Popular airlines from Tocumen Intl. Airport (PTY) to Alejandro Velasco Astete Intl. Airport (CUZ)

Cheap Flights from Panama City to Cusco (PTY-CUZ)

Prices were available within the past 7 days and start at $299 for one-way flights and $530 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

avianca
Tue, Nov 4 - Wed, Nov 12
PTY
Panama City
CUZ
Cusco
$530 Roundtrip, found 5 hours ago
$530
Roundtrip
found 5 hours ago
Select avianca flight, departing Tue, Nov 4 from Panama City to Cusco, returning Wed, Nov 12, priced at $530 found 5 hours ago
avianca
Mon, Jan 19 - Mon, Jan 26
PTY
Panama City
CUZ
Cusco
$547 Roundtrip, found 14 hours ago
$547
Roundtrip
found 14 hours ago
Select avianca flight, departing Mon, Jan 19 from Panama City to Cusco, returning Mon, Jan 26, priced at $547 found 14 hours ago
avianca
Tue, Nov 4 - Mon, Nov 10
PTY
Panama City
CUZ
Cusco
$583 Roundtrip, found 5 hours ago
$583
Roundtrip
found 5 hours ago
Select avianca flight, departing Tue, Nov 4 from Panama City to Cusco, returning Mon, Nov 10, priced at $583 found 5 hours ago
avianca
Tue, Jul 7 - Wed, Jul 15
PTY
Panama City
CUZ
Cusco
$590 Roundtrip, found 6 hours ago
$590
Roundtrip
found 6 hours ago
Select avianca flight, departing Tue, Jul 7 from Panama City to Cusco, returning Wed, Jul 15, priced at $590 found 6 hours ago
avianca
Tue, Nov 4 - Fri, Nov 14
PTY
Panama City
CUZ
Cusco
$598 Roundtrip, found 5 hours ago
$598
Roundtrip
found 5 hours ago
Select avianca flight, departing Tue, Nov 4 from Panama City to Cusco, returning Fri, Nov 14, priced at $598 found 5 hours ago
avianca
Fri, Dec 5 - Mon, Dec 8
PTY
Panama City
CUZ
Cusco
$624 Roundtrip, found 1 day ago
$624
Roundtrip
found 1 day ago
Select avianca flight, departing Fri, Dec 5 from Panama City to Cusco, returning Mon, Dec 8, priced at $624 found 1 day ago
avianca
Sun, Nov 2 - Mon, Nov 10
PTY
Panama City
CUZ
Cusco
$637 Roundtrip, found 5 hours ago
$637
Roundtrip
found 5 hours ago
Select avianca flight, departing Sun, Nov 2 from Panama City to Cusco, returning Mon, Nov 10, priced at $637 found 5 hours ago
avianca
Wed, Nov 12 - Sun, Nov 16
PTY
Panama City
CUZ
Cusco
$642 Roundtrip, found 15 hours ago
$642
Roundtrip
found 15 hours ago
Select avianca flight, departing Wed, Nov 12 from Panama City to Cusco, returning Sun, Nov 16, priced at $642 found 15 hours ago
avianca
Sun, Nov 2 - Fri, Nov 14
PTY
Panama City
CUZ
Cusco
$652 Roundtrip, found 5 hours ago
$652
Roundtrip
found 5 hours ago
Select avianca flight, departing Sun, Nov 2 from Panama City to Cusco, returning Fri, Nov 14, priced at $652 found 5 hours ago
Copa
Fri, Mar 27 - Tue, Mar 31
PTY
Panama City
CUZ
Cusco
$759 Roundtrip, found 2 days ago
$759
Roundtrip
found 2 days ago
Select Copa flight, departing Fri, Mar 27 from Panama City to Cusco, returning Tue, Mar 31, priced at $759 found 2 days ago

Alternative airports near Cusco

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Alejandro Velasco Astete Intl. CUZ. Cheapest and Closest option available. Average driving time to city center is 4 minutes. Flights from $530
CUZ
Alejandro Velasco Astete Intl.
CheapestClosest
Average driving time to city center4 min
Flights from $530

Frequently asked questions

How much does a flight from Tocumen Intl. Airport (PTY) to Alejandro Velasco Astete Intl. Airport (CUZ) cost?
Lock in a cheap one-way flight from $299 or cheap return flight from $530 from Tocumen Intl. Airport (PTY) to Alejandro Velasco Astete Intl. Airport (CUZ) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight deals on this route.
What is the cheapest month to fly from Tocumen Intl. Airport (PTY) to Alejandro Velasco Astete Intl. Airport (CUZ)?
The cheapest month to fly from PTY to CUZ is November, when demand is low. Off-peak months are usually when you'll find lower airfares between these airports.
What is the cheapest airline that flies from Tocumen Intl. Airport (PTY) to Alejandro Velasco Astete Intl. Airport (CUZ)?
Use the filter tool on Expedia to compare different airlines and find the cheapest carrier that'll fly you from PTY to CUZ. Then, sort your results by "Price (lowest to highest)" to snag a good deal.
How many flights per day from Tocumen Intl. Airport (PTY) to Alejandro Velasco Astete Intl. Airport (CUZ)?
There aren't any daily nonstop flights departing from Tocumen Intl. Airport (PTY) to Alejandro Velasco Astete Intl. Airport (CUZ). But you can book flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be cruising above the clouds in no time at all.
What day of the week has the most flights from PTY to CUZ?
You'll usually find Tuesday the quietest day for flights, while Fridays are often the busiest.* However this can vary from season to season and during peak travel times or public holidays.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Tocumen Intl. Airport (PTY) to Alejandro Velasco Astete Intl. Airport (CUZ)?
Opt for a flight from Tocumen Intl. Airport (PTY) to Alejandro Velasco Astete Intl. Airport (CUZ) that takes off before 3 PM to reduce the risk of cancellations and delays. Departures later than this have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Tocumen Intl. Airport (PTY) to Alejandro Velasco Astete Intl. Airport (CUZ) last-minute?
Holding off until just before your trip to book a flight from PTY to CUZ often results in higher prices. Although you may find some last-minute offers, they're not always guaranteed. Keep your travel plans flexible for a better chance of getting a bargain.
Is it cheaper to book a PTY to CUZ flight and hotel package?
You'll typically save money by booking a PTY to CUZ flight and hotel package compared to booking separately. In fact, you could save hundreds of dollars by bundling with Expedia. And it's simple to manage everything in one convenient place. Once you've selected your ideal flights and accommodations, consider adding extras like tours, car rentals and activities.
Can I cancel or change the date of my flight from Tocumen Intl. Airport (PTY) to Alejandro Velasco Astete Intl. Airport (CUZ)?
Usually, it's possible to cancel or reschedule your PTY to CUZ flight. However, for bookings made more than 24 hours ago, additional charges may apply. Refer to your airline's policies in your itinerary to see what changes are allowed and whether any costs are involved. You'll also find more details on our Customer Service portal.

Book with confidence

Panama City to Cusco Flights

The cheapest times to fly from Panama City to Cusco

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Panama City to Cusco are during the month of November. You can find some of the cheapest flights from Panama City to Cusco with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Panama City to Cusco

Sunday is one of the best days to book for cheap flights from Panama City to Cusco: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Panama City to Cusco

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Panama City to Cusco in 2025. You can also book with separate airlines for your outbound and return journeys, from $299 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Panama City to Cusco flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Panama City to Cusco airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Panama City to Cusco Flights

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*Available to One Key members.