Title: The Best 4 Star Hotels in St. Ann, MO from $110 | Expedia.com

[St. Ann Travel Guide](https://expedia.com/St-Ann.dx7051)[Hotels in St. Ann](https://expedia.com/St-Ann-Hotels.d7051.Travel-Guide-Hotels)[Vacation Rentals in St. Ann](https://expedia.com/St-Ann-Vacation-Rentals.d7051.Travel-Guide-VacationRentals)[Flights to St. Ann](https://expedia.com/Cheap-Flights-To-St-Ann.d7051.Travel-Guide-Flights)[Things to do in St. Ann](https://expedia.com/Things-To-Do-In-St-Ann.d7051.Travel-Guide-Activities)[Car Rentals in St. Ann](https://expedia.com/Car-Rentals-In-St-Ann.d7051.Car-Rental-Guide)[St. Ann Vacation Packages](https://expedia.com/St-Ann.d7051.Destination-Travel-Guides)

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## Check availability on St. Ann 4 Star Hotels

Tonight

[Mar 21 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=7051&startDate=2026-03-21&endDate=2026-03-22&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Mar 22 - Mar 23](https://www.expedia.com/Hotel-Search?regionId=7051&startDate=2026-03-22&endDate=2026-03-23&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Mar 27 - Mar 29](https://www.expedia.com/Hotel-Search?regionId=7051&startDate=2026-03-27&endDate=2026-03-29&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two weeks

[Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=7051&startDate=2026-04-03&endDate=2026-04-05&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for St. Ann 4-star hotels

![Restaurant](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/bd7064dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/15dd97ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/bedc886c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/b74ccff9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 21C Museum Hotel St Louis 

[](https://www.expedia.com/St-Louis-Hotels-21C-Museum-Hotel-St-Louis.h89164592.Hotel-Information)

Downtown West

9.0/10

Wonderful

(1,677 reviews)

"Great place to stay. I recommend it and will stay again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Eric

$125 nightly

$146 total

Apr 7 - Apr 8

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-21C-Museum-Hotel-St-Louis.h89164592.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/c1e52387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/020d7f8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Miscellaneous](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/28972a29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/4fd015ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Regency St. Louis at The Arch

[](https://www.expedia.com/St-Louis-Hotels-Hyatt-Regency-St-Louis-At-The-Arch.h14877.Hotel-Information)

Downtown St. Louis

8.4/10

Very Good

(3,980 reviews)

"Very nice stay!!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Beth

$159 nightly

$188 total

Apr 2 - Apr 3

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-Hyatt-Regency-St-Louis-At-The-Arch.h14877.Hotel-Information)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/4700/4672/a81cbeae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4700/4672/879431a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/4700/4672/9ce7fa7f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/4700/4672/95983c36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Renaissance St. Louis Airport Hotel

[](https://www.expedia.com/St-Louis-Hotels-Renaissance-St-Louis-Airport-Hotel.h4672.Hotel-Information)

Berkeley

8.4/10

Very Good

(1,064 reviews)

"Stay was great. Bed was slanted inward and Needs a refresh."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Elizabeth

$127 nightly

$149 total

Apr 3 - Apr 4

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-Renaissance-St-Louis-Airport-Hotel.h4672.Hotel-Information)

![5 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/7000000/6460000/6456500/6456459/71580e9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Pillowtop beds, in-room safe, desk, iron/ironing board](https://images.trvl-media.com/lodging/7000000/6460000/6456500/6456459/30a89ffb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/7000000/6460000/6456500/6456459/4addfd67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Casino](https://images.trvl-media.com/lodging/7000000/6460000/6456500/6456459/427242cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### River City Casino & Hotel

[](https://www.expedia.com/St-Louis-Hotels-River-City-Casino-Hotel.h6456459.Hotel-Information)

St. Louis

9.0/10

Wonderful

(1,488 reviews)

"Great front desk assistance and nice facility with some non-smoking areas!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kimberly

$94 nightly

$110 total

Apr 16 - Apr 17

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-River-City-Casino-Hotel.h6456459.Hotel-Information)

![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/470000/460400/460354/665259c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; Italian cuisine ](https://images.trvl-media.com/lodging/1000000/470000/460400/460354/5e616e8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lounge](https://images.trvl-media.com/lodging/1000000/470000/460400/460354/e3b32092.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/470000/460400/460354/37e5ac68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Westin St. Louis

[](https://www.expedia.com/St-Louis-Hotels-The-Westin-St-Louis.h460354.Hotel-Information)

Downtown St. Louis

8.6/10

Excellent

(1,000 reviews)

"🙂"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Stephanie

$140 nightly

$164 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-The-Westin-St-Louis.h460354.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/40000000/39170000/39161300/39161277/82c4c752.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/40000000/39170000/39161300/39161277/3aed884a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/40000000/39170000/39161300/39161277/4c39e93f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/40000000/39170000/39161300/39161277/bdd2f4e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Live by Loews - St.Louis

[](https://www.expedia.com/St-Louis-Hotels-Live-By-Lowes-StLouis.h39161277.Hotel-Information)

Downtown St. Louis

9.4/10

Exceptional

(1,127 reviews)

"Clean room, helpful staff. Easy check-in and parking"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Beth

$149 nightly

$177 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-Live-By-Lowes-StLouis.h39161277.Hotel-Information)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/70b128db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Nightclub](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/4519749c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/502ee41b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![6 restaurants, breakfast served](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/d825c5c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Ameristar Casino Resort and Spa

[](https://www.expedia.com/St-Louis-Hotels-Ameristar-Casino-Resort-And-Spa.h1873292.Hotel-Information)

St. Charles

8.4/10

Very Good

(1,004 reviews)

"Beautiful rooms, excellent casino "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mary

$184 nightly

$215 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-Ameristar-Casino-Resort-And-Spa.h1873292.Hotel-Information)

![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1090000/1082400/1082373/ce4899f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed | In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1090000/1082400/1082373/15edbb89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed | In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1090000/1082400/1082373/2ff1d9c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1090000/1082400/1082373/b6c6745d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### DoubleTree by Hilton St. Louis Forest Park

[](https://www.expedia.com/St-Louis-Hotels-DoubleTree-By-Hilton-St-Louis-Forest-Park.h1082373.Hotel-Information)

Central West End

8.2/10

Very Good

(1,002 reviews)

"Clean, quiet, and the staff were great"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Cherry

$126 nightly

$148 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-DoubleTree-By-Hilton-St-Louis-Forest-Park.h1082373.Hotel-Information)

![Bar (on property)](https://images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/4b87c2a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/7320679c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/9bdbe023.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/115e2f73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

[](https://www.expedia.com/St-Louis-Hotels-Magnolia-Hotel-St-Louis.h8131949.Hotel-Information)

Downtown St. Louis

8.8/10

Excellent

(1,263 reviews)

"Had a great time, clean room, great food at the bar wonderful historic hotel, lots of nostalgia "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Michael

$121 nightly

$143 total

Mar 29 - Mar 30

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-Magnolia-Hotel-St-Louis.h8131949.Hotel-Information)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/470000/465800/465749/9bee4fd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/470000/465800/465749/e67e5404.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/470000/465800/465749/af72bf51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/470000/465800/465749/b33f7b0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

###  The Royal Sonesta Chase Park Plaza St. Louis

[](https://www.expedia.com/St-Louis-Hotels-The-Chase-Park-Plaza-Royal-Sonesta-St-Louis.h465749.Hotel-Information)

Central West End

9.0/10

Wonderful

(1,000 reviews)

"Beautiful hotel, room was extremely clean and The Preston Restaurant was ordered for room service and the food was awesome!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kamyra

$168 nightly

$198 total

Mar 29 - Mar 30

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-The-Chase-Park-Plaza-Royal-Sonesta-St-Louis.h465749.Hotel-Information)

![3 bars/lounges, rooftop bar](https://images.trvl-media.com/lodging/1000000/20000/12700/12639/e5dc786b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/12700/12639/19fa7016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bars/lounges, rooftop bar](https://images.trvl-media.com/lodging/1000000/20000/12700/12639/e242c22e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bars/lounges, rooftop bar](https://images.trvl-media.com/lodging/1000000/20000/12700/12639/9aac0195.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton St. Louis at the Ballpark

[](https://www.expedia.com/St-Louis-Hotels-Hilton-St-Louis-At-The-Ballpark.h12639.Hotel-Information)

Downtown St. Louis

7.6/10

Good

(1,081 reviews)

"Great property!!!! Close to attractions and anything you need in walking distance. Staff was extremely helpful and kind. Rooms, halls and restaurants very clean!!! Unfortunately, they understaffed for busy check in times. Long lines to valet and check in. Bar staff can’t make basic mixed drinks (old fashioned) so order a can/ bottle. I would stay again for sure!!! Great customer service trumps a mixed drink any time!!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jennifer

$155 nightly

$184 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-Hilton-St-Louis-At-The-Ballpark.h12639.Hotel-Information)

![Property amenity](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/w2897h2195x0y8-cdf51e05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![2 bars/lounges, rooftop bar](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/996a216e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/150f8d2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/10a24838.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Moonrise Hotel

[](https://www.expedia.com/St-Louis-Hotels-Moonrise-Hotel.h2292856.Hotel-Information)

Delmar Loop

9.0/10

Wonderful

(1,915 reviews)

"This place was great! Would stay here again. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Jenna

$158 nightly

$188 total

Apr 14 - Apr 15

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-Moonrise-Hotel.h2292856.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/2000000/1160000/1152200/1152198/w5944h3835x0y5-71dd544c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/2000000/1160000/1152200/1152198/aab55c71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1160000/1152200/1152198/67a05178.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![55-inch flat-screen TV with cable channels, TV, pay movies](https://images.trvl-media.com/lodging/2000000/1160000/1152200/1152198/d4863c7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton Pennywell St. Louis at the Arch

[](https://www.expedia.com/St-Louis-Hotels-Hilton-St-Louis-Downtown-At-The-Arch.h1152198.Hotel-Information)

Downtown St. Louis

8.8/10

Excellent

(1,022 reviews)

"Clean room, staff and the area all excellent"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Oscar Joel

$114 nightly

$134 total

Apr 6 - Apr 7

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-Hilton-St-Louis-Downtown-At-The-Arch.h1152198.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/5000000/4540000/4531500/4531472/d41360b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/5000000/4540000/4531500/4531472/0bea2c07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/5000000/4540000/4531500/4531472/087f88c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/5000000/4540000/4531500/4531472/d86dad87.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Embassy Suites by Hilton St. Louis Downtown

[](https://www.expedia.com/St-Louis-Hotels-Embassy-Suites-By-Hilton-St-Louis-Downtown.h4531472.Hotel-Information)

Downtown St. Louis

8.8/10

Excellent

(1,295 reviews)

"Clean rooms, good breakfast, staff was fantastic!! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Christina

$114 nightly

$136 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-Embassy-Suites-By-Hilton-St-Louis-Downtown.h4531472.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/910000/904800/904712/4c313173.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/910000/904800/904712/567cfa11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/910000/904800/904712/28e08548.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/1000000/910000/904800/904712/146b3f74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Marriott St. Louis Grand

[](https://www.expedia.com/St-Louis-Hotels-Marriott-St-Louis-Grand.h904712.Hotel-Information)

Downtown St. Louis

8.2/10

Very Good

(1,000 reviews)

"Friendly staff, comfy, big, lots of amenities. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Norman

$152 nightly

$181 total

Apr 2 - Apr 3

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-Marriott-St-Louis-Grand.h904712.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/28000000/27620000/27617000/27616925/25bc97a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/28000000/27620000/27617000/27616925/fe6513ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/28000000/27620000/27617000/27616925/8ea3622b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/28000000/27620000/27617000/27616925/b624c396.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

[](https://www.expedia.com/St-Louis-Hotels-Angad-Arts-Hotel-St-Louis.h27616925.Hotel-Information)

Grand Center

8.8/10

Excellent

(1,052 reviews)

"Staff was very friendly- loved all of the art! Room was very clean and bed was nice & comfortable."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tom

$130 nightly

$154 total

Apr 2 - Apr 3

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-Angad-Arts-Hotel-St-Louis.h27616925.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/72000000/71090000/71082600/71082568/937991c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lounge](https://images.trvl-media.com/lodging/72000000/71090000/71082600/71082568/cf784226.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/72000000/71090000/71082600/71082568/f524d74a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/72000000/71090000/71082600/71082568/eba0e02e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### AC Hotel St. Louis Central West End

[](https://www.expedia.com/St-Louis-Hotels-AC-Hotel-St-Louis-Central-West-End.h71082568.Hotel-Information)

Central West End

9.0/10

Wonderful

(720 reviews)

"The hotel is new; very clean, staff are super friendly and great location. This is our second time in 6 months - favorite hotel in central west end!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Patrice

$127 nightly

$150 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-AC-Hotel-St-Louis-Central-West-End.h71082568.Hotel-Information)

![Gastropub](https://images.trvl-media.com/lodging/1000000/30000/26100/26061/24983857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/1000000/30000/26100/26061/w1020h682x1y0-97f5900d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/26100/26061/b6ec06de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/26100/26061/3b7ec090.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Cheshire

[](https://www.expedia.com/St-Louis-Hotels-The-Cheshire.h26061.Hotel-Information)

Richmond Heights

8.6/10

Excellent

(1,000 reviews)

"Bar and restaurant were both great!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

John

$145 nightly

$172 total

Apr 13 - Apr 14

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-The-Cheshire.h26061.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2100/2054/5a4e3056.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2100/2054/68baaab6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Seasonal outdoor pool, open 9:00 AM to 10:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/1000000/10000/2100/2054/6cba1f2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/2100/2054/bdc23fef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hilton St. Louis Frontenac

[](https://www.expedia.com/St-Louis-Hotels-Hilton-St-Louis-Frontenac.h2054.Hotel-Information)

Frontenac

8.8/10

Excellent

(1,001 reviews)

"Excellent stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

William

$147 nightly

$171 total

Apr 5 - Apr 6

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-Hilton-St-Louis-Frontenac.h2054.Hotel-Information)

![Outdoor pool, open 8:00 AM to 8:30 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/3100/3072/295bf6e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/3100/3072/472c2785.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/3100/3072/73dd8f80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lounge](https://images.trvl-media.com/lodging/1000000/10000/3100/3072/fbc92b3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Le Méridien St. Louis Clayton

[](https://www.expedia.com/St-Louis-Hotels-Le-Meridien-St-Louis-Clayton.h3072.Hotel-Information)

Clayton

8.8/10

Excellent

(700 reviews)

"The gym was amazing! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Hannah

$135 nightly

$159 total

Mar 29 - Mar 30

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-Le-Meridien-St-Louis-Clayton.h3072.Hotel-Information)

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## Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in St. Ann.

![The Ritz-Carlton, St. Louis](https://images.trvl-media.com/lodging/1000000/10000/6200/6132/a54897ef_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### The Ritz-Carlton, St. Louis

100 Carondelet Plaza St. Louis MO

$499 nightly

$583 total

Mar 22 - Mar 23

Total with taxes and fees

9.2/10 Wonderful! (560 reviews)

[](https://expedia.com/St-Louis-Hotels-The-Ritz-Carlton.h6132.Hotel-Information)

![Four Seasons Hotel St Louis](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/ef7a5612_y.jpg?impolicy=resizecrop&rw=402&ra=fit)

### Four Seasons Hotel St Louis

999 North Second Street St. Louis MO

$325 nightly

$380 total

Mar 22 - Mar 23

Total with taxes and fees

9.4/10 Exceptional! (1,000 reviews)

[](https://expedia.com/St-Louis-Hotels-Four-Seasons-Hotel-St-Louis.h2851438.Hotel-Information)

Still don't see what you're looking for?

[See all properties in St. Ann.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F22%2F2026&endDate=3%2F23%2F2026&regionId=7051&star=40)

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[Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F22%2F2026&endDate=3%2F23%2F2026&regionId=7051&star=40&star=40&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F22%2F2026&endDate=3%2F23%2F2026&regionId=7051&star=40&star=40&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F22%2F2026&endDate=3%2F23%2F2026&regionId=7051&star=40&star=40&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F22%2F2026&endDate=3%2F23%2F2026&regionId=7051&star=40&star=40&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=3%2F22%2F2026&endDate=3%2F23%2F2026&regionId=7051&star=40&star=40&amenities=WATER_PARK)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Top St. Ann Hotel Reviews

![Renaissance St. Louis Airport Hotel](https://images.trvl-media.com/lodging/1000000/10000/4700/4672/a81cbeae_y.jpg)

### Renaissance St. Louis Airport Hotel

10/10 Excellent

"It’s good "

[](https://expedia.com/St-Louis-Hotels-Renaissance-St-Louis-Airport-Hotel.h4672.Hotel-Information)

![Hyatt Regency St. Louis at The Arch](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/c1e52387_y.jpg)

### Hyatt Regency St. Louis at The Arch

10/10 Excellent

"Good"

[](https://expedia.com/St-Louis-Hotels-Hyatt-Regency-St-Louis-At-The-Arch.h14877.Hotel-Information)

![River City Casino & Hotel](https://images.trvl-media.com/lodging/7000000/6460000/6456500/6456459/71580e9e_y.jpg)

### River City Casino & Hotel

10/10 Excellent

"Perfect "

[](https://expedia.com/St-Louis-Hotels-River-City-Casino-Hotel.h6456459.Hotel-Information)

![Live by Loews - St.Louis](https://images.trvl-media.com/lodging/40000000/39170000/39161300/39161277/82c4c752_y.jpg)

### Live by Loews - St.Louis

10/10 Excellent

"Clean room, helpful staff. Easy check-in and parking"

[](https://expedia.com/St-Louis-Hotels-Live-By-Lowes-StLouis.h39161277.Hotel-Information)

## Find out more about St. Ann

## St. Ann Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in St. Ann, St. Louis are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the St. Ann 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in St. Ann. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in St. Ann, St. Louis, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star St. Ann hotels offer everything your heart desires.

## Frequently asked questions

### What are the best 4-star hotels in St. Ann?

### How much does it cost to stay in a 4-star hotel in St. Ann?

> - Search for the lowest price from $380

### What's the difference between 5-star and 4-star hotels in St. Ann?

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- [Flights from Reno (RNO) to St. Louis (STL) ](https://www.expedia.com/lp/flights/rno/stl/reno-to-st-louis)

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