$866 Cheap American Airlines flights Lyon (LYS) to Columbia (CAE)

Scoring cheap one-way American Airlines flights from LYS to CAE from $866 on Expedia is a cinch --- just filter by "Price (lowest to highest)." Or check out our affordable round-trip fares from $1,473 for your next break.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Landing the best American Airlines deals from LYS to CAE often comes down to booking at the right moment. You can save 17% on international flights when you book 18 to 29 days before takeoff instead of four to five months ahead. As an added bonus, you can pocket 17% on average by buying your tickets on a Sunday rather than a Friday, which is often the most expensive day to book.* It's smart to kick off your flight search about one month before you want to travel.*Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

To find the earliest departure from LYS to CAE with American Airlines, sort your results by "Early Morning" and "Morning." Choosing an early flight generally means you're less likely to experience cancellations.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.