$185 Cheap American Airlines flights Des Moines (DSM) to Puerto Vallarta (PVR)

Scoring cheap one-way American Airlines flights from DSM to PVR from $185 on Expedia couldn't be simpler — just filter by "Price (lowest to highest)." Or check out our affordable round-trip fares from $421 for your next getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

To discover affordable flights from DSM to PVR with American Airlines, start searching about one month before your intended departure. You can save 17% when you lock in your international tickets 18 to 29 days ahead instead of booking four to five months in advance. Another helpful tip? Booking on Sunday offers average savings of 17% compared to Friday (the most expensive day).**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Search American Airlines's earliest flights from DSM to PVR by using our "Morning" and "Early Morning" filters. Not only will you get to where you're going sooner, early departures also have a 20% less chance of being canceled.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.