$163 Cheap American Airlines flights Des Moines (DSM) to Miami (MIA)

Set the "Price (lowest to highest)" filter on Expedia to search for cheap American Airlines round-trip flights from $208 from DSM to MIA. Affordable one-way fares from $163 are available too.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

For cheap American Airlines fares from Des Moines Intl. Airport (DSM) to Miami Intl. Airport (MIA), start searching one to three months before your planned departure. Reserving domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also impact what you pay. Sunday tends to be the cheapest, while Monday is often the most expensive for domestic flights. You can save 6% on average by choosing to book on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

The first American Airlines flight from DSM to MIA departs at 6:46AM UTC-6, arriving at 11:08AM UTC-5. If you'd like to set off later in the day, the last American Airlines flight leaves DSM at 6:46AM UTC-6 and touches down at MIA at 11:08AM UTC-5. Flying before noon is often a good idea as morning and mid-morning flights are least likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.