$118 Cheap American Airlines flights San Diego (SAN) to Detroit (DTW)

Finding cheap one-way American Airlines flights from SAN to DTW from $118 on Expedia couldn't be easier — just filter by "Price (lowest to highest)." Alternatively, check out our budget-friendly return fares from $219 for your next adventure.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Look for affordable American Airlines flights from San Diego Intl. Airport (SAN) to Detroit Metropolitan Wayne County Airport (DTW) one to three months ahead of your departure day. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare class and itinerary, the ideal day to book a domestic flight is usually Sunday and the most expensive day tends to be Monday. Passengers who book on a Sunday can save 6% on average compared to those who book on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

Sort your results by "Early Morning" and "Morning" to find the earliest departures from SAN to DTW. Heading off early means flight cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.