$170 Cheap American Airlines flights Knoxville (TYS) to Dallas (DFW)

Landing cheap one-way American Airlines flights from TYS to DFW from $170 on Expedia couldn't be easier — just filter by "Price (lowest to highest)." Or check out our affordable round-trip fares from $306 for your next getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for affordable American Airlines flights from McGhee Tyson Airport (TYS) to Dallas-Fort Worth Intl. Airport (DFW) one to three months before your departure date. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare type and journey, the ideal day to book a domestic flight is generally Sunday and the most expensive tends to be Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Setting off from TYS at 5:23AM UTC-5, the first American Airlines flight to DFW arrives at 7:08AM UTC-6. Flying earlier in the day means you're less likely to encounter cancellations or delays.* After something later? The last American Airlines flight from TYS to DFW departs at 6:37PM UTC-5 and touches down at 8:07PM UTC-6.*Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.