Title: The Best 4 Star Hotels in St. Ann, MO from $136 | Expedia.com [St. Ann Travel Guide](https://expedia.com/St-Ann.dx7051)[Hotels in St. Ann](https://expedia.com/St-Ann-Hotels.d7051.Travel-Guide-Hotels)[Vacation Rentals in St. Ann](https://expedia.com/St-Ann-Vacation-Rentals.d7051.Travel-Guide-VacationRentals)[Flights to St. Ann](https://expedia.com/Cheap-Flights-To-St-Ann.d7051.Travel-Guide-Flights)[Things to do in St. Ann](https://expedia.com/Things-To-Do-In-St-Ann.d7051.Travel-Guide-Activities)[Car Rentals in St. Ann](https://expedia.com/Car-Rentals-In-St-Ann.d7051.Car-Rental-Guide)[St. Ann Vacation Packages](https://expedia.com/St-Ann.d7051.Destination-Travel-Guides) ![Rafting on the White River in St Ann, Jamaica.](https://images.trvl-media.com/place/7051/588b6ad5-b230-4dde-ac52-51c986f68965.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/7051/588b6ad5-b230-4dde-ac52-51c986f68965.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on St. Ann 4 Star Hotels Tonight [Apr 1 - Apr 2](https://www.expedia.com/Hotel-Search?regionId=7051&startDate=2026-04-01&endDate=2026-04-02&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Apr 2 - Apr 3](https://www.expedia.com/Hotel-Search?regionId=7051&startDate=2026-04-02&endDate=2026-04-03&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=7051&startDate=2026-04-03&endDate=2026-04-05&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=7051&startDate=2026-04-10&endDate=2026-04-12&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for St. Ann 4-star hotels ![Restaurant](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/bd7064dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/bedc886c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Massages](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/80c5fbe4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89170000/89164600/89164592/15dd97ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 21C Museum Hotel St Louis [](https://www.expedia.com/St-Louis-Hotels-21C-Museum-Hotel-St-Louis.h89164592.Hotel-Information) Downtown West 9.0/10 Wonderful (1,707 reviews) "Beautiful hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rebecca $153 nightly $179 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-21C-Museum-Hotel-St-Louis.h89164592.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/c1e52387.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/8a4b681b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/4fd015ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/020d7f8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Regency St. Louis at The Arch [](https://www.expedia.com/St-Louis-Hotels-Hyatt-Regency-St-Louis-At-The-Arch.h14877.Hotel-Information) Downtown St. Louis 8.6/10 Excellent (3,986 reviews) "Great hotel in a prime location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Preston $169 nightly $199 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-Hyatt-Regency-St-Louis-At-The-Arch.h14877.Hotel-Information) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/4700/4672/a81cbeae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/10000/4700/4672/95983c36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (USD 23 per person)](https://images.trvl-media.com/lodging/1000000/10000/4700/4672/a4621b64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/4700/4672/879431a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Renaissance St. Louis Airport Hotel [](https://www.expedia.com/St-Louis-Hotels-Renaissance-St-Louis-Airport-Hotel.h4672.Hotel-Information) Berkeley 8.4/10 Very Good (1,070 reviews) "Great place to stay " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Timothy $125 nightly $146 total Apr 4 - Apr 5 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-Renaissance-St-Louis-Airport-Hotel.h4672.Hotel-Information) ![5 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/7000000/6460000/6456500/6456459/71580e9e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/7000000/6460000/6456500/6456459/427242cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Nightclub](https://images.trvl-media.com/lodging/7000000/6460000/6456500/6456459/76f0d401.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6460000/6456500/6456459/4addfd67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### River City Casino & Hotel [](https://www.expedia.com/St-Louis-Hotels-River-City-Casino-Hotel.h6456459.Hotel-Information) St. Louis 9.0/10 Wonderful (1,510 reviews) "Great place with lots of restaurants " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dennis $117 nightly $136 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-River-City-Casino-Hotel.h6456459.Hotel-Information) ![Premium bedding, down comforters, pillowtop beds, in-room safe](https://images.trvl-media.com/lodging/1000000/470000/460400/460354/665259c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/470000/460400/460354/37e5ac68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Italian cuisine ](https://images.trvl-media.com/lodging/1000000/470000/460400/460354/5e616e8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/470000/460400/460354/eb286ce8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Westin St. Louis [](https://www.expedia.com/St-Louis-Hotels-The-Westin-St-Louis.h460354.Hotel-Information) Downtown St. Louis 8.6/10 Excellent (1,009 reviews) "Always a good stay at the Westin" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeremy $136 nightly $158 total Apr 19 - Apr 20 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-The-Westin-St-Louis.h460354.Hotel-Information) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/40000000/39170000/39161300/39161277/4c39e93f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/40000000/39170000/39161300/39161277/82c4c752.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch and dinner served](https://images.trvl-media.com/lodging/40000000/39170000/39161300/39161277/3aed884a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/40000000/39170000/39161300/39161277/bdd2f4e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Live by Loews - St.Louis [](https://www.expedia.com/St-Louis-Hotels-Live-By-Lowes-StLouis.h39161277.Hotel-Information) Downtown St. Louis 9.4/10 Exceptional (1,135 reviews) "The staff was friendly, accommodating and helpful. Hotel was clean and comfortable. I would stay here again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anthony W. $149 nightly $177 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-Live-By-Lowes-StLouis.h39161277.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/70b128db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/w2880h1936x0y0-34b8c827.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Nightclub](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/4519749c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1880000/1873300/1873292/502ee41b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Ameristar Casino Resort and Spa [](https://www.expedia.com/St-Louis-Hotels-Ameristar-Casino-Resort-And-Spa.h1873292.Hotel-Information) St. Charles 8.4/10 Very Good (1,001 reviews) "Love this location. Our favorite place to stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph $193 nightly $226 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-Ameristar-Casino-Resort-And-Spa.h1873292.Hotel-Information) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1090000/1082400/1082373/ce4899f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed | In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1090000/1082400/1082373/2ff1d9c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed | In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1090000/1082400/1082373/15edbb89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily buffet breakfast (USD 14.50 per person)](https://images.trvl-media.com/lodging/2000000/1090000/1082400/1082373/8de3247b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton St. Louis Forest Park [](https://www.expedia.com/St-Louis-Hotels-DoubleTree-By-Hilton-St-Louis-Forest-Park.h1082373.Hotel-Information) Central West End 8.2/10 Very Good (1,002 reviews) "The room was clean and comfortable, the staff was friendly and accommodating. Perfect for our stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rebecca $130 nightly $154 total Apr 19 - Apr 20 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-DoubleTree-By-Hilton-St-Louis-Forest-Park.h1082373.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/4b87c2a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/115e2f73.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; American cuisine ](https://images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/3e253a01.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/9000000/8140000/8132000/8131949/9bdbe023.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Magnolia Hotel St. Louis, a Tribute Portfolio Hotel [](https://www.expedia.com/St-Louis-Hotels-Magnolia-Hotel-St-Louis.h8131949.Hotel-Information) Downtown St. Louis 8.8/10 Excellent (1,269 reviews) "Great place to stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael $124 nightly $147 total Apr 8 - Apr 9 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-Magnolia-Hotel-St-Louis.h8131949.Hotel-Information) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/470000/465800/465749/9bee4fd7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/470000/465800/465749/b33f7b0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/470000/465800/465749/e67e5404.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/470000/465800/465749/34e1f351.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Royal Sonesta Chase Park Plaza St. Louis [](https://www.expedia.com/St-Louis-Hotels-The-Chase-Park-Plaza-Royal-Sonesta-St-Louis.h465749.Hotel-Information) Central West End 9.0/10 Wonderful (1,009 reviews) "Beautiful hotel, room was extremely clean and The Preston Restaurant was ordered for room service and the food was awesome!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kamyra $184 nightly $217 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-The-Chase-Park-Plaza-Royal-Sonesta-St-Louis.h465749.Hotel-Information) ![3 bars/lounges, rooftop bar](https://images.trvl-media.com/lodging/1000000/20000/12700/12639/e5dc786b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, rooftop bar](https://images.trvl-media.com/lodging/1000000/20000/12700/12639/9aac0195.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/20000/12700/12639/19fa7016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Rooftop terrace](https://images.trvl-media.com/lodging/1000000/20000/12700/12639/0f677423.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton St. Louis at the Ballpark [](https://www.expedia.com/St-Louis-Hotels-Hilton-St-Louis-At-The-Ballpark.h12639.Hotel-Information) Downtown St. Louis 7.6/10 Good (1,089 reviews) "Alles was prima in orde, nette staf, goed ontbijt, prima hotel" ![Netherlands](https://a.travel-assets.com/egds/marks/flags/nl.svg) Marcel $171 nightly $204 total Apr 19 - Apr 20 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-Hilton-St-Louis-At-The-Ballpark.h12639.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/w2897h2195x0y8-cdf51e05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/10a24838.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/1004381f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/3000000/2300000/2292900/2292856/150f8d2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Moonrise Hotel [](https://www.expedia.com/St-Louis-Hotels-Moonrise-Hotel.h2292856.Hotel-Information) Delmar Loop 9.0/10 Wonderful (1,913 reviews) "Great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John $174 nightly $206 total Apr 13 - Apr 14 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-Moonrise-Hotel.h2292856.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/2000000/1160000/1152200/1152198/w5944h3835x0y5-71dd544c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1160000/1152200/1152198/67a05178.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/2000000/1160000/1152200/1152198/aab55c71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch flat-screen TV with cable channels, TV, pay movies](https://images.trvl-media.com/lodging/2000000/1160000/1152200/1152198/d4863c7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton Pennywell St. Louis at the Arch [](https://www.expedia.com/St-Louis-Hotels-Hilton-St-Louis-Downtown-At-The-Arch.h1152198.Hotel-Information) Downtown St. Louis 8.8/10 Excellent (1,024 reviews) "Great service and friendly staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Douglas $128 nightly $151 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-Hilton-St-Louis-Downtown-At-The-Arch.h1152198.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/5000000/4540000/4531500/4531472/d41360b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/5000000/4540000/4531500/4531472/0bea2c07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/5000000/4540000/4531500/4531472/721547ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served, American cuisine](https://images.trvl-media.com/lodging/5000000/4540000/4531500/4531472/087f88c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites by Hilton St. Louis Downtown [](https://www.expedia.com/St-Louis-Hotels-Embassy-Suites-By-Hilton-St-Louis-Downtown.h4531472.Hotel-Information) Downtown St. Louis 8.8/10 Excellent (1,298 reviews) "Clean rooms, good breakfast, staff was fantastic!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christina $122 nightly $145 total Apr 19 - Apr 20 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-Embassy-Suites-By-Hilton-St-Louis-Downtown.h4531472.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/910000/904800/904712/4c313173.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/910000/904800/904712/146b3f74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/1000000/910000/904800/904712/11973fba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/910000/904800/904712/567cfa11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marriott St. Louis Grand [](https://www.expedia.com/St-Louis-Hotels-Marriott-St-Louis-Grand.h904712.Hotel-Information) Downtown St. Louis 8.2/10 Very Good (1,001 reviews) "Everything is excellent. Always a good stay here." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carolyn $152 nightly $181 total Apr 18 - Apr 19 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-Marriott-St-Louis-Grand.h904712.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/28000000/27620000/27617000/27616925/25bc97a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/28000000/27620000/27617000/27616925/b624c396.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/28000000/27620000/27617000/27616925/fe6513ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Bathtub, Corner | Egyptian cotton sheets, premium bedding, down comforters, pillowtop beds](https://images.trvl-media.com/lodging/28000000/27620000/27617000/27616925/0864b113.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Angad Arts Hotel St. Louis, Tapestry Collection by Hilton [](https://www.expedia.com/St-Louis-Hotels-Angad-Arts-Hotel-St-Louis.h27616925.Hotel-Information) Grand Center 8.8/10 Excellent (1,045 reviews) "Room was absolutely beautiful, very clean and spacious!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shawnica $122 nightly $144 total Apr 6 - Apr 7 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-Angad-Arts-Hotel-St-Louis.h27616925.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/72000000/71090000/71082600/71082568/937991c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/72000000/71090000/71082600/71082568/eba0e02e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/72000000/71090000/71082600/71082568/cf784226.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/72000000/71090000/71082600/71082568/4b03f0f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AC Hotel St. Louis Central West End [](https://www.expedia.com/St-Louis-Hotels-AC-Hotel-St-Louis-Central-West-End.h71082568.Hotel-Information) Central West End 9.0/10 Wonderful (728 reviews) "Many thanks to Renya and Queen at the front desk." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deniz $131 nightly $154 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-AC-Hotel-St-Louis-Central-West-End.h71082568.Hotel-Information) ![Gastropub](https://images.trvl-media.com/lodging/1000000/30000/26100/26061/24983857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/30000/26100/26061/b6ec06de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Aerial view](https://images.trvl-media.com/lodging/1000000/30000/26100/26061/c3a4349f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/26100/26061/3b7ec090.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Cheshire [](https://www.expedia.com/St-Louis-Hotels-The-Cheshire.h26061.Hotel-Information) Richmond Heights 8.6/10 Excellent (1,000 reviews) "Bar and restaurant were both great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) John $153 nightly $182 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-The-Cheshire.h26061.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2100/2054/058067f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 9:00 AM to 10:00 PM, pool umbrellas](https://images.trvl-media.com/lodging/1000000/10000/2100/2054/6cba1f2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/10000/2100/2054/4edda6a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/10000/2100/2054/86426a62.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hilton St. Louis Frontenac [](https://www.expedia.com/St-Louis-Hotels-Hilton-St-Louis-Frontenac.h2054.Hotel-Information) Frontenac 8.8/10 Excellent (1,000 reviews) "Great service, nice clean rooms, tasty restaurant & great location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Teri $147 nightly $171 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-Hilton-St-Louis-Frontenac.h2054.Hotel-Information) ![Outdoor pool, open 8:00 AM to 8:30 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/3100/3072/295bf6e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/3100/3072/73dd8f80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/10000/3100/3072/472c2785.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lounge](https://images.trvl-media.com/lodging/1000000/10000/3100/3072/fbc92b3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Le Méridien St. Louis Clayton [](https://www.expedia.com/St-Louis-Hotels-Le-Meridien-St-Louis-Clayton.h3072.Hotel-Information) Clayton 8.8/10 Excellent (704 reviews) "Clean room & good included breakfast " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Felix $143 nightly $169 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/St-Louis-Hotels-Le-Meridien-St-Louis-Clayton.h3072.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-St-Ann-Hotels.s40-0-d7051.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-St-Ann-Hotels.s40-0-d7051.Travel-Guide-Filter-Hotels) ## Explore similar 5-star hotels Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in St. Ann. ![The Ritz-Carlton, St. Louis](https://images.trvl-media.com/lodging/1000000/10000/6200/6132/a54897ef_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### The Ritz-Carlton, St. Louis 100 Carondelet Plaza St. Louis MO $499 nightly $583 total Apr 5 - Apr 6 Total with taxes and fees 9.2/10 Wonderful! (562 reviews) [](https://expedia.com/St-Louis-Hotels-The-Ritz-Carlton.h6132.Hotel-Information) ![Four Seasons Hotel St Louis](https://images.trvl-media.com/lodging/3000000/2860000/2851500/2851438/ef7a5612_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Four Seasons Hotel St Louis 999 North Second Street St. Louis MO $470 nightly $550 total Apr 2 - Apr 3 Total with taxes and fees 9.4/10 Exceptional! (1,000 reviews) [](https://expedia.com/St-Louis-Hotels-Four-Seasons-Hotel-St-Louis.h2851438.Hotel-Information) Still don't see what you're looking for? [See all properties in St. Ann.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=4%2F2%2F2026&endDate=4%2F3%2F2026®ionId=7051&star=40) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=4%2F2%2F2026&endDate=4%2F3%2F2026®ionId=7051&star=40&star=40&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=4%2F2%2F2026&endDate=4%2F3%2F2026®ionId=7051&star=40&star=40&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=4%2F2%2F2026&endDate=4%2F3%2F2026®ionId=7051&star=40&star=40&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=4%2F2%2F2026&endDate=4%2F3%2F2026®ionId=7051&star=40&star=40&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=4%2F2%2F2026&endDate=4%2F3%2F2026®ionId=7051&star=40&star=40&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about St. Ann Families gather for outdoor concerts and community events at Tiemeyer Park's amphitheater during warm months. Nearby St. Louis offers additional attractions like the Gateway Arch and Forest Park's free zoo. [See all hotels in St. Ann](https://www.expedia.com/Hotel-Search?startDate=2026-04-15&endDate=2026-04-16&adults=2®ionId=7051) ![Rafting on the White River in St Ann, Jamaica.](https://images.trvl-media.com/place/7051/588b6ad5-b230-4dde-ac52-51c986f68965.jpg?impolicy=fcrop&w=900&h=600&p=1&q=high) ## Top St. Ann Hotel Reviews ![Hyatt Regency St. Louis at The Arch](https://images.trvl-media.com/lodging/1000000/20000/14900/14877/c1e52387_y.jpg) ### Hyatt Regency St. Louis at The Arch 10/10 Excellent "The front desk associates were amazing! The valet attendants were amazing! Dinner at Ruth Chris was amazing! We enjoyed our stay!" [](https://expedia.com/St-Louis-Hotels-Hyatt-Regency-St-Louis-At-The-Arch.h14877.Hotel-Information) ![Live by Loews - St.Louis](https://images.trvl-media.com/lodging/40000000/39170000/39161300/39161277/82c4c752_y.jpg) ### Live by Loews - St.Louis 10/10 Excellent "Very safe and exciting location. Loved staying here. Smells clean and inviting. Someone was always ready and willing to help. Quiet, clean, easy. Stayed with two elementary aged children and they loved being so close to the play area at Ballpark Village." [](https://expedia.com/St-Louis-Hotels-Live-By-Lowes-StLouis.h39161277.Hotel-Information) ![River City Casino & Hotel](https://images.trvl-media.com/lodging/7000000/6460000/6456500/6456459/71580e9e_y.jpg) ### River City Casino & Hotel 2/10 Terrible "My room was extremely dusty The night stand the counters all full of dust. It’s very odd " [](https://expedia.com/St-Louis-Hotels-River-City-Casino-Hotel.h6456459.Hotel-Information) ![Renaissance St. Louis Airport Hotel](https://images.trvl-media.com/lodging/1000000/10000/4700/4672/a81cbeae_y.jpg) ### Renaissance St. Louis Airport Hotel 2/10 Terrible "The day I arrived I clearly showed I rented 2 separate rooms. Manager couldnt hlep me fix issue. I called hotel.com to fix problem. The agent kept calling front desk and they wouldnt answer. I tried to put the manager on the phone from my cell but manager denied. And told the agent to call the front desk. But hell they wouldnt answer it. I went to sit in the car till the agent finally spoke to them. Took 1 1/2 to resolve. Room had a big hole in the bed skirt. The bathroom shower knob pulls off. Shower handle didnt work. They came to clean room took all the towels and didnt replace. Worst experience I have ever had. Next time ill go down the road and pay them $788.00." [](https://expedia.com/St-Louis-Hotels-Renaissance-St-Louis-Airport-Hotel.h4672.Hotel-Information) ## Find out more about St. Ann ## St. Ann Four Star Hotel Information When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in St. Ann, St. Louis are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the St. Ann 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service. Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in St. Ann. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in St. Ann, St. Louis, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop. Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star St. Ann hotels offer everything your heart desires. ## Frequently asked questions ### What are the best 4-star hotels in St. Ann? ### How much does it cost to stay in a 4-star hotel in St. Ann? > - Search for the lowest price from $550 ### What's the difference between 5-star and 4-star hotels in St. Ann? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - [Hotels near Lambert-St. Louis Intl. ](https://www.expedia.com/Lambert-St-Louis-Intl-Airport-Hotels.0-aSTL-0.Travel-Guide-Filter-Hotels) - [4 Star Hotels in Edmundson ](https://www.expedia.com/4Star-Edmundson-St-Louis-Hotels.s40-n8173-0.Travel-Guide-Filter-Hotels) - [Flights from Lambert-St. Louis Intl. ](https://www.expedia.com/lp/airports/stl/flights-from-lambert-st-louis-intl-airport) - [Flights from Chicago (ORD) to St. Louis (STL) ](https://www.expedia.com/lp/flights/ord/stl/chicago-to-st-louis) - 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[Flights from Tucson (TUS) to St. Louis (STL) ](https://www.expedia.com/lp/flights/tus/stl/tucson-to-st-louis) - [Flights from Dayton (DAY) to St. Louis (STL) ](https://www.expedia.com/lp/flights/day/stl/dayton-to-st-louis) - [Flights from Savannah (SAV) to St. Louis (STL) ](https://www.expedia.com/lp/flights/sav/stl/savannah-to-st-louis) - [Flights from Colorado Springs (COS) to St. Louis (STL) ](https://www.expedia.com/lp/flights/cos/stl/colorado-springs-to-st-louis) - [Flights from Birmingham (BHM) to St. Louis (STL) ](https://www.expedia.com/lp/flights/bhm/stl/birmingham-to-st-louis) - [Flights from Albany (ALB) to St. Louis (STL) ](https://www.expedia.com/lp/flights/alb/stl/albany-to-st-louis) - [Flights to Lambert-St. Louis Intl. ](https://www.expedia.com/Cheap-Flights-To-Lambert-St-Louis-Intl.d5002323.Travel-Guide-Flights) - [Flights from Boise (BOI) to St. Louis (STL) ](https://www.expedia.com/lp/flights/boi/stl/boise-to-st-louis) - [Flights from Branson (BKG) to St. Louis (STL) ](https://www.expedia.com/lp/flights/bkg/stl/branson-to-st-louis) - [Flights from Honolulu (HNL) to St. Louis (STL) ](https://www.expedia.com/lp/flights/hnl/stl/honolulu-to-st-louis) - [Flights from Pensacola (PNS) to St. Louis (STL) ](https://www.expedia.com/lp/flights/pns/stl/pensacola-to-st-louis) - [Flights from Columbia (COU) to St. Louis (STL) ](https://www.expedia.com/lp/flights/cou/stl/columbia-to-st-louis) - [Flights from Greenville (GSP) to St. Louis (STL) ](https://www.expedia.com/lp/flights/gsp/stl/greenville-to-st-louis) - [Flights from West Palm Beach (PBI) to St. Louis (STL) ](https://www.expedia.com/lp/flights/pbi/stl/west-palm-beach-to-st-louis) - [Flights from Lexington (LEX) to St. Louis (STL) ](https://www.expedia.com/lp/flights/lex/stl/lexington-to-st-louis) - [Flights from Columbia (CAE) to St. Louis (STL) ](https://www.expedia.com/lp/flights/cae/stl/columbia-to-st-louis) - [Flights from Asheville (AVL) to St. Louis (STL) ](https://www.expedia.com/lp/flights/avl/stl/asheville-to-st-louis) - [Flights from Rochester (ROC) to St. Louis (STL) ](https://www.expedia.com/lp/flights/roc/stl/rochester-to-st-louis) - 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