$239 Cheap American Airlines flights Portland (PWM) to Columbia (CAE)

Landing cheap one-way American Airlines flights from PWM to CAE from $239 on Expedia is a breeze — just filter by "Price (lowest to highest)." Or check out our affordable round-trip fares from $249 for your next adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

To find cheap American Airlines fares from Portland Intl. Jetport Airport (PWM) to Columbia Metropolitan Airport (CAE), start searching one to three months before your planned departure. Securing domestic flights 34 to 86 days in advance could save you 25% compared to booking just 6 to 12 days ahead. The day you book can also influence the price you pay. Sunday is generally the most affordable, while Monday is often the most expensive for domestic flights. You can save 6% on average by choosing to book on a Sunday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

To find the earliest departure from PWM to CAE with American Airlines, filter your results by "Morning" and "Early Morning." Booking an early flight generally means cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.