$172 Cheap American Airlines flights Santa Fe (SAF) to St. Louis (STL)

Make use of the "Price (lowest to highest)" filter on Expedia to find cheap American Airlines round-trip flights from $244 from SAF to STL. Affordable one-way tickets from $172 are also available.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.

Look for affordable American Airlines flights from Santa Fe Municipal Airport (SAF) to Lambert-St. Louis Intl. Airport (STL) one to three months prior to your departure date. Travelers who book domestic flights 34 to 86 days in advance can save 25% compared to those who book just 6 to 12 days ahead. No matter the fare class and journey, the best day to book a domestic flight is generally Sunday and the most expensive tends to be Monday. Passengers who book on a Sunday can save 6% on average compared to those who book their travel on a Monday.**Ideal booking window recommendation is based on average round-trip ticket prices for January through November for 2024. Best day of the week to book recommendation is based on average round-trip ticket prices for January through October 2024. All data sourced from ARC's global airline sales database.

To find the earliest departure from SAF to STL with American Airlines, filter your results by "Morning" and "Early Morning." Booking an early flight generally means cancellations are less likely.**Most reliable time of the day recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.