$100 Cheap American Airlines flights St. Louis (STL) to Sioux Falls (FSD)

Make use of the "Price (lowest to highest)" filter on Expedia to look for cheap American Airlines return flights from $229 from STL to FSD. Affordable one-way tickets from $100 are also on offer.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Begin your search one to three months ahead of your travel date to score cheap fares on American Airlines flights from Lambert-St. Louis Intl. Airport (STL) to Sioux Falls Regional Airport (FSD). You can save 25% by booking your domestic flight 34 to 86 days in advance compared to last-minute reservations made 6 to 12 days out. You could also reduce costs by buying your fare on a Sunday, as it's 6% cheaper on average than a Monday, the most expensive day to book.* Get the timing right, and you can enjoy significant savings on domestic journeys.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Sort your results by "Early Morning" and "Morning" to see the earliest departures from STL to FSD. Jetting off early means you're less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.