$225 Cheap American Airlines flights Syracuse (SYR) to Columbia (CAE)

Make use of the “Price (lowest to highest)” filter on Expedia to find cheap American Airlines return flights from $279 from SYR to CAE. Affordable one-way options from $225 are also on offer.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Browse for one-way or return flights to Columbia in January or December. You could find cheaper fares with American Airlines during these off-peak times.

Begin your search one to three months before your departure to score cheap fares on American Airlines flights from Hancock Intl. Airport (SYR) to Columbia Metropolitan Airport (CAE). You can save 25% by booking your domestic flight 34 to 86 days in advance compared to last-minute reservations made 6 to 12 days out. You could also cut costs by buying your fare on a Sunday, as it’s 6% cheaper on average than a Monday, the most expensive day to book.* Get your timing right, and you can enjoy significant savings on domestic journeys.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Select our “Nonstop” filter when searching for direct American Airlines flights from SYR to CAE. You can also compare other airlines offering the same nonstop journey.

Search American Airlines’s earliest flights from SYR to CAE by selecting our “Morning” and “Early Morning” filters. Not only will you arrive at your destination sooner, early departures also experience 20% fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Columbia Metropolitan Airport (CAE) is the main Columbia gateway for American Airlines flights from Hancock Intl. Airport (SYR).

Depending on the type of fare you purchased, a fee generally applies if you cancel or reschedule your flight more than 24 hours after it’s been confirmed. To find tickets with more flexibility, select our “No cancel fee” or “Changes included” filter while searching for flights. For more information on changing or canceling your reservation, head to “Trips,” select your flight and tick “Manage Booking.”