$159 Cheap American Airlines flights Knoxville (TYS) to Miami (MIA)

Use the "Price (lowest to highest)" filter on Expedia to find cheap American Airlines return flights from $159 from TYS to MIA. Affordable one-way tickets from $159 are available too.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Search for cheap American Airlines flights from McGhee Tyson Airport (TYS) to Miami Intl. Airport (MIA) one to three months prior to your departure day. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare class and journey, the ideal day to book a domestic flight is usually Sunday and the most expensive tends to be Monday. Passengers who book on a Sunday can save 6% on average compared to those who book their travel on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

The first flight from TYS to MIA with American Airlines departs at 5:52AM UTC-5. You'll touch down at 8:04AM UTC-5. The final American Airlines flight of the day takes off at 6:20AM UTC-5 and arrives at 8:32AM UTC-5. With 20% fewer cancellations for morning departures, heading out early is typically the best choice.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.