$126 Cheap American Airlines flights Key West (EYW) to Los Angeles (LAX)

Set the “Price (lowest to highest)” filter on Expedia to look for cheap American Airlines round-trip flights from $251 from EYW to LAX. Affordable one-way tickets from $126 are available as well.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

January is one of the cheapest months to jet away to Los Angeles with American Airlines. You could also find excellent prices on one-way and round-trip tickets in February.

Search for affordable American Airlines flights from Key West Intl. Airport (EYW) to Los Angeles Intl. Airport (LAX) one to three months prior to your departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare class and itinerary, the best day of the week to book a domestic flight is usually Sunday and the most expensive day tends to be Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Select our “Nonstop” filter when searching for direct American Airlines flights from EYW to LAX. It’s also a great way to compare other airlines servicing the same direct trip.

Find American Airlines’s earliest flights from EYW to LAX by selecting our “Morning” and “Early Morning” filters. Not only will you get to where you’re going sooner, early departures also experience 20% fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

Los Angeles Intl. Airport (LAX) is the main Los Angeles hub for American Airlines flights from Key West Intl. Airport (EYW).

Depending on your ticket type, a fee generally applies if you cancel or reschedule your booking more than 24 hours after it has been confirmed. To secure flexible plane tickets, select our “Changes included” or “No cancel fee” filter while searching for flights. To learn more about canceling or changing your reservation, head to “Trips,” select your flight and tick “Manage Booking.”