$143 Cheap American Airlines flights Missoula (MSO) to Chicago (ORD)

Finding cheap one-way American Airlines flights from MSO to ORD from $143 on Expedia is easy — just filter by “Price (lowest to highest).” Or check out our affordable round-trip fares from $235 for your next break.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

January is one of the most affordable months to get away to Chicago with American Airlines. You could also find great prices on one-way and round-trip tickets in February.

Look for affordable American Airlines flights from Missoula Intl. Airport (MSO) to O’Hare Intl. Airport (ORD) one to three months prior to your day of departure. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. Regardless of fare class and journey, the best day to book a domestic flight is generally Sunday and the most expensive tends to be Monday. Passengers who book on a Sunday can save 6% on average compared to those who book their travel on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Simply enter your dates, click search and tick the “Nonstop” filter on Expedia to find any direct flights from MSO to ORD with American Airlines or other carriers.

Search American Airlines’s earliest flights from MSO to ORD by selecting our “Early Morning” and “Morning” filters. Not only will you get to where you’re going sooner, early departures are also 20% less likely to be canceled.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

American Airlines flights from Missoula Intl. Airport (MSO) to Chicago arrive at O’Hare Intl. Airport (ORD). This is the main entry point to this destination.

In most cases, you can modify or cancel your flight, although there may be a charge if you made your booking over 24 hours ago. Need flexible options? Make use of our “No cancel fee” or “Changes included” filter to find flights that won’t charge you extra if you have to revise your plans. To make modifications, go to “Trips,” select your flight and click on “Manage Booking” for further information.