$169 Cheap American Airlines flights Pensacola (PNS) to Detroit (DTW)

Finding cheap one-way American Airlines flights from PNS to DTW from $169 on Expedia is a breeze — just filter by "Price (lowest to highest)." Or check out our budget-friendly round-trip fares from $259 for your next exciting adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

For cheap American Airlines fares from Pensacola Intl. Airport (PNS) to Detroit Metropolitan Wayne County Airport (DTW), start searching one to three months before your intended departure. Securing domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also impact what you pay. Sunday is usually the most affordable, while Monday is often the most expensive for domestic flights. You can save 6% on average by booking your trip on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Sort your results by "Early Morning" and "Morning" to browse the earliest flights from PNS to DTW. Setting off early means you're less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.