYT&leg2=from:CUZ,to:PTY,departure:8/28/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:614.24&airProductToken=AQppCjIIwawBEgI1ORjvxAEgwTMozva1AzCo97UDOFNAAFgBagdDTEFTU0lDcghTRUFCMkJSOQozCMGsARIDMTA1GMEzIILNASjsgLYDMLSCtgM4U0ABWAFqB0NMQVNTSUNyCFNFQUIyQlI5CmkKMwjBrAESAzEwNBiCzQEgwTMokrK2AzDfs7YDOFNAAFgBagdDTEFTU0lDcghTRUFCMkJSOQoyCMGsARICNTYYwTMg78QBKJ-7tgMwg7y2AzhTQAFYAWoHQ0xBU1NJQ3IIU0VBQjJCUjkSCggBEAEYASoCQVYYASIECAEQASgCKAMoBDAB) Mon, Aug 23 - Sat, Aug 28 · PTY · CUZ · Roundtrip [Select Avianca flight, departing Wed, Jun 9 from Panama City to Cusco, returning Tue, Jun 15, priced at $630 Found 2 days ago](https://www.expedia.com/Flights-Search?leg1=from:PTY,to:CUZ,departure:6/9/2027TANYT&leg2=from:CUZ,to:PTY,departure:6/15/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:629.22&airProductToken=AQplCjAIwawBEgI1ORjvxAEgwTMo7qqvAzDIq68DOE9AAFgBagVMSUdIVHIIT0VBQjFCUkIKMQjBrAESAzEwNRjBMyCCzQEojLWvAzDUtq8DOE9AAVgBagVMSUdIVHIIT0VBQjFCUkIKZQoxCMGsARIDMTA0GILNASDBMyjS8a8DMJ%5FzrwM4UEAAWAFqBUxJR0hUcghQRUFCMUJSQgowCMGsARICNDAYwTMg78QBKKb0rwMwj%5FWvAzhQQAFYAWoFTElHSFRyCFBFQUIxQlJCEgoIARABGAEqAkFWGAEiBAgBEAEoAigDKAQwAQ) Wed, Jun 9 - Tue, Jun 15 · PTY · CUZ · Roundtrip [Select Avianca flight, departing Mon, May 3 from Panama City to Cusco, returning Fri, May 7, priced at $649 Found 6 days ago](https://www.expedia.com/Flights-Search?leg1=from:PTY,to:CUZ,departure:5/3/2027TANYT&leg2=from:CUZ,to:PTY,departure:5/7/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:648.10&airProductToken=AQplCjAIwawBEgI1ORjvxAEgwTMozoqsAzCoi6wDOFBAAFgBagVMSUdIVHIIUEVBQjFCUkIKMQjBrAESAzEwNRjBMyCCzQEo7JSsAzC0lqwDOFBAAVgBagVMSUdIVHIIUEVBQjFCUkIKZQoxCMGsARIDMTA0GILNASDBMyjyuqwDML-8rAM4T0AAWAFqBUxJR0hUcghPRUFCMUJSQgowCMGsARICNDAYwTMg78QBKMa9rAMwr76sAzhPQAFYAWoFTElHSFRyCE9FQUIxQlJCEgoIARABGAEqAkFWGAEiBAgBEAEoAigDKAQwAQ) Mon, May 3 - Fri, May 7 · PTY · Panam · a City · CUZ · Roundtrip [Select Avianca flight, departing Wed, Dec 9 from Panama City to Cusco, returning Sun, Dec 13, priced at $682 Found 23 hours ago](https://www.expedia.com/Flights-Search?leg1=from:PTY,to:CUZ,departure:12/9/2026TANYT&leg2=from:CUZ,to:PTY,departure:12/13/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:681.62&airProductToken=AQplCjAIwawBEgI1NxjvxAEgwTMojq-fAzDyr58DOFBAAFgBagVMSUdIVHIIUEVBQjFCUkIKMQjBrAESAzEwNRjBMyCCzQEozLWfAzCZt58DOFBAAVgBagVMSUdIVHIIUEVBQjFCUkIKZQoxCMGsARIDMTA0GILNASDBMyjS258DMKndnwM4TEAAWAFqBUxJR0hUcghMRUFCMUJSQgowCMGsARICNTYYwTMg78QBKJHlnwMw%5F-WfAzhMQAFYAWoFTElHSFRyCExFQUIxQlJCEgoIARABGAEqAkFWGAEiBAgBEAEoAigDKAQwAQ) Wed, Dec 9 - Sun, Dec 13 · PTY · CUZ · Roundtrip [Select Avianca flight, departing Sun, Jan 31 from Panama City to Cusco, returning Thu, Feb 4, priced at $685 Found 1 day ago](https://www.expedia.com/Flights-Search?leg1=from:PTY,to:CUZ,departure:1/31/2027TANYT&leg2=from:CUZ,to:PTY,departure:2/4/2027TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&flp=mdl:flights-flex-module,price:684.82&airProductToken=AQppCjIIwawBEgI2MRjvxAEgwTMotoKkAzCag6QDOFNAAFgBagdDTEFTU0lDcghTRUFCMkJSOQozCMGsARIDMTA1GMEzIILNASjsiaQDMLmLpAM4U0ABWAFqB0NMQVNTSUNyCFNFQUIyQlI5CmkKMwjBrAESAzEwNBiCzQEgwTMo8q-kAzDJsaQDOFBAAFgBagdDTEFTU0lDcghQRUFCMkJSQgoyCMGsARICNTgYwTMg78QBKL-2pAMwsrekAzhQQAFYAWoHQ0xBU1NJQ3IIUEVBQjJCUkISCggBEAEYASoCQVYYASIECAEQASgCKAMoBDAB) Sun, Jan 31 - Thu, Feb 4 · PTY · CUZ · Roundtrip ## Book with confidence ### Panama City to Cusco Flights #### The cheapest times to fly from Panama City to Cusco On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Cusco are during the month of February. You can find some of the cheapest flights from Panama City to Cusco with Expedia's search tool and vast selection of airlines. #### The best time to book a flight from Panama City to Cusco Sunday is one of the best days to book for cheap flights from Panama City to Cusco: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance. #### How to find cheap round-trip tickets from Panama City to Cusco Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Cusco in 2026\. You can also book with separate airlines for your outbound and return journeys, from $486 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference\*. This is available for a small fee, and is free to One Key Gold and Platinum tier members. Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Cusco flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps. You could also save big by booking one of Expedia's [vacation packages](https://www.expedia.com/package-deals). Bundling together your Panama City to Cusco airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures. *\*Terms apply.* *Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023\. The percentages you see are averages.* ## Frequently Asked Questions ### How much does a flight from Panama City (PTY-Tocumen Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) cost? You can find cheap one-way flights from $486 and cheap return flights $587 Panama City (PTY-Tocumen Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) with Expedia. One-way flights usually range from $293 to $1342, and return flights typically cost between $536 and $1826\. Flight prices vary based on the month and day of the week you want to travel, as well as the airline and how far in advance you book your ticket. Filter your search on Expedia by "Price (lowest to highest)" to see the cheapest fares first, and use the Price Tracking tool to receive alerts when Panama City (PTY-Tocumen Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) ticket fares go up or down. *\*Typical price ranges based on flights available on Expedia in the last year. Prices include multi-airline options.* ### What is the cheapest month to fly from Panama City (PTY-Tocumen Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)? The cheapest month to fly from PTY to CUZ is February when demand is low. Traveling in off-peak or shoulder months is usually a good way to secure cheap tickets, just remember to avoid flying during holidays if you're able to. Use the calendar view in your search to see which months have low fares on this route. ### Which airlines fly direct from Panama City (PTY-Tocumen Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)? Enter PTY to CUZ and your travel dates, then apply the 'Nonstop' filter to see only direct flights. ### What is the cheapest airline that flies from Panama City (PTY-Tocumen Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)? Avianca is one of the cheapest airlines offering connecting flights from Panama City (PTY) to Cusco (CUZ), with round-trip tickets starting from around $536\. Use Expedia's search tool to compare the prices and schedules of airlines that fly this route to find the best option for your plans and budget. *\*Prices based on flights available on Expedia in the last year.* ### How do I find cheap flights from Panama City (PTY-Tocumen Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)? To find a cheap flight from Panama City (PTY-Tocumen Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up [Price Tracking](https://www.expedia.com/why/price-tracking) and receive alerts when fares go up or down. ### What is the best time to fly from Panama City (PTY-Tocumen Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)? The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience. ### What is the earliest flight from Panama City (PTY-Tocumen Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)? The earliest flight from Tocumen International Airport (PTY) to Alejandro Velasco Astete International Airport (CUZ) typically departs at around 2:55 AM, operated by Avianca. This service is seasonal and active in January, October, and December, allowing you to start your journey early and make the most of your time in Cusco. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search. ### What are the most popular departure times for flights from Panama City (PTY-Tocumen Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)? The most popular departure times for flights from Tocumen International Airport (PTY) in Panama City to Alejandro Velasco Astete International Airport (CUZ) in Cusco are in the early morning, from midnight to 3am. About 42% of passengers prefer this time window. Avianca is a major carrier that offers flights during this time. This timing works well because it allows you to arrive in Cusco early and start your adventures right away. ### How long does it take to fly from Panama City (PTY-Tocumen Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)? A flight from PTY to CUZ with a layover takes around 17 hours 30 minutes, with the route covering approximately 1,643 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic. ### Can you fly business or first class from Panama City (PTY-Tocumen Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)? Business class seats are offered on the PTY to CUZ route with Avianca. ### How do I earn miles on a Panama City (PTY-Tocumen Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) flight with Expedia? It's easy to earn miles on a Panama City (PTY-Tocumen Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of [One Key™](https://www.expedia.com/welcome-one-key), you can also earn OneKeyCash™\* on top of your airline miles when you book with Expedia. \*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands. ### What airports do you fly into for Cusco from Tocumen Intl. (PTY)? From Tocumen Intl. (PTY), you can fly into Alejandro Velasco Astete Intl. (CUZ) to reach Cusco. Compare routes and airports on Expedia to find the best flight options for your travel plans. ### Is it cheaper to buy a plane ticket from Panama City (PTY-Tocumen Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) at the last minute? Typically, booking a last minute flight from Panama City (PTY-Tocumen Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare. ### Is it cheaper to book a Panama City (PTY-Tocumen Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) flight and hotel package? Securing a Panama City (PTY-Tocumen Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) [Cusco Vacation Packages](https://www.expedia.com/cusco.d941.destination-travel-guides) is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars. ### Can I cancel or change the date of my flight from Panama City (PTY-Tocumen Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.)? If you booked your Panama City (PTY-Tocumen Intl.) to Cusco (CUZ-Alejandro Velasco Astete Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in [your itinerary](https://www.expedia.com/trips) or confirmation email. Or, head to our [Customer Service portal](https://www.expedia.com/helpcenter/) if you'd like more information. ## Travel information | Origin airport | Tocumen Intl. Airport | | ------------------- | -------------------------------------- | | Destination airport | Alejandro Velasco Astete Intl. Airport | | Distance | 1,643 miles away | | Airlines serving | Avianca | | Popular airline | Avianca | | Roundtrip price | $587 | ## Explore a world of travel with Expedia - [Flights](?equalTargetTab=tab-0) - [Flights from Memphis (MEM) to Cusco (CUZ)](https://www.expedia.com/lp/flights/mem/cuz/memphis-to-cusco) - [Flights from Newark Liberty Intl. 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[Flights from Juliaca (JUL) to Cusco (CUZ)](https://www.expedia.com/lp/flights/jul/cuz/juliaca-to-cusco) - [Flights from Cleveland (CLE) to Cusco (CUZ)](https://www.expedia.com/lp/flights/cle/cuz/cleveland-to-cusco) - [Flights from Raleigh (RDU) to Cusco (CUZ)](https://www.expedia.com/lp/flights/rdu/cuz/raleigh-to-cusco) - [Flights from Omaha (OMA) to Cusco (CUZ)](https://www.expedia.com/lp/flights/oma/cuz/omaha-to-cusco) - [Flights from Fort Lauderdale (FLL) to Cusco (CUZ)](https://www.expedia.com/lp/flights/fll/cuz/fort-lauderdale-to-cusco) - [Flights from Reno (RNO) to Cusco (CUZ)](https://www.expedia.com/lp/flights/rno/cuz/reno-to-cusco) - [Flights from Detroit (DTW) to Cusco (CUZ)](https://www.expedia.com/lp/flights/dtw/cuz/detroit-to-cusco) - [Flights from Austin (AUS) to Cusco (CUZ)](https://www.expedia.com/lp/flights/aus/cuz/austin-to-cusco) - [Flights from Houston (HOU) to Cusco (CUZ)](https://www.expedia.com/lp/flights/hou/cuz/houston-to-cusco) - [Flights from Arequipa (AQP) to Cusco (CUZ)](https://www.expedia.com/lp/flights/aqp/cuz/arequipa-to-cusco) - [Flights from St. Louis (STL) to Cusco (CUZ)](https://www.expedia.com/lp/flights/stl/cuz/st-louis-to-cusco) - [Flights from Orlando (MCO) to Cusco (CUZ)](https://www.expedia.com/lp/flights/mco/cuz/orlando-to-cusco) - [Flights from Rio de Janeiro (GIG) to Cusco (CUZ)](https://www.expedia.com/lp/flights/gig/cuz/rio-de-janeiro-to-cusco) - [Flights from Hartford (BDL) to Cusco (CUZ)](https://www.expedia.com/lp/flights/bdl/cuz/hartford-to-cusco) - [Flights from Indianapolis (IND) to Cusco (CUZ)](https://www.expedia.com/lp/flights/ind/cuz/indianapolis-to-cusco) - [Flights from Portland (PDX) to Cusco (CUZ)](https://www.expedia.com/lp/flights/pdx/cuz/portland-to-cusco) - [Flights from Montevideo (MVD) to Cusco (CUZ)](https://www.expedia.com/lp/flights/mvd/cuz/montevideo-to-cusco) - [Flights from Chicago (ORD) to Cusco (CUZ)](https://www.expedia.com/lp/flights/ord/cuz/chicago-to-cusco) - [Flights from Buffalo (BUF) to Cusco (CUZ)](https://www.expedia.com/lp/flights/buf/cuz/buffalo-to-cusco) - [Flights from São Paulo (GRU) to Cusco (CUZ)](https://www.expedia.com/lp/flights/gru/cuz/sao-paulo-to-cusco) - [Flights from Miami (MIA) to Cusco (CUZ)](https://www.expedia.com/lp/flights/mia/cuz/miami-to-cusco) - [Flights from Cartagena (CTG) to Cusco (CUZ)](https://www.expedia.com/lp/flights/ctg/cuz/cartagena-to-cusco) - [Flights from Spokane (GEG) to Cusco (CUZ)](https://www.expedia.com/lp/flights/geg/cuz/spokane-to-cusco) - [Flights from Philadelphia (PHL) to Cusco (CUZ)](https://www.expedia.com/lp/flights/phl/cuz/philadelphia-to-cusco) - [Flights from Albuquerque (ABQ) to Cusco (CUZ)](https://www.expedia.com/lp/flights/abq/cuz/albuquerque-to-cusco) - [Flights from Charlotte (CLT) to Cusco (CUZ)](https://www.expedia.com/lp/flights/clt/cuz/charlotte-to-cusco) - [Flights from La Paz (LPB) to Cusco (CUZ)](https://www.expedia.com/lp/flights/lpb/cuz/la-paz-to-cusco) - [Flights from Cancun (CUN) to Cusco (CUZ)](https://www.expedia.com/lp/flights/cun/cuz/cancun-to-cusco) - [Flights from New York (NYC) to Cusco (CUZ)](https://www.expedia.com/lp/flights/nyc/cuz/new-york-to-cusco) - [Flights from Honolulu (HNL) to Cusco (CUZ)](https://www.expedia.com/lp/flights/hnl/cuz/honolulu-to-cusco) - [Flights from Las Vegas (LAS) to Cusco (CUZ)](https://www.expedia.com/lp/flights/las/cuz/las-vegas-to-cusco) - [Flights from Pisco (PIO) to Cusco (CUZ)](https://www.expedia.com/lp/flights/pio/cuz/pisco-to-cusco) - [Flights from Uyuni (UYU) to Cusco (CUZ)](https://www.expedia.com/lp/flights/uyu/cuz/uyuni-to-cusco) - [Flights from Tumbes (TBP) to Cusco (CUZ)](https://www.expedia.com/lp/flights/tbp/cuz/tumbes-to-cusco) - [Flights from Louisville (SDF) to Cusco (CUZ)](https://www.expedia.com/lp/flights/sdf/cuz/louisville-to-cusco) - [Flights from Mendoza (MDZ) to Cusco (CUZ)](https://www.expedia.com/lp/flights/mdz/cuz/mendoza-to-cusco) - [Flights from San Antonio (SAT) to Cusco (CUZ)](https://www.expedia.com/lp/flights/sat/cuz/san-antonio-to-cusco) - [Flights from Reykjavik (KEF) to Cusco (CUZ)](https://www.expedia.com/lp/flights/kef/cuz/reykjavik-to-cusco) - [Flights from Seattle (SEA) to Cusco (CUZ)](https://www.expedia.com/lp/flights/sea/cuz/seattle-to-cusco) - [Flights from Kansas City (MCI) to Cusco (CUZ)](https://www.expedia.com/lp/flights/mci/cuz/kansas-city-to-cusco) - [Flights from Columbus (CMH) to Cusco (CUZ)](https://www.expedia.com/lp/flights/cmh/cuz/columbus-to-cusco) - [Flights from Tampa (TPA) to Cusco (CUZ)](https://www.expedia.com/lp/flights/tpa/cuz/tampa-to-cusco) - [Flights from Brasilia (BSB) to Cusco (CUZ)](https://www.expedia.com/lp/flights/bsb/cuz/brasilia-to-cusco) - [Flights from Vancouver (YVR) to Cusco (CUZ)](https://www.expedia.com/lp/flights/yvr/cuz/vancouver-to-cusco) - [Flights from New York (JFK) to Cusco (CUZ)](https://www.expedia.com/lp/flights/jfk/cuz/new-york-to-cusco) - [Flights from Tacna (TCQ) to Cusco (CUZ)](https://www.expedia.com/lp/flights/tcq/cuz/tacna-to-cusco) - [Flights from San José (SJO) to Cusco (CUZ)](https://www.expedia.com/lp/flights/sjo/cuz/san-jose-to-cusco) - [Flights from Medellín (MDE) to Cusco (CUZ)](https://www.expedia.com/lp/flights/mde/cuz/medellin-to-cusco) - [Flights from San Juan (SJU) to Cusco (CUZ)](https://www.expedia.com/lp/flights/sju/cuz/san-juan-to-cusco) - [Flights from Sacramento (SMF) to Cusco (CUZ)](https://www.expedia.com/lp/flights/smf/cuz/sacramento-to-cusco) - [Flights from Pittsburgh (PIT) to Cusco (CUZ)](https://www.expedia.com/lp/flights/pit/cuz/pittsburgh-to-cusco) - [Flights from Cincinnati (CVG) to Cusco (CUZ)](https://www.expedia.com/lp/flights/cvg/cuz/cincinnati-to-cusco) - [Flights from Phoenix (PHX) to Cusco (CUZ)](https://www.expedia.com/lp/flights/phx/cuz/phoenix-to-cusco) - [Flights from Montreal (YUL) to Cusco (CUZ)](https://www.expedia.com/lp/flights/yul/cuz/montreal-to-cusco) - [Flights from Minneapolis (MSP) to Cusco (CUZ)](https://www.expedia.com/lp/flights/msp/cuz/minneapolis-to-cusco) - [Flights from Guatemala City (GUA) to Cusco (CUZ)](https://www.expedia.com/lp/flights/gua/cuz/guatemala-city-to-cusco) - [Flights from Quito (UIO) to Cusco (CUZ)](https://www.expedia.com/lp/flights/uio/cuz/quito-to-cusco) - [Flights from Asheville (AVL) to Cusco (CUZ)](https://www.expedia.com/lp/flights/avl/cuz/asheville-to-cusco) - [Flights from Washington (DCA) to Cusco (CUZ)](https://www.expedia.com/lp/flights/dca/cuz/washington-to-cusco) - [Flights from Tijuana (TIJ) to Cusco (CUZ)](https://www.expedia.com/lp/flights/tij/cuz/tijuana-to-cusco) - [Flights from Grand Rapids (GRR) to Cusco (CUZ)](https://www.expedia.com/lp/flights/grr/cuz/grand-rapids-to-cusco) - [Flights from Calgary (YYC) to Cusco (CUZ)](https://www.expedia.com/lp/flights/yyc/cuz/calgary-to-cusco) - [Flights from Puerto Maldonado (PEM) to Cusco (CUZ)](https://www.expedia.com/lp/flights/pem/cuz/puerto-maldonado-to-cusco) - [Flights from Santa Cruz (VVI) to Cusco (CUZ)](https://www.expedia.com/lp/flights/vvi/cuz/santa-cruz-to-cusco) - [Flights from San Diego (SAN) to Cusco (CUZ)](https://www.expedia.com/lp/flights/san/cuz/san-diego-to-cusco) - [Flights from Iguassu Falls (IGU) to Cusco (CUZ)](https://www.expedia.com/lp/flights/igu/cuz/iguassu-falls-to-cusco) - [Flights from Cuenca (CUE) to Cusco (CUZ)](https://www.expedia.com/lp/flights/cue/cuz/cuenca-to-cusco) - [Flights from Huaraz (ATA) to Cusco (CUZ)](https://www.expedia.com/lp/flights/ata/cuz/huaraz-to-cusco) - [Flights from Chicago (MDW) to Cusco (CUZ)](https://www.expedia.com/lp/flights/mdw/cuz/chicago-to-cusco) - [Flights from Greenville (GSP) to Cusco (CUZ)](https://www.expedia.com/lp/flights/gsp/cuz/greenville-to-cusco) - [Flights from Nashville (BNA) to Cusco (CUZ)](https://www.expedia.com/lp/flights/bna/cuz/nashville-to-cusco) - [Flights from Iquitos (IQT) to Cusco (CUZ)](https://www.expedia.com/lp/flights/iqt/cuz/iquitos-to-cusco) - [Flights from Toronto (YYZ) to Cusco (CUZ)](https://www.expedia.com/lp/flights/yyz/cuz/toronto-to-cusco) - [Flights from Baltimore (BWI) to Cusco (CUZ)](https://www.expedia.com/lp/flights/bwi/cuz/baltimore-to-cusco) - [Flights from Washington (IAD) to Cusco (CUZ)](https://www.expedia.com/lp/flights/iad/cuz/washington-to-cusco) - [Flights from Atlanta (ATL) to Cusco (CUZ)](https://www.expedia.com/lp/flights/atl/cuz/atlanta-to-cusco) - [Flights from Jacksonville (JAX) to Cusco (CUZ)](https://www.expedia.com/lp/flights/jax/cuz/jacksonville-to-cusco) - [Flights from Buenos Aires (EZE) to Cusco (CUZ)](https://www.expedia.com/lp/flights/eze/cuz/buenos-aires-to-cusco) - [Flights from Tel Aviv (TLV) to Cusco (CUZ)](https://www.expedia.com/lp/flights/tlv/cuz/tel-aviv-to-cusco) - [Flights from San Francisco (SFO) to Cusco (CUZ)](https://www.expedia.com/lp/flights/sfo/cuz/san-francisco-to-cusco) - [Flights from San Salvador (SAL) to Cusco (CUZ)](https://www.expedia.com/lp/flights/sal/cuz/san-salvador-to-cusco) - [Flights from Dallas (DFW) to Cusco (CUZ)](https://www.expedia.com/lp/flights/dfw/cuz/dallas-to-cusco) - [Flights from Boise (BOI) to Cusco (CUZ)](https://www.expedia.com/lp/flights/boi/cuz/boise-to-cusco) - [Flights from New Orleans (MSY) to Cusco (CUZ)](https://www.expedia.com/lp/flights/msy/cuz/new-orleans-to-cusco) - [Flights from Mexico City (MEX) to Cusco (CUZ)](https://www.expedia.com/lp/flights/mex/cuz/mexico-city-to-cusco) - [Flights from Bogotá (BOG) to Cusco (CUZ)](https://www.expedia.com/lp/flights/bog/cuz/bogota-to-cusco) - [Flights from Guayaquil (GYE) to Cusco (CUZ)](https://www.expedia.com/lp/flights/gye/cuz/guayaquil-to-cusco) - [Flights from Los Angeles (LAX) to Cusco (CUZ)](https://www.expedia.com/lp/flights/lax/cuz/los-angeles-to-cusco) - [Flights from Manchester (MHT) to Cusco (CUZ)](https://www.expedia.com/lp/flights/mht/cuz/manchester-to-cusco) \*Available to One Key members. ## Other language versions ```yaml hreflang: x-default: https://www.expedia.com/lp/flights/pty/cuz/panama-city-to-cusco es-MX: https://www.expedia.mx/lp/vuelos/pty/cuz/panama-a-cusco en-TH: https://www.expedia.co.th/en/lp/flights/pty/cuz/panama-city-to-cusco nl-NL: https://www.expedia.nl/lp/vluchten/pty/cuz/panama-stad-naar-cusco en-US: https://www.expedia.com/lp/flights/pty/cuz/panama-city-to-cusco pt-BR: https://www.expedia.com.br/lp/voos/pty/cuz/cidade-do-panama-para-cusco en-GB: https://www.expedia.co.uk/lp/flights/pty/cuz/panama-city-to-cusco en-MY: https://www.expedia.com.my/lp/flights/pty/cuz/panama-city-to-cusco ar: https://www.expedia.sa/lp/flights/pty/cuz/panama-city-to-cusco fr-CA: https://www.expedia.ca/fr/lp/vols/pty/cuz/panama-a-cusco fr-BE: https://www.expedia.be/fr/lp/vols/pty/cuz/panama-a-cusco en-IN: https://www.expedia.co.in/lp/flights/pty/cuz/panama-city-to-cusco fr-FR: https://www.expedia.fr/lp/vols/pty/cuz/panama-a-cusco zh-hant-HK: https://www.expedia.com.hk/lp/flights/pty/cuz/panama-city-to-cusco en-PH: https://www.expedia.com.ph/lp/flights/pty/cuz/panama-city-to-cusco sv-SE: https://www.expedia.se/lp/flyg/pty/cuz/panama-city-till-cusco zh-hans-HK: https://www.expedia.com.hk/cn/lp/flights/pty/cuz/panama-city-to-cusco ja-JP: https://www.expedia.co.jp/lp/flights/pty/cuz/panama-city-to-cusco it-IT: https://www.expedia.it/lp/voli/pty/cuz/citta-di-panama-a-cusco nb-NO: https://www.expedia.no/lp/fly/pty/cuz/panama-by-til-cusco en-CA: https://www.expedia.ca/lp/flights/pty/cuz/panama-city-to-cusco th-TH: https://www.expedia.co.th/lp/flights/pty/cuz/panama-city-to-cusco de-AT: https://www.expedia.at/lp/fluge/pty/cuz/panama-stadt-nach-cusco en-NZ: https://www.expedia.co.nz/lp/flights/pty/cuz/panama-city-to-cusco en-AU: https://www.expedia.com.au/lp/flights/pty/cuz/panama-city-to-cusco da-DK: https://www.expedia.dk/lp/fly/pty/cuz/panama-city-til-cusco en-SG: https://www.expedia.com.sg/lp/flights/pty/cuz/panama-city-to-cusco es-ES: https://www.expedia.es/lp/vuelos/pty/cuz/panama-a-cusco es: https://www.expedia.com/es/lp/vuelos/pty/cuz/panama-a-cusco en-JP: https://www.expedia.co.jp/en/lp/flights/pty/cuz/panama-city-to-cusco de-DE: https://www.expedia.de/lp/fluge/pty/cuz/panama-stadt-nach-cusco ko-KR: https://www.expedia.co.kr/lp/flights/pty/cuz/panama-city-to-cusco de-CH: https://www.expedia.ch/lp/fluege/pty/cuz/panama-stadt-nach-cusco en-KR: https://www.expedia.co.kr/en/lp/flights/pty/cuz/panama-city-to-cusco ```