$116 Cheap American Airlines flights Denver (DEN) to Key West (EYW)

Make use of the "Price (lowest to highest)" filter on Expedia to look for cheap American Airlines return flights from $231 from DEN to EYW. Affordable one-way tickets from $116 are also on offer.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for cheap American Airlines flights from Denver Intl. Airport (DEN) to Key West Intl. Airport (EYW) one to three months prior to your departure date. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare type and journey, the best day to book a domestic flight is usually Sunday and the most expensive day tends to be Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Browse American Airlines's earliest flights from DEN to EYW by checking the "Early Morning" and "Morning" filters. Not only will you arrive at your destination sooner, early departures are also 20% less likely to be canceled.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.