Cheap American Airlines flights Myrtle Beach (MYR) to Islip (ISP)

You’ll discover cheap round-trip American Airlines flights from MYR to ISP by organizing your results from “Price (lowest to highest)” on Expedia. Or look for options for a one-way trip.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Browse for round-trip or one-way flights to Islip in January or February. You could find lower fares with American Airlines during these off-season months.

Begin your search one to three months ahead of your departure date to get cheap fares on American Airlines flights from Myrtle Beach Intl. Airport (MYR) to MacArthur Airport (ISP). You can save 25% by booking your domestic flight 34 to 86 days in advance versus last-minute reservations made 6 to 12 days out. You could also reduce costs by buying your fare on a Sunday, as it’s 6% cheaper on average than a Monday, the most expensive day to book.* Get the timing right, and you can enjoy significant savings on domestic journeys.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC’s global airline sales database.

Enter your dates, hit search and check “Nonstop” on Expedia to browse any direct flights from MYR to ISP with American Airlines or another carrier.

To find the earliest departure from MYR to ISP with American Airlines, filter your results by “Morning” and “Early Morning.” Choosing an early flight generally means you’ll experience fewer cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG’s global flight data platform.

American Airlines flights from Myrtle Beach Intl. Airport (MYR) to Islip come in to MacArthur Airport (ISP). This is the main gateway to this destination.

Depending on the type of fare you purchased, a fee typically applies if you modify or cancel your booking more than 24 hours after confirmation. To secure plane tickets with more flexibility, select our “Changes included” and “No cancel fee” boxes when searching for flights. To learn more about modifying or canceling your reservation, go to “Trips,” select your flight and tick “Manage Booking.”